This chapter discusses issuing and distributing pharmaceuticals. It defines drug distribution as receiving drugs from suppliers and moving them safely to healthcare facilities. The drug distribution cycle is described as including port clearing, receipt and inspection, inventory control, storage, requisitioning supplies, delivery, dispensing to patients, and consumption reporting. Factors considered in designing an effective distribution system include geographic coverage, number of levels, storage locations, transport options, and inventory management. Proper procedures for issuing pharmaceuticals within health centers and hospitals and to health posts are also outlined.
Purchasing and Inventory control in drug store
by Mrs. Anjua Parkhe and Mrs. Priyanka Kalamkar
Assistant Professor
Sraaswathi Vidya Bhavans College Of Pharmacy, Dombivli
Purchasing and Inventory control in drug store
by Mrs. Anjua Parkhe and Mrs. Priyanka Kalamkar
Assistant Professor
Sraaswathi Vidya Bhavans College Of Pharmacy, Dombivli
Expt. 13 Calculation of pharmacokinetic parameters from a given dataVISHALJADHAV100
Objective
Pharmacokinetics (PKs) and Clinical Pharmacokinetics
Plasma Drug Concentration-Time Profile
Peak Plasma Concentration (Cmax)
Time of Peak Concentration (tmax)
Area Under the Curve (AUC)
Bioavailability (BA)
Volume of Distribution (Vd)
Half-Life (t1/2)
Clearance (CL)
Loading and Maintenance Dose
Result and interpretation
Definition, contents of hospital formulary, Differentiation of hospital formulary and Drug list, preparation and revision, and addition and deletion of a drug from hospital formulary.
Drug distribution is defined as, "Physical transfer of drugs from storage area in the hospital to the patient's bedside".
This involves two types of drug distribution. They are:
In-patient distribution
Out-patient distribution
The drug distribution to the in patient department can be carried out from the out patient dispensing area.
The pharmacists involved in dispensing the drugs for out patient can dispense drugs for in patients too.
The pharmacist employed for drug distribution to the in patient wards should be well skilled and qualified staff.
Out patient refers to the patients not occupying beds in hospital or in clinics, health centers and other places where out patients usually go for health care.
No medicaments should be issued without the prescription.
After the issue has been made the quantities supplied must be recorded.
In short form the out patient department was called as OPD.
CLASSIFICATION OF PATIENTS
EMERGENCY
TERTIARY CARE
PRIMARY CARE
AMBULATORY.
Expt. 13 Calculation of pharmacokinetic parameters from a given dataVISHALJADHAV100
Objective
Pharmacokinetics (PKs) and Clinical Pharmacokinetics
Plasma Drug Concentration-Time Profile
Peak Plasma Concentration (Cmax)
Time of Peak Concentration (tmax)
Area Under the Curve (AUC)
Bioavailability (BA)
Volume of Distribution (Vd)
Half-Life (t1/2)
Clearance (CL)
Loading and Maintenance Dose
Result and interpretation
Definition, contents of hospital formulary, Differentiation of hospital formulary and Drug list, preparation and revision, and addition and deletion of a drug from hospital formulary.
Drug distribution is defined as, "Physical transfer of drugs from storage area in the hospital to the patient's bedside".
This involves two types of drug distribution. They are:
In-patient distribution
Out-patient distribution
The drug distribution to the in patient department can be carried out from the out patient dispensing area.
The pharmacists involved in dispensing the drugs for out patient can dispense drugs for in patients too.
The pharmacist employed for drug distribution to the in patient wards should be well skilled and qualified staff.
Out patient refers to the patients not occupying beds in hospital or in clinics, health centers and other places where out patients usually go for health care.
No medicaments should be issued without the prescription.
After the issue has been made the quantities supplied must be recorded.
In short form the out patient department was called as OPD.
CLASSIFICATION OF PATIENTS
EMERGENCY
TERTIARY CARE
PRIMARY CARE
AMBULATORY.
This document is about the use and misuse of controlled substances and the role and responsibilities of the pharmacist in providing these substances. The storage conditions and the drug act about the misuse of the substances.
What is logistics?
Logistics is the process of getting resources, storing them, and moving them to where they need to go.
Logistics systems: are the part of supply chain management that plans, implements, and controls the efficient, effective forward and reverse flow and storage of goods, services and related information between the point of origin and the point of consumption in order to meet customers’ requirements.
Logistics management is an integrating function that coordinates and optimizes all logistics activities as well as integrates logistics activities with other functions, including marketing, sales manufacturing, finance, and information technology.
This presentation contain introduction to Good Distribution Practices Guideline. and Legal GDP requirements put worldwide.
Good distribution practice (GDP) describes the minimum standards that a wholesale distributor must meet to ensure that the quality and integrity of medicines is maintained throughout the supply chain
Each participant in the distribution chain must agree by the relevant requirements in order to retain the original quality of pharmaceutical products.
Each activity in the distribution of pharmaceutical products shall be carried out according to the principles of Good Distribution Practices (GDP) as applicable.
The risks involved are likely to be of a nature comparable to those that are present in the industrial environment, such as mix-ups, adulteration, contamination, cross-contamination, and spurious.
The guideline addresses
Personnel
Quality System
Premises Warehousing and Storage
Documentation
Traceability
Complaints and Returns
Transportation
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
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2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
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Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
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Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
2. LEARNING OBJECTIVES
At end of this session students will able to;
Define and understand drug distribution cycle
know the objective of drug distribution
Describe major elements of distribution system
Know conditions should be considered during issuing
pharmaceutical for different health sectors
2
3. 5.1. PHARMACEUTICAL DISTRIBUTION
CYCLE
Drug distribution is a continuous process of
receiving drugs from the supplier and
moving them safely/securely to the many points
in the health care system at which the drugs will
be dispensed to patients.
Distribution includes
clearing customs,
stock control, and
stock management of delivery to drug
health facilities.
3
4. DISTRIBUTION CYCLE …
Storage and distribution costs are a significant
component of the health budget.
Transportation costs may exceed the value of the
drugs distributed to some locations, especially in
large countries with low population densities.
Reducing these costs can mean that more money
is available for;
drugs purchases and
clinical care.
4
5. DISTRIBUTION CYCLE …
Logistics is the science and art of getting;
The right amounts
Of the right things
To the right place
At the right time.
5
6. DISTRIBUTION CYCLE …
What is the objective of drug distribution?
To provide a steady supply of drugs of ;
the required quality,
in the required quantity,
at the right time, and
in the right place for the delivery of continuous health
services.
A good distribution system is cost effective system. 6
7. DISTRIBUTION CYCLE …
A well-designed and well-managed distribution
system should:
Maintain a constant supply of drugs
Keep drugs in good condition
Minimize drug loses due to spoilage and expiry
Rationalize drug storage points
7
8. DISTRIBUTION CYCLE …
Use available transport as efficiently as possible
Reduce theft and fraud
Provide information for forecasting drug needs
Incorporate a quality assurance program
8
10. DISTRIBUTION CYCLE …
The distribution cycle begins
when drugs are dispatched by the manufacturer
or supplier.
The distribution cycle ends;
when drug consumption information is reported
back to the procurement unit.
10
12. DISTRIBUTION CYCLE …
i. Port-Clearing
Unless the drugs are acquired locally, the
international supplier takes responsibility for it.
port-clearing is the first step in making drug
available for distribution.
Port-clearing involves:
Identifying shipments as soon as they arrive in port
Processing all important documents
Completing any customs requirements
Storing drugs properly until they leave the port
Surveying the shipments for losses and signs of damage
Collecting the drugs as soon as they are cleared
12
13. DISTRIBUTION CYCLE …
ii. Receipt and inspection
When Items first delivered from the port or directly
from a supplier to the store room;
They must be kept separate from the other stock
until the store staff has performed a complete formal
inspection of the supplies.
Inspectors should check for;
damaged and missing items and
for compliance with the contract conditions
concerning:
drug type, quantity, presentation,
packaging, labeling and any special requirements.
13
14. DISTRIBUTION CYCLE …
iii. Inventory control
It is the process of maintaining of stock properly at
all levels and at all times.
Is used for
requisitioning and issuing drugs, for financial
accounting and
preparing the consumption and stock
balance reports necessary for procurement.
Inventory records must be monitored regularly by
supervisors :
to ensure accuracy and
to avoid or detect losses. 14
15. DISTRIBUTION CYCLE …
iv. Storage
Proper location, construction, organization and
maintenance of storage facilities help:
maintain drug quality
minimize theft, and
maintain regular supply to health
facilities.
15
16. DISTRIBUTION CYCLE …
V. Requisition of supplies
Drug supply systems operate under a push or a
pull system.
The forms and procedures for requisition are a
key part of the inventory control system .
They may vary from country to country and from
one level to another within the same country.
The requisition system may be
manual or
computerized,
16
17. DISTRIBUTION CYCLE …
But it should always be designed to simplify
distribution by:
Facilitating inventory control,
Providing an audit trail for tracing the flow of
drugs,
Assisting in financial accounting, and listing
drugs issued.
17
18. DISTRIBUTION CYCLE …
vi. Delivery
Drugs may be delivered by warehouse staff or
collected by health facilities staff.
Transport may involve;
air, water, railway,
Road vehicles or
on- and off-road vehicles, porters, or a combination of
means.
Transportation methods must be carefully selected
& schedule deliveries realistically and
systematically,
to provide punctual and economic service.
18
19. DISTRIBUTION CYCLE …
vii. Dispensing to patients
When the distribution process achieves its
purpose?
drugs reach hospital wards, outpatient clinics, health centers,
or community health workers and
Are appropriately prescribed and dispensed to patients.
When adequate inventory and requisition records
are kept, compiling consumption reports is
straightforward.
19
20. DISTRIBUTION CYCLE …
viii. Consumption reporting
The closing link in the distribution cycle is
the flow of information on consumption and
stock balances back through the distribution
system to the procurement office for use in
quantifying procurement needs.
20
21. 5.2. PHARMACEUTICAL DISTRIBUTION
SYSTEM DESIGN
Designing distribution system or, evaluating and
planning improvements to an existing system,
requires;
Systematic cost-effectiveness analysis and
Operational planning.
Once the system is in place, regular performance
monitoring is needed;
to ensure that the system functions as intended.
21
22. DISTRIBUTION SYSTEM …
Major elements of distribution system
I. system design:
Geographic or population coverage ,
Number of level , in the system ,
Its degree of centralization
II. Delivery:
Collection versus delivery,
Choice of transportation
Vehicles maintenance and delivery schedule.
III. Storage:
selections of items,
building design,
materials handling system.
22
23. DISTRIBUTION SYSTEM …
IV. Information system:
inventory control records and forms,
consumption reports,
information flow.
23
24. DISTRIBUTION SYSTEM …
I. system design:
The basic characteristics of a distribution
system design include:
Its degree of centralization
The number of levels in the system
The geographic or population coverage
24
25. DISTRIBUTION SYSTEM …
In central supply system, drug procurement and
distribution are coordinated at the national level.
Drugs received at the central medical stores (CMS)
are distributed to lower-level warehouses and
onward to the health facilities.
In a decentralized system, the districts or regions
are responsible for receiving, storing and
distributing drugs.
In some cases, the districts or regions may also be
responsible for procurement.
25
26. DISTRIBUTION SYSTEM …
In designing a distribution system or redesigning
an existing system the following important steps
have to be taken:
1. Determine the number of storage levels in the
system.
Factors to consider in determining the number of
storage level are:
Geographical factors,
Population,
availability of storage space,
staffs,
availability and cost of transport,
Political and other resource constraints. 26
27. DISTRIBUTION SYSTEM …
2. Determine the location of storage sites.
3. Decide at which level of the supply system
decisions will be made concerning orders.
4. Fix re-supply interval or frequency of placing
orders.
5. Select a method of distributing drugs to user units.
Select a collection or delivery method for distributing medicines to user
units
27
28. DISTRIBUTION SYSTEM …
6. Select an appropriate method of transport.
7. Determine the amount of inventory to be held at
each level in the system
8. Develop a set of feasible and economical delivery
routes and work out a practical delivery schedule and
appropriate modes of transport to service these
routes;
28
29. DISTRIBUTION SYSTEM …
9. Estimate the operating costs and assess the cost
effectiveness of contracting for storage and transport
at one or more levels
10. Establish a warehouse management system
based on a set of standard operating procedures
29
30. DISTRIBUTION SYSTEM …
Requisition of supplies
An essential decision must be made as to which
levels of the system will order drugs and which, if
any will passively receive drugs distributed from
higher levels.
Drug supply systems may operate under a push or
a pull system.
30
31. DISTRIBUTION SYSTEM …
Model 20:
used for requesting supplies from
suppliers/other sources
Model 19:
used to receiving drugs and supplies from
suppliers/other sources
Model 22:
used to issuing drugs and medical supplies to
the health institutions/dispensing unit within the
health facility.
31
32. DISTRIBUTION SYSTEM …
The two basic alternatives are:
Pull system:
Each level of a system determines what types and
quantities of drugs are needed and places orders
with the supply source.
It is sometimes known as independent demand
or a requisition system.
32
33. DISTRIBUTION SYSTEM …
Conditions favorable to a pull system of inventory
management include;
Lower-level staff are competent in assessing needs and
managing inventory.
Sufficient supplies are available at supply source to
meet all program needs.
A large range of products is being handled.
Field-staff members are regularly supervised, and
performance is monitored.
Good data are available to decision makers.
33
34. DISTRIBUTION SYSTEM …
Push system:
Supply sources at some level in the system
determine;
what types and
quantities of drugs will be delivered to lower
levels.
This is also known as an allocation or a ration
system.
34
35. DISTRIBUTION SYSTEM …
Conditions favorable to a push system of inventory
management include;
Lower-level staff are not competent in inventory
control.
Demand greatly exceeds supply, making rationing
necessary.
A limited number of products are being handled.
Disaster relief is needed, or the situation calls for
short-term supply through pre-packed kits.
35
36. DISTRIBUTION SYSTEM …
Resupply interval
Once the choice b/n a push or a pull system has
been made, the next step is to select an
appropriate resupply interval .
Determine whether deliveries are made to user
units;
quarterly,
monthly,
weekly or at any other time.
36
37. DISTRIBUTION SYSTEM …
II. Storage
Well-sited stores are vital to the success of
distribution system.
the following points are important to remember
during selection of storage points:
A. Map the demand for drugs
Map the geographical distribution of drug demand,
where are new or expanded health facilities ?
Which ones serve the most people?
37
38. DISTRIBUTION SYSTEM …
B. Locate supply entry points
Airports,
ports,
railway terminals, etc.
C. Select primary storage points
Based on geographic, demographic and
communication factors;
Review the location of the existing primary stores and
consider whether they are well placed for current and
future needs.
D. Plan primary distribution routes & locate
intermediate stores 38
39. DISTRIBUTION SYSTEM …
E. Plan secondary distribution routes
F. Size the stores
The maximum volume of drugs to be held in each
store depends on supply frequency:
programs that receive;
single annual drug deliveries require larger primary
stores
than those supplied more frequently.
39
40. DISTRIBUTION SYSTEM …
Transport
Transport is frequently the least reliable link
in the distribution system & is often a source
of great frustration.
Transport planning requires the selection
of;
appropriate means of transports &
the procurement and maintenance of vehicles
40
41. DISTRIBUTION SYSTEM …
Issues to be considered during
designing Transport system include:
using private–sector alternatives
Planning transport system improvements
Managing vehicle use
Maintaining vehicles
Maintaining drug quality during transport
41
42. DISTRIBUTION SYSTEM …
III. Delivery
Drugs may be;
delivered by warehouses or
collected by health facilities.
Transport may involve;
air,
water,
railway or road vehicles.
Timely delivery of items in health facilities is
very important. 42
43. 5.3. ISSUING PHARMACEUTICALS WITH IN
HEALTH CENTRES AND HOSPITALS
Pharmaceuticals used by a facility should be stored
in the pharmacy storeroom.
When pharmaceuticals are issued from the
storeroom to dispensing unit, the dispensing unit
staff will provide essential logistics data on the
IFRR.
After completing the report section of the form, the
DU staff will take the IFRR to the pharmacy to
obtain the needed pharmaceuticals.
The store manager will use the information in the
report section to determine re-supply quantities and
issue the pharmaceuticals.
43
44. IN HEALTH CENTRES AND HOSPITALS…
When issuing the pharmaceuticals both
the person receiving the pharmaceuticals and
the pharmacy store manager sign the IFRR.
After issuing the pharmaceuticals,
the pharmacy store manager updates the Bin Card,
the pharmacy head updates the Stock Record Card, and
files the IFRR.
44
45. IN HEALTH CENTRES AND HOSPITALS…
Most of the commodities should be stored in the
Health Centre or Hospital pharmacy store.
To maintain the quality of the pharmaceuticals, and
To better management of the pharmaceuticals.
Pharmaceuticals should be issued to the service
providers (nurses, clinicians, out-patient
pharmacies etc.)
In different dispensing units at their work area (in
the ward, in a clinic, in the dispensary) in small
quantities once or more during the month.
45
46. IN HEALTH CENTRES AND HOSPITALS…
completing the IFRR for Issuing Pharmaceuticals within
Health Centers and Hospitals
Task:
Issuing Pharmaceuticals within a health facility
Completed by:
Unit section completed by the person from the DU
reporting/receiving the pharmaceuticals.
Store Section is Completed by the Health Centre or
Hospital pharmacy manager (Pharmacist,
Pharmacy Technician or other)
46
47. IN HEALTH CENTRES AND HOSPITALS…
Purpose:
To report on and issue pharmaceuticals within a
health facility.
When to perform:
According to the schedule established at the
Health Centre/Hospital Pharmacy Store for re-
supply to the dispensing units
During emergency at any time pharmaceuticals are
needed by dispensing units within a health facility.
Materials needed:
IFRR ,
Bin Card(s) for pharmaceuticals being issued,
calculator, and pen
47
48. 5.4. ISSUING PHARMACEUTICALS TO HEALTH
POSTS
At the end of each month, the Health Extension
Worker should bring the HPMRR to the Health
Centre for re-supply.
Using the information contained in the report, and
completed by Health Post, Health Centre staff
determines,
the re-supply quantities and
issue pharmaceuticals to the Health Post staff.
All pharmaceuticals will be re-supplied to the
Maximum Stock Level (2 Months of Stock) each
month.
48
49. HEALTH POSTS…
Completing the Health Centre Section of the HPMRR
when issuing from Health Centre to Health Post)
Task:
Issuing Pharmaceuticals to Health Posts
Completed by:
The Health Centre (Pharmacist, Pharmacy Technician or
others
Purpose:
To re-supply the Health Post with pharmaceuticals up to the
Maximum Stock Level.
49
50. HEALTH POSTS…
When to perform:
At the end of each month when the HEW comes to
the Health Centre for its regular monthly re-supply
When the HEW comes to the Health Centre with an
emergency order
50