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AMBULATORYBLOODPRESSURE MONITORING
[ABPM]
BY
DR.VASUDEVA CHETTY.P
SENIOR RESIDENT
DEPT. OF CARDIOLOGY
SVIMS,TIRUPATI.
CAPSULE ON INVESTIGATION
INTRODUCTION
ABPM , 50 YRS BACK MODERN
BP VARIABILITY
MEASURES OF BP VARIABILITY,INSTABILITY,REACTIVITY
 High BP is a trait as opposed to a specific disease and represents a
quantitative rather than a qualitative deviation from the norm.
 Any definition of hypertension is therefore arbitrary.
 Thus a practical definition of hypertension is ‘the level of BP at
which the benefits of treatment outweigh the costs and hazards’.
DAVIDSON’S PRINCIPLES AND PRACTICE OF MEDICINE 21ST ED
True BP vs Surrogate
 Any clinical measurement of blood pressure may be regarded as a
surrogate measure for the “TRUE” blood pressure of the patient,
which may be defined as the mean level over prolonged periods.
 Two techniques have been developed to improve the estimate of
true blood pressure — ambulatory monitoring and home monitoring
(or self-monitoring).
ABPM
 Ambulatory blood pressure (ABP)
monitoring involves measuring blood
pressure (BP) at regular intervals
(usually every 20–30 minutes) over a
24 hour period while patients
undergo normal daily activities,
including sleep.
 The portable monitor is worn on a belt
connected to a standard cuff on the
upper arm .
 When complete, the device is connected
to a computer that prepares a report of
the 24 hour, day time, night time, and
sleep and awake (if recorded) average
systolic and diastolic BP and heart rate.
ABPM – measuring Method
 Ambulatory BP monitors use cuff oscillometry.
 The cuff is inflated until the pressure occludes flow within the brachial
artery. As the pressure is released, blood begins to flow causing fluctuations
(oscillations) in the arterial wall that are detected by the monitor. These
oscillations increase in intensity then diminish and cease when blood is
flowing normally.
 The monitor defines the maximal oscillations as mean arterial BP and then
uses an algorithm to calculate systolic and diastolic BP.
ANALYSIS OF ABPM
Reference ‘normal’ ABP values for nonpregnant adults are:
 24 hour average <115/75 mmHg (hypertension threshold
130/80 mmHg)
 Day time (awake) <120/80 mmHg (hypertension threshold
135/85 mmHg)
 Night time (asleep) <105/65 mmHg (hypertension threshold
120/75 mmHg).
ABPM – Diagnostic Thresholds
Category 24hr
systolic/diastolic
(mm Hg)
Daytime
(mm Hg)
Nighttime
(mm Hg)
NORMAL <115/75 <120/80 <105/65
HTN >130/80 >135/85 >120/75
 Ambulatory BP values above ‘normal’ and below thresholds for
hypertension are considered ‘high normal’.
 Night time (sleeping) average systolic and diastolic BP should both
be at least 10% lower than day time (awake) average.
 Blood pressure load (percentage of time that BP readings exceed
hypertension threshold during 24 hours) should be <20%.
Indications for ABPM
 Suspected white-coat hypertension (including in pregnancy)
 Suspected masked hypertension (untreated subject with normal
clinic BP and elevated ABP)
 Suspected nocturnal hypertension or no night time reduction in BP
(dipping)
 Hypertension despite appropriate treatment
 Patients with a high risk of future cardiovascular events (even if
clinic BP is normal)
 Suspected episodic hypertension.
Ambulatory BP monitoring may also be useful for:
 Titrating antihypertensive therapy
 Borderline hypertension
 Hypertension detected early in pregnancy
 Suspected or confirmed sleep apnoea
 Syncope or other symptoms suggesting orthostatic Hypotension,
where this cannot be demonstrated in the clinic.
CLASSIFICATION BASED ON ABPM
WHITE COAT HYPERTENSION
 White-coat hypertension is defined as a clinic blood pressure of 140/90
mm Hg or higher on at least three occasions, with at least two sets of
measurements of less than 140/90 mm Hg in non-clinic settings, plus the
absence of target-organ damage.
MASKED HYPERTENSION
 Defined as a normal clinic blood pressure and a high ambulatory
blood pressure.
 This condition is the reverse of white-coat hypertension.
 The clinic blood pressure of patients with masked hypertension may
underestimate the risk of cardiovascular events.
ABPM --PREDICTING CLINICAL OUTCOMES
Global Leading Risks for Death
Systolic blood
pressure > 115
mmHg
Global Burden of Disease Study 2010 , Lancet 2012; 380: 2224–60
India- Soon Heading Towards Being
Hypertension Capital
60.4
107.3
57.8
106.2
0
20
40
60
80
100
120
2000 2025
No.ofpeoplewithhypertension
inIndia(millions)
Men Women
Lancet 2005;365:217-23; JHH 2004;18:73-8J Assoc Physicians India 2007;55:323-4
At least 1 out of every 5 adult Indians has hypertension
Age > 20 yrs
Hypertension is responsible for 57% of all stroke deaths
and 24% of all CHD deaths in India
ABPM --ENDORSEMENT
NICE GUIDELINES 2011
CONCLUSION
 Ambulatory monitoring can be regarded as the gold standard for
the prediction of risk related to blood pressure, since prognostic
studies have shown that it predicts clinical outcome better than
conventional blood-pressure measurements.
 Therefore, a good case can be made for using this technique in all
patients in whom hypertension has been newly diagnosed by
means of clinic blood-pressure measurements.
Ambulatory blood pressure monitoring [abpm]

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Ambulatory blood pressure monitoring [abpm]

  • 1. AMBULATORYBLOODPRESSURE MONITORING [ABPM] BY DR.VASUDEVA CHETTY.P SENIOR RESIDENT DEPT. OF CARDIOLOGY SVIMS,TIRUPATI. CAPSULE ON INVESTIGATION
  • 3.
  • 4. ABPM , 50 YRS BACK MODERN
  • 5.
  • 7. MEASURES OF BP VARIABILITY,INSTABILITY,REACTIVITY
  • 8.
  • 9.  High BP is a trait as opposed to a specific disease and represents a quantitative rather than a qualitative deviation from the norm.  Any definition of hypertension is therefore arbitrary.  Thus a practical definition of hypertension is ‘the level of BP at which the benefits of treatment outweigh the costs and hazards’. DAVIDSON’S PRINCIPLES AND PRACTICE OF MEDICINE 21ST ED
  • 10. True BP vs Surrogate  Any clinical measurement of blood pressure may be regarded as a surrogate measure for the “TRUE” blood pressure of the patient, which may be defined as the mean level over prolonged periods.  Two techniques have been developed to improve the estimate of true blood pressure — ambulatory monitoring and home monitoring (or self-monitoring).
  • 11. ABPM  Ambulatory blood pressure (ABP) monitoring involves measuring blood pressure (BP) at regular intervals (usually every 20–30 minutes) over a 24 hour period while patients undergo normal daily activities, including sleep.
  • 12.  The portable monitor is worn on a belt connected to a standard cuff on the upper arm .  When complete, the device is connected to a computer that prepares a report of the 24 hour, day time, night time, and sleep and awake (if recorded) average systolic and diastolic BP and heart rate.
  • 13. ABPM – measuring Method  Ambulatory BP monitors use cuff oscillometry.  The cuff is inflated until the pressure occludes flow within the brachial artery. As the pressure is released, blood begins to flow causing fluctuations (oscillations) in the arterial wall that are detected by the monitor. These oscillations increase in intensity then diminish and cease when blood is flowing normally.  The monitor defines the maximal oscillations as mean arterial BP and then uses an algorithm to calculate systolic and diastolic BP.
  • 14.
  • 16. Reference ‘normal’ ABP values for nonpregnant adults are:  24 hour average <115/75 mmHg (hypertension threshold 130/80 mmHg)  Day time (awake) <120/80 mmHg (hypertension threshold 135/85 mmHg)  Night time (asleep) <105/65 mmHg (hypertension threshold 120/75 mmHg).
  • 17. ABPM – Diagnostic Thresholds Category 24hr systolic/diastolic (mm Hg) Daytime (mm Hg) Nighttime (mm Hg) NORMAL <115/75 <120/80 <105/65 HTN >130/80 >135/85 >120/75
  • 18.  Ambulatory BP values above ‘normal’ and below thresholds for hypertension are considered ‘high normal’.  Night time (sleeping) average systolic and diastolic BP should both be at least 10% lower than day time (awake) average.  Blood pressure load (percentage of time that BP readings exceed hypertension threshold during 24 hours) should be <20%.
  • 19.
  • 20.
  • 21. Indications for ABPM  Suspected white-coat hypertension (including in pregnancy)  Suspected masked hypertension (untreated subject with normal clinic BP and elevated ABP)  Suspected nocturnal hypertension or no night time reduction in BP (dipping)  Hypertension despite appropriate treatment  Patients with a high risk of future cardiovascular events (even if clinic BP is normal)  Suspected episodic hypertension.
  • 22. Ambulatory BP monitoring may also be useful for:  Titrating antihypertensive therapy  Borderline hypertension  Hypertension detected early in pregnancy  Suspected or confirmed sleep apnoea  Syncope or other symptoms suggesting orthostatic Hypotension, where this cannot be demonstrated in the clinic.
  • 24. WHITE COAT HYPERTENSION  White-coat hypertension is defined as a clinic blood pressure of 140/90 mm Hg or higher on at least three occasions, with at least two sets of measurements of less than 140/90 mm Hg in non-clinic settings, plus the absence of target-organ damage.
  • 25. MASKED HYPERTENSION  Defined as a normal clinic blood pressure and a high ambulatory blood pressure.  This condition is the reverse of white-coat hypertension.  The clinic blood pressure of patients with masked hypertension may underestimate the risk of cardiovascular events.
  • 27. Global Leading Risks for Death Systolic blood pressure > 115 mmHg Global Burden of Disease Study 2010 , Lancet 2012; 380: 2224–60
  • 28. India- Soon Heading Towards Being Hypertension Capital 60.4 107.3 57.8 106.2 0 20 40 60 80 100 120 2000 2025 No.ofpeoplewithhypertension inIndia(millions) Men Women Lancet 2005;365:217-23; JHH 2004;18:73-8J Assoc Physicians India 2007;55:323-4 At least 1 out of every 5 adult Indians has hypertension Age > 20 yrs Hypertension is responsible for 57% of all stroke deaths and 24% of all CHD deaths in India
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 37.
  • 38.
  • 39.
  • 40. CONCLUSION  Ambulatory monitoring can be regarded as the gold standard for the prediction of risk related to blood pressure, since prognostic studies have shown that it predicts clinical outcome better than conventional blood-pressure measurements.  Therefore, a good case can be made for using this technique in all patients in whom hypertension has been newly diagnosed by means of clinic blood-pressure measurements.