2. According to WHO packaging:
‘The Collection of different components which surrounds
the pharmaceutical product from the time of production
until its use’
Container designed for stable pharmaceutical product
Functions of packaging:
Product Identification
Product Protection
Facilitates the product usage
Product Promotion
Introduction
3. Pharmaceutical Packaging
Feeding unit
Appropriate amount of fill
Blister machine
Thermoformable foil web using temperature and pressure
Foil web: Polyvinyl chloride, Polyethylene, Polystyrene
Sealing machine
Aluminium or plastic foil cover
Cuts into individual packages
4. Types of Package
Primary
•Direct contact with the formulation
•Protect from environmental, chemical & mechanical
Secondary
•Provide information about drug product
•Protection from tough handling during transportation
Tertiary
•Outer package of secondary packaging
•Bulk handling & shipping
5. Types of Packaging Materials
Packaging Material
Glass
Borocilicate
glass
Treated
soda lime
glass
Regular
soda lime
glass
Non
Parenteral
glass
Coloured
glass
Metal
Aluminum
Iron
Lead
Rubber
Butyl
rubber
Nitrile
rubber
Chloroprene
rubber
Silicon
rubber
Plastic
Thermoplastic
Thermosetting
6. Case Study
Coartem® dispersible prescription medication
Treat acute malaria infections
Poor comprehension about the usage
Healthcare Compliance Packaging Council
Europe Compliance Pack Award, 2009
Innovation in Malaria Drug Packaging
7. Case Study
Envoid was the first FDA approved oral
contraceptive
David P. Wagner ,1964 invented compact-
shaped dial packs
Patent for medication dispensing means
Memory aid packaging design
Ortho dial pack circular design and a
rectangular calendar design
Oral Contraceptive Pills
Calendar Glass
Dial pack
8. Advancements in Packaging
Temperature indicating labels
Near-field communication (NFC)
Counting packaging
Light up packaging
Unit dosing
Fingerprint authentication packaging
9. Regulatory Aspect
21 Code of Federal Regulations Part 211
Subpart G
Good record keeping
Cut labeling
Controls for drug labeling operations
Packaging for over-the-counter drugs
Finishing operations
Chemical Assessment Biocompatibility
Compatibility
Physiochemical
properties
Regulatory
Parameters
10. Conclusion
Regular packaging materials ensures the proper delivery
The different types of packaging is important for stability
Packaging with appropriate standards for safety
Advancements in packaging technology is vital
Manufacturer should ensure complies with the regulation