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Plate Round Discussion 1/10/24
• Case 1: Pasteurella Bacteremia
• Case 2: GPB from gunshot wound/intra-abdominal abscess
• Case 3:Mycobacterium haemophilum
Pasteurella Multocida
• Named after Louis Pasteur (1822-
1895), chemist and bacteriologist in
Paris
• Part of the normal flora of the
respiratory tract in animals
• Through contact with these animals
(licking, biting and scratching),
humans can be infected, often by
cats and dogs.
• P. multocida the most virulent
Diagnostic testing
• Gram negative bacillus
• Oxidase positive, indole positive, catalase
positive.
• Demonstrate growth on SBA but not on MAC.
• Susceptibility: Testing NOT performed.
Predictably susceptible to penicillin, ampicillin,
broad-spectrum penicillin, second and third
generation cephalosporins, tetracycline and
chloramphenicol
Mycobacterium
Fortuitum /GPB
Bacteremia
• fast-growing non-tuberculous mycobacteria (NTM) that is found in the environment
(found in soil and water)
• referred to as “acid-fast bacteria,” a term referencing their response to a laboratory
staining technique.
• Contaminated ice machines are a relatively important hospital reservoir for the Rapid
Growing Mycobacteria
Diagnostic testing
• Gram-positive, nonmotile and acid-fast rods
• Colonies are white, rough and wrinkled
• Obligate aerobic
Mycobacterium haemophilum
• Short, occasionally curved, gram-positive,
nonmotile and strongly acid-fast rods.
• Nonpigmented and rough to smooth colonies.
• Is an aerobic fastidious organism that grows best
at 30–32°C and is a slow-growing organism first
identified in 1978
• Growth also depends on the presence of iron or
haemin, which is a unique feature. Because of this
requirement, it will not grow with standard
isolation techniques for other mycobacteria
HSV
Esophageal Ulcer
Infectious Diseases Plate Rounds 1-10-24.pptx
Infectious Diseases Plate Rounds 1-10-24.pptx
Infectious Diseases Plate Rounds 1-10-24.pptx
Infectious Diseases Plate Rounds 1-10-24.pptx

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Infectious Diseases Plate Rounds 1-10-24.pptx

  • 1. Plate Round Discussion 1/10/24 • Case 1: Pasteurella Bacteremia • Case 2: GPB from gunshot wound/intra-abdominal abscess • Case 3:Mycobacterium haemophilum
  • 2. Pasteurella Multocida • Named after Louis Pasteur (1822- 1895), chemist and bacteriologist in Paris • Part of the normal flora of the respiratory tract in animals • Through contact with these animals (licking, biting and scratching), humans can be infected, often by cats and dogs. • P. multocida the most virulent
  • 3. Diagnostic testing • Gram negative bacillus • Oxidase positive, indole positive, catalase positive. • Demonstrate growth on SBA but not on MAC. • Susceptibility: Testing NOT performed. Predictably susceptible to penicillin, ampicillin, broad-spectrum penicillin, second and third generation cephalosporins, tetracycline and chloramphenicol
  • 4. Mycobacterium Fortuitum /GPB Bacteremia • fast-growing non-tuberculous mycobacteria (NTM) that is found in the environment (found in soil and water) • referred to as “acid-fast bacteria,” a term referencing their response to a laboratory staining technique. • Contaminated ice machines are a relatively important hospital reservoir for the Rapid Growing Mycobacteria
  • 5. Diagnostic testing • Gram-positive, nonmotile and acid-fast rods • Colonies are white, rough and wrinkled • Obligate aerobic
  • 6. Mycobacterium haemophilum • Short, occasionally curved, gram-positive, nonmotile and strongly acid-fast rods. • Nonpigmented and rough to smooth colonies. • Is an aerobic fastidious organism that grows best at 30–32°C and is a slow-growing organism first identified in 1978 • Growth also depends on the presence of iron or haemin, which is a unique feature. Because of this requirement, it will not grow with standard isolation techniques for other mycobacteria
  • 7.
  • 8.
  • 9.