This document provides an overview of the content that will be covered in a course on Instrumentation and Laboratory Animal Science. It discusses the history of animal experimentation from ancient times to modern developments. It also examines the ethical, scientific, and legal issues surrounding the use of animals in research. The 3Rs concept of replacement, reduction and refinement is introduced to minimize harm to animals. Common laboratory animals like mice and rats are described. The course will cover topics like anesthesia, euthanasia, administration of substances, and collection of bodily samples in animal experiments.