Future trends in global healthcare will see rising costs become unsustainable, leading to reforms. Reimbursements are expected to decrease by 10% over the next decade as risk shifts from payers to providers. Payment will differ based on outcomes, satisfaction, and access. To prepare, providers must drive down costs, improve outcomes, and diversify revenue through clinical integration and managing episodes of care across larger systems. The creation of true healthcare systems is needed to efficiently standardize processes and align incentives to manage costs and risk.