Injury Location Not the Real Problem?
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Part I of interview with the 2015 National Strength and Conditioning Association's Sports Medicine/Rehabilitation Specialist of the Year, Dr. Arianne Missimer!
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8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
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We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.NVBDCP.pptx Nation vector borne disease control program
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Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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Injury Location Not the Real Problem?
- 1. How Movement Is The Bridge To Performance Featuring: Dr. Arianne Missimer, DPT, RD, SFG2, CICS, CSCS, TPI-MP3, K-Vest2, RockDoc, FMS/SFMA, NKT 1 “2015 NSCA Sports Medicine and Rehabilitation Specialist of the Year”
- 3. I have spent the past 16 years in the fitness and nutrition industry! 5 of those in rehabilitation specializing in: performance enhancement and injury prevention through proper assessment and training methods. www.kineticseminars.com
- 4. I have owned and operated a performance training studio for the past 13 years training individuals seeking a healthier lifestyle as well as recreational and competitive athletes of all levels. www.kineticseminars.com
- 5. I realized many people were entering a fitness program with pain and injury… www.kineticseminars.com
- 6. My passion for performance training and movement and the quest for understanding the effects of pain and injury on movement led me to pursue my Doctorate of Physical Therapy. I love going to continuing education courses to understand and apply different movement- based principles that will help better the outcomes of my patients! www.kineticseminars.com
- 7. My approach is actually quite simple. I do not just look at the location of injury... www.kineticseminars.com
- 8. 1. I look at functional movement patterns developed by the CNS to determine the root of movement dysfunction. 2. I find what compensation patterns are contributing to the source of the pain. www.kineticseminars.com
- 10. Part II of this interview coming soon! Movement Quality and Identifying the “Gap Between Performance and Rehabilitation” www.kineticseminars.com
- 11. Arianne Missimer is the creator of The Movement Paradigm course hosted by Kinetic Seminars. February 20-21, 2016 www.kineticseminars.com