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The Caring Does Matter (CDM) Initiative:
To Improve Cardiovascular Medication
Adherence in Pacific People


Jim Warren, Yulong Gu (Helen), John Kennelly




                             The National Institute
                             for Health Innovation
Why the interest?

 • Burning platform
   –   Increased rates of chronic illness
   –   Ageing population
   –   Cost / workforce / delivery meltdown!
   –   Even if we were satisfied with current quality
       of health delivery, it’s not sustainable
 • Long-term conditions as the target
 • Lots of data
   – Computerisation naturally lays down data, which
     can be used to improve patient management
Chronic conditions, esp. anything
‘vascular’
• Amenable (and interesting) for analysis of
  long sequences in transactional electronic
  health records (EHRs)
• E.g. blood pressure (BP) is a huge risk factor
  – CVD risk doubles for every 20/10 mm Hg
      • Also implicated in kidney failure
  – Very controllable with medication
  – Several classes of medication with different side-
    effects and benefits/indications (makes it
    interesting!)
• Statins/cholesterol and blood sugar control
  also very relevant
CDM Initiative

• A feasibility study
   – Structured care, based on West Fono program
• To identify and intervene on suboptimal
  management of CVR
   – Medication adherence gaps - MPR
How to identify intervention targets?

• Demographics
• CVR scores
• Prescriptions
Pacific adults (20+) grouped into 4:

 having high CVR risk (>=10%) and low
  MPR (<80%)
 having no CVR screening recorded in
  the last five years and aged 35 or over
 having high CVR risk (>=10%) but
  MPR OK (>=80%)
 having low CVR risk (<10%) or having
  no CVR screening recorded in the last
  five years but being younger than 35
Group 1 Patient List example
Pt Age Gen-     Eth-        Anti-                   Oral     Last CVR
ID      der    nicity   hypertensives Cholesterol Diabetes   screening CVR
                                                 medications    date
1   64   M    Tongan    None         <80%        None       30-Sep-11   99

2   60   F    Samoan OK              OK          <80%       13-Mar-12   99

3   51   M    Samoan None            <80%        None       6-Sep-11    99
              Other
4   81   M              OK           None        <80%       11-Nov-11   30
              Pacific
5   63   M    Samoan <80%            Recent start None      19-Oct-11   22

6   62   M    Samoan <80%            None        None       14-Apr-12   22

7   65   M    Samoan <80%            <80%        <80%       10-Jan-12   21

8   63   M    Samoan <80%            <80%        <80%       17-Jul-11   18

9   58   F    Samoan <80%            None        None       16-May-12   16

10 63    M    Fijian    None         None        None       22-Jul-09   15
…
9,128 Pacific adults in 10 clinics
Clinics     Practice        Pacific patient       Pacific patient Pacific patient
  ID        patient    population # (% in total    population      population
          population #   practice population)         20+ #           35+ #
  A            6884          5144    (75%)               3060            2001

  B           12984          1872    (14%)               1038             627

  C            5696          1634    (29%)                934             600

  D           11939          1481    (12%)                764             470

  E            4794          1355    (28%)                726             471

  F            5863          1316    (22%)                702             438

  G           13112          1114     (8%)                610             384

  H            1564          1103    (71%)                669             429

   I           4875           583    (12%)                331             194

   J           9633           534    (16%)                294             171

Total:       77344         16136    (21%)               9128            5785
1,021 with high CVR & low MPR
Practice High CVR & low MPR # (%          No CVR & 35+ # (% in
   ID    in Pacific 20+ at the clinics)       Pacific 35+)
   A               522 (17%)                   855 (43%)
   B                67 (6%)                    370 (59%)
   C                91 (10%)                   297 (50%)
   D                58 (8%)                    293 (62%)
   E                61 (8%)                    207 (44%)
   F                50 (7%)                    272 (62%)
   G                55 (9%)                    195 (51%)
   H                71 (11%)                   157 (37%)
   I                29 (9%)                     51 (26%)
   J                17 (6%)                    115 (67%)
 Total:          1021 (11%)                   2812 (49%)
CVR profile of Group 1

                          99
                 45-49   14%
            40-44 0%
    35-39    0%
     3%
        30-34
         1%
      25-29                    10-14
       4%                       43%
                20-24
                 10%




            15-19
             25%
Physiological profile of Group 1
           Measurements                   Mean Standard       Pt # (%)
                                               deviation    measured in
                                                           last five years
  BP    Last systolic BP                  133.1   17.69     534 (52%)
        Average of last three systolic
                                          133.6   15.54     464
        BP results                                                (45%)
        Last diastolic BP                  82.3   11.84     533 (52%)
        Average of last three diastolic
                                           82.1   10.28     462
        BP results                                                (45%)
HbA1c Last HbA1c in DCCT-aligned                            188 (18%)
                                            7.1    2.03
      (%)
        Last HbA1c in IFCC-                                  78   (8%)
                                           63.6   26.24
        standardised (mmol/mol)
Last Total-to-HDL cholesterol ratio        4.94    1.02     218 (21%)
Last BMI                                   33.6    6.60     400 (39%)
66% 35+ in Group 1 & 2
Feedback from participating clinicians

 Enthusiasm for studies addressing the
  needs of PI wrt BP management
 Acceptance of structured care models
 Understanding PI
 Lack of resources and capacity
  – CDM nurse
  – Minimize disruption to existing services
Conclusions – so far

 • Not a RCT
 • Feasibility study
 • A lot of data is already there
   – It can reveal opportunities for
     process improvement
 • Going to scale with CDM
   – Opportunities and challenges
Acknowledgements

 • The Caring Does Matter Initiative is funded by
   the Ministry of Health’s Pacific Grant Fund.
 • We would also like to thank the West Fono
   management and staff, esp. Mr. Tevita Funaki
   Mr. Anthony Tuitahi, and Ms Tai Boyce for
   supporting the program.
 • We extend our thanks to the staff of
   participating general practices for
   accommodating the study.
 Further info: h.gu@auckland.ac.nz

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The Caring Does Matter (CDM) Initiative: To Improve Cardiovascular Medication Adherence in Pacific People

  • 1. The Caring Does Matter (CDM) Initiative: To Improve Cardiovascular Medication Adherence in Pacific People Jim Warren, Yulong Gu (Helen), John Kennelly The National Institute for Health Innovation
  • 2. Why the interest? • Burning platform – Increased rates of chronic illness – Ageing population – Cost / workforce / delivery meltdown! – Even if we were satisfied with current quality of health delivery, it’s not sustainable • Long-term conditions as the target • Lots of data – Computerisation naturally lays down data, which can be used to improve patient management
  • 3. Chronic conditions, esp. anything ‘vascular’ • Amenable (and interesting) for analysis of long sequences in transactional electronic health records (EHRs) • E.g. blood pressure (BP) is a huge risk factor – CVD risk doubles for every 20/10 mm Hg • Also implicated in kidney failure – Very controllable with medication – Several classes of medication with different side- effects and benefits/indications (makes it interesting!) • Statins/cholesterol and blood sugar control also very relevant
  • 4. CDM Initiative • A feasibility study – Structured care, based on West Fono program • To identify and intervene on suboptimal management of CVR – Medication adherence gaps - MPR
  • 5. How to identify intervention targets? • Demographics • CVR scores • Prescriptions
  • 6. Pacific adults (20+) grouped into 4:  having high CVR risk (>=10%) and low MPR (<80%)  having no CVR screening recorded in the last five years and aged 35 or over  having high CVR risk (>=10%) but MPR OK (>=80%)  having low CVR risk (<10%) or having no CVR screening recorded in the last five years but being younger than 35
  • 7. Group 1 Patient List example Pt Age Gen- Eth- Anti- Oral Last CVR ID der nicity hypertensives Cholesterol Diabetes screening CVR medications date 1 64 M Tongan None <80% None 30-Sep-11 99 2 60 F Samoan OK OK <80% 13-Mar-12 99 3 51 M Samoan None <80% None 6-Sep-11 99 Other 4 81 M OK None <80% 11-Nov-11 30 Pacific 5 63 M Samoan <80% Recent start None 19-Oct-11 22 6 62 M Samoan <80% None None 14-Apr-12 22 7 65 M Samoan <80% <80% <80% 10-Jan-12 21 8 63 M Samoan <80% <80% <80% 17-Jul-11 18 9 58 F Samoan <80% None None 16-May-12 16 10 63 M Fijian None None None 22-Jul-09 15 …
  • 8. 9,128 Pacific adults in 10 clinics Clinics Practice Pacific patient Pacific patient Pacific patient ID patient population # (% in total population population population # practice population) 20+ # 35+ # A 6884 5144 (75%) 3060 2001 B 12984 1872 (14%) 1038 627 C 5696 1634 (29%) 934 600 D 11939 1481 (12%) 764 470 E 4794 1355 (28%) 726 471 F 5863 1316 (22%) 702 438 G 13112 1114 (8%) 610 384 H 1564 1103 (71%) 669 429 I 4875 583 (12%) 331 194 J 9633 534 (16%) 294 171 Total: 77344 16136 (21%) 9128 5785
  • 9. 1,021 with high CVR & low MPR Practice High CVR & low MPR # (% No CVR & 35+ # (% in ID in Pacific 20+ at the clinics) Pacific 35+) A 522 (17%) 855 (43%) B 67 (6%) 370 (59%) C 91 (10%) 297 (50%) D 58 (8%) 293 (62%) E 61 (8%) 207 (44%) F 50 (7%) 272 (62%) G 55 (9%) 195 (51%) H 71 (11%) 157 (37%) I 29 (9%) 51 (26%) J 17 (6%) 115 (67%) Total: 1021 (11%) 2812 (49%)
  • 10. CVR profile of Group 1 99 45-49 14% 40-44 0% 35-39 0% 3% 30-34 1% 25-29 10-14 4% 43% 20-24 10% 15-19 25%
  • 11. Physiological profile of Group 1 Measurements Mean Standard Pt # (%) deviation measured in last five years BP Last systolic BP 133.1 17.69 534 (52%) Average of last three systolic 133.6 15.54 464 BP results (45%) Last diastolic BP 82.3 11.84 533 (52%) Average of last three diastolic 82.1 10.28 462 BP results (45%) HbA1c Last HbA1c in DCCT-aligned 188 (18%) 7.1 2.03 (%) Last HbA1c in IFCC- 78 (8%) 63.6 26.24 standardised (mmol/mol) Last Total-to-HDL cholesterol ratio 4.94 1.02 218 (21%) Last BMI 33.6 6.60 400 (39%)
  • 12. 66% 35+ in Group 1 & 2
  • 13. Feedback from participating clinicians  Enthusiasm for studies addressing the needs of PI wrt BP management  Acceptance of structured care models  Understanding PI  Lack of resources and capacity – CDM nurse – Minimize disruption to existing services
  • 14. Conclusions – so far • Not a RCT • Feasibility study • A lot of data is already there – It can reveal opportunities for process improvement • Going to scale with CDM – Opportunities and challenges
  • 15. Acknowledgements • The Caring Does Matter Initiative is funded by the Ministry of Health’s Pacific Grant Fund. • We would also like to thank the West Fono management and staff, esp. Mr. Tevita Funaki Mr. Anthony Tuitahi, and Ms Tai Boyce for supporting the program. • We extend our thanks to the staff of participating general practices for accommodating the study. Further info: h.gu@auckland.ac.nz

Editor's Notes

  1. Good afternoon, my name is Helen