IMMUNOLOGY-basics.pdf
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This document provides an overview of immunology and the basics of the immune system. It discusses Nobel Prizes awarded for immunological research and examples of major pathogens like viruses, fungi, parasites, and bacteria that cause human disease. It also summarizes key topics in immunology including hematopoiesis, phagocytosis, inflammation, antigen processing and presentation, B-cell and T-cell activation and maturation, hypersensitivity reactions, and other aspects of immunology like vaccines, clinical applications, and techniques.
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![Wood engraving of Louis Pasteur watching Joseph Meister receive the
rabies vaccine. [Source: From Harper’s Weekly 29:836; courtesy of the
National Library of Medicine.]
28-09-2022 2](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
SAR of Medicinal Chemistry 1st by dk.pdf
In this presentation include the prototype drug SAR on thus or with their examples .
Syllabus of Second Year B. Pharmacy
2019 PATTERN.
Phenomics assisted breeding in crop improvement
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...Advanced-Concepts-Team
Presentation in the Science Coffee of the Advanced Concepts Team of the European Space Agency on the 07.06.2024.
Speaker: Diego Blas (IFAE/ICREA)
Title: Gravitational wave detection with orbital motion of Moon and artificial
Abstract:
In this talk I will describe some recent ideas to find gravitational waves from supermassive black holes or of primordial origin by studying their secular effect on the orbital motion of the Moon or satellites that are laser ranged.Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
The pygmy halfbeak Dermogenys colletei, is known for its viviparous nature, this presents an intriguing case of relatively low fecundity, raising questions about potential compensatory reproductive strategies employed by this species. Our study delves into the examination of fecundity and the Gonadosomatic Index (GSI) in the Pygmy Halfbeak, D. colletei (Meisner, 2001), an intriguing viviparous fish indigenous to Sarawak, Borneo. We hypothesize that the Pygmy halfbeak, D. colletei, may exhibit unique reproductive adaptations to offset its low fecundity, thus enhancing its survival and fitness. To address this, we conducted a comprehensive study utilizing 28 mature female specimens of D. colletei, carefully measuring fecundity and GSI to shed light on the reproductive adaptations of this species. Our findings reveal that D. colletei indeed exhibits low fecundity, with a mean of 16.76 ± 2.01, and a mean GSI of 12.83 ± 1.27, providing crucial insights into the reproductive mechanisms at play in this species. These results underscore the existence of unique reproductive strategies in D. colletei, enabling its adaptation and persistence in Borneo's diverse aquatic ecosystems, and call for further ecological research to elucidate these mechanisms. This study lends to a better understanding of viviparous fish in Borneo and contributes to the broader field of aquatic ecology, enhancing our knowledge of species adaptations to unique ecological challenges.
20240520 Planning a Circuit Simulator in JavaScript.pptx
Evaporation step counter work. I have done a physical experiment.
(Work in progress.)
Thornton ESPP slides UK WW Network 4_6_24.pdf
ESPP presentation to EU Waste Water Network, 4th June 2024 “EU policies driving nutrient removal and recycling
and the revised UWWTD (Urban Waste Water Treatment Directive)”
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
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Compexometric titration/Chelatorphy titration/chelating titration
Classification
Metal ion ion indicators
Masking and demasking reagents
Estimation of Magnisium sulphate
Calcium gluconate
Complexometric Titration/ chelatometry titration/chelating titration, introduction, Types-
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2.Back Titration
3.Replacement Titration
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Masking agent, Demasking agents
formation of complex
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Instrumental Techniques-Photometry
Potentiometry
Miscellaneous methods.
Complex titration with EDTA.
Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
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Slides from talk:
Aleš Zamuda: Randomised Optimisation Algorithms in DAPHNE .
Austrian-Slovenian HPC Meeting 2024 – ASHPC24, Seeblickhotel Grundlsee in Austria, 10–13 June 2024
https://ashpc.eu/
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IMMUNOLOGY-basics.pdf
- 1. Immunology: The Basics Mahuya Sengupta Associate Professor Department of Biotechnology, Assam University, Silchar
- 2. Wood engraving of Louis Pasteur watching Joseph Meister receive the rabies vaccine. [Source: From Harper’s Weekly 29:836; courtesy of the National Library of Medicine.] 28-09-2022 2
- 3. Nobel Prizes for immunologic research 28-09-2022 3
- 4. Virus: Rotavirus Fungus: Candida albicans Parasite: Filaria Bacterium: Mycobacterium tuberculosis Pathogens representing the major categories of microorganisms causing human disease. (a) Viruses: Transmission electron micrograph of rotavirus, a major cause of infant diarrhea. Rotavirus accounts for approximately 1 million infant deaths per year in developing countries and hospitalization of about 50,000 infants per year in the United States. (b) Fungi: Candida albicans, a yeast inhabiting human mouth, throat, intestines, and genitourinary tract; C. albicans commonly causes an oral rash (thrush) or vaginitis in immunosuppressed individuals or in those taking antibiotics that kill normal bacterial flora. (c) Parasites: The larval form of filaria, a parasitic worm, being attacked by macrophages. Approximately 120 million persons worldwide have some form of filariasis. (d) Bacteria: Mycobacterium tuberculosis, the bacterium that causes tuberculosis, being ingested by a human macrophage. [(a) Dr. Gary Gaugler/Getty Images; (b) SPL/Photo Researchers; (c) Oliver Meckes/Nicole Ottawa/Eye of Science/ Photo Researchers; (d) Max Planck Institute for Infection Biology/Dr. Volker Brinkmann.] PATHOGENS 28-09-2022 4
- 5. Major groups of human pathogens Specific examples Disease Viruses Poliovirus Poliomyelitis (Polio) Variola Virus Smallpox Human Immunodefi ciency Virus AIDS Rubeola Virus Measles Fungi Candida albicans Candidiasis (Thrush) Tinea corporis Ringworm Cryptococcus neoformans Cryptococcal meningitis Parasites Plasmodium species Malaria Leishmania major Leishmaniasis Entamoeba histolytica Amoebic colitis Bacteria Mycobacterium tuberculosis Tuberculosis Bordetella pertussis Whooping cough (pertussis) Vibrio cholerae Cholera Borrelia burgdorferi Lyme disease 28-09-2022 5
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- 8. Generation of diversity and clonal selection and expansion PHAGOCYTOSIS Immunologic memory 28-09-2022 8
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- 11. Antigen processing and presentation 28-09-2022 11
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- 30. B-cell and T-cell: Activation and Maturation 28-09-2022 30
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- 36. Type-I reaction: allergy Type-II: Erythroblastosis fetalis 28-09-2022 36
- 37. Type-III: Arthus reaction Type- IV: DTH 28-09-2022 37
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- 39. Other aspects of Immunology • Vaccines • Clinical Immunology • Response to infectious diseases • AIDS and other immuno-deficiencies • Cancer Immunology • Immunological Tolerance • Immunological Techniques • Transplantation Immunology • Immunotoxicology 28-09-2022 39
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