2. Pathophysiology
Secretion of saliva
Esophageal peristalsis
Esophageal clearance
Lower esophageal sphincter
Intra-abdominal esophagus
Angle of His
Pinchcock action
Gastric volume and emptying
3. Pathophysiology
GER causing GER
Respiratory factors
Medications and Hormones
Underlying Gastric acid
Pepsin, Trypsin and Bile salts
Intra-abdominal pressure
GER congenital problems
11. Indication for surgical treatment
Failure of medical Therapy
◦ Persistent pulmonary symptoms
◦ Life-threatening events
◦ Vomiting with failure to thrive
◦ Unremitting heartburn
◦ Inability to wean from medical therapy
Presence of an associated anatomic defect
Esophageal stricture
Post-EA repair stricture
Neurologically impaired children with GER
SPK 11
13. Associated Procedures & Complications
Pyloroplasty or Antroplasty
Gastrostomy
Complications
Bleeding from short gastric, spleen, aberrant left gastric
Lap: Perforation of esophagus, stomach 1% of cases
Pneumothorax
Conversion to open surgery
Dysphagia/also due to dysmotility
RECURRENT REFLUX-postoperative retching and gagging
Gas bloat and inability to vomit
Dumping Syndrome