RMsis is a JIRA plugin for requirement management that supports JIRA versions 6.0 to 7.3.3. It requires Java 1.7 or 1.8, and supports several databases and web browsers. Installation involves installing JIRA if needed, creating a database for RMsis, installing the RMsis plugin, and activating a license. Configuration covers the JIRA URL, database, email, and RMsis server settings. Trial and purchased licenses can be generated through the Optimizory website.