for b.pharma students

1. W
E
L
C
O
M
E

2. AS THERAPEUTIC AGENTS
SEMINAR BY
k.garlic reddy(B.Pharm)
UNDER THE GUIDENCE OF
K. YALLA REDDY M.pharm.
JAGAN’S COLLGE OF PHARMACY
• NELLORE

3. CONTENTS
• DEFINITION
• CLASSIFICATION
ANTIOXIDANTS
POLYUNSATURATED FATTY ACIDS
PREBIOTICS
PROBIOTIS
DIETARY FIBRES
• EXAMPLES:SPIRULINA,ROYAL
JELLY,SOYA, GARLIC

4. DEFINITION
• Nutraceuticals are the chemical substances which can be considered as the
food or its part, in addition to its normal nutritional value provides health
benefits including prevention of disease or promotion of health.

5. APPLICATIONS
• The major diseases for the prevention or treatment of
which nutraceuticals have been associated are heart
failure, cancer, hypertension and diabetis.
• The other diseases which related with role of
nutraceuticals are osteoporosis, arthritis and neural tube
defects. Certain dietary habit can enhance cancer risk.
• Designing a proper food to maintain proper health has
gained recognition and acceptance world wide.
• Due to this , the food industry in many countries is
modifying their products as responsible for consumer
goods.

6. CLASSIFICATION
• The food substances used as nutraceuticals
contain
Antioxidants
Polyunsaturated fatty acids
Prebiotics
probiotics
Omega-3-fatty acids
Dietary fibres

7. ANTIOXIDANTS
• Antioxidant nutraceuticals contain vit-C, E,A and
carotene. They are present in some fixed oils , fruits,
vegetables, and fishes.
• Antioxidants present in such food materials which
prevent the formation of free radicals or scavenging
activity.

8. ANTIOXIDANTS
• Some of the naturally antioxidants are which could be
therapeutic use are super oxide dismutase, tocopherol,
ascorbic acid, adenosine, transferin, lactoferin,
glutathione, carotenoids and their plant pigments.
• The oxidation of LDL cholesterol increases the chance
of atherosclerosis,
• Tocopherols reduce platlet role in thrombous formation,
• Various plants like amla, myrobalan, lemon, prevent
oxidation and scavenging of oxygen free radicals.
• Beta carotene and vit-A shown antioxidant effect.

9. POLYUNSATURARED FATTY
ACIDS
• These are present in various vegetable oils and
marine animals . These source include safflower,
corn oil, musturd oil, soyabean oil, they help
reduce cholesterol formation.
• Vegetable oil contain PUFA belonging to
Linolenic group.
• Some marine fishes contain PUFA belonging to
omega-6 type, omega-3 type.
• These reduce thromboxane formation and hence
useful as preventive measures of atherosclerosis.

11. PROBIOTICS
• These are living microorganisms, which when taken
with or without food,
• It improve the intestinal microbial balance and in turn
functioning of large intestine.
• Probiotics include Bifidobacterium and lactobacilli
species like L.Acidophilus.
• These microorganism exert their effects by producing
substances and conditions which inhibit the growth of
harmful bacteria in the large intesine.
• The dairy products like sour milk, yoghurt containg
probiotics.

12. Probiotics

15. PREBIOTICS
• Prebiotics are the food substances which reach to colon
in intact form, without getting depleted by gastric pH.
• These are nutraceuticals which promote the flourishing
the probiotics.
• Before reaching the colonic region , the probiotic
microorganisms have to survive against the digestive
enzymes and acids in the upper gut.
• To overcome this problem , nutraceuticals in the form
of probiotics available.
• Example: inulin polyfructose obatained from raw
chicory.

17. DIETARY FIBRES
• These play a critical role in maintenance of
health. They can be defined as such parts of plant
stems, leaves and seeds. Which human body
cannot digest and absorb.
• High fibre intake gives variety benefits to human
body. Dietary fibres are generally categorized into
two groups water soluble and water insoluble.
• Insoluble fibres mainly helps in bulking of stools
and their quick passage through digestive canal.
• Soluble fibres dissolves in water and forms that
binds the stool.

18. DIETARY FIBRES
• Insoluble fibres mainly present in brown rice ,
banana, cassoval, vegetables, whole grain ,
cereals, oats, barly, sorghum.
• Soluble fibres are present in oats, dried beans,
legumes, chocory etc.

19. OMEGA-3-FATTY ACIDS
• The current trends in biodrugs indicate the
commercial utility of omege-3-fatty acids ,
spirulina, soya, garlic, and royal jelly.
• Omega-3-fatty acids are Eicosapantaenoic acid
and docosahexanoic acid DHA. They are
polyunsaturated fatty acids mainly in the marine
groups.
• They are found in the cold water fishes, cod,
salmon, tuna, sardines, blue fish, mackerel and
harring.

21. SPIRULINA
• Bilogical source: it is the blue green algae Spirulina
platensis, Spirulina maxima [family:Oscillatoraceae]
• Chemical constituents: proteins,
lipids, essential fatty acids, oleic,
lioleic, palmitic, palmitoleic,
heptadecanoic acids.
Uses: immunostimulant
cancer treatment
influenza virus,
mumps and
measle virus.

22. ROYAL JELLY
• Bilogical source: it is yellowish, traslucent highly
viscous substance produced by fermentation of
the secretion of the salivary glands of the worker
bees “Apis mellifera” family Apidae
• Chemical constituents: rich source of Vit-
A,B1,B2, B6, B12, pantothenic acid, nicotinic
acid, Vit-C
• Uses:health tonic and food supplement.

23. SOYA
• Bilogical source:it is obtained from the soyabean “Glycine
max” family: Fabaceae
• Chemical constituents: it contain carbohydrate , fats ,
vitamins, and minerals high calcium content,iron and
potassium.isoflavone, genistein and daidzein.
• Uses:
• Treatment of coronary heart disease
lower blood cholesterol
Carcinomes
osteoporosis

24. GARLIC
• Bilogical source:It is obtained
from the bulbs of “Allium
sativum” family:Liliaceae.
• Chemical constituents:
carbohydrates, proteins, sulphur
based compound allin and
allicin.
• Uses:antibiotic, amoebic
dysentery, antioxidant and
atherosclerosis.

25. CONCLUSION
• “Prevention & treatment
with Nutraceuticals is a
powerful instrument in
maintaining health & to
act against nutritionally
induced acute & chronic
disease, there by
promoting the optimal
health, longevity &
quality of life.”

26. Only education makes us to understand, it enlightens everyone’s life.

28. Psoralea fruit[bavchi]
• Telugu: Bhavanchi-Vittulu,
• G.S:Srilanka and India
• Macroscopical charecters:

29. Chemical constituents

30. Uses

31. uses

32. Uses