1) Populations are aging globally as life expectancies increase, resulting in more people living longer portions of their lives with disability and illness.
2) This aging trends poses massive challenges for public services like healthcare and is straining budgets due to the high costs of caring for older populations.
3) Insurance products that help fund long-term care costs are needed but developing viable products is difficult given the risks involved in insuring an aging population.
With social security not providing as much as hoped and knowing that two-thirds of seniors will become physically, or mentally incapacitated at some point in their lifetime, it’s important to review your Senior Care Options. Nursing Homes are facilities that offer a high degree of medical support and care, and generally serve those seniors who require the most help in performing activities of daily living (ADLs). However, they are also very expensive at nearly $100,000 per year. With Home Care, a family can rely on a home care company to understand the needs of the senior, develop a plan of care, and pro-actively monitor their health and day-to-day needs.
With social security not providing as much as hoped and knowing that two-thirds of seniors will become physically, or mentally incapacitated at some point in their lifetime, it’s important to review your Senior Care Options. Nursing Homes are facilities that offer a high degree of medical support and care, and generally serve those seniors who require the most help in performing activities of daily living (ADLs). However, they are also very expensive at nearly $100,000 per year. With Home Care, a family can rely on a home care company to understand the needs of the senior, develop a plan of care, and pro-actively monitor their health and day-to-day needs.
DO HOUSEHOLDS HAVE A GOOD SENSE OF THEIR RETIREMENT PREPAREDNESS?Chad Azara, AIF, MBA
The National Retirement Risk Index (NRRI) measures
the percentage of working-age households who
are at risk of being financially unprepared for retirement.
White Paper from the Center for Retirement Research written by Alicia H. Munnell, Wenliang Hou, and Geoffrey T. Sanzenbacher*
Demographic science aids in understanding the spread and fatality rates of CO...Wouter de Heij
See also:
https://osf.io/fd4rh/?view_only=c2f00dfe3677493faa421fc2ea38e295
and live-blog:
https://food4innovations.blog/2020/03/16/live-blog-over-de-corona-crisis-covid-19-dagelijkse-beschouwingen-van-wouter-de-heij-food4innovations/
Reconstructing the social determinants of healthCitizen Network
Dr Simon Duffy of the Centre for Welfare Reform explores how we can reconstruct the social determinants of health and begin to address the real drivers of inequality and poor health. This talk was given to leaders of public health in Yorkshire.
David Buck’s slidepack sets out some basic statistics on the state of the English population’s health, including life expectancy, health inequalities and tobacco and alcohol use.
2013.04.17 The usefulness of a national wellbeing index for Public PolicyNUI Galway
Professor Liam Delaney, University of Stirling, UK presented this seminar "The usefulness of a national wellbeing index for Public Policy" as part of the Visiting Fellows Seminar Series at the Whitaker Institute on 17th April 2013.
National Institute on AgingNational Institutes of HealthU..docxvannagoforth
National Institute on Aging
National Institutes of Health
U.S. Department of Health and Human Services
Global Health and Aging
2 Global Health and AgingPhoto credits front cover, left to right (Dreamstime.com): Djembe; Sergey Galushko; Laurin Rinder; Indianeye;
Magomed Magomedagaev; and Antonella865.
3
Preface
Overview
Humanity’s Aging
Living Longer
New Disease Patterns
Longer Lives and Disability
New Data on Aging and Health
Assessing the Cost of Aging and Health Care
Health and Work
Changing Role of the Family
Suggested Resources
Contents
Rose Maria Li
1
2
4
6
9
12
16
18
20
22
25
4 Global Health and Aging
5
Preface
The world is facing a situation without precedent: We soon will have more older people than
children and more people at extreme old age than ever before. As both the proportion of older
people and the length of life increase throughout the world, key questions arise. Will population
aging be accompanied by a longer period of good health, a sustained sense of well-being, and
extended periods of social engagement and productivity, or will it be associated with more illness,
disability, and dependency? How will aging affect health care and social costs? Are these futures
inevitable, or can we act to establish a physical and social infrastructure that might foster better
health and wellbeing in older age? How will population aging play out differently for low-income
countries that will age faster than their counterparts have, but before they become industrialized
and wealthy?
This brief report attempts to address some of these questions. Above all, it emphasizes the central
role that health will play moving forward. A better understanding of the changing relationship
between health with age is crucial if we are to create a future that takes full advantage of the
powerful resource inherent in older populations. To do so, nations must develop appropriate
data systems and research capacity to monitor and understand these patterns and relationships,
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well-being. And research needs to be better coordinated if we are to discover the most cost-effective
ways to maintain healthful life styles and everyday functioning in countries at different stages of
economic development and with varying resources. Global efforts are required to understand and
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existing knowledge about the prevention and treatment of heart disease, stroke, diabetes, and
cancer.
Managing population aging also requires building needed infrastructure and institutions as soon as
possible. The longer we delay, the more costly and less effective the solutions are likely to be.
Population aging is a powerful and transforming demographic force. We are only just beginning
to comprehend its impact ...
Increased Risk of Falls Everyone strives to feel safe aLizbethQuinonez813
Increased Risk of Falls
Everyone strives to feel safe and comfortable in their living surroundings. With age comes the necessity to keep one's mind at ease while going about one's everyday tasks. In older individuals, falls are the primary cause of fatal and nonfatal injuries. Because of the increasing incidence of frailty and a limited physiologic reserve among the aging population, fatal falls occur in persons of all ages, but those over 75 experience higher rates of morbidity and mortality. Falls are the primary cause of injury-related emergency room visits, especially among the elderly. Falls can cause injuries such as hip fractures, brain injuries, and rib fractures. Depression, social isolation, and limitations in their other activities are some of the additional drawbacks. Falls, whether they cause harm, have a significant influence on one's quality of life, especially for the elderly. As a result of their fear of falling, an increasing number of older adults are limiting their activities and social engagements. Therefore, as nurses, ensure assess fall risks and prevent falls in older adults.
I. Falls are a frequent clinical condition that affects approximately half of all Americans over the age of 65.
A. An older adult is treated in the emergency room after a fall every 11 seconds.
1. Because of the higher incidence of frailty and a limited physiologic reserve among the elderly, falling causes higher rates of morbidity and mortality among individuals over 75.
a. It is typical for elderly adults to have multiple chronic health conditions, as well as a loss of physical strength and bone density. Those are the ones who induce them to fall and easily fracture their bones.
b. Muscle strength, balance, and reaction time all decline as we age which put older adults at a significant risk of falling.
II. There are many risk factors of fall in elderly.
A. Polypharmacy, antipsychotic drugs, visual deficit, and cognitive impairment can cause falls in older adults.
1. Many older adults take multiple drugs daily and receive treatment from different physicians. As well as they tend to take antipsychotic drugs for depression or other mental illnesses.
a. For instance, many elderlies have hypertension, and sometimes they take both diuretics and antihypertensive medication for it. These combined medications may cause severe hypotension and risk for falls.
b. Many older adults must depend on other people with ADLs, lost their loved ones, lonely, and depressed, so they take antipsychotic drugs to minimize these conditions. Antipsychotic medications might cause drowsiness and risk for falls.
III. Nursing management of falls
A. Management of fall is challenge for nurses, but there are several ways to reduce falls.
1. Encourage fall risk clients to wear slip resistant socks or shoes, reinforce to use call light before getting up, rise and reposition slowly, use walker, stay within arm’s reach, use bed alarm or chair alarm, and answer call lig ...
Chapter Five Older People and Long-Term Care Issues of Access.docxmccormicknadine86
Chapter Five
Older People and Long-Term Care: Issues of Access
1
2
Why the new interest in long-term care?
The Baby Boomers are adding to the growth in the population over 65.
There is increasing fear of dependency on long-term care.
Adult children of the elderly having to find care for their parents.
Healthcare reform promises great changes that are not well understood.
3
3
The Growing Population Needing Care
The need for ADL and IADL assistance continues to grow.
Table 8-1 presents the broad range of services needed by the disabled.
Most of the population needing long-term care do not live in nursing homes.
Many factors contribute to the inability to predict the exact number needing services in the future.
4
4
The Growing Population Needing Care
Future populations may be better educated which is associated with lower levels of disability.
Ethnic composition suggests a greater need for care and government support.
Boomers will bring greater numbers of people needing services.
The number of those over 75 will greatly increase.
5
5
The Growing Population Needing Care
Disability rates will increase among those who are not in nursing homes.
The most common disability is physical.
In addition, the nursing home population is expected to have profound increases until it triples by 2030.
The number of younger persons with disability has also increased.
6
6
Issues of Access
The current system is far from ideal.
There is not an adequate supply particularly for the poor.
The system itself continues to be so fragmented that many are not aware of what is offered.
Financing is an underlying problem.
7
7
The Costs of Care
Expenses for this care are sizable and will increase in the future.
Private insurance only pays for a small percentage of the care.
Medicaid pays for over 85% of nursing home care.
8
8
The Costs of Care
Annual costs of nursing home care can average $58,000 per year and may exceed $100,000. For many, the costs of this care is just not affordable.
With the addition of the Baby Boomers, costs will most certainly increase in the future.
The effects of reform are not currently known.
9
9
The Care-giving Role of Families
About 74% of dependent community-based elders receive care from family members.
The majority of caregivers are women.
The number and willingness of family caregivers may decline as the Boomers become in need for assistance.
10
10
The Role of Private Insurance
Private insurance for long-term care is a relatively new product.
Improvements in coverage are being made, but only an estimated 20% of the population will use it.
CCRCs and LCAHs hold promise for the future.
11
11
The Role of Medicaid
Medicaid is changing under PPACA to include more eligible adults who will receive benchmark coverage.
Medicaid is used for those elders who meet certain criteria.
Medicaid does not pay for the full range of services including home-based care.
Some states are using a waiver to offe ...
Chapter Five Older People and Long-Term Care Issues of Access.docxtiffanyd4
Chapter Five
Older People and Long-Term Care: Issues of Access
1
2
Why the new interest in long-term care?
The Baby Boomers are adding to the growth in the population over 65.
There is increasing fear of dependency on long-term care.
Adult children of the elderly having to find care for their parents.
Healthcare reform promises great changes that are not well understood.
3
3
The Growing Population Needing Care
The need for ADL and IADL assistance continues to grow.
Table 8-1 presents the broad range of services needed by the disabled.
Most of the population needing long-term care do not live in nursing homes.
Many factors contribute to the inability to predict the exact number needing services in the future.
4
4
The Growing Population Needing Care
Future populations may be better educated which is associated with lower levels of disability.
Ethnic composition suggests a greater need for care and government support.
Boomers will bring greater numbers of people needing services.
The number of those over 75 will greatly increase.
5
5
The Growing Population Needing Care
Disability rates will increase among those who are not in nursing homes.
The most common disability is physical.
In addition, the nursing home population is expected to have profound increases until it triples by 2030.
The number of younger persons with disability has also increased.
6
6
Issues of Access
The current system is far from ideal.
There is not an adequate supply particularly for the poor.
The system itself continues to be so fragmented that many are not aware of what is offered.
Financing is an underlying problem.
7
7
The Costs of Care
Expenses for this care are sizable and will increase in the future.
Private insurance only pays for a small percentage of the care.
Medicaid pays for over 85% of nursing home care.
8
8
The Costs of Care
Annual costs of nursing home care can average $58,000 per year and may exceed $100,000. For many, the costs of this care is just not affordable.
With the addition of the Baby Boomers, costs will most certainly increase in the future.
The effects of reform are not currently known.
9
9
The Care-giving Role of Families
About 74% of dependent community-based elders receive care from family members.
The majority of caregivers are women.
The number and willingness of family caregivers may decline as the Boomers become in need for assistance.
10
10
The Role of Private Insurance
Private insurance for long-term care is a relatively new product.
Improvements in coverage are being made, but only an estimated 20% of the population will use it.
CCRCs and LCAHs hold promise for the future.
11
11
The Role of Medicaid
Medicaid is changing under PPACA to include more eligible adults who will receive benchmark coverage.
Medicaid is used for those elders who meet certain criteria.
Medicaid does not pay for the full range of services including home-based care.
Some states are using a waiver to offe.
Making your money last in retirement - Aviva's longevity reportAviva plc
In our making your money last in retirement special report we compare and consider consumer attitudes to the facts about longevity, and make some clear recommendations about how the government and the industry must respond.
Making your money last in retirement - Aviva's longevity reportAviva plc
In our making your money last in retirement special report we compare and consider consumer attitudes to the facts about longevity, and make some clear recommendations about how the government and the industry must respond.
In the course of the last several years, millennials have shown that they are very different from previous generations in a number of ways. Defined as the generation born from 1981 to 1996, they are the largest, most educated, and most connected generation the world has ever seen1. However, recent data also show the beginnings of troubling generational health patterns that could hamper the future prosperity of millennials, and in turn the prosperity of the U.S. If the current pace of decline in millennial health continues unabated, the long-term consequences to the U.S. economy could be severe.
DO HOUSEHOLDS HAVE A GOOD SENSE OF THEIR RETIREMENT PREPAREDNESS?Chad Azara, AIF, MBA
The National Retirement Risk Index (NRRI) measures
the percentage of working-age households who
are at risk of being financially unprepared for retirement.
White Paper from the Center for Retirement Research written by Alicia H. Munnell, Wenliang Hou, and Geoffrey T. Sanzenbacher*
Demographic science aids in understanding the spread and fatality rates of CO...Wouter de Heij
See also:
https://osf.io/fd4rh/?view_only=c2f00dfe3677493faa421fc2ea38e295
and live-blog:
https://food4innovations.blog/2020/03/16/live-blog-over-de-corona-crisis-covid-19-dagelijkse-beschouwingen-van-wouter-de-heij-food4innovations/
Reconstructing the social determinants of healthCitizen Network
Dr Simon Duffy of the Centre for Welfare Reform explores how we can reconstruct the social determinants of health and begin to address the real drivers of inequality and poor health. This talk was given to leaders of public health in Yorkshire.
David Buck’s slidepack sets out some basic statistics on the state of the English population’s health, including life expectancy, health inequalities and tobacco and alcohol use.
2013.04.17 The usefulness of a national wellbeing index for Public PolicyNUI Galway
Professor Liam Delaney, University of Stirling, UK presented this seminar "The usefulness of a national wellbeing index for Public Policy" as part of the Visiting Fellows Seminar Series at the Whitaker Institute on 17th April 2013.
National Institute on AgingNational Institutes of HealthU..docxvannagoforth
National Institute on Aging
National Institutes of Health
U.S. Department of Health and Human Services
Global Health and Aging
2 Global Health and AgingPhoto credits front cover, left to right (Dreamstime.com): Djembe; Sergey Galushko; Laurin Rinder; Indianeye;
Magomed Magomedagaev; and Antonella865.
3
Preface
Overview
Humanity’s Aging
Living Longer
New Disease Patterns
Longer Lives and Disability
New Data on Aging and Health
Assessing the Cost of Aging and Health Care
Health and Work
Changing Role of the Family
Suggested Resources
Contents
Rose Maria Li
1
2
4
6
9
12
16
18
20
22
25
4 Global Health and Aging
5
Preface
The world is facing a situation without precedent: We soon will have more older people than
children and more people at extreme old age than ever before. As both the proportion of older
people and the length of life increase throughout the world, key questions arise. Will population
aging be accompanied by a longer period of good health, a sustained sense of well-being, and
extended periods of social engagement and productivity, or will it be associated with more illness,
disability, and dependency? How will aging affect health care and social costs? Are these futures
inevitable, or can we act to establish a physical and social infrastructure that might foster better
health and wellbeing in older age? How will population aging play out differently for low-income
countries that will age faster than their counterparts have, but before they become industrialized
and wealthy?
This brief report attempts to address some of these questions. Above all, it emphasizes the central
role that health will play moving forward. A better understanding of the changing relationship
between health with age is crucial if we are to create a future that takes full advantage of the
powerful resource inherent in older populations. To do so, nations must develop appropriate
data systems and research capacity to monitor and understand these patterns and relationships,
��������
� �
������
� ���������������
��������������������� ���� �������
�����������������
���
��
well-being. And research needs to be better coordinated if we are to discover the most cost-effective
ways to maintain healthful life styles and everyday functioning in countries at different stages of
economic development and with varying resources. Global efforts are required to understand and
�
�������������
����������
������������� ������������������ �����������
������ �
��
�������� ���
��
existing knowledge about the prevention and treatment of heart disease, stroke, diabetes, and
cancer.
Managing population aging also requires building needed infrastructure and institutions as soon as
possible. The longer we delay, the more costly and less effective the solutions are likely to be.
Population aging is a powerful and transforming demographic force. We are only just beginning
to comprehend its impact ...
Increased Risk of Falls Everyone strives to feel safe aLizbethQuinonez813
Increased Risk of Falls
Everyone strives to feel safe and comfortable in their living surroundings. With age comes the necessity to keep one's mind at ease while going about one's everyday tasks. In older individuals, falls are the primary cause of fatal and nonfatal injuries. Because of the increasing incidence of frailty and a limited physiologic reserve among the aging population, fatal falls occur in persons of all ages, but those over 75 experience higher rates of morbidity and mortality. Falls are the primary cause of injury-related emergency room visits, especially among the elderly. Falls can cause injuries such as hip fractures, brain injuries, and rib fractures. Depression, social isolation, and limitations in their other activities are some of the additional drawbacks. Falls, whether they cause harm, have a significant influence on one's quality of life, especially for the elderly. As a result of their fear of falling, an increasing number of older adults are limiting their activities and social engagements. Therefore, as nurses, ensure assess fall risks and prevent falls in older adults.
I. Falls are a frequent clinical condition that affects approximately half of all Americans over the age of 65.
A. An older adult is treated in the emergency room after a fall every 11 seconds.
1. Because of the higher incidence of frailty and a limited physiologic reserve among the elderly, falling causes higher rates of morbidity and mortality among individuals over 75.
a. It is typical for elderly adults to have multiple chronic health conditions, as well as a loss of physical strength and bone density. Those are the ones who induce them to fall and easily fracture their bones.
b. Muscle strength, balance, and reaction time all decline as we age which put older adults at a significant risk of falling.
II. There are many risk factors of fall in elderly.
A. Polypharmacy, antipsychotic drugs, visual deficit, and cognitive impairment can cause falls in older adults.
1. Many older adults take multiple drugs daily and receive treatment from different physicians. As well as they tend to take antipsychotic drugs for depression or other mental illnesses.
a. For instance, many elderlies have hypertension, and sometimes they take both diuretics and antihypertensive medication for it. These combined medications may cause severe hypotension and risk for falls.
b. Many older adults must depend on other people with ADLs, lost their loved ones, lonely, and depressed, so they take antipsychotic drugs to minimize these conditions. Antipsychotic medications might cause drowsiness and risk for falls.
III. Nursing management of falls
A. Management of fall is challenge for nurses, but there are several ways to reduce falls.
1. Encourage fall risk clients to wear slip resistant socks or shoes, reinforce to use call light before getting up, rise and reposition slowly, use walker, stay within arm’s reach, use bed alarm or chair alarm, and answer call lig ...
Chapter Five Older People and Long-Term Care Issues of Access.docxmccormicknadine86
Chapter Five
Older People and Long-Term Care: Issues of Access
1
2
Why the new interest in long-term care?
The Baby Boomers are adding to the growth in the population over 65.
There is increasing fear of dependency on long-term care.
Adult children of the elderly having to find care for their parents.
Healthcare reform promises great changes that are not well understood.
3
3
The Growing Population Needing Care
The need for ADL and IADL assistance continues to grow.
Table 8-1 presents the broad range of services needed by the disabled.
Most of the population needing long-term care do not live in nursing homes.
Many factors contribute to the inability to predict the exact number needing services in the future.
4
4
The Growing Population Needing Care
Future populations may be better educated which is associated with lower levels of disability.
Ethnic composition suggests a greater need for care and government support.
Boomers will bring greater numbers of people needing services.
The number of those over 75 will greatly increase.
5
5
The Growing Population Needing Care
Disability rates will increase among those who are not in nursing homes.
The most common disability is physical.
In addition, the nursing home population is expected to have profound increases until it triples by 2030.
The number of younger persons with disability has also increased.
6
6
Issues of Access
The current system is far from ideal.
There is not an adequate supply particularly for the poor.
The system itself continues to be so fragmented that many are not aware of what is offered.
Financing is an underlying problem.
7
7
The Costs of Care
Expenses for this care are sizable and will increase in the future.
Private insurance only pays for a small percentage of the care.
Medicaid pays for over 85% of nursing home care.
8
8
The Costs of Care
Annual costs of nursing home care can average $58,000 per year and may exceed $100,000. For many, the costs of this care is just not affordable.
With the addition of the Baby Boomers, costs will most certainly increase in the future.
The effects of reform are not currently known.
9
9
The Care-giving Role of Families
About 74% of dependent community-based elders receive care from family members.
The majority of caregivers are women.
The number and willingness of family caregivers may decline as the Boomers become in need for assistance.
10
10
The Role of Private Insurance
Private insurance for long-term care is a relatively new product.
Improvements in coverage are being made, but only an estimated 20% of the population will use it.
CCRCs and LCAHs hold promise for the future.
11
11
The Role of Medicaid
Medicaid is changing under PPACA to include more eligible adults who will receive benchmark coverage.
Medicaid is used for those elders who meet certain criteria.
Medicaid does not pay for the full range of services including home-based care.
Some states are using a waiver to offe ...
Chapter Five Older People and Long-Term Care Issues of Access.docxtiffanyd4
Chapter Five
Older People and Long-Term Care: Issues of Access
1
2
Why the new interest in long-term care?
The Baby Boomers are adding to the growth in the population over 65.
There is increasing fear of dependency on long-term care.
Adult children of the elderly having to find care for their parents.
Healthcare reform promises great changes that are not well understood.
3
3
The Growing Population Needing Care
The need for ADL and IADL assistance continues to grow.
Table 8-1 presents the broad range of services needed by the disabled.
Most of the population needing long-term care do not live in nursing homes.
Many factors contribute to the inability to predict the exact number needing services in the future.
4
4
The Growing Population Needing Care
Future populations may be better educated which is associated with lower levels of disability.
Ethnic composition suggests a greater need for care and government support.
Boomers will bring greater numbers of people needing services.
The number of those over 75 will greatly increase.
5
5
The Growing Population Needing Care
Disability rates will increase among those who are not in nursing homes.
The most common disability is physical.
In addition, the nursing home population is expected to have profound increases until it triples by 2030.
The number of younger persons with disability has also increased.
6
6
Issues of Access
The current system is far from ideal.
There is not an adequate supply particularly for the poor.
The system itself continues to be so fragmented that many are not aware of what is offered.
Financing is an underlying problem.
7
7
The Costs of Care
Expenses for this care are sizable and will increase in the future.
Private insurance only pays for a small percentage of the care.
Medicaid pays for over 85% of nursing home care.
8
8
The Costs of Care
Annual costs of nursing home care can average $58,000 per year and may exceed $100,000. For many, the costs of this care is just not affordable.
With the addition of the Baby Boomers, costs will most certainly increase in the future.
The effects of reform are not currently known.
9
9
The Care-giving Role of Families
About 74% of dependent community-based elders receive care from family members.
The majority of caregivers are women.
The number and willingness of family caregivers may decline as the Boomers become in need for assistance.
10
10
The Role of Private Insurance
Private insurance for long-term care is a relatively new product.
Improvements in coverage are being made, but only an estimated 20% of the population will use it.
CCRCs and LCAHs hold promise for the future.
11
11
The Role of Medicaid
Medicaid is changing under PPACA to include more eligible adults who will receive benchmark coverage.
Medicaid is used for those elders who meet certain criteria.
Medicaid does not pay for the full range of services including home-based care.
Some states are using a waiver to offe.
Making your money last in retirement - Aviva's longevity reportAviva plc
In our making your money last in retirement special report we compare and consider consumer attitudes to the facts about longevity, and make some clear recommendations about how the government and the industry must respond.
Making your money last in retirement - Aviva's longevity reportAviva plc
In our making your money last in retirement special report we compare and consider consumer attitudes to the facts about longevity, and make some clear recommendations about how the government and the industry must respond.
In the course of the last several years, millennials have shown that they are very different from previous generations in a number of ways. Defined as the generation born from 1981 to 1996, they are the largest, most educated, and most connected generation the world has ever seen1. However, recent data also show the beginnings of troubling generational health patterns that could hamper the future prosperity of millennials, and in turn the prosperity of the U.S. If the current pace of decline in millennial health continues unabated, the long-term consequences to the U.S. economy could be severe.
Reactive Vs. Preventative Healthcare for Seniorsrachelgmoore
Exorbitant costs are breaking the back of the nation's healthcare system, and seniors are shouldering significantly more than their fair share of the burden. A large portion of these costs are due to a reactive healthcare model - one that only addresses problems after they arise.
In this infographic, learn about how a shift towards a preventative care model for seniors can decrease healthcare costs, improve quality of care, and quality of life, as well as some of the technologies senior living and care providers can use to promote preventative care and their organizations.
Get the high resolution version here: http://hubs.ly/y0Yj4b0
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
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1. Living longer. Living poorer.
The challenge of caring
for a greying population
infocus
Issue No. 67, April 2015
2. Here’s the good news: we are all living longer, not just from
birth but our life expectancy at retirement has increased. By
2062 females are projected to be living 60% longer than in
1982 and male life expectancy at 65 will have almost doubledi.
A lot of this is owed to increased survival from circulatory
disease (and heart attacks in particular) and a related decrease
in smoking prevalence. Coupled with generally falling or flat
birth rates, in the West at least, as a result we are witnessing
a profound demographic shift as the number of over 60s will
double in the first half of the 21st century and the number of
the oldest old (>85) will treble.
And here’s the bad news, while we are living longer, a third of
our older age is spent dealing with profound ill-health. So for
example, while the average 65 year old in 2010 could expect
to live until their mid-80s, their last twelve years would be
spent with disabilityii.
These changes have massive implications in almost all areas
of public planning, from health and social care provision to
volume of tax receipts as people exit the workplace. A glance
of the newspaper headlines show that these are fast becoming
urgent political problems being wrestled with across the globe,
Graph 1: Growth in over 60s and Alzheimer disease: UK
Proportion of over 60s with Alzheimer’s
from issues to funding the NHS in the UK, to the success of
Obamacare in the USA and Abenomics in Japaniii.
As mentioned above, medical science’s success in tackling the
mortality associated with the triple scourge of ischaemic heart
2 | Hannover Re UK Life Branch
2005
0m
5m
10m
15m
20m
25m 10%
8%
6%
4%
2%
0%
2013 2015 2020 2025 2051
3. Parkinsonian diseases. As graph 1 and 2 demonstrate, the
number of over 65’s is directly correlated with a surge in
these diseases. However, increases in single diseases is not
the whole problem as one of the features of ageing is that
ill-health and disability is seldom caused by one or even two
chronic illnesses but a constellation of co-morbidity. Care costs
for the elderly, whether funded by the state or individually, will
consequently and exponentially increase as we live longer but in
poorer health.
Should we be worried?
Given the elderly already consume three times more acute care
services and ten time more long-term care than the non-elderly
per capita, it is a simple fact of economics that governments
cannot afford to fund the spiralling costs associated with this
demographic change and the resulting need for elderly careiv.
In the US for example, Medicare is predicted to run out by
2030v, and in the UK, while the Government has allocated the
seemingly huge figure of £3.8bn for the ‘Better Care Fund’,
and 57% of local government spending is on social care for the
elderly, it’s clear such continued expenditure is unsustainablevi.
Amongst the public, the idea that we must make our own
Graph 2: Global projected number of people over 50
with Parkinson’s Disease 2005-2030
China W. Europe USA India
Russia Brazil Japan
disease, cancer and tobacco addiction has meant a rise in the
prevalence of more insidious ill-health issues, particularly
those associated with neuro-degeneration; dementias and
Hannover Re UK Life Branch | 3
2005
0m
1m
2m
3m
4m
5m
2010 2015 2020 2025 2030
4. Graph 3: Would consumers buy an insurance product that provided
funds for care in old age (their own care or that of a relative)?
Yes No Not sure
It is essential therefore, that the Life and Health Insurance
industry provides affordable and accessible products to
meet this increasing requirement for both disability and care
provision in the over 60s. And we must go further than that,
convincing the public that these products are not only available,
but are an absolute need. Of course designing and pricing these
products is tricky given the burden of risks involved.
provision for care needs is beginning to take root, with worries
about old age care costs topping a list of financial worries for
45-65 year olds in a recent surveyvii. However, society appears
to be lethargic about actually doing something about these fears
as 90% of over 65 year olds have no long term care provisionviii.
However there are signs this may be changing. Research from
The Syndicate 2015 shows there is a growing propensity,
especially in the younger generations, to consider purchasing
an insurance product to help fund care in old age. Nearly one
quarter of the survey respondents claimed they would consider
purchasing an insurance product to fund their care in old age,
mainly ‘not to be a burden’ on others and society. These findings
were particularly interesting when compared to the percentage
that instead showed interest in purchasing an insurance product
to fund relatives’ care, which was just 12% (see graph 3).
Clearly there is a growing perception amongst consumers that
funding care in old age should be an individual responsibilityix.
Lack of finance and poor financial planning leads ultimately to
lack of choice, and choice is clearly important for end of life care
as only around 3% would like to be cared for in a residential
care home; the majority would prefer to be at homex.
4 | Hannover Re UK Life Branch
Caring for
relatives
Their care
in old age
23% 35% 42%
12% 49% 40%
5. Frailty
One way to measure this burden is to assess the prevalence
of frailty. There is no precise universally accepted definition
of frailty, but it is generally seen as an increased risk of poor
health because of progressive decline in the function and
capacity of multiple body systems. More simply it is a failure
to ‘bounce back’ and be resilient to life events. As we age,
we become more likely to die or be permanently ill. Frailty
therefore is strongly correlated with age (see table 1).
Table 1: Presence of Frailty in Canada. Rookwood 2011xi
Age 15-39 40-69 >70
Relatively fit 61.5% 47.5% 22.6%
Less fit 25.9% 28.5% 30.2%
Least fit 10.2% 16.0% 25.0%
Frail 2.4% 8.0% 22.2%
There have been a number of attempts to classify what frailty
precisely means; Fried and colleagues for example see it as a
specific syndrome or phenotype, characterised by the presence
of three of the following highly specific attributes; weight loss,
exhaustion, weakness (usually measured as grip strength),
slowness and low activity measuresxii. Alternatively Rookwood
and colleagues in Canada see frailty as a state that presents
itself because of the accumulation of a set of deficits in a frailty
index (FI); those with few deficits are ‘fit’ whilst those with
many are ‘frail’. Typically a FI consists of around 30-70 deficits
(see Appendix 1 for an example) ranging from the presence
of certain diseases (Alzheimer’s, Parkinson’s, Diabetes etc.),
disabilities (sight, hearing loss etc.) and functional abilities
(dressing, washing, shopping etc.)xiii Numerous studies ranging
from China, the USA, Canada and Europe have shown that a
FI score of >0.15 (6 out of 40 deficits present for example) is
a better predictor of death than chronological agexiv. Use of a
frailty index could be an excellent method of differentiating
between individual risks in the older population.
However, one of the flaws with a fully-fledged FI model is the
complexity and number of variables involved in terms of assessing
whether an individual is frail or not. Instead a modified, simpler
and more understandable method would be to use assessments
of Activities of Daily Living (ADL); this has a further advantage
in that these are widely understood by the life insurance industry
and are adequately adaptable in any disability product design.
Hannover Re UK Life Branch | 5
6. any top-up care provision over and above that deemed essential.
Table 2: ADLs v IADLs
Activities of Daily Living (ADL)
Instrumental Activities
of Daily Living (IADLS)
Essential activities that are a
requirement of life, these include:
• Bathing
• Dressing
• Communication
• Feeding
• Toileting
• Movement between rooms
and/or in and out of bed
Devised by Lawton in 1969, these
are actions or tasks that measure
ability to perform in the general
community setting, these include:
• Housework
• Taking medications
as prescribed
• Managing money
• Shopping for groceries
or clothing
• Use of telephone or other form
of communication
• Using technology (as applicable)
• Transportation within
the community
There is therefore clearly a need for the provision of financial
products to enable people to pay for the care they need and expect
without exhausting their lifetime savings or selling their homes.
At Hannover Re UK Life Branch we have successfully worked with
a number of clients on devising and creating products to meet
For example, having ADL disability adds roughly 10 years to
age or halves life expectancy in older lives. In underwriting
terms having at least 1 ADL disability is equivalent to 50-100%
extra mortalityxv, xvi. There are several different scales of ADL
(see table 2), but the two most common are basic ADL (widely
used in Critical Illness insurance) and instrumental type (IADL).
One way to differentiate between them is to think that they
measure different stages of care need, IADLs assess whether
a person requires assistance, whereas ADLs assess whether
a person needs constant care. Both of these measures could
be used as different triggers for different payment events.
Of course ADL/IADL are very physical measures, they don’t
capture any cognitive impairment (as in Dementia) until fairly
advanced. A product aimed at long-term care should therefore
also include provision for claim pay out for cognitive decline.
With the UK Care Act (May 2014) recently gaining royal assent,
some of the issues around the sustainability of funding care
and its impact on both public and individual finance are being
addressed. However some fundamental problems remain; while
this legislation safeguards that an individual should in their
lifetime pay no more than a specific cap (currently £72,000), it
excludes accommodation costs (the ‘bed and board’ fees) and
6 | Hannover Re UK Life Branch
7. Hannover Re UK Life Branch | 7
Appendix 1
Variables in a typical Frailty Index.
FRAILTY
Physical
Cardiovascular/
Pulmonary
Neuro-degenerative Sensory Psychological Other Morbidity
• Falls
• Activity level
• Walking ability
• Dressing
• Bathing
• Going out
• Low/High BMI
• Arthritis
• MI/Angina
• Stroke
• Hypertension
• Tachycardia
• Chronic Obstructive
Airways Disease
• Bronchitis
• Shortness of breath
• Asthma
• Alzheimer’s
• Dementia
• Parkinson’s
• Other cognitive
decline
• Hearing difficulty
• Deafness
• Eyesight problems
• Cataracts
• Glaucoma
• Depression
• Low mood
• Social isolation
• Cancer
• Diabetes
• Thyroid disease
• Ulcers
these needs. This work has been derived from our experience in
the health, life and longevity sectors. We would be delighted to
discuss this or any other product innovation with you.
Paul Edwards
Manager Medical Risk
Sources:
i ONS http://www.ons.gov.uk/ons/dcp171778_345078.pdf
ii Later Life in the UK, October 2014, Age UK
iii The Economist, ’Age Invaders’ 24 April 2014
iv Jackson, R., Howe, N., and Peter, T., ‘The Global Aging Preparedness
Index’ 2nd Ed 2013. Centre for Strategic & International Studies
v Reuters, July 28 2014, http://www.reuters.com/article/2014/07/28/
usa-fiscal-health-idUSL2N0Q310320140728
vi Age UK, Care in Crisis 2014, http://www.ageuk.org.uk/
Documents/EN-GB/Campaigns/CIC/Care_in_Crisis_report_2014.
pdf?epslanguage=en-GB?dtrk%3dtrue
Continued overleaf