3. HUMAN GENOME PROJECT
The Human Genome Project (HGP) was an international
scientific research project with the goal of determining the
base pairs that make up human DNA, and of identifying,
mapping and sequencing all of the genes of the human
genome from both a physical and a functional stand point.
The Human Genome Project identified the full set of human
genes, sequenced them all, and identified some of the alleles,
particularly those that can cause disease when they get
mutated. Genes can be mapped relative to physical features
of the chromosome, or relative to other genes.
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4. History of human genome project.
The Human Genome Project was a 13-year-long publicly
funded project initiated in 1990 with the objective of
determining the DNA sequence of the
entire euchromatic human genome within 15 years.
This project cost many money about estimated $2.7 billion
to complete.
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5. Goals of the human genome
project
Optimization of the data analysis.
Sequencing the entire genome.
Identification of the complete human genome.
Creating genome sequence databases to store the data.
Taking care of the legal, ethical and social issues that
the project may pose.
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6. HGP
The Human Genome Project (HGP) was one of the
great feats of exploration in history. Rather than an
outward exploration of the planet or the cosmos.
the HGP was an inward voyage of discovery led by an
international team of researchers looking to sequence
and map all of the genes together known as the
genome of members of our species, Homo sapiens.
Beginning on October 1, 1990 and completed in April
2003
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7. HGP
It is generally agreed that the overall goal of the
Human Genome Initiative is to acquire fundamental
information needed to further our basic scientific
understanding of human genetics and of the role of
various genes in health and disease . As refined
through the discussions over the last half of the 1980's
and defined in the NRC report, the Human Genome
Initiative has several interrelated goals.
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8. HGP
Construction of a high-resolution genetic map of the
human genome;
Production of a variety of physical maps of all human
chromosomes and DNA of selected model organisms, with
emphasis on maps that make the DNA accessible to
investigators for further analysis;
Determination of the complete sequence of human DNA
and of the DNA of selected model organisms;
Development of capabilities for collecting, storing,
distributing, and analyzing the data produced;
Creation of appropriate technologies necessary to achieve
these objectives.
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9. RESULTS
The project showed that humans have 99.9% identical
genomes, and it set the stage for developing a catalog
of human genes and beginning to understand the
complex choreography involved in gene expression.
THANK YOU …
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