Hemophilia is a recessive trait located on the X chromosome. If a homozygous normal female marries a normal male, their children would have the following phenotypes: normal females and normal males. Hemophilia is an X-linked recessive trait, so a female who inherits the gene but does not express the trait can pass it on to her sons. In this case, with both parents being normal, all their children would be normal.

1. Hemophilia is a recessive trait. The dominant trait is normal blood dotting A gene that can cause
hemophilia is located on the X chromosome. If a homozygous normal female marries a normal
male, they children might have which of the following phenotypes: Select one: a. normal
females, hemophiliac females, and hemophiliac males. b. normal females, hemophiliac females,
normal males, and hemophiliac males. c. normal females and hemophiliac males d. normal
females and normal mates. e. normal females, normal males or hemophiliac males.
Solution
In X - linked recessive inheritance males are more prone to disease because they carry the
disease trait. If the affected offspring’s mother has brother or father containing the same trait
then the mother pass the trait to her offspring. The affected males produce unaffected daughters
who can produce 50% affected sons. Hemophilia is the example of X - linked recessive trait.
When a homozygous normal female marries to a normal male the offspring produced are normal
females and normal males. Option d is correct.