Foam furniture and children's products that contain dangerous chemical flame retardants, from leading retailers including West Elm, Target, Babies R Us, and more.
Consumer perception the base for decision making. People make decisions instantly within 20 seconds about other person, yet when it comes to product they take more time. If the perception tone is set right by the companies consumer will not have any confusions. This presentation explores the ways and means of consumer perception and ends with the application of perception at large by organizations around the globe.
Consumer perception the base for decision making. People make decisions instantly within 20 seconds about other person, yet when it comes to product they take more time. If the perception tone is set right by the companies consumer will not have any confusions. This presentation explores the ways and means of consumer perception and ends with the application of perception at large by organizations around the globe.
TOPIC: “Chemical Exposures & Life-Long Reproductive Health Impacts”
We will review what we understand about reproductive biology and environmental contamination exposure. We’ll discuss the role of environmental chemicals in breast development and puberty, increased susceptibility to breast cancer and exposures during early life development of both male and female offspring and life-long impacts from chemical exposure. We’ll also discuss some of the potential health implications of energy development based on what we currently understand about exposures during early reproductive and developmental biology.
SPEAKER BIO: Suzanne Fenton, Ph.D., is Group Leader, NIH, Reproductive Endocrinology Group, Mammary Gland Development/Lactation Biology and a reproductive endocrinologist working at the National Toxicology Program Laboratory with the Division of the National Toxicology Program at National Institute of Environmental Health Sciences.
Moderator: Seth B. Shonkoff, Ph.D., M.P.H., Executive Director, PSE Healthy Energy & Environmental Researcher, UC Berkeley. Dr. Shonkoff assesses the health and climate dimensions of oil and gas development in the United States and abroad.
TOPIC: “The Way Forward”
This panel will focus on linking the reproductive health research to policy, how we need to advance scientific inquiry, professional training, public education and health policies that reduce the impacts of environmental contaminants on reproductive and developmental health. We’ll close the last session with goals for the future and discuss the importance of creating policies that support a truly clean energy future.
SPEAKER BIO: Rachel Morello-Frosch, PhD, MPH, Professor, Department of Environmental Science, Policy, & Management, University of California – Berkeley. Dr. Morello-Frosch’s research examines race and class determinants of environmental health among diverse communities in the US with a focus on social inequality, psychosocial stress and how these factors interact with environmental chemical exposures to produce environmental health inequalities.
SPEAKER BIO: Kathryn Phillips, Director, Sierra Club, California. As Director, Kathryn leads legislative and regulatory advocacy and overall administration of Sierra Club, California. Kathryn covers or oversees coverage of nearly every environmental issue that crosses the transom at the State Capitol and in key agencies. This includes energy, transportation, wildlife, forestry, water, climate disruption, and air quality.
Moderator: Caroline Cox, Research Director, CEH. Caroline leads CEH’s research on toxic exposures, identifying, analyzing and substantiating the scientific bases for CEH’s work to eliminate threats to children and others expose to dangerous chemicals in consumer products.
TOPIC: “Hormonal Activity in Water Samples: Implications for Reproductive Health”
We’ll discuss hormonal activity in water near hydraulic fracturing sites, the potential for endocrine disruption, and the resulting health impacts. We’ll look at the influence of chemicals in the fracking process on the human endocrine system, estrogen action, prenatal origins of adult disease and epigenetics.
SPEAKER BIO: Susan Nagel, Ph.D., Associate Professor, Obstetrics, Gynecology and Women’s Health, University of Missouri School of Medicine. Dr. Nagel works in the Reproductive and Perinatal Research clinic focusing on developmental origins of adult disease, fetal programming and endocrine disruption.
TOPIC: “Adverse Birth Outcomes and Natural Gas Development”
We’ll discuss how potential environmental impacts from unconventional natural gas development in Marcellus Shale may influence reproductive health and pregnancy outcomes.
SPEAKER BIO: Lisa McKenzie, M.P.H., Ph.D., Research Associate, Colorado School of Public Health, Environmental & Occupational Health. Dr. McKenzie has a background in epidemiology and environmental chemistry. Her research interests include exposure assessment, air pollution and natural gas development.
Moderator: Sheila Bushkin, M.D., M.P.H., Institute for Health & the Environment, University at Albany. Dr. Buskin is a member of the Medical Society of the State of New York (MSSNY) since 1998. Her specific areas of interest involve chronic disease, aging, environmental health, and continuing medical education (CME).
TOPIC: “Broad Impacts of Fossil Fuel Emissions on Children’s Health and Development”
We will review what we currently understand about exposures during prenatal and early postnatal development and will discuss some of the potential health risks from fossil fuels.
SPEAKER BIO: Frederica Perera, Dr. P.H., Ph.D., Professor, Columbia University, Director, Columbia Center for Children’s Environmental Health. Dr. Perera is internationally recognized for pioneering the field of molecular epidemiology, utilizing biomarkers to understand links between environmental exposures and disease.
TOPIC: “Chemical Exposures & Life-Long Reproductive Health Impacts”
We will review what we understand about reproductive biology and environmental contamination exposure. We’ll discuss the role of environmental chemicals in breast development and puberty, increased susceptibility to breast cancer and exposures during early life development of both male and female offspring and life-long impacts from chemical exposure. We’ll also discuss some of the potential health implications of energy development based on what we currently understand about exposures during early reproductive and developmental biology.
SPEAKER BIO: Suzanne Fenton, Ph.D., is Group Leader, NIH, Reproductive Endocrinology Group, Mammary Gland Development/Lactation Biology and a reproductive endocrinologist working at the National Toxicology Program Laboratory with the Division of the National Toxicology Program at National Institute of Environmental Health Sciences.
Who this is for: Health professionals.
Description: Dr. Sheila Bushkin-Bedient will be speaking on the prenatal origins of disease and why we should be focusing on studying possible connections between unconventional natural gas extraction and diabetes, obesity, and cancer.
About the Speaker: Sheila Bushkin is a member of the Institute of Health and the Environment at the State University at Albany, and Concerned Health Professionals of New York. She has been a member of the Medical Society of the State of New York for 15 years. Her specific areas of interest involve environmental health issues, chronic diseases, health concerns of older adults, and CME for physicians.
Who this is for: Mothers and families
Description: Dr. David O. Carpenter will focus on environmental exposures that are known to result in reduced cognitive function in children, usually associated with shortened attention span, increased antisocial behavior and poorer performance in school.
About the Speaker: Carpenter is a public health physician whose current position is Director of the Institute for Health and the Environment at the University at Albany, as well as Professor of Environmental Health Sciences within the School of Public Health at the University at Albany. After receiving his MD degree from Harvard Medical School he chose a career of research and public health.
Who this is for: Mothers and families
Description: Nurse-Midwife Katie Huffling will be speaking about the susceptibility of women and fetuses during pregnancy in connection to unconventional natural gas drilling.
About the Speaker: Katie Huffling is a Certified Nurse-Midwife and is the Director of Programs for the Alliance of Nurses for Healthy Environments where she directors projects related to environmental health nursing practice, research, education, and policy and advocacy. She is also part of a national and international network of nurses that work to integrate environmental health into nursing education and provide guidance and resources to pregnant women, parents, and others about health risks to children and their families.
Who this is for: Mothers, families, the scientific community, and healthcare professionals.
Description: Carol Kwiatkowski talks about the public health implications of natural gas development, with an emphasis on air pollution and the risks they might hold for vulnerable populations, including children and pregnant women.
About The Speaker: Carol Kwiatkowski, Executive Director of TEDX, The Endocrine Disruption Exchange, and an Assistant Professor Adjunct at the University of Colorado Boulder. During her time at TEDX, she has created the Critical Windows of Development website, which presents a timeline of how the human body develops in the womb, with animal research showing when low-dose exposure to endocrine disrupting chemicals (EDCs) during development results in altered health outcomes.
The Center for Environmental Health tested these Forever 21 purses for the toxic metal lead and found high levels of lead in all of them. Twitter: @CEHPurseWatch
What's inside all those electronics and tech products you buy? Often, they're filled with toxic chemicals and rare earth minerals. This presentation addresses the history, and global demand for rare earth minerals, and the public and environmental health issues they cause.
The electronics industry is one of the fastest growing sectors of the global economic environment, but it is also one of the least researched businesses in regards to labor practices and worker conditions. The ubiquity of uninterrupted purchasing, using, and discarding of digital technology has inevitably increased demand for electronics manufacturing, which in turn fuels the need for cheaper, faster, and more efficient labor output. Consequently, many of these industries circumvent and violate national labor laws, mainly by outsourcing to developing countries, to maximize and maintain a high rate of production and distribution. In addition, many of these factories are incredibly “dirty” facilities, where workers are often unknowingly exposed to toxic chemicals that are used to make the electronic parts. The following presentation attempts to elucidate many secrets of the international electronics sector, focusing on the violation of human rights and the potential risk posed to human health and safety due to unethical labor practices.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TOPIC: “Chemical Exposures & Life-Long Reproductive Health Impacts”
We will review what we understand about reproductive biology and environmental contamination exposure. We’ll discuss the role of environmental chemicals in breast development and puberty, increased susceptibility to breast cancer and exposures during early life development of both male and female offspring and life-long impacts from chemical exposure. We’ll also discuss some of the potential health implications of energy development based on what we currently understand about exposures during early reproductive and developmental biology.
SPEAKER BIO: Suzanne Fenton, Ph.D., is Group Leader, NIH, Reproductive Endocrinology Group, Mammary Gland Development/Lactation Biology and a reproductive endocrinologist working at the National Toxicology Program Laboratory with the Division of the National Toxicology Program at National Institute of Environmental Health Sciences.
Moderator: Seth B. Shonkoff, Ph.D., M.P.H., Executive Director, PSE Healthy Energy & Environmental Researcher, UC Berkeley. Dr. Shonkoff assesses the health and climate dimensions of oil and gas development in the United States and abroad.
TOPIC: “The Way Forward”
This panel will focus on linking the reproductive health research to policy, how we need to advance scientific inquiry, professional training, public education and health policies that reduce the impacts of environmental contaminants on reproductive and developmental health. We’ll close the last session with goals for the future and discuss the importance of creating policies that support a truly clean energy future.
SPEAKER BIO: Rachel Morello-Frosch, PhD, MPH, Professor, Department of Environmental Science, Policy, & Management, University of California – Berkeley. Dr. Morello-Frosch’s research examines race and class determinants of environmental health among diverse communities in the US with a focus on social inequality, psychosocial stress and how these factors interact with environmental chemical exposures to produce environmental health inequalities.
SPEAKER BIO: Kathryn Phillips, Director, Sierra Club, California. As Director, Kathryn leads legislative and regulatory advocacy and overall administration of Sierra Club, California. Kathryn covers or oversees coverage of nearly every environmental issue that crosses the transom at the State Capitol and in key agencies. This includes energy, transportation, wildlife, forestry, water, climate disruption, and air quality.
Moderator: Caroline Cox, Research Director, CEH. Caroline leads CEH’s research on toxic exposures, identifying, analyzing and substantiating the scientific bases for CEH’s work to eliminate threats to children and others expose to dangerous chemicals in consumer products.
TOPIC: “Hormonal Activity in Water Samples: Implications for Reproductive Health”
We’ll discuss hormonal activity in water near hydraulic fracturing sites, the potential for endocrine disruption, and the resulting health impacts. We’ll look at the influence of chemicals in the fracking process on the human endocrine system, estrogen action, prenatal origins of adult disease and epigenetics.
SPEAKER BIO: Susan Nagel, Ph.D., Associate Professor, Obstetrics, Gynecology and Women’s Health, University of Missouri School of Medicine. Dr. Nagel works in the Reproductive and Perinatal Research clinic focusing on developmental origins of adult disease, fetal programming and endocrine disruption.
TOPIC: “Adverse Birth Outcomes and Natural Gas Development”
We’ll discuss how potential environmental impacts from unconventional natural gas development in Marcellus Shale may influence reproductive health and pregnancy outcomes.
SPEAKER BIO: Lisa McKenzie, M.P.H., Ph.D., Research Associate, Colorado School of Public Health, Environmental & Occupational Health. Dr. McKenzie has a background in epidemiology and environmental chemistry. Her research interests include exposure assessment, air pollution and natural gas development.
Moderator: Sheila Bushkin, M.D., M.P.H., Institute for Health & the Environment, University at Albany. Dr. Buskin is a member of the Medical Society of the State of New York (MSSNY) since 1998. Her specific areas of interest involve chronic disease, aging, environmental health, and continuing medical education (CME).
TOPIC: “Broad Impacts of Fossil Fuel Emissions on Children’s Health and Development”
We will review what we currently understand about exposures during prenatal and early postnatal development and will discuss some of the potential health risks from fossil fuels.
SPEAKER BIO: Frederica Perera, Dr. P.H., Ph.D., Professor, Columbia University, Director, Columbia Center for Children’s Environmental Health. Dr. Perera is internationally recognized for pioneering the field of molecular epidemiology, utilizing biomarkers to understand links between environmental exposures and disease.
TOPIC: “Chemical Exposures & Life-Long Reproductive Health Impacts”
We will review what we understand about reproductive biology and environmental contamination exposure. We’ll discuss the role of environmental chemicals in breast development and puberty, increased susceptibility to breast cancer and exposures during early life development of both male and female offspring and life-long impacts from chemical exposure. We’ll also discuss some of the potential health implications of energy development based on what we currently understand about exposures during early reproductive and developmental biology.
SPEAKER BIO: Suzanne Fenton, Ph.D., is Group Leader, NIH, Reproductive Endocrinology Group, Mammary Gland Development/Lactation Biology and a reproductive endocrinologist working at the National Toxicology Program Laboratory with the Division of the National Toxicology Program at National Institute of Environmental Health Sciences.
Who this is for: Health professionals.
Description: Dr. Sheila Bushkin-Bedient will be speaking on the prenatal origins of disease and why we should be focusing on studying possible connections between unconventional natural gas extraction and diabetes, obesity, and cancer.
About the Speaker: Sheila Bushkin is a member of the Institute of Health and the Environment at the State University at Albany, and Concerned Health Professionals of New York. She has been a member of the Medical Society of the State of New York for 15 years. Her specific areas of interest involve environmental health issues, chronic diseases, health concerns of older adults, and CME for physicians.
Who this is for: Mothers and families
Description: Dr. David O. Carpenter will focus on environmental exposures that are known to result in reduced cognitive function in children, usually associated with shortened attention span, increased antisocial behavior and poorer performance in school.
About the Speaker: Carpenter is a public health physician whose current position is Director of the Institute for Health and the Environment at the University at Albany, as well as Professor of Environmental Health Sciences within the School of Public Health at the University at Albany. After receiving his MD degree from Harvard Medical School he chose a career of research and public health.
Who this is for: Mothers and families
Description: Nurse-Midwife Katie Huffling will be speaking about the susceptibility of women and fetuses during pregnancy in connection to unconventional natural gas drilling.
About the Speaker: Katie Huffling is a Certified Nurse-Midwife and is the Director of Programs for the Alliance of Nurses for Healthy Environments where she directors projects related to environmental health nursing practice, research, education, and policy and advocacy. She is also part of a national and international network of nurses that work to integrate environmental health into nursing education and provide guidance and resources to pregnant women, parents, and others about health risks to children and their families.
Who this is for: Mothers, families, the scientific community, and healthcare professionals.
Description: Carol Kwiatkowski talks about the public health implications of natural gas development, with an emphasis on air pollution and the risks they might hold for vulnerable populations, including children and pregnant women.
About The Speaker: Carol Kwiatkowski, Executive Director of TEDX, The Endocrine Disruption Exchange, and an Assistant Professor Adjunct at the University of Colorado Boulder. During her time at TEDX, she has created the Critical Windows of Development website, which presents a timeline of how the human body develops in the womb, with animal research showing when low-dose exposure to endocrine disrupting chemicals (EDCs) during development results in altered health outcomes.
The Center for Environmental Health tested these Forever 21 purses for the toxic metal lead and found high levels of lead in all of them. Twitter: @CEHPurseWatch
What's inside all those electronics and tech products you buy? Often, they're filled with toxic chemicals and rare earth minerals. This presentation addresses the history, and global demand for rare earth minerals, and the public and environmental health issues they cause.
The electronics industry is one of the fastest growing sectors of the global economic environment, but it is also one of the least researched businesses in regards to labor practices and worker conditions. The ubiquity of uninterrupted purchasing, using, and discarding of digital technology has inevitably increased demand for electronics manufacturing, which in turn fuels the need for cheaper, faster, and more efficient labor output. Consequently, many of these industries circumvent and violate national labor laws, mainly by outsourcing to developing countries, to maximize and maintain a high rate of production and distribution. In addition, many of these factories are incredibly “dirty” facilities, where workers are often unknowingly exposed to toxic chemicals that are used to make the electronic parts. The following presentation attempts to elucidate many secrets of the international electronics sector, focusing on the violation of human rights and the potential risk posed to human health and safety due to unethical labor practices.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html