2. Introduction
• Immunotherapy is used to:
Stop or slow cancer cell growth
Stop cancer cells from spreading to other parts of the body
Be better at killing cancer cells
• Activates or suppresses the immune system
• Monoclonal antibodies are the most traditional form of
immunotherapy
• Types of immunotherapy
3. Monoclonal Antibody
• Immune checkpoint inhibitors to treat breast cancer are:
Tecentriq (chemical name: Atezolizumab)- triple-negative breast cancer
Chemotherapy medicine –Abraxane
• Immunotherapy medicines to treat breast cancer are:
Herceptin (chemical name: trastuzumab)
Perjeta (chemical name: pertuzumab)
Kadcyla (chemical name: T - DM1)
4. Mechanism
• HER2-positive breast cancer by targeting the HER2 receptors on breast
cancer cells
• In addition to blocking HER2 receptors, these medicines can also help fight
breast cancer
• The immune system to destroy cancer cells
• It is called “immune targeted therapies”
• Monoclonal antibodies can also interferes with the following:-
• cell signalling
• blocks cell growth
• communication of tumor cells