Hypertension is the most common cardiovascular risk factor worldwide, affecting one third of the global population. The current definition of hypertension as a blood pressure over 140/90 mmHg measured during multiple clinic visits is insufficient because blood pressure is a continuously changing variable that can be influenced by daily activities and stress. An updated definition is needed that incorporates measurements from home blood pressure monitoring and ambulatory blood pressure monitoring to better identify true hypertension versus transient high readings and better predict cardiovascular outcomes based on variability.