Getting high by taking too much cannabis is common. Learn how long a cannabis high last and how to sober up quickly. Visit medicalmarijuanacardanaheim.com
Differences between cannabis flowers and ediblesintlcannabiscorp
There are lots of cannabis-infused foods produced through marijuana production techniques including bacon, hummus, candies, muffins, and many others. As you explore much about this world of marijuana, you will find yourself wondering what to expect from these edibles.
You Took a Weed Tolerance Break But Still Can't Get High?Evergreen Buzz
You took a marijuana break and it didn't work, now what https://cannabis.net/blog/how-to/you-took-a-tolerance-break-from-cannabis-but-still-cant-get-high-now-what
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Objectives
Identify the symptoms of marijuana intoxication
Review the research related to the short and long term effects of marijuana on the brain and body
Explore the medical uses of marijuana
Discuss marijuana as a gateway drug
What is It
Marijuana refers to the dried leaves, flowers, stems, and seeds from the hemp plant, Cannabis sativa.
The plant contains the mind-altering chemical delta-9-tetrahydrocannabinol (THC)
Extracts with high amounts of THC can also be made from the cannabis plant
How is it Used
Smoked
Joints
Pipes or water pipes (bongs)
Blunts—emptied cigars that have been partly or completely refilled with marijuana.
Vaporized
Pull the active ingredients from the marijuana and collect their vapor in a storage unit which is inhaled instead of smoke.
Eaten: Brownies, cookies, or candy, or brew it as a tea.
How is it Used
Resins: A newly popular method of use is smoking or eating different forms of THC-rich resins
Smoking THC-rich resins extracted from the marijuana plant is on the rise. Users call this practice dabbing. People are using various forms of these extracts, such as:
hash oil or honey oil—a gooey liquid
wax or budder—a soft solid with a texture like lip balm
shatter—a hard, amber-colored solid
Oral Ingestion
Orally consumed cannabinoids tends to be stronger and last longer (4-6 hours) than inhaled cannabis.
This is because of the way bodies metabolize THC.
When cannabis is inhaled, THC passes rapidly from the lungs to the blood stream and to the brain.
When cannabis is consumed orally, a significant portion of THC is converted into the metabolite 11-hydroxy-THC before reaching the brain.
This metabolite is believed to be slightly more potent than THC and possesses a greater blood-brain penetrability
Short Term Effects
THC effects are felt more slowly when the person eats or drinks it. (30 minutes to 1 hour)
Effects
Altered senses (for example, seeing brighter colors)
Temporary hallucinations
Altered sense of time
Changes in mood
Impaired body movement
Difficulty with thinking and problem-solving
Impaired memory
Breathing problems. Marijuana smoke irritates the lungs
Increased heart rate for up to 3 hours after smoking
Is CBD addictive? Does it make you high? To put it short — no, CBD is not addictive. But let's dig deeper and learn why in our recent research. We look at the scientific proof of why CBD is not addictive. And the legislative point of view, which is also backed up by science. In our article, you can learn about the nature of addiction, and understand why we crave some things more than others. Take a look!
Differences between cannabis flowers and ediblesintlcannabiscorp
There are lots of cannabis-infused foods produced through marijuana production techniques including bacon, hummus, candies, muffins, and many others. As you explore much about this world of marijuana, you will find yourself wondering what to expect from these edibles.
You Took a Weed Tolerance Break But Still Can't Get High?Evergreen Buzz
You took a marijuana break and it didn't work, now what https://cannabis.net/blog/how-to/you-took-a-tolerance-break-from-cannabis-but-still-cant-get-high-now-what
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Objectives
Identify the symptoms of marijuana intoxication
Review the research related to the short and long term effects of marijuana on the brain and body
Explore the medical uses of marijuana
Discuss marijuana as a gateway drug
What is It
Marijuana refers to the dried leaves, flowers, stems, and seeds from the hemp plant, Cannabis sativa.
The plant contains the mind-altering chemical delta-9-tetrahydrocannabinol (THC)
Extracts with high amounts of THC can also be made from the cannabis plant
How is it Used
Smoked
Joints
Pipes or water pipes (bongs)
Blunts—emptied cigars that have been partly or completely refilled with marijuana.
Vaporized
Pull the active ingredients from the marijuana and collect their vapor in a storage unit which is inhaled instead of smoke.
Eaten: Brownies, cookies, or candy, or brew it as a tea.
How is it Used
Resins: A newly popular method of use is smoking or eating different forms of THC-rich resins
Smoking THC-rich resins extracted from the marijuana plant is on the rise. Users call this practice dabbing. People are using various forms of these extracts, such as:
hash oil or honey oil—a gooey liquid
wax or budder—a soft solid with a texture like lip balm
shatter—a hard, amber-colored solid
Oral Ingestion
Orally consumed cannabinoids tends to be stronger and last longer (4-6 hours) than inhaled cannabis.
This is because of the way bodies metabolize THC.
When cannabis is inhaled, THC passes rapidly from the lungs to the blood stream and to the brain.
When cannabis is consumed orally, a significant portion of THC is converted into the metabolite 11-hydroxy-THC before reaching the brain.
This metabolite is believed to be slightly more potent than THC and possesses a greater blood-brain penetrability
Short Term Effects
THC effects are felt more slowly when the person eats or drinks it. (30 minutes to 1 hour)
Effects
Altered senses (for example, seeing brighter colors)
Temporary hallucinations
Altered sense of time
Changes in mood
Impaired body movement
Difficulty with thinking and problem-solving
Impaired memory
Breathing problems. Marijuana smoke irritates the lungs
Increased heart rate for up to 3 hours after smoking
Is CBD addictive? Does it make you high? To put it short — no, CBD is not addictive. But let's dig deeper and learn why in our recent research. We look at the scientific proof of why CBD is not addictive. And the legislative point of view, which is also backed up by science. In our article, you can learn about the nature of addiction, and understand why we crave some things more than others. Take a look!
2024 Numerator Consumer Study of Cannabis UsageNeil Kimberley
Numerator is a unique quantative research company that creates consumer behavior insights from retail purchases. This study explores the consumer behavior of consumers who purchase Cannabis and CBD in the USA.
Medical Marijuana and Clinical Oncology in 2022"The Good the Bad and the Potentially Ugly"
Marijuana/cannabinoids are particularly appealing for oncology patients offering the possibility of a single medication to encompass a variety of problems, such as pain, nausea, anorexia, sleep disorders , and anxiety.
Dr. Malcolm Brigden - University of Calgary - Canada.
Lesson B9.pdfLesson B.9 Dr. W.J. Racz CANNA.docxSHIVA101531
Lesson B9.pdf
Lesson B.9 Dr. W.J. Racz
CANNABIS
Reference: A Primer of Drug Action, 12
th
ed.
Objectives
At the conclusion of this lesson, you should be able to: (1) describe the history of cannabis use,
(2) state the mechanism of action of the cannabinoids, (3) state the time of onset and duration of
response to smoking marijuana, (4) list the accepted medical and proposed medical uses of the
cannabinoids, (5) describe the effects of short-term, low-dose and high-dose use of cannabis, (6)
describe the effects of chronic high-dose use of cannabis, and (7) describe the degree and type of
tolerance and dependence associated with cannabis.
Introduction
The term “cannabis” refers to the drug-containing forms of the hemp plant, Cannabis sativa,
which is an herbaceous annual. There are two varieties of Cannabis sativa – resin-producing and
fibre-producing. In Cannabis sativa, there are 420 chemical compounds, many of which are
common to other plants. There are 60 compounds that are found only in Cannabis sativa, and
these compounds are referred to as cannabinoids. Of these compounds, l-trans-Δ
9
-
tetrahydrocannabinol (THC) is the most potent psychoactive agent in cannabis, and THC
accounts for most, but not all, of the psychoactive effects of cannabis. Common names for
cannabis or its products include marijuana, hashish, hashish oil, charas, bhang, ganja, and dagga.
Marijuana, hashish and hashish oil are the cannabis preparations most common to North
America.
History
2700 BC – 1800’s Cannabis plant was used for manufacturing rope; marijuana was used for
its mild intoxicating effects as it was considered less harmful than alcohol.
1920’s – 1930’s Public concern was raised over the effects of marijuana on individuals and
society (“menace of marijuana”). Legislation was enacted to outlaw the
use of marijuana, which was considered to be a narcotic.
1960’s – 1970’s Increased use of cannabis, primarily in the form of marijuana. Survey in
1972: more than two million people in the U.S.A. reported daily use of
marijuana. Survey in 1977: 60% of young adults in the U.S.A. reported
some experience (?) with marijuana. A 1979 survey in Ontario revealed
that approximately 50% of students aged 16 or over reported some use of
marijuana in the preceding 12 months.
1978 U.S.A.-sponsored project using the herbicide, paraquat, was initiated in an
Lesson B.9 CANNABIS
______________________________________________________________________________
2
attempt to destroy cannabis crops in Mexico. It failed. U.S.A. citizens
were smoking cannabis products containing paraquat, which can produce
lung toxicity.
1980’s In the early 1980’s, the use of marijuana began to stabilize. In 1982, 42%
of high school students in the U.S.A. reported use of the drug in the
previous year and 5.5% used it daily. The figures in Ontario were similar.
1990’s ...
With an MMJ Card aforementioned list contains a vast variety of ways to consume CBD. In case, if some methods cannot deliver desired results then you can try cannabutter, chewing gum, canna oil, THC Soda, Cannabis syrup, and THC bath soaks, etc. Visit : https://www.medicalmarijuanacardriverside.com/blog/a-420-med-evaluations-guide-on-different-forms-of-cannabis-consumption/
If you are subject to DOT Reasonable Suspicion Testing in your workplace, using CBD oil could potentially put you at risk of testing positive for THC, which is a prohibited substance under DOT regulations. CBD oil can contain trace amounts of THC, and the amount of THC in the product can vary depending on the source and manufacturing process.
Even though CBD oil is legal at the federal level, DOT has not approved the use of CBD products, including CBD oil, for safety-sensitive employees subject to drug testing. Therefore, if you test positive for THC, you could face disciplinary action or termination of employment.
It is essential to consult with your healthcare provider and employer's policies on CBD oil usage before using any CBD products, especially if you are subject to DOT Reasonable Suspicion Testing. If you are looking for an alternative to CBD oil, you may consider using other over-the-counter medications or prescription drugs approved by the DOT.
CBD products have flooded the marketplace since 2018, when the federal government legalized cannabis based products containing less than 0.3% THC (tetrahydrocannabinol.) This small amount of THC won’t produce a high. The problem: CBD products are unregulated, so there is no way to know if the THC level is above the legal limit. This means THC might be detected by a drug test if you CBD heavily and it builds up in your body, or the product used contains large amount of THC
So, It’s Complicated
The legalization of medical marijuana in many states and recreational weed in others complicates the issue for employees and employers. The federal government still considers marijuana or any product containing more than 0.3% THC illegal. (As a side note, the American Medical Association (AMA) still does not support the legalization of cannabis containing THC for the purpose of treating any disease or medical condition, although it does encourage ongoing research.)
Here is what you need to consider before using any CBD and THC-containing cannabis products so that you do not jeopardize your employment situation.
What Is CBD, and Is It Legal?
CBD oil can be purchased in many forms, including oil, capsules, spray, creams, tablets, food and drink. CBD oil is derived from a hemp variety of cannabis, which is low in THC, the marijuana compound that makes people high. CBD products containing less than 0.3% THC are legal under federal law. CBD is short for cannabidiol.
What Are the Benefits of Using CBD?
Patients use CBD to treat pain, anxiety, sleep issues, and other conditions. However, research on the drug’s effectiveness for those and other conditions is limited. Studies are continuing into its benefits and possible uses for CBD. However, some users claim little or no benefit from using CBD oil.
Why Should You Be Concerned If You Use CBD?
The Food and Drug Administration has approved only one CBD product, a prescription drug that treats seizures.
Looking to explore the world of cannabis and all its exciting possibilities? If so, you won't want to miss out on this informative and engaging ebook all about cannabis distillate!
Packed with everything you need to know about this highly potent and versatile cannabis product, this ebook covers the history, production, benefits, and risks of cannabis distillate in detail, providing readers with a comprehensive guide to this fascinating topic.
Whether you're a seasoned cannabis enthusiast or just getting started, this ebook is the perfect resource for anyone interested in learning more about cannabis distillate and its many uses. So why wait? Download your copy today and start exploring the world of cannabis distillate like never before!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
2024 Numerator Consumer Study of Cannabis UsageNeil Kimberley
Numerator is a unique quantative research company that creates consumer behavior insights from retail purchases. This study explores the consumer behavior of consumers who purchase Cannabis and CBD in the USA.
Medical Marijuana and Clinical Oncology in 2022"The Good the Bad and the Potentially Ugly"
Marijuana/cannabinoids are particularly appealing for oncology patients offering the possibility of a single medication to encompass a variety of problems, such as pain, nausea, anorexia, sleep disorders , and anxiety.
Dr. Malcolm Brigden - University of Calgary - Canada.
Lesson B9.pdfLesson B.9 Dr. W.J. Racz CANNA.docxSHIVA101531
Lesson B9.pdf
Lesson B.9 Dr. W.J. Racz
CANNABIS
Reference: A Primer of Drug Action, 12
th
ed.
Objectives
At the conclusion of this lesson, you should be able to: (1) describe the history of cannabis use,
(2) state the mechanism of action of the cannabinoids, (3) state the time of onset and duration of
response to smoking marijuana, (4) list the accepted medical and proposed medical uses of the
cannabinoids, (5) describe the effects of short-term, low-dose and high-dose use of cannabis, (6)
describe the effects of chronic high-dose use of cannabis, and (7) describe the degree and type of
tolerance and dependence associated with cannabis.
Introduction
The term “cannabis” refers to the drug-containing forms of the hemp plant, Cannabis sativa,
which is an herbaceous annual. There are two varieties of Cannabis sativa – resin-producing and
fibre-producing. In Cannabis sativa, there are 420 chemical compounds, many of which are
common to other plants. There are 60 compounds that are found only in Cannabis sativa, and
these compounds are referred to as cannabinoids. Of these compounds, l-trans-Δ
9
-
tetrahydrocannabinol (THC) is the most potent psychoactive agent in cannabis, and THC
accounts for most, but not all, of the psychoactive effects of cannabis. Common names for
cannabis or its products include marijuana, hashish, hashish oil, charas, bhang, ganja, and dagga.
Marijuana, hashish and hashish oil are the cannabis preparations most common to North
America.
History
2700 BC – 1800’s Cannabis plant was used for manufacturing rope; marijuana was used for
its mild intoxicating effects as it was considered less harmful than alcohol.
1920’s – 1930’s Public concern was raised over the effects of marijuana on individuals and
society (“menace of marijuana”). Legislation was enacted to outlaw the
use of marijuana, which was considered to be a narcotic.
1960’s – 1970’s Increased use of cannabis, primarily in the form of marijuana. Survey in
1972: more than two million people in the U.S.A. reported daily use of
marijuana. Survey in 1977: 60% of young adults in the U.S.A. reported
some experience (?) with marijuana. A 1979 survey in Ontario revealed
that approximately 50% of students aged 16 or over reported some use of
marijuana in the preceding 12 months.
1978 U.S.A.-sponsored project using the herbicide, paraquat, was initiated in an
Lesson B.9 CANNABIS
______________________________________________________________________________
2
attempt to destroy cannabis crops in Mexico. It failed. U.S.A. citizens
were smoking cannabis products containing paraquat, which can produce
lung toxicity.
1980’s In the early 1980’s, the use of marijuana began to stabilize. In 1982, 42%
of high school students in the U.S.A. reported use of the drug in the
previous year and 5.5% used it daily. The figures in Ontario were similar.
1990’s ...
With an MMJ Card aforementioned list contains a vast variety of ways to consume CBD. In case, if some methods cannot deliver desired results then you can try cannabutter, chewing gum, canna oil, THC Soda, Cannabis syrup, and THC bath soaks, etc. Visit : https://www.medicalmarijuanacardriverside.com/blog/a-420-med-evaluations-guide-on-different-forms-of-cannabis-consumption/
If you are subject to DOT Reasonable Suspicion Testing in your workplace, using CBD oil could potentially put you at risk of testing positive for THC, which is a prohibited substance under DOT regulations. CBD oil can contain trace amounts of THC, and the amount of THC in the product can vary depending on the source and manufacturing process.
Even though CBD oil is legal at the federal level, DOT has not approved the use of CBD products, including CBD oil, for safety-sensitive employees subject to drug testing. Therefore, if you test positive for THC, you could face disciplinary action or termination of employment.
It is essential to consult with your healthcare provider and employer's policies on CBD oil usage before using any CBD products, especially if you are subject to DOT Reasonable Suspicion Testing. If you are looking for an alternative to CBD oil, you may consider using other over-the-counter medications or prescription drugs approved by the DOT.
CBD products have flooded the marketplace since 2018, when the federal government legalized cannabis based products containing less than 0.3% THC (tetrahydrocannabinol.) This small amount of THC won’t produce a high. The problem: CBD products are unregulated, so there is no way to know if the THC level is above the legal limit. This means THC might be detected by a drug test if you CBD heavily and it builds up in your body, or the product used contains large amount of THC
So, It’s Complicated
The legalization of medical marijuana in many states and recreational weed in others complicates the issue for employees and employers. The federal government still considers marijuana or any product containing more than 0.3% THC illegal. (As a side note, the American Medical Association (AMA) still does not support the legalization of cannabis containing THC for the purpose of treating any disease or medical condition, although it does encourage ongoing research.)
Here is what you need to consider before using any CBD and THC-containing cannabis products so that you do not jeopardize your employment situation.
What Is CBD, and Is It Legal?
CBD oil can be purchased in many forms, including oil, capsules, spray, creams, tablets, food and drink. CBD oil is derived from a hemp variety of cannabis, which is low in THC, the marijuana compound that makes people high. CBD products containing less than 0.3% THC are legal under federal law. CBD is short for cannabidiol.
What Are the Benefits of Using CBD?
Patients use CBD to treat pain, anxiety, sleep issues, and other conditions. However, research on the drug’s effectiveness for those and other conditions is limited. Studies are continuing into its benefits and possible uses for CBD. However, some users claim little or no benefit from using CBD oil.
Why Should You Be Concerned If You Use CBD?
The Food and Drug Administration has approved only one CBD product, a prescription drug that treats seizures.
Looking to explore the world of cannabis and all its exciting possibilities? If so, you won't want to miss out on this informative and engaging ebook all about cannabis distillate!
Packed with everything you need to know about this highly potent and versatile cannabis product, this ebook covers the history, production, benefits, and risks of cannabis distillate in detail, providing readers with a comprehensive guide to this fascinating topic.
Whether you're a seasoned cannabis enthusiast or just getting started, this ebook is the perfect resource for anyone interested in learning more about cannabis distillate and its many uses. So why wait? Download your copy today and start exploring the world of cannabis distillate like never before!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
Got Too High? Follow These Quick Tips to Sober up Fast
1. Got Too High? Follow
These Quick Tips to
Sober up Fast
2. In recent years, marijuana use among
patients with various conditions is
getting popular. In a legalized state
like California, you can easily access it
from licensed dispensaries with
a .medical cannabis card online
3. THC – A Psychoactive
Cannabinoid
THC (tetrahydrocannabinol) is
a cannabis cannabinoid. It’s
responsible for causing high
effects associated with
marijuana use.
4. How Long Cannabis
High Lasts?
Usually, it lasts from 2 to 10
hours. However, how long you
experience the high effects
depend on various factors-
6. Dosage
Dosing is important, especially
when you taking edibles or
trying a new strain. The
amount you take makes a
great difference.
7. Type of Strains
Consumed
The higher the potency of
cannabis, the longer the high
effects last. Different cannabis
strains contain different levels
of THC, CBD, and other
cannabinoids.
8. Other Factors
Different consumers receive
different effects from cannabis
use. This is because every
person’s body processes
substances differently.
9. What’s The Solution?
When you feel too high, which
make you uncomfortable,
follow these quick sober up
methods-
10. Relax
Firstly, sit on the couch and
relax. Drink some water.
Cannabis high isn’t something
that lasts forever. Also, you can
counteract its effects.
11. Go to Sleep
Find a quiet place in your
home, and sleep. Stay calm,
and take deep breaths
through the nose, and breathe
out through the mouth.
12. Try CBD
CBD is a non-psychoactive
compound, which can help
you counteract the THC
effects. The major difference is
the type of cannabinoid
receptors they interact with.
13. Key Takeaways
Experiencing high by
consuming too much
cannabis is common. And, you
need not panic as the effects
don’t last forever.