This document summarizes the history and current state of immunizations/vaccinations. It discusses how immunizations began with Edward Jenner's smallpox vaccine in 1796. Today, vaccines are recommended from birth through adulthood to prevent various diseases. However, some parents choose not to vaccinate their children due to safety concerns or religious beliefs. While studies generally support that vaccines are safe and their benefits outweigh risks, ongoing research continues to examine both sides of this controversial issue.