PRINCIPLES OF GENERAL,
REGIONAL AND LOCAL
ANAESTHESIA
DR. MAITRI TALEKAR
ANAESTHESIA DEFINITION
• insensitivity to pain, especially as artificially
induced by the administration of gases or
the injection of drugs before surgical
operations
HISTORY OF ANESTHESIA
• General anesthesia was absent until the mid- 1800s.
• Ether used as anesthetic in 1842 by Dr. Crawford W.long
• Ether publicized as anesthetic in 1846 by Dr. William Morton.
• Ether is no longer used in modern practice, yet considered to be the first
ideal' anesthetic
• Chloroform used as anesthetic in 1853 by Dr. John Snow
• Endotracheal tube discovered in 1878
• Thiopental first used in 1934
General anesthesia - for surgical procedure to render the patient
unaware/unresponsive to the painful stimuli.
Drugs producing General Anesthesia - are called GENERAL
ANAESTHETICS
Regional and Local anesthesia - reversible inhibition of impulse
generation and propagation in nerves. Drugs producing local
anaesthesia - are called LOCAL ANAESTHETICS
GENERAL ANAESTHESIA
• General anaesthetics (GAs) are drugs which produce reversible
loss of all sensations and consciousness. It usually involves a
loss of memory and awareness with insensitivity to painful
stimuli, during a surgical procedure
Classic Stages of Anesthesia
Stage 1: Analgesia
decreased awareness of pain, amnesia ,without loss of consciousness
Stage 2:excitation
delirium & excitation, enhanced reflexes,retching, incontinence,
irregular respiration
Stage 3: Surgical Anaesthesia
Unconscious, no pain reflexes, regular respiration
Stage 4: Medullary Depression
Respiratory and CV depression requiring ventilation ad
pharmacological support
1. HYPNOSIS
2. ANALGESIA
3. MUSCLE RELAXATION
REGIONAL ANAESTHESIA
• A local anaesthetic is injected to block or
anaesthetise a nerve or nerve fibers
• Implies a major nerve block administered by
an anesthesiologist (such as spinal, epidural,
caudal, or major peripheral block)
POSITION FOR SPINAL / EPIDURAL
ANAESTHESIA
Mechanism of Action
• Principle site of action - Nerve Root
• LA bathes the nerve root in subarachnoid or epidural space
• Spinal Anaesthesia- direct injection of LA into CSF, with lesser
volume of drugs
• Epidural Anaesthesia- LA injected in epidural space at nerve
roots, with higher volume of drugs
• Local anesthetic solutions block sensory,
autonomic and motor impulses as the
anterior and posterior nerve roots pass
through the CSF. It is NOT the spinal cord!
• The site of action includes the spinal nerve
roots and the dorsal root ganglion.
TECHNIQUE OF SPINAL
ANAESTHESIA
• Spinal needle is inserted with the stylet through the introducer
• Needle should be inserted in the midline and directed cranially
at an angle of less than 50 degrees to the longitudinal axis of the
vertebral column
• Bevel of the spinal needle should be kept parallel to the
longitudinal axis of the spine
• Loss of resistances can be felt after puncturing ligamentum
flavum and the duramater
PERIPHERAL NERVE BLOCKS
• Surgery limited to one extremity (ideally one nerve
distribution)
• Moderate to severe postoperative pain anticipated
• Facilitate same-day discharge and avoid hospitalization for
pain management
• Improve vascular supply
• Early physical therapy and rehabilitations
LOCAL ANAESTHESIA
• Employed for minor procedures in which the
surgical site is infiltrated with a local anesthetic
• May inject drugs such as lidocaine or
bupivacaine
• Can be done on OPD basis or daycare surgery
MECHANISM OF ACTION
• Local anaesthetics reversibly block impulse
conduction along axons and other excitable
membranes that utilize sodium channels as the
primary means of action potential generation.
• This action can be used clinically to block pain
sensation.
INDICATIONS
• Incision and drainage of incised abscess.
• Removal of cysts, residual infection areas, neoplastic growths,
ranula and salivary calculi.
• Most dental procedures.
• Suturing of open wound.
THANK YOU

General/Local/Regional Anaesthesia types.pptx

  • 1.
    PRINCIPLES OF GENERAL, REGIONALAND LOCAL ANAESTHESIA DR. MAITRI TALEKAR
  • 2.
    ANAESTHESIA DEFINITION • insensitivityto pain, especially as artificially induced by the administration of gases or the injection of drugs before surgical operations
  • 4.
    HISTORY OF ANESTHESIA •General anesthesia was absent until the mid- 1800s. • Ether used as anesthetic in 1842 by Dr. Crawford W.long • Ether publicized as anesthetic in 1846 by Dr. William Morton. • Ether is no longer used in modern practice, yet considered to be the first ideal' anesthetic • Chloroform used as anesthetic in 1853 by Dr. John Snow • Endotracheal tube discovered in 1878 • Thiopental first used in 1934
  • 6.
    General anesthesia -for surgical procedure to render the patient unaware/unresponsive to the painful stimuli. Drugs producing General Anesthesia - are called GENERAL ANAESTHETICS Regional and Local anesthesia - reversible inhibition of impulse generation and propagation in nerves. Drugs producing local anaesthesia - are called LOCAL ANAESTHETICS
  • 9.
  • 10.
    • General anaesthetics(GAs) are drugs which produce reversible loss of all sensations and consciousness. It usually involves a loss of memory and awareness with insensitivity to painful stimuli, during a surgical procedure
  • 12.
    Classic Stages ofAnesthesia Stage 1: Analgesia decreased awareness of pain, amnesia ,without loss of consciousness Stage 2:excitation delirium & excitation, enhanced reflexes,retching, incontinence, irregular respiration Stage 3: Surgical Anaesthesia Unconscious, no pain reflexes, regular respiration Stage 4: Medullary Depression Respiratory and CV depression requiring ventilation ad pharmacological support
  • 14.
  • 16.
  • 18.
  • 23.
  • 25.
    • A localanaesthetic is injected to block or anaesthetise a nerve or nerve fibers • Implies a major nerve block administered by an anesthesiologist (such as spinal, epidural, caudal, or major peripheral block)
  • 27.
    POSITION FOR SPINAL/ EPIDURAL ANAESTHESIA
  • 28.
    Mechanism of Action •Principle site of action - Nerve Root • LA bathes the nerve root in subarachnoid or epidural space • Spinal Anaesthesia- direct injection of LA into CSF, with lesser volume of drugs • Epidural Anaesthesia- LA injected in epidural space at nerve roots, with higher volume of drugs
  • 29.
    • Local anestheticsolutions block sensory, autonomic and motor impulses as the anterior and posterior nerve roots pass through the CSF. It is NOT the spinal cord! • The site of action includes the spinal nerve roots and the dorsal root ganglion.
  • 30.
  • 31.
    • Spinal needleis inserted with the stylet through the introducer • Needle should be inserted in the midline and directed cranially at an angle of less than 50 degrees to the longitudinal axis of the vertebral column • Bevel of the spinal needle should be kept parallel to the longitudinal axis of the spine • Loss of resistances can be felt after puncturing ligamentum flavum and the duramater
  • 33.
    PERIPHERAL NERVE BLOCKS •Surgery limited to one extremity (ideally one nerve distribution) • Moderate to severe postoperative pain anticipated • Facilitate same-day discharge and avoid hospitalization for pain management • Improve vascular supply • Early physical therapy and rehabilitations
  • 36.
  • 37.
    • Employed forminor procedures in which the surgical site is infiltrated with a local anesthetic • May inject drugs such as lidocaine or bupivacaine • Can be done on OPD basis or daycare surgery
  • 38.
    MECHANISM OF ACTION •Local anaesthetics reversibly block impulse conduction along axons and other excitable membranes that utilize sodium channels as the primary means of action potential generation. • This action can be used clinically to block pain sensation.
  • 39.
    INDICATIONS • Incision anddrainage of incised abscess. • Removal of cysts, residual infection areas, neoplastic growths, ranula and salivary calculi. • Most dental procedures. • Suturing of open wound.
  • 43.