The document discusses the results of a study on the effects of a new drug on memory and cognitive function in older adults. The double-blind study involved giving either the new drug or a placebo to 100 volunteers aged 65-80 over a 6 month period. Testing showed those receiving the drug experienced statistically significant improvements in short-term memory retention and processing speed compared to the placebo group.
In this lecture, we present the main reactions of Kreb's cycle and its clinical importance.
Most of the slides are cited from Lippincott's illustrated Biochemistry and Satyrana Biochemistry.
Best Bishes,
Dr. Haroon
In this section, we describe Glycolysis and its clinical importance and most of the slides are cited from:
1- Lippincott Biochemistry 7th edition
2- Satyrana Biochemistry
3- Harper Biochemistry
In this section, we describe different types of receptors. Most of the slides are cited from Lippincott's Illustrated Review Biochemistry. Other references include:
U. Satyrana Biochemistry
Harper's Biochmeistry
In this section, we describe enzymes. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
3. Harper's Biochemistry
In this section, we describe digestion and absorption of Nucleic Acids and Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyran Biochemistry
Dr. Haroon
In this section we describe nucleotides and most of the slides are cited from:
Lippincott's Illustrated Review Biochemistry
U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe digestion and absorption of proteins.
Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe plasma proteins. Most of the slides are cited from:
1. Lippincott's illustrated Review Biochemistry
2. Harper's Biochemistry
3. U. Satyrana Biochemistry
In this lecture, we present the main reactions of Kreb's cycle and its clinical importance.
Most of the slides are cited from Lippincott's illustrated Biochemistry and Satyrana Biochemistry.
Best Bishes,
Dr. Haroon
In this section, we describe Glycolysis and its clinical importance and most of the slides are cited from:
1- Lippincott Biochemistry 7th edition
2- Satyrana Biochemistry
3- Harper Biochemistry
In this section, we describe different types of receptors. Most of the slides are cited from Lippincott's Illustrated Review Biochemistry. Other references include:
U. Satyrana Biochemistry
Harper's Biochmeistry
In this section, we describe enzymes. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
3. Harper's Biochemistry
In this section, we describe digestion and absorption of Nucleic Acids and Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyran Biochemistry
Dr. Haroon
In this section we describe nucleotides and most of the slides are cited from:
Lippincott's Illustrated Review Biochemistry
U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe digestion and absorption of proteins.
Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe plasma proteins. Most of the slides are cited from:
1. Lippincott's illustrated Review Biochemistry
2. Harper's Biochemistry
3. U. Satyrana Biochemistry
In this section, we describe proteins biochemistry. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U Satyran Biochemistry
3. Harper's Biochemistry
Dr. Haroon
In this presentation, we describe drugs used for allergic rhinitis and cough and most of the slides are cited from:
1. Lippincott's Pharmacology
2. KD Triphati Pharmacology
2. Basic Pharmacology
For further slides, you can email me at: haroonstanikzai1@gmail.com
Thank you
Dr. Haroon
In this section, we describe peptides and most of the slides are cited from:
1- Lippincott's Illustrated Review Biochemistry
2- Harper's Biochemistry
3- U. Satyr Ana Biochemistry
In this section We describe drugs used in Asthma and COPD and Most of the slides are prescribed from Lippincott's Pharmacology. Other references include:
1. Kd triphati Pharmacology
2. Basic Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
n this section, we describe Drugs used in Vomiting and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Drugs used in Constipation and Diarrhea and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Digestion and Absorption of Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe drugs used for peptic ulcer diseases.
Most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this presentation, we describe Anti-Histamine drugs along with histamine physiology.
Most slides are cited from Lippincott's Pharmacology
Other references include:
Kd Triphati Pharmacology
Thank you,
In this section, we describe Introduction to Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe:
- Digestion and Absorption of Carbohydrates
Most of the slides are cited from:
1. Lippincott's Biochemistry
2. Stayaran's Biochemistry
3. Jaypee Biochemistry
In this section, we describe Disaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Important monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Reactions of Monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe structural aspects of monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
In this section, we describe proteins biochemistry. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U Satyran Biochemistry
3. Harper's Biochemistry
Dr. Haroon
In this presentation, we describe drugs used for allergic rhinitis and cough and most of the slides are cited from:
1. Lippincott's Pharmacology
2. KD Triphati Pharmacology
2. Basic Pharmacology
For further slides, you can email me at: haroonstanikzai1@gmail.com
Thank you
Dr. Haroon
In this section, we describe peptides and most of the slides are cited from:
1- Lippincott's Illustrated Review Biochemistry
2- Harper's Biochemistry
3- U. Satyr Ana Biochemistry
In this section We describe drugs used in Asthma and COPD and Most of the slides are prescribed from Lippincott's Pharmacology. Other references include:
1. Kd triphati Pharmacology
2. Basic Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
n this section, we describe Drugs used in Vomiting and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Drugs used in Constipation and Diarrhea and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Digestion and Absorption of Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe drugs used for peptic ulcer diseases.
Most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this presentation, we describe Anti-Histamine drugs along with histamine physiology.
Most slides are cited from Lippincott's Pharmacology
Other references include:
Kd Triphati Pharmacology
Thank you,
In this section, we describe Introduction to Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe:
- Digestion and Absorption of Carbohydrates
Most of the slides are cited from:
1. Lippincott's Biochemistry
2. Stayaran's Biochemistry
3. Jaypee Biochemistry
In this section, we describe Disaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Important monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Reactions of Monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe structural aspects of monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
