The chapter discusses the uneven nature of economic development globally. It begins by defining economic development and explaining different theories for why some regions are more developed than others. The key aspects covered include the structure of economies, international trade, development models, and pathways to regional development. Globalization has meant that local and regional economic development is more influenced by external forces. Overall, the chapter examines the patterns and processes of economic development worldwide and how this development is spatially uneven across different regions.