Friedreich's ataxia is an autosomal recessive genetic disorder that affects the nervous system and was first described in 1863, causing vision and hearing impairment, a weak heart, scoliosis, slurred speech, lack of motor coordination, and a short life span of 25-35 years. There is no cure for Friedreich's ataxia and treatment focuses on prolonging life slightly through exercise, physical therapy, and in some countries, the drug idebenone.

1. Friedreich's Ataxia
Travis Trusty- Pd. 4

2. Molecular Basis
Friedreich ataxia is an autosomal recessive
disorder. The disease was first described in
1863 by Nicholaus Friedreich. Friedreich
reported a “degeneration" of the
lower spinal column.

3. Physiological Effects
Vision and Hearing Impairment
Weak Heart
Scoliosis
Slurred Speech
No Motor Coordination
Short Life Span (25-35 years)

4. Treatment
Idebenone- illegal in the U.S.
NO cure- only prolong life slightly through
exercise and physical therapy

5. Consequences
Low life span can cripple a population.
Inability to work leaves many affected with
a poor standard of living.