Ibogaine therapy uses different forms and dosing regimens of ibogaine to treat substance abuse disorders and other conditions. The forms include the root bark of Tabernanthe iboga, total alkaloid extracts, and purified ibogaine hydrochloride. Dosing can involve a single high dose, multiple escalating or de-escalating doses, or linear dosing schedules. Effective single doses typically range from 10-22 mg/kg, most often 15-20 mg/kg, but the appropriate dosing depends on individual patient factors and treatment goals.

1. Ibogaine Therapy: Forms and Dose Regimens Howard S. Lotsof, B.F.A., C.M.A. President Dora Weiner Foundation Staten Island, NY http://www.doraweiner.org

3. Tabernanthe iboga shrub

4. Roots contain ibogaine

5. Total Alkaloid Extract Large piece 2cm x 2cm, approx 4 grams Estimate 15% ibogaine Courtesy Sara Glatt

6. Ibogaine HCl 99.4% purity

14. All doses are representative. Doses, including single administration doses are determined on a patient by patient basis. The graphs of dose regimens and information that follow should not be used by persons without experience to self-administer or administer to others any dose of ibogaine or total alkaloid extract of Tabernanthe iboga .

15. Single dose regimens usually fall between 10mg/kg and 22mg/kg depending on type of therapy offered: opioid dependence, stimulant dependence, psychospiritual, etc. Most doses fall in the 15mg/kg - 20mg/kg dose range to reach full therapeutic effects.

23. All doses and dose regimens shown or discussed are representative and are not indicated to be provided to any other patient or subject. All doses and dose regimens are made on a patient by patient basis upon knowledge and prior art.