This presentation was delivered at the Global Forum 2019 in Africa Panel Discussion by Lin Roger Li, Senior Manager, Strategic Sourcing, Sourcing and Supply Chain Department at the Global Fund.
Supply Chain Challenges in Light of Environmental Sustainability - Global For...UN SPHS
This presentation was delivered at the Global Forum 2019 in Africa Panel Discussion by Dorothy Amony, Product Quality Officer, Global Drug Facility Team.
Sustainable Procurement Index for Health (SPIH) - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa session on Sustainable Procurement Index for Health by Dr. Kristian Steele and Anna Tuddenham of Arup.
Water and Pharmaceuticals - Global Forum 2019 in AfricaUN SPHS
his presentation was delivered at the Global Forum 2019 in Africa parallel session on Water Management Pharmaceuticals in the Environment (PiE) / Antimicrobial Resistance (AMR) by Iris Cherry Panorel, Programme Officer, SIWI.
The Case of MTTS Asia - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa parallel session on Business Ethics by Love Potya, East Africa Regional Director, Medical Technology Transfer and Services (MTTS) and Day One Health.
http://bit.ly/AfricaForum2019
Ethical Considerations and Anti-Corruption Agenda - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa parallel session on Business Ethics by Santie Roy, Western Cape.
http://bit.ly/AfricaForum2019
17 -21 June 2019. Minna, Nigeria. Inaugural Meeting of Stakeholders, Africa Centre of Excellence for Mycotoxin and Food Safety.
Presentation by Habiba Hassan-Wassef, MD
National Research Center, Cairo
Supply Chain Challenges in Light of Environmental Sustainability - Global For...UN SPHS
This presentation was delivered at the Global Forum 2019 in Africa Panel Discussion by Dorothy Amony, Product Quality Officer, Global Drug Facility Team.
Sustainable Procurement Index for Health (SPIH) - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa session on Sustainable Procurement Index for Health by Dr. Kristian Steele and Anna Tuddenham of Arup.
Water and Pharmaceuticals - Global Forum 2019 in AfricaUN SPHS
his presentation was delivered at the Global Forum 2019 in Africa parallel session on Water Management Pharmaceuticals in the Environment (PiE) / Antimicrobial Resistance (AMR) by Iris Cherry Panorel, Programme Officer, SIWI.
The Case of MTTS Asia - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa parallel session on Business Ethics by Love Potya, East Africa Regional Director, Medical Technology Transfer and Services (MTTS) and Day One Health.
http://bit.ly/AfricaForum2019
Ethical Considerations and Anti-Corruption Agenda - Global Forum 2019 in AfricaUN SPHS
This presentation was delivered at the Global Forum 2019 in Africa parallel session on Business Ethics by Santie Roy, Western Cape.
http://bit.ly/AfricaForum2019
17 -21 June 2019. Minna, Nigeria. Inaugural Meeting of Stakeholders, Africa Centre of Excellence for Mycotoxin and Food Safety.
Presentation by Habiba Hassan-Wassef, MD
National Research Center, Cairo
Safe Food, Fair Food for Cambodia task force: Research to policy and practiceILRI
Presentation by Hung Nguyen-Viet, Sothyra Tum, Chhay Ty, Melissa Young and Delia Grace at the Safe Food, Fair Food for Cambodia project final workshop, Phnom Penh, Cambodia, 21-22 June 2021.
LIVES dairy value chain development: Distinguishing between fluid milk and bu...ILRI
Presented by Dirk Hoekstra, Azage Tegegne, Berhanu Gebremedhin, Aklilu Bogale and Yasin Getahun at the 21st Annual Conference of Ethiopian Society of Animal Production (ESAP), Addis Ababa, 28-30 August 2013
Safe Food, Fair Food for Cambodia: Scaling opportunitiesILRI
Presentation Hung Nguyen-Viet, Sothyra Tum, Chhay Ty, Melissa Young and Delia Grace at the Safe Food, Fair Food for Cambodia project final workshop, Phnom Penh, Cambodia, 21-22 June 2021.
Agrifood; a new Multi-Criteria Decision Analysis tool to examine trade-offs i...Francois Stepman
24 - 29 June 2019. Hyderabad, India. The ANH Academy Week is a series of annual events that bring together the community of researchers and users of research (practitioners and policymakers) working at the intersection of agriculture, nutrition and health.
How to tackle chemicals of high concern in products – The construction Sector as a case study. Stylianos Kephalopoulos, Leader of Competence Group Exposure, European Commission – Joint Research Centre
PANEL 5: Substances of concern (SVHCs) in products – whose job is it to control these in a free trade world? - Kevin Mulvaney, Senior Director, ACC, USA
The Brazilian Path to Establish Legal and Administrative Infrastructure to th...MyChemicalMonitoring
Presentation from Letícia Reis de Carvalho,
Director at the Departament of Environmental Quality in the industry
Ministry of the Environment, at the ICCM4 (September/October 2015)
The Global Fund- SPHS Engagement: Responsible Procurement FrameworkUN SPHS
The Global Fund and SPHS will solicit comments and advice on the project, and will collect any relevant experiences that the SPHS members can share from efforts to implement responsible/sustainable procurement practices. Deloitte will also prepare some questions to help focus the discussions.
The recording of the webinar is available here: https://drive.google.com/file/d/1BIYLDyOMVfbcsIzOB-5hfY7FBbI3ZLzh/view
Accelerating uptake of research on sustainable livestock interventions—Insigh...ILRI
Presented by Amos Omore, ILRI, at the CGIAR Livestock CRP and GASL joint side event on national partnerships for sustainable livestock systems at the 7th All-Africa Conference on Animal Agriculture, Accra, Ghana, 30 July 2019
Safe Food, Fair Food for Cambodia task force: Research to policy and practiceILRI
Presentation by Hung Nguyen-Viet, Sothyra Tum, Chhay Ty, Melissa Young and Delia Grace at the Safe Food, Fair Food for Cambodia project final workshop, Phnom Penh, Cambodia, 21-22 June 2021.
LIVES dairy value chain development: Distinguishing between fluid milk and bu...ILRI
Presented by Dirk Hoekstra, Azage Tegegne, Berhanu Gebremedhin, Aklilu Bogale and Yasin Getahun at the 21st Annual Conference of Ethiopian Society of Animal Production (ESAP), Addis Ababa, 28-30 August 2013
Safe Food, Fair Food for Cambodia: Scaling opportunitiesILRI
Presentation Hung Nguyen-Viet, Sothyra Tum, Chhay Ty, Melissa Young and Delia Grace at the Safe Food, Fair Food for Cambodia project final workshop, Phnom Penh, Cambodia, 21-22 June 2021.
Agrifood; a new Multi-Criteria Decision Analysis tool to examine trade-offs i...Francois Stepman
24 - 29 June 2019. Hyderabad, India. The ANH Academy Week is a series of annual events that bring together the community of researchers and users of research (practitioners and policymakers) working at the intersection of agriculture, nutrition and health.
How to tackle chemicals of high concern in products – The construction Sector as a case study. Stylianos Kephalopoulos, Leader of Competence Group Exposure, European Commission – Joint Research Centre
PANEL 5: Substances of concern (SVHCs) in products – whose job is it to control these in a free trade world? - Kevin Mulvaney, Senior Director, ACC, USA
The Brazilian Path to Establish Legal and Administrative Infrastructure to th...MyChemicalMonitoring
Presentation from Letícia Reis de Carvalho,
Director at the Departament of Environmental Quality in the industry
Ministry of the Environment, at the ICCM4 (September/October 2015)
The Global Fund- SPHS Engagement: Responsible Procurement FrameworkUN SPHS
The Global Fund and SPHS will solicit comments and advice on the project, and will collect any relevant experiences that the SPHS members can share from efforts to implement responsible/sustainable procurement practices. Deloitte will also prepare some questions to help focus the discussions.
The recording of the webinar is available here: https://drive.google.com/file/d/1BIYLDyOMVfbcsIzOB-5hfY7FBbI3ZLzh/view
Accelerating uptake of research on sustainable livestock interventions—Insigh...ILRI
Presented by Amos Omore, ILRI, at the CGIAR Livestock CRP and GASL joint side event on national partnerships for sustainable livestock systems at the 7th All-Africa Conference on Animal Agriculture, Accra, Ghana, 30 July 2019
Webinar presentation on the United Nations initiative on Sustainable Procurem...UN SPHS
Webinar presentation on United Nations initiative on Sustainable Procurement in the Health Sector (SPHS), joined by SPHS, UNDP and UNFPA, hosted by UNEP
Conference with Ukrainian Healthcare Procurement ExpertsUN SPHS
Dr. Rosemary Kumwenda, UNDP Senior Advisor to Health and HIV Sustainable Responses and Mirjana Milic, UNDP Associate Coordinator delivered a presentation about the UNDP approach to sustainable health procurement
SPHS Webinar: Ensuring Fair Play in the Global Health Supply Chains UN SPHS
This first United Nations informal Inter Agency Task Team webinar on Sustainable Procurement in the Health Sector (SPHS) is relevant to all those active in the healthcare supply chain - from producers to purchasers. In particular, it is aimed at assisting procurement teams planning to institute sustainability initiatives to think through how they can include a wide diversity of suppliers in these sustainability initiatives. It explains the benefits of ensuring actions which are inclusive of all, allowing small and medium enterprises to meet new standards. It also covers supplier development and how procuring entities can engage with suppliers and manufacturers to understand the challenges they face and how they can work jointly to identify opportunities to integrate sustainability in the supply chain.
UNDP Sustainable Health Procurement Policy and PracticeUN SPHS
On 27th March 2017, Dr. Rosemary Kumwenda, UNDP HIV, Health, and Development EECA Regional Team Leader and the SPHS Secretariat Coordinator, delivered a presentation about the work of SPHS Task Team, key procurement criteria developed, supplier engagement and approach to integrating sustainability into UN procurement.
Craig Chester from Fairtrade Australia presented at the UNAA Sustainable Consumption and Production Seminar held on 27 June 2013 hosted by Russell Kennedy, Melbourne.
Held in support of the United Nations 10 Year Framework of Programmes on Sustainable Consumption and Production Patterns, the seminar brought together experts and practitioners from across business, government and civil society to provide a platform for shared learning on integrating sustainable consumption and production measures throughout business operations, relationships and value chains.
Guest Speakers and Panelists:
- Tim Grant, Director, Life Cycle Strategies
- Joshua Bishop, National Manager – Markets, Sustainability and Business Partnerships, WWF Australia
- Craig Chester, Operations Manager Australia, Fairtrade Australia and New Zealand
- Liam Smith, Director, BehaviourWorks Australia, Monash Sustainability Institute
- Clinton Squires, Australian Managing Director, Interface
More information available at: http://www.unaavictoria.org.au/education-advocacy/masterclasses/sustainable-consumption-and-production-seminar/
The XII Healthy Hospitals Seminar (Seminário Hospitais Saudáveis - SHS 2019)UN SPHS
This presentation was delivered by Dr. Rosemary Kumwenda (UNDP Team Leader for HIV, Health and Development in Eastern Europe & Central Asia and SPHS Coordinator) at the XII Healthy Hospitals Seminar 2019 (SHS Seminar 2019) which took place on 11-12 November 2019 in São Paulo – Brazil.
The overall theme of SHS 201 is, “Health for Climate: Leading Sustainable, Low-Carbon Supply Chains,” and aims to highlight conscious and sustainable consumption as a central strategy for tackling climate change. In this sense, the health sector, as a major consumer of production inputs, natural resources and technologies, has an important role to play, leading the transformation of all supply chains into the necessary transition to a low carbon economy.
The vital interconnections between health, oceans and climate changeUN SPHS
Dr. Richard Hixson (Consultant in Clinical Care Medicine and Co-Founder of Healthcare Ocean) at the 5h Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Resilient Circular Economy Medical Textile SolutionsUN SPHS
Dr. Tom Dawson
(Founder, Revolution-ZERO and Visiting Research Fellow in Healthcare Circular Economics, University of Exeter) at the 5th Saving Lives Sustainably Global Forum 2022 on 24 November 2022.
Clara Inés Meneses Sandoval (Environmental Management Coordinator, Fundación Club Noel, Colombia) at the 5h Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Pablo Tobón Uribe Hospital Strategy in the reuse of personal protection eleme...UN SPHS
Ana Zoraida Gomez Diaz (Director, Department of General Services and Environmental Management Hospital Pablo Tobón Uribe, Colombia) at the 5h Saving Lives Sustainably Global Forum 2022 on 24 November 2022.
Resilient Circular Economy Medical Textile SolutionsUN SPHS
Dr. Tom Dawson (Founder, Revolution-ZERO and Visiting Research Fellow in Healthcare Circular Economics, University of Exeter) at the 5th Saving Lives Sustainably Global Forum 2022 on 24 November 2022.
Global Fund Emergency Response for BangladeshUN SPHS
Lahiru Perera (Project Manager, UNOPS) and Ekramul Haque (Deputy Program Manager, National Malaria Elimination & Aedes Transmitted Diseases Control Program, PM, BAN-MAL & Dengue; CDC, DGHS) at the 5th Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Vaccine supply chain: challenges and opportunitiesUN SPHS
Dr. Asel Sartbaeva
(Reader in Chemistry Department of Chemistry, University of Bath) at the 5th Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Reducing wasted medical equipment donated by iNGOsUN SPHS
Rodrigo Acosta, Zermeno Biomedical Specialist, International Committee of the Red Cross (ICRC), at the 5th Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Understanding and addressing the effects of the pandemic on health care waste...UN SPHS
Paeng Lopez, Plastics in Health Care Project Coordinator, Health Care Without Harm Asia, at the 5th Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Building sustainability into the NHS Supply ChainUN SPHS
By Alexandra Hammond, Head of Sustainable Procurement and Supply, NHS England at the 5th Saving Lives Sustainably Global Forum 2022 on 23 November 2022.
Sustainable Procurement Index for Health (SPIH) Virtual SessionUN SPHS
This virtual session provides you with an overview of the Sustainable Procurement Index for Health (SPIH). Details are provided on how the SPIH is structured, an overview of the key themes and questions, and the scoring system. Typical use cases for the SPIH are set out, and feedback from recent piloting and testing sessions is shared.
For more information please contact Ian Milimo at ian.milimo@undp.org and visit savinglivesustainably.org
Delivered by Eng. Nizar Al-Hariri, President, National Industrial Development Center, Saudi Arabia at the Global Forum 2020 Innovators from the Field session.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
2. How We Work.
We raise the money
The Global Fund Secretariat based in Geneva, Switzerland, raises and invests
more than US$4 billion a year to support programs.
2
Oversight in Action
Local Fund Agents in each country monitor the implementation of grants.
The Global Fund’s Office of the Inspector General conducts audits and investigations.
The Secretariat reports information to the Global Fund Board and the wider public.
Who We Are.
A 21st partnership organization to accelerate the end of HIV, tuberculosis and malaria as epidemics
2018-2020
period
Amount Countries
USD million % #
HIV/AIDS 5,098 50% 105
Malaria 3,227 32% 71
TB 1,842 18% 98
Where the Programs Are. 4%
Eastern Europe
and Central Asia
19%
Asia and
the Pacific
65%
Sub-Saharan
Africa
8%
North Africa
And the
Middle East
4%
Latin America
and the Caribbean
3. 3
Funding
Procurement
Services Agent
Recipient Country Manufacturer
Funding
Agency
PSA PR ManufacturerProducts
Other Procurement Agents,
Global Drug Facility (TB)
Funding
Agency
PSA PR ManufacturerProducts
Funding
Agency
PSA PR ManufacturerProducts
Funds
Orders
Long Term Agreements and Funds
Orders
Pooled Procurement
Mechanism (PPM)
Funds
Orders
National Procurement
Mechanisms
Approx. 1bn USD Health
Products are managed through
PPM, presenting 55% of the
GF funded health products
Global Fund utilizes a number of procurement channels to supply health
products to its grants
4. In December 2016,
GF formally
committed to
collectively advance
environmentally
and socially
responsible
procurement
through engagement
with suppliers of
health products.
GF is advancing responsible procurement aims in partnership
GF is a
member of
the UN
Informal
Interagency
Task Team on
Sustainable
Procurement
in the Health
Sector
(SPHS).
https://savinglivesustainably.org/who-we-are.html
5. GF has defined a tailored, holistic responsible procurement
approach across 4 elements
SOURCE: Adapted from corporate responsibility's framework by Crane et al, 2014
Principles for building
holistic standards
▪Build on existing
guidelines
▪Provide practical
guidance
▪Include phased
approach
▪Focus on procurement
▪Align with GF objectives
Dimen-
sions
Description
Ecology
▪Mitigate effect on environment along the
end-to-end supply chain
▪Use knowledge and skills to contribute
to a constant rise in eco-efficiency
Society
▪Promote fundamental human rights, e.g.,
–Advocate for decent labor conditions
–Promote children rights
▪Promote workers’ health and safety
Economy
▪Provide additional economic benefits to in-
country community
▪Empower community by sharing knowledge
▪Promote best business practices among
suppliers and other buyers
Business
practices
6. GF addresses each dimension of responsible procurement’s
framework through a case-by-case approach
SolutionsIssuesCase examples
Dimension
addressed
▪ GF mandated social and environmental assessment by a
3rd party for 7 LLIN production sites in 3 countries
▪ GF provided action plans for each site assessed to
implement environmental and labor regulations
▪ GF encouraged Principal Recipients to order bulk
packaging of LLINs for campaigns, reducing plastic
waste in 2018 to date by an estimated 930 tonnes
▪ LLIN manufacturing countries have weak
regulators’ focus on textile
▪ Plastics and insecticides used for LLINs
present high chemical risks for environment
▪ Historical reputational issues related to
corruption, environment and disposal
LLIN
Artemisinin
▪ GF mitigated price volatility and environmental risks by
visiting agricultural artemisinin producers and reviewing
Environmental, Health and Safety (EHS) practices:
– GF conducted agricultural artemisinin manufacturer
qualification through 3rd party
– GF incentivized best practices by manufacturers
through 3 year volume allocations
▪ Agricultural artemisinin prices are volatile due to:
– Overproduction capacity because of low
technical barrier to entry
– Lack of harmonized quality standards
▪ Agricultural artemisinin price volatility causes
supply interruptions to ACT suppliers
▪ Prior reliance on spot tenders contributed to
an important reliance on delivery by air
▪ Poor performing suppliers lobby when losing
volumes
▪ Outer/secondary paper cartons traditionally
included for multi-month ARV packs increase
transportation weight and waste
▪ GF implements performance-based allocations to
suppliers, with more than 80% of ARV volume shipped
by sea
▪ GF encouraged Principal Recipients to switch to
carton-less packaging of multi-month ARVs, reducing
freight volume, costs, paper and waste
ARV
EcologySociety Economy
Business
practices
7. Continue to gather and address inputs from
partner organizations
Continue to refine holistic responsible framework
based on best practices
Continue to build best business practices
Stepping stones going forward
Continue to incorporate Responsible Procurement into
Global Fund sourcing and supply chain practices
8. 8
► Investment of US$14 billion to save
16 million lives
► Avert 234 million infections/cases
and reduce the incidence rate
by 42%
► Reduce the death toll