This document discusses the EU Commission's request for EFSA to provide a scientific opinion and guidance on risk assessment of plant protection products (pesticides) on bees. It outlines the composition of the working group, terms of reference, and proposed chapters to cover introduction, protection goals, exposure assessment, chronic toxicity from low doses, test methods, cumulative/synergistic effects, and risk assessment methodology for honeybees, bumblebees and solitary bees. It provides details on the key sections including identifying the most exposed bee categories and life stages, major exposure routes, and proposing a new method to assess cumulative toxicity from long-term low exposures.
Franz Streissl - The revision of the GD on terrestrial ecotoxicologycropprotection
The document discusses the revision of the EFSA Guidance Document on terrestrial ecotoxicology. It provides background on EFSA taking over responsibility from the European Commission to revise existing guidance documents. It outlines the topics identified through a public consultation and Member State survey to be priority areas for updating the terrestrial guidance documents, including non-target organism risk assessment, effects of multiple exposures, and linking exposure to effects. The mandate for revision includes developing guidance on risk assessment for non-target arthropods, in-soil organisms, non-target plants, and amphibians/reptiles. Overarching issues for harmonization between guidance documents are also identified.
Stephanie Bopp - GD on aquatic ecotoxicologycropprotection
This document outlines the background and plans for revising the Guidance Document on Aquatic Ecotoxicology. It discusses the need to update the current guidance to align with new regulations and data requirements. The revision will take a modular approach, beginning with practical guidance on topics where "building blocks" already exist. The first module will focus on a tiered risk assessment for aquatic organisms in edge-of-field surface waters. Further modules will address topics like combined exposure/effect modelling, sediment organisms, and multiple stress assessment. The working group is currently drafting the first module and plans to seek public comment on the draft guidance in October 2012.
Sarra Gaspard - Sargassum Valorization by purolysis - application for food sa...Région Guadeloupe
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
1) PABRA develops, evaluates, and disseminates integrated crop management technologies to improve common bean productivity across sub-Saharan Africa. These technologies include improved varieties, disease and pest management, and integrated soil fertility.
2) Several promising technologies were tested on-station and on-farm in different countries, including quality seeds, staking techniques, botanical pesticides, fertilizers, and more.
3) Technologies are delivered to farmers through partnerships between research, extension, and other organizations, and by engaging policymakers to implement supportive agricultural policies. This has increased farmers' access to improved seeds and integrated management practices.
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
Pr. NEVIERE Remi - Human health consequences of long term exposure to gaseou...Région Guadeloupe
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasse
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
Pesticide use and toxicity A Presentation by Mr Allah Dad Khan Consultant NRM...Mr.Allah Dad Khan
The document discusses pesticide use and toxicity trends as well as integrated pest management (IPM) strategies. It notes that while conventional pesticide sales and use of certain pesticides have declined in recent years, pesticide contamination of water and fish remains widespread. IPM is presented as a systems-based approach that can help reduce environmental, health, and economic risks by preventing, avoiding, monitoring, and suppressing pests through cultural, biological, and chemical tactics. Basic IPM practices include scouting, monitoring conditions, and timing pest management actions, while advanced practices incorporate pest-resistant varieties, crop rotation, reduced-risk pesticides, and beneficial insects.
Franz Streissl - The revision of the GD on terrestrial ecotoxicologycropprotection
The document discusses the revision of the EFSA Guidance Document on terrestrial ecotoxicology. It provides background on EFSA taking over responsibility from the European Commission to revise existing guidance documents. It outlines the topics identified through a public consultation and Member State survey to be priority areas for updating the terrestrial guidance documents, including non-target organism risk assessment, effects of multiple exposures, and linking exposure to effects. The mandate for revision includes developing guidance on risk assessment for non-target arthropods, in-soil organisms, non-target plants, and amphibians/reptiles. Overarching issues for harmonization between guidance documents are also identified.
Stephanie Bopp - GD on aquatic ecotoxicologycropprotection
This document outlines the background and plans for revising the Guidance Document on Aquatic Ecotoxicology. It discusses the need to update the current guidance to align with new regulations and data requirements. The revision will take a modular approach, beginning with practical guidance on topics where "building blocks" already exist. The first module will focus on a tiered risk assessment for aquatic organisms in edge-of-field surface waters. Further modules will address topics like combined exposure/effect modelling, sediment organisms, and multiple stress assessment. The working group is currently drafting the first module and plans to seek public comment on the draft guidance in October 2012.
Sarra Gaspard - Sargassum Valorization by purolysis - application for food sa...Région Guadeloupe
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
1) PABRA develops, evaluates, and disseminates integrated crop management technologies to improve common bean productivity across sub-Saharan Africa. These technologies include improved varieties, disease and pest management, and integrated soil fertility.
2) Several promising technologies were tested on-station and on-farm in different countries, including quality seeds, staking techniques, botanical pesticides, fertilizers, and more.
3) Technologies are delivered to farmers through partnerships between research, extension, and other organizations, and by engaging policymakers to implement supportive agricultural policies. This has increased farmers' access to improved seeds and integrated management practices.
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
Pr. NEVIERE Remi - Human health consequences of long term exposure to gaseou...Région Guadeloupe
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasse
International conférence on sargassum
Wednesday, October 23 rd
Results of the international Call “Sargassum”
----
Conférence Internationale sur les Sargasses
Mercredi 23 Octobre
Résultats de l’AAP international sargasses
Pesticide use and toxicity A Presentation by Mr Allah Dad Khan Consultant NRM...Mr.Allah Dad Khan
The document discusses pesticide use and toxicity trends as well as integrated pest management (IPM) strategies. It notes that while conventional pesticide sales and use of certain pesticides have declined in recent years, pesticide contamination of water and fish remains widespread. IPM is presented as a systems-based approach that can help reduce environmental, health, and economic risks by preventing, avoiding, monitoring, and suppressing pests through cultural, biological, and chemical tactics. Basic IPM practices include scouting, monitoring conditions, and timing pest management actions, while advanced practices incorporate pest-resistant varieties, crop rotation, reduced-risk pesticides, and beneficial insects.
This document discusses expanding herbicide options for weed management in natural areas. It outlines the IR4 Project process for developing data to support new EPA approvals of herbicide uses. Several potential herbicide prospects are identified, including mesotrione, which could provide a new mode of action for resistance management of winter annual grasses and broadleaves. However, obtaining approvals for natural areas uses faces challenges like demonstrating effectiveness for diverse conditions and review of potential nontarget impacts. Industry may be hesitant due to the small market size and liability risks compared to agricultural uses.
Bioprospecting involves systematically searching for useful products from biological resources like plants, microorganisms, and animals that can be developed and commercialized for societal benefit. It generally consists of four phases: sample collection, isolation and characterization of compounds, screening for potential uses, and product development and commercialization. Microbes, extremophiles, fungi, algae, and other organisms provide sources for bioprospecting and have led to discoveries like antibiotics, enzymes, bioplastics, and more. While bioprospecting has benefits, issues around benefit-sharing with indigenous groups and biopiracy must be addressed.
This document summarizes an international collaboration to research the medicinal potential of Caribbean sargassum seaweed. The collaboration involves associations in Martinique studying natural resources and epidemiology/biodiversity, as well as an institute in Nice, France. They aim to detect pharmacological potentials of sargassum extracts against diseases prevalent in the Caribbean by testing extracts on disease cell models and identifying active compounds. Work packages include collecting sargassum, optimizing extracts, screening extracts for therapeutic activity against cancers, infections and neurodegenerative diseases, studying mechanisms of action, and disseminating results. The collaboration expects to contribute innovative training, leverage international expertise, and relate biological activities to molecular identifications.
The document discusses the status of the National Pollutant Discharge Elimination System (NPDES) permit program as it relates to pesticide applications. It notes that a court ruling determined pesticide applications require an NPDES permit as they are a point source of pollution. EPA was granted stays to develop the permit program but faced delays. Georgia's environmental agency intends to follow EPA's pesticide general permit. The document provides details on permit requirements including developing a Pesticide Discharge Management Plan, submitting a Notice of Intent, record keeping, reporting, and other compliance elements.
The document provides information on chemical control of forest pests. It discusses definitions of chemical control and insecticides. It also covers the history of insecticide development, different classifications of insecticides based on origin, mode of entry, mode of action and toxicity. Properties of an ideal insecticide are also outlined, including being non-toxic to non-target species and having a wide range of compatibility. The classifications include inorganic, organic and synthetic insecticides as well as contact, stomach and systemic types.
PhD First year presentation at Macquarie UniversityIndrani Sarker
This document summarizes a research project on the impact of plastic leachate on marine picocyanobacteria. The project aims to (1) determine the physiological effects of different plastic leachates on Prochlorococcus and Synechococcus strains over short and long term exposure, (2) examine the transcriptomic basis for variability in responses to leachate stress, and (3) develop methods to identify individual toxicants responsible for plastic leachate toxicity. The research will involve exposing cyanobacteria to plastic leachates, analyzing changes in growth, gene expression through RNA sequencing, and applying toxicity identification evaluation techniques to characterize leachate composition.
This document outlines a framework for assessing the externalities of nitrogen fertilizers. It discusses the benefits of nitrogen fertilizers, including higher crop yields, as well as downsides such as energy intensive manufacturing processes that are polluting. It then presents a methodology for quantifying emitted pollutants from nitrogen fertilizer production and application, such as carbon dioxide, nitrous oxide, ammonia, and particulate matter. The document monetizes these emissions using damage costs per ton reported by various studies. As an example, the environmental costs of nitrogen fertilizer use in UK agriculture is estimated to be 216 euros per hectare, or 36% of the sector's gross value added. Finally, the document discusses a two-track policy approach involving
This document summarizes a proposed research project called CESAR (Coastal Environment under Sargassum crisis). The project aims to provide knowledge and tools to help manage Sargassum influxes in the Caribbean region, particularly the French West Indies. It will involve monitoring and forecasting Sargassum distributions using satellite data and ocean models. The project is led by a consortium of research organizations and will have two work packages. The first will focus on satellite monitoring and developing forecasting capabilities, while the second will examine governance and policy related to Sargassum management. Expected results include improved detection algorithms, transport modeling of Sargassum, and policy recommendations to help decision makers address Sargassum
This document summarizes a proposed research project on integrating bioassays into assessments of aquatic ecosystem quality under the European Water Framework Directive. The project aims to gauge how combining standard ecological quality assessments with ecologically relevant bioassays can improve the ability to assess and manage European water bodies. It will focus on developing in situ bioassays using species found in the Mondego Estuary, and integrating the results of the bioassays with other monitoring data. Over summer and winter, a battery of in situ bioassays will be performed at sampling stations in the estuary using selected species. Water, sediment, and invertebrate data will also be collected. Multivariate tools will be used to integrate the bioassay results with
1. The document outlines steps for students to conduct field studies to understand ecosystems, including identifying abiotic and biotic components, investigating interactions between components, and studying processes like colonization and succession.
2. Students are instructed to identify trophic levels, study competition between species, and conduct experiments on topics like the effects of abiotic factors on population distribution.
3. Additional topics covered include the need for classification of organisms, the five kingdoms of life, and the importance of biodiversity. Students are to demonstrate understanding of these concepts.
Nanotoxicology is the study of the toxicity of nanomaterials. As the size of particles decreases, their surface area increases, allowing more of their atoms and molecules to interact with the environment and potentially cause toxic effects. Nanomaterials can enter the body through various routes and distribute to organs, where they may cause toxicity through effects like inflammation, DNA damage, and tissue damage. They may also pollute the environment through deposition in water, soil, and plants. Occupational, consumer, and environmental exposures are increasing as nanotechnology applications expand. The toxicity depends on factors like surface area, chemical composition, and ability to interact with and inhibit enzymes.
This document discusses GMOs and related issues including risks and regulations. It outlines both the advantages and disadvantages of GMOs, such as increased crop yields but also potential risks to human health and the environment. The document examines myths around GMOs and discusses controversies including safety, intellectual property access, ethics, and labeling. It also reviews principles of risk analysis for GMOs and biosafety guidelines and regulations in India and internationally. In conclusion, the author notes the field of biosafety is controversial but proponents see benefits while critics see risks that may be unacceptable without sufficient scientific certainty and precautions.
Center of Excellence on Climate Change Research for Plant Protection (CoE-CCRPP)ICRISAT
This document outlines the goals and objectives of the Center of Excellence on Climate Change Research for Plant Protection (CoE-CCRPP). The CoE-CCRPP aims to establish facilities and provide opportunities for research on the impact of climate change on diseases and insect pests affecting legumes. Its objectives are to analyze weather data and its relationship to pests and pathogens, evaluate crop resistance under climate change, and predict potential changes in the distribution and abundance of pests and diseases. The CoE-CCRPP will also work to standardize techniques to study interactions between crops, pests, pathogens and the environment in relation to climate variables and build capacity for climate change research.
1) Silver nanoparticles are intentionally produced engineered nanomaterials that are being used in many consumer products due to their antibacterial properties. However, there is concern about their potential impacts on human health and the environment.
2) The project aimed to develop methods to detect silver nanoparticles in water, determine their toxicological effects in aquatic environments, and develop risk assessment protocols.
3) Key findings included that activated charcoal can effectively capture silver nanoparticles from water, effects were observed on aquatic organisms in toxicity tests, and current models estimate low environmental concentrations pose low risks to human health through drinking water. However, more studies are needed to monitor silver nanoparticles in Ireland's environment and risks.
Neonicotinoids: The Science and Regulatory ComplexityCovance
The document provides an overview of neonicotinoids (neonics), a class of insecticides similar to nicotine. It discusses the history and rationale for their use in agriculture, their chemical properties and modes of action. It also reviews concerns about their effects on bees and other pollinators. The regulatory review process of neonics in the European Union is examined, including risk assessments by the European Food Safety Authority that led to restrictions on the use of imidacloprid, clothianidin and thiamethoxam due to risks to bees. The limitations and timeline of the regulatory process in the EU are outlined.
Antifouling wrap: a sustainable solutions for biofouling preventionlenses
The document discusses the development of Antifouling Wrap, a sustainable solution for biofouling prevention on ship hulls using nanotechnology and wrap strategies. It aims to develop environmentally friendly marine coatings that do not use biocides. The research tested various film materials on ship hull samples and found that a flocked PVC surface had fouling release and self-cleaning properties, reducing hull maintenance time by up to 80% compared to traditional paints. Future work will explore optimizing the film surface design and integrating antibacterial compounds to further improve the antifouling performance of the wrap solution.
Program for the rehabilitation and restoration presentation2 Maricar Onggon
This document outlines a program to rehabilitate mined out areas in the Philippines using phytotechnologies. It describes 3 projects, each led by a different project leader and focusing on: 1) conserving native metallophytes and testing phytostabilization in Palawan, Surigao, and Zambales, 2) identifying metal bioindicator species in 6 sites and creating a database, and 3) identifying copper and arsenic hyperaccumulators for potential post-mining metal recovery. The overall objectives are to study indigenous metallophyte species for phytotechnologies and develop protocols for their propagation and use in phytoremediation and post-mining activities.
This document summarizes the key points from a presentation on the safety and toxicity related to nanopharmaceuticals. It discusses nanotoxicology and some of the reasons nanoparticles can be toxic, such as their large surface area to volume ratio. It covers toxicological factors, routes of exposure including inhalation, skin contact and ingestion. Diseases associated with nanoparticles are mentioned. The document provides an overview of ensuring safety in nanopharmaceuticals through measures like material safety data sheets, personal protective equipment, safety engineering controls and proper disposal procedures. It concludes more research is still needed to understand nanoparticle toxicity and ensure safer materials can be developed.
The presentation shows how urban gardens that contain flowering perennial plants provide food, habitat, and sanctuary for native bees and other beneficial insects.
Letus Capital SA is a corporate finance advisory firm that provides services such as mergers and acquisitions advisory, capital raising, IPOs, and valuations. Some of their notable clients and projects include advising Integer.pl SA on their IPO and acquisition deals, advising PKN Orlen on a $500 million investment project, and advising Graal SA on their IPO and acquisition deals. Letus Capital has over 100 completed projects and experience advising companies across various industries. They transformed into a public company in 2008 when they debuted on NewConnect.
This document discusses expanding herbicide options for weed management in natural areas. It outlines the IR4 Project process for developing data to support new EPA approvals of herbicide uses. Several potential herbicide prospects are identified, including mesotrione, which could provide a new mode of action for resistance management of winter annual grasses and broadleaves. However, obtaining approvals for natural areas uses faces challenges like demonstrating effectiveness for diverse conditions and review of potential nontarget impacts. Industry may be hesitant due to the small market size and liability risks compared to agricultural uses.
Bioprospecting involves systematically searching for useful products from biological resources like plants, microorganisms, and animals that can be developed and commercialized for societal benefit. It generally consists of four phases: sample collection, isolation and characterization of compounds, screening for potential uses, and product development and commercialization. Microbes, extremophiles, fungi, algae, and other organisms provide sources for bioprospecting and have led to discoveries like antibiotics, enzymes, bioplastics, and more. While bioprospecting has benefits, issues around benefit-sharing with indigenous groups and biopiracy must be addressed.
This document summarizes an international collaboration to research the medicinal potential of Caribbean sargassum seaweed. The collaboration involves associations in Martinique studying natural resources and epidemiology/biodiversity, as well as an institute in Nice, France. They aim to detect pharmacological potentials of sargassum extracts against diseases prevalent in the Caribbean by testing extracts on disease cell models and identifying active compounds. Work packages include collecting sargassum, optimizing extracts, screening extracts for therapeutic activity against cancers, infections and neurodegenerative diseases, studying mechanisms of action, and disseminating results. The collaboration expects to contribute innovative training, leverage international expertise, and relate biological activities to molecular identifications.
The document discusses the status of the National Pollutant Discharge Elimination System (NPDES) permit program as it relates to pesticide applications. It notes that a court ruling determined pesticide applications require an NPDES permit as they are a point source of pollution. EPA was granted stays to develop the permit program but faced delays. Georgia's environmental agency intends to follow EPA's pesticide general permit. The document provides details on permit requirements including developing a Pesticide Discharge Management Plan, submitting a Notice of Intent, record keeping, reporting, and other compliance elements.
The document provides information on chemical control of forest pests. It discusses definitions of chemical control and insecticides. It also covers the history of insecticide development, different classifications of insecticides based on origin, mode of entry, mode of action and toxicity. Properties of an ideal insecticide are also outlined, including being non-toxic to non-target species and having a wide range of compatibility. The classifications include inorganic, organic and synthetic insecticides as well as contact, stomach and systemic types.
PhD First year presentation at Macquarie UniversityIndrani Sarker
This document summarizes a research project on the impact of plastic leachate on marine picocyanobacteria. The project aims to (1) determine the physiological effects of different plastic leachates on Prochlorococcus and Synechococcus strains over short and long term exposure, (2) examine the transcriptomic basis for variability in responses to leachate stress, and (3) develop methods to identify individual toxicants responsible for plastic leachate toxicity. The research will involve exposing cyanobacteria to plastic leachates, analyzing changes in growth, gene expression through RNA sequencing, and applying toxicity identification evaluation techniques to characterize leachate composition.
This document outlines a framework for assessing the externalities of nitrogen fertilizers. It discusses the benefits of nitrogen fertilizers, including higher crop yields, as well as downsides such as energy intensive manufacturing processes that are polluting. It then presents a methodology for quantifying emitted pollutants from nitrogen fertilizer production and application, such as carbon dioxide, nitrous oxide, ammonia, and particulate matter. The document monetizes these emissions using damage costs per ton reported by various studies. As an example, the environmental costs of nitrogen fertilizer use in UK agriculture is estimated to be 216 euros per hectare, or 36% of the sector's gross value added. Finally, the document discusses a two-track policy approach involving
This document summarizes a proposed research project called CESAR (Coastal Environment under Sargassum crisis). The project aims to provide knowledge and tools to help manage Sargassum influxes in the Caribbean region, particularly the French West Indies. It will involve monitoring and forecasting Sargassum distributions using satellite data and ocean models. The project is led by a consortium of research organizations and will have two work packages. The first will focus on satellite monitoring and developing forecasting capabilities, while the second will examine governance and policy related to Sargassum management. Expected results include improved detection algorithms, transport modeling of Sargassum, and policy recommendations to help decision makers address Sargassum
This document summarizes a proposed research project on integrating bioassays into assessments of aquatic ecosystem quality under the European Water Framework Directive. The project aims to gauge how combining standard ecological quality assessments with ecologically relevant bioassays can improve the ability to assess and manage European water bodies. It will focus on developing in situ bioassays using species found in the Mondego Estuary, and integrating the results of the bioassays with other monitoring data. Over summer and winter, a battery of in situ bioassays will be performed at sampling stations in the estuary using selected species. Water, sediment, and invertebrate data will also be collected. Multivariate tools will be used to integrate the bioassay results with
1. The document outlines steps for students to conduct field studies to understand ecosystems, including identifying abiotic and biotic components, investigating interactions between components, and studying processes like colonization and succession.
2. Students are instructed to identify trophic levels, study competition between species, and conduct experiments on topics like the effects of abiotic factors on population distribution.
3. Additional topics covered include the need for classification of organisms, the five kingdoms of life, and the importance of biodiversity. Students are to demonstrate understanding of these concepts.
Nanotoxicology is the study of the toxicity of nanomaterials. As the size of particles decreases, their surface area increases, allowing more of their atoms and molecules to interact with the environment and potentially cause toxic effects. Nanomaterials can enter the body through various routes and distribute to organs, where they may cause toxicity through effects like inflammation, DNA damage, and tissue damage. They may also pollute the environment through deposition in water, soil, and plants. Occupational, consumer, and environmental exposures are increasing as nanotechnology applications expand. The toxicity depends on factors like surface area, chemical composition, and ability to interact with and inhibit enzymes.
This document discusses GMOs and related issues including risks and regulations. It outlines both the advantages and disadvantages of GMOs, such as increased crop yields but also potential risks to human health and the environment. The document examines myths around GMOs and discusses controversies including safety, intellectual property access, ethics, and labeling. It also reviews principles of risk analysis for GMOs and biosafety guidelines and regulations in India and internationally. In conclusion, the author notes the field of biosafety is controversial but proponents see benefits while critics see risks that may be unacceptable without sufficient scientific certainty and precautions.
Center of Excellence on Climate Change Research for Plant Protection (CoE-CCRPP)ICRISAT
This document outlines the goals and objectives of the Center of Excellence on Climate Change Research for Plant Protection (CoE-CCRPP). The CoE-CCRPP aims to establish facilities and provide opportunities for research on the impact of climate change on diseases and insect pests affecting legumes. Its objectives are to analyze weather data and its relationship to pests and pathogens, evaluate crop resistance under climate change, and predict potential changes in the distribution and abundance of pests and diseases. The CoE-CCRPP will also work to standardize techniques to study interactions between crops, pests, pathogens and the environment in relation to climate variables and build capacity for climate change research.
1) Silver nanoparticles are intentionally produced engineered nanomaterials that are being used in many consumer products due to their antibacterial properties. However, there is concern about their potential impacts on human health and the environment.
2) The project aimed to develop methods to detect silver nanoparticles in water, determine their toxicological effects in aquatic environments, and develop risk assessment protocols.
3) Key findings included that activated charcoal can effectively capture silver nanoparticles from water, effects were observed on aquatic organisms in toxicity tests, and current models estimate low environmental concentrations pose low risks to human health through drinking water. However, more studies are needed to monitor silver nanoparticles in Ireland's environment and risks.
Neonicotinoids: The Science and Regulatory ComplexityCovance
The document provides an overview of neonicotinoids (neonics), a class of insecticides similar to nicotine. It discusses the history and rationale for their use in agriculture, their chemical properties and modes of action. It also reviews concerns about their effects on bees and other pollinators. The regulatory review process of neonics in the European Union is examined, including risk assessments by the European Food Safety Authority that led to restrictions on the use of imidacloprid, clothianidin and thiamethoxam due to risks to bees. The limitations and timeline of the regulatory process in the EU are outlined.
Antifouling wrap: a sustainable solutions for biofouling preventionlenses
The document discusses the development of Antifouling Wrap, a sustainable solution for biofouling prevention on ship hulls using nanotechnology and wrap strategies. It aims to develop environmentally friendly marine coatings that do not use biocides. The research tested various film materials on ship hull samples and found that a flocked PVC surface had fouling release and self-cleaning properties, reducing hull maintenance time by up to 80% compared to traditional paints. Future work will explore optimizing the film surface design and integrating antibacterial compounds to further improve the antifouling performance of the wrap solution.
Program for the rehabilitation and restoration presentation2 Maricar Onggon
This document outlines a program to rehabilitate mined out areas in the Philippines using phytotechnologies. It describes 3 projects, each led by a different project leader and focusing on: 1) conserving native metallophytes and testing phytostabilization in Palawan, Surigao, and Zambales, 2) identifying metal bioindicator species in 6 sites and creating a database, and 3) identifying copper and arsenic hyperaccumulators for potential post-mining metal recovery. The overall objectives are to study indigenous metallophyte species for phytotechnologies and develop protocols for their propagation and use in phytoremediation and post-mining activities.
This document summarizes the key points from a presentation on the safety and toxicity related to nanopharmaceuticals. It discusses nanotoxicology and some of the reasons nanoparticles can be toxic, such as their large surface area to volume ratio. It covers toxicological factors, routes of exposure including inhalation, skin contact and ingestion. Diseases associated with nanoparticles are mentioned. The document provides an overview of ensuring safety in nanopharmaceuticals through measures like material safety data sheets, personal protective equipment, safety engineering controls and proper disposal procedures. It concludes more research is still needed to understand nanoparticle toxicity and ensure safer materials can be developed.
The presentation shows how urban gardens that contain flowering perennial plants provide food, habitat, and sanctuary for native bees and other beneficial insects.
Letus Capital SA is a corporate finance advisory firm that provides services such as mergers and acquisitions advisory, capital raising, IPOs, and valuations. Some of their notable clients and projects include advising Integer.pl SA on their IPO and acquisition deals, advising PKN Orlen on a $500 million investment project, and advising Graal SA on their IPO and acquisition deals. Letus Capital has over 100 completed projects and experience advising companies across various industries. They transformed into a public company in 2008 when they debuted on NewConnect.
This document discusses the anatomy, physiology, imaging, and pathologies of the diaphragm. It describes the diaphragm's muscular origins and innervation. Normal chest x-rays show the diaphragm is 2-3 mm thick. Pathologies include diaphragmatic paralysis, ruptures from trauma, and hernias such as Bochdalek and Morgagni hernias. Tumors like leiomyosarcomas can also involve the diaphragm. Imaging plays a key role in evaluating diaphragmatic abnormalities.
The diaphragm develops from four sources in the embryo and matures to become a dome-shaped musculofibrous sheet that separates the thoracic and abdominal cavities. It has a central tendon to which muscular fibers attach and is the primary muscle of respiration. During inspiration, it contracts to flatten and lower, increasing the vertical space in the thorax. It has openings that allow structures like the esophagus, inferior vena cava and aorta to pass between the thorax and abdomen. The phrenic nerves provide motor innervation and allow the diaphragm to contract during breathing.
The diaphragm is a fibromuscular sheet that separates the thoracic cavity from the abdominal cavity. It has three parts - the sternal, costal, and vertebral parts. The diaphragm contracts during inspiration to increase the volume of the thoracic cavity. It receives motor innervation from the phrenic nerves and sensory innervation from intercostal and phrenic nerves. During development, the diaphragm forms from the septum transversum, pleuroperitoneal membranes, mesentery of the esophagus, and body wall mesoderm. Diseases affecting the diaphragm include hernias, paralysis, trauma, and tumors.
Honeybee castes include the queen bee, drones, and worker bees. The queen bee is the only fertile member of the hive and lays all the eggs. Her genetic traits can be passed on to offspring. Drones exist solely to mate with the queen in a sometimes fatal act. Worker bees perform all the activities to maintain the hive, such as building comb, foraging, and caring for the queen and larvae. A honeybee's diet determines whether it develops into a queen or worker, as queen larvae are fed exclusively royal jelly.
Design for Change: Empathy as our Guide: Amy Cueva Keynote at Partners Center...Amy Cueva
This presentation was a part of the "Design for Change" track at the October 29, 2015 Partners Center for Connected Health Symposium. The presentation discusses how Empathy can be our guide as we seek to improve health experiences.
Honey bees are crucial pollinators for many fruits and vegetables. They pollinate about 30% of the food consumed in the US. However, honey bee populations have declined by 30-50% over the last 20 years due to various factors like pesticides, malnutrition, mites, and viruses. If honey bee populations continue to decline, it could significantly impact food prices and availability. There are steps people can take to help honey bees, such as planting bee-friendly gardens and donating to research on solving colony collapse disorder.
The document summarizes the results from the APENET monitoring project in Italy that studied the effects of pesticides on bee health. Some key findings include:
1) Dust from maize seed sowing was found to disperse and deposit on the ground, exposing bees to pesticides even with modified drilling machines. Laboratory tests found damages to bee memory and colony strength from exposure.
2) The Italian Ministry of Agriculture renewed the suspension of 4 neonicotinoid pesticide active ingredients for seed treatment in 2010 based on APENET results.
3) Sublethal effects of pesticides were found to potentially impact colonies through synergistic effects, intoxication of foragers, and impaired brood development
This document discusses insect pest monitoring and surveillance. It provides 14 reasons for the economic importance of insects, including for medicine, scientific research, pollination, biological control, and as a food source. It then discusses pest monitoring, the importance of monitoring pest populations to inform integrated pest management, and different monitoring approaches like direct counts and traps. The document also covers pest surveillance, its objectives to track pest levels and distributions over time, and components like pest identification, weather assessment, and natural enemy monitoring. The goals of surveillance are outlined as detecting pest presence, monitoring population levels, studying weather impacts, and informing timely control measures.
Global bee colony_disorder_and_threats_insect_pollinatorsPatricio Crespo
1. Pollination is vital for many global food crops as over 70 crop species depend on animal pollinators like bees.
2. Studies show pollinator populations have been declining in recent decades due to factors like habitat loss and pesticides.
3. This raises concerns about a potential "pollinator crisis" and threats to food security as pollinators are important for crop production worldwide. Specific concerns include declining honey bee populations and stability of managed hives.
pheromone traps for assessment and monitoring محطة بحوث وقاية النباتات 2019.pptxAbdallah Albeltagy
The document discusses insecticide resistance in insect pests and proposes using pheromone traps as an alternative to conventional insecticide applications. It notes that heavy insecticide use has led to many insects developing resistance. Pheromone traps could be used to monitor insect populations and insecticide resistance over time without the environmental and financial costs of widespread insecticide spraying. The document then describes research conducted in Egypt using pheromone traps and an "attracticide resistance monitoring technique" to study the efficacy of insecticides against field strains of pink bollworm and detect any resistance development. Laboratory and field studies were carried out using various insecticides and pheromone traps to monitor susceptibility over time.
Understanding the Rearing of mosquito in laboratory and Mosquito Vector Surve...Muhammad Kamran (Sial)
This document summarizes four research projects:
1) A study on the tolerance of the American bollworm pest to Bt cotton, including experimental procedures to assess tolerance.
2) A mosquito survey in Sargodha, Pakistan that found the highest populations of Culex mosquitoes in the Y block area.
3) A project to understand mosquito rearing protocols and investigate the repellent effects of plant oils on Culex mosquitoes. Precautions and procedures for rearing mosquitoes in the laboratory are described.
4) References are listed but not described.
Pheromone traps for the estimating insecticides efficacyAbdallah Albeltagy
This document discusses using pheromone traps to assess insecticide efficiency and monitor insecticide resistance in field insect populations as an alternative to conventional insecticide applications. Pheromone traps provide a simple, quick and efficient technique compared to conventional methods that require large amounts of insecticides, sampling of crop fields and materials. Specifically, the document reviews the attracticide resistance monitoring technique which uses pheromone-baited traps treated with insecticides to monitor insecticide resistance in field populations with minimal time, cost and environmental impact compared to other methods.
This document summarizes a new product called SuperNemos, which is a formulation of beneficial nematodes that can be used as a natural alternative to chemical insecticides. SuperNemos is shown to be effective against a wide range of soil-dwelling insect pests. Independent studies found that SuperNemos achieved similar or better control than other nematode products and some chemical insecticides, but at lower application rates. SuperNemos offers growers an effective biopesticide option that is safer for the environment and human health compared to traditional chemical insecticides.
This document summarizes an upcoming workshop for a project to establish a Centre for Bee Diseases and Pests in Africa. The project aims to generate knowledge on bee diseases and pests across Africa in order to protect bee colonies, scale up honey production, and support pollination services for crop production. The workshop will bring together stakeholders from participating countries to discuss initial activities, including establishing research facilities in Kenya and four satellite stations in other countries, developing diagnostic tools and management modules, and strengthening capacities of farmers and institutions regarding bee health. The overall goal is to enhance awareness of bee health issues and create an enabling environment for improved control of diseases and pests in Africa.
The relevance of the farming community regarding zoonosesHarm Kiezebrink
During the EFSA’s Stakeholder Consultative meeting in Parma on Wednesday 29th and Thursday 30th June 2011, EFS interacted with the stakeholders on EFSA’s scientific activities and the outlook of the future activities involving the stakeholders. During the meeting Annette TOFT presented the opinion of the European farmers and agricultural cooperatives COPA – COGECA stressing the relevance of zoonoses questions to farmers and agri - cooperatives activities.
This document provides an overview of integrated pest management (IPM). It defines IPM as a pest management approach that uses multiple control strategies, including cultural, mechanical, biological and chemical tactics, to keep pest populations below economically damaging levels while minimizing risks to human health and the environment. The key principles of IPM include understanding pest biology and crop-pest interactions, advanced planning, balancing control costs and benefits, and monitoring pest populations to inform management decisions. The document discusses various IPM strategies and their advantages for improving farm profitability, reducing pest resistance and environmental impacts compared to reliance on pesticides alone.
This document provides an overview of integrated pest management (IPM). It defines IPM as a pest management approach that uses multiple control strategies, including cultural, mechanical, biological and chemical tactics, to keep pest populations below economically damaging levels while minimizing risks to human health and the environment. The key principles of IPM include understanding pest biology and crop-pest interactions, advanced planning, balancing control costs and benefits, and monitoring pest populations to inform management decisions. The document discusses various IPM strategies and their advantages for crop protection and sustainability over reliance on pesticides alone.
This document provides an overview of integrated pest management (IPM). It defines IPM as a pest management philosophy that uses all suitable techniques to keep pest populations below economically damaging levels while being environmentally sound and compatible with producer objectives. The document discusses why IPM is needed, its strategies like cultural controls, pesticides as a last resort, and monitoring economic thresholds. It also covers the principles of IPM like understanding crop-pest relationships, advanced planning, balancing control costs and benefits, and routine monitoring. Career opportunities in IPM are also mentioned.
1) The study examined the impacts of pesticides used in corn fields in Quebec on honeybee colonies. Experiments showed higher honeybee mortality and weaker hives in fields with moderate-to-high pesticide usage compared to low usage or control fields.
2) Laboratory analysis found that honeybees exposed to pesticides had increased levels of the enzyme acetylcholinesterase, indicating exposure. Biomarkers are being developed to better evaluate pesticide impacts on honeybee health.
3) Ongoing work includes measuring vitamin A and immune system enzymes in honeybees to study how pesticides may weaken immunity and facilitate viral infections.
This study tested the effects of two commercially available entomopathogenic nematodes used for biological pest control on bumble bees (Bombus terrestris). Both nematode products caused high mortality rates (≥80%) in bees within 96 hours of exposure to soil containing nematodes at the recommended field concentration. Of particular concern, one product containing a mixture of Heterorhabditis and Steinernema nematodes was able to proliferate in the carcasses of dead bees, potentially allowing infection of an entire bee colony or spread into the wider environment. The results suggest entomopathogenic nematodes sold for biological pest control pose a threat to bee populations.
This document discusses neonicotinoids, a class of neuro-active insecticides. It provides details on their development, mode of action, major compounds, uses in agriculture, and effects on pollinators. While neonicotinoids brought economic benefits, concerns emerged regarding their persistence in soils and potential role in pollinator declines. The EU has imposed restrictions on some neonicotinoids for agricultural use due to risks to pollinators.
This study investigated how pesticide exposure affects honey bee susceptibility to the gut parasite Nosema ceranae. The researchers collected pollen from honey bee hives in 7 crops to analyze pesticide content and exposure. They detected 35 different pesticides in the pollen samples, including 2 insecticides at levels above the median lethal dose. Bees fed pollen with higher fungicide loads were more likely to become infected with Nosema. The results suggest that fungicides and other agricultural chemicals can increase bees' susceptibility to pathogens even at sub-lethal levels.
Honey bee survival mechanisms against the parasiteHaloCantik
This document summarizes a literature review of 153 studies on honey bee survival mechanisms against the parasitic mite Varroa destructor. It finds that honey bee survival is largely explained by resistance mechanisms, including behaviors like grooming and hygienic removal of mite-infested brood. While many traits are involved, the studies identified no common molecular pathways for resistance or tolerance. Understanding how the different traits interact could help direct future research and breeding programs to develop bee populations that can survive without acaricide treatments.
Similar to Franz Streissl - Bee risk assessment (20)
Chris Lythgo - Semiochemicals: Current review programme - initial comments an...cropprotection
The document discusses some key issues with semiochemical active substance dossiers submitted for evaluation including:
1) A lack of detailed specifications and supporting analytical data for both active substances and impurities.
2) Sources of active substances are not always defined with specific plant locations.
3) Methods of manufacture are sometimes missing or lack detail.
4) Guidance on straight chain lepidopteran pheromones could be accepted except the trigger dose appears to be based on a personal communication rather than peer reviewed literature.
5) For other semiochemicals, comparisons to natural background levels need to be supported by measurable data from peer reviewed scientific literature.
Csaba Szentes - Micro-organisms: Part II: E-fate and ecotoxcropprotection
This document discusses the data requirements and potential data gaps for assessing the environmental fate and ecotoxicity of micro-organisms. It notes that experimental data are normally required unless an assessment can be made based on available information. Weak dossiers lacking data or sufficient justification from literature are identified as an issue. The key data requirements include information on persistence, mobility, effects on birds, aquatic organisms, bees, and other non-target organisms. Potential data gaps include a lack of data on natural background concentrations, persistence in water, and impacts of repeated applications over time.
Danièle Court Marques - Microorganisms - Part I: Toxicological Aspectscropprotection
The document discusses key issues regarding the toxicological assessment of microorganisms as part of Europe's review of ensuring safe food. Specifically, it raises questions about [1] the potential production of unknown secondary toxic metabolites during production, [2] how to assess risk from possible pathogenic contaminants in the absence of acceptable levels, and [3] the level of detail needed for analytical methods to identify strains.
1) The document outlines EFSA's work on developing guidance documents for estimating soil degradation rates, soil exposure concentrations, emissions from protected crop systems, and groundwater exposure assessments.
2) EFSA has published opinions and supporting documents on estimating soil degradation rates and soil exposure and is developing guidance documents on these topics for 2013-2014.
3) EFSA is also developing a new guidance document on estimating emissions from protected crop systems based on published opinions and reports, with the guidance foreseen for 2013.
4) EFSA received mandates from the European Commission for two opinions on the FOCUS groundwater report to evaluate lower and higher tier assessment recommendations, with opinions planned for adoption in 2013.
The document discusses the PPR Panel guidance on using probabilistic methodology to model dietary exposure to pesticide residues. It will provide guidance on how cumulative exposure varies across populations for acute and chronic exposure scenarios. It details basic and refined probabilistic modeling approaches and notes the guidance will be adopted in June 2012 after two public consultations. Next steps include EFSA developing more detailed guidance documents on specific scenarios in cooperation with the Commission and Member States.
This document discusses the Panel on Plant Protection Products' (PPR Panel) work on cumulative risk assessment of pesticides. It outlines the legislative background requiring consideration of cumulative and synergistic effects of pesticides. It describes the PPR Panel's past scientific opinions developing methodologies for cumulative assessment of pesticides with similar and dissimilar modes of action. It also lists current and planned activities, including developing guidance on probabilistic exposure modeling and identifying cumulative assessment groups of pesticides. Finally, it discusses emerging work on assessing cumulative exposure from non-dietary routes.
Hans Steinkellner - Metabolites for dietary risk assessmentcropprotection
The document discusses tools for assessing the toxicological relevance of pesticide metabolites for dietary risk assessment. It summarizes several EFSA projects evaluating the applicability of thresholds of toxicological concern, quantitative structure-activity relationships, and the impact of metabolism on toxicity for this purpose. The projects concluded that thresholds of toxicological concern are appropriate for assessing metabolite risk and that combinations of models may help determine genotoxicity. A draft scientific opinion will apply these tools in case studies and address uncertainties to derive acute and chronic exposure thresholds for metabolites.
Istvan Sebestyen - Workers operators bystanders and residentscropprotection
The document provides background on EFSA's efforts to develop guidance on pesticide exposure assessment. It summarizes EFSA's process of gathering input, conducting public consultations, and drafting the guidance document and related scientific opinion between 2006-2010. The main contents of the scientific opinion are outlined, including defining the scope, reviewing legal requirements, current risk assessment methods, and proposed new approaches for assessing acute risk and accounting for statistical variability.
Wolfgang Reinert - Guidance on guidance document developmentcropprotection
This document outlines a proposed guidance on developing guidance documents. It would define the process for creating and revising guidance documents, including establishing competencies, drafting steps, adoption procedures, and application dates. The guidance aims to improve quality, usefulness, and transparency by clarifying roles, avoiding duplication, and communicating the process to authorities and stakeholders. A stepwise approach is recommended that identifies needs, produces concept papers, allows for discussion and adoption, and publishes the final documents.
Luc Mohimont - Priorities of the PPR panelcropprotection
The PPR Panel is responsible for providing EFSA's scientific opinions on pesticides. Composed of 21 members with a 3-year renewable mandate, it is supported by working groups of external experts. The PPR Panel adopts scientific opinions, guidance documents, and statements on areas like human and environmental risk assessment of pesticides. It has adopted 58 opinions since 2004, including 41 on generic issues and guidance and 17 on specific compounds. Guidance development will increasingly be handled by EFSA working groups including PPR Panel experts. The PPR Panel has ongoing mandates through 2017 on topics like aquatic ecotoxicology and terrestrial ecotoxicology.
Aija Kazocina - Update on risk assessment of MRLscropprotection
The document provides an update on EFSA's progress in assessing maximum pesticide residue limits (MRLs) according to Articles 10 and 12 of Regulation (EC) No 396/2005. [1] EFSA is responsible for assessing new MRL proposals under Article 10 and reviewing existing MRLs under Article 12 to ensure they are safe for consumers. [2] From 2008-2012, EFSA assessed 432 new MRL applications under Article 10 and is ongoing in its review of existing MRLs for 167 substances approved before 2008 and 243 approved after under Article 12. [3] The document notes some priorities and challenges for applicants in the MRL assessment process.
Daniela Brocca - Pesticide residues in food: Monitoring programmes in Europe ...cropprotection
The document summarizes monitoring programs and findings related to pesticide residues in food in Europe. It discusses the legal framework for monitoring in EU countries, EFSA's annual reports on pesticide residues, and a new EU data collection system. The main findings from EFSA's 2009 annual report are that over 97% of samples did not exceed maximum residue levels, with exceedances more common in imported and unprocessed foods. EFSA also conducts cumulative risk assessments of pesticide residues.
IBMA input and EFSA/PSC response at industry meeting April 2012cropprotection
The document summarizes discussions between EFSA and IBMA on various topics related to the review of List 4 biocontrol substances. Key points included an update from EFSA on timelines for reviews, acknowledgment of the value of a post-assessment lessons learned document, and discussions around guidance documents, data requirements and waivers, consequences of delays, and handling of substances included in the Green Track process. EFSA advised that many of the issues raised would need to be addressed by risk managers or relevant expert groups.
Herman Fontier - Update on the evaluation of active substancescropprotection
This document summarizes Herman Fontier's presentation on the evaluation of active substances by the European Food Safety Authority (EFSA). The presentation discusses EFSA's peer review activities in 2011, including conclusions delivered. It also outlines the peer review planning for 2012 and beyond, implementation of Regulation (EC) No 1107/2009, and the process for commenting on draft EFSA conclusions.
EFSA provides independent scientific advice on food safety and nutrition issues to the European Commission, European Parliament, and EU member states. In 2013, EFSA predicted 676 scientific outputs to meet the continuing high demand for scientific advice. Key priorities included boosting risk assessment capacity, enhancing dialogue with risk managers, and improving efficiency. Major science highlights included providing scientific opinions on meat inspection modernization, dietary reference values, and assessments of genetically modified organisms, pesticides, and food contact materials.
1) The document provides industry's view on EFSA's contributions to pesticide regulation, including their processes for active substance peer reviews, establishing maximum residue levels (MRLs), and scientific guidance.
2) While timelines are generally respected, industry finds some EFSA comments on active substance evaluations arrive too late and there are limitations on submitting new information.
3) Guidelines for MRL reasoned opinions are followed predictably but outcomes are sometimes viewed as conservative.
4) The annual MRL report is considered very useful but guidance documents are seen as sometimes disconnected from use contexts and imposing unnecessarily complex or conservative standards.
The document discusses several issues related to evaluating the safety of botanical active substances for use in plant protection products and biocides. It notes limited toxicology data available for many botanicals due to a lack of standardized testing methods. It also raises questions around defining the identity of active substances in botanicals and ensuring representative marker compounds are used in required studies.
This document discusses sustainability in the EU food and drink industry. It notes that the industry purchases 70% of EU agricultural produce and is the largest agricultural importer globally, relying on stable supplies of high quality raw materials. It highlights challenges like climate change, population growth, and resource scarcity putting pressure on food security. The document advocates for reducing waste, promoting industrial symbiosis, and cooperation across the food chain to develop sustainable solutions through roundtable discussions. It stresses the importance of securing raw materials sustainably to support the EU economy and food supply.
Biodiversity is important for agricultural production, which needs to grow to meet rising global food demands. Crop losses from pests and diseases average around 25% worldwide, showing the need to minimize these impacts through better use of pesticides and practices that work with the environment's natural pest control abilities rather than against them.
Sustainable food and environment is about science based decision making for nourished by technology. The document discusses sustainable food and the environment from the perspective of Julie Girling, a Member of European Parliament.
In the rapidly evolving landscape of technologies, XML continues to play a vital role in structuring, storing, and transporting data across diverse systems. The recent advancements in artificial intelligence (AI) present new methodologies for enhancing XML development workflows, introducing efficiency, automation, and intelligent capabilities. This presentation will outline the scope and perspective of utilizing AI in XML development. The potential benefits and the possible pitfalls will be highlighted, providing a balanced view of the subject.
We will explore the capabilities of AI in understanding XML markup languages and autonomously creating structured XML content. Additionally, we will examine the capacity of AI to enrich plain text with appropriate XML markup. Practical examples and methodological guidelines will be provided to elucidate how AI can be effectively prompted to interpret and generate accurate XML markup.
Further emphasis will be placed on the role of AI in developing XSLT, or schemas such as XSD and Schematron. We will address the techniques and strategies adopted to create prompts for generating code, explaining code, or refactoring the code, and the results achieved.
The discussion will extend to how AI can be used to transform XML content. In particular, the focus will be on the use of AI XPath extension functions in XSLT, Schematron, Schematron Quick Fixes, or for XML content refactoring.
The presentation aims to deliver a comprehensive overview of AI usage in XML development, providing attendees with the necessary knowledge to make informed decisions. Whether you’re at the early stages of adopting AI or considering integrating it in advanced XML development, this presentation will cover all levels of expertise.
By highlighting the potential advantages and challenges of integrating AI with XML development tools and languages, the presentation seeks to inspire thoughtful conversation around the future of XML development. We’ll not only delve into the technical aspects of AI-powered XML development but also discuss practical implications and possible future directions.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
HCL Notes und Domino Lizenzkostenreduzierung in der Welt von DLAUpanagenda
Webinar Recording: https://www.panagenda.com/webinars/hcl-notes-und-domino-lizenzkostenreduzierung-in-der-welt-von-dlau/
DLAU und die Lizenzen nach dem CCB- und CCX-Modell sind für viele in der HCL-Community seit letztem Jahr ein heißes Thema. Als Notes- oder Domino-Kunde haben Sie vielleicht mit unerwartet hohen Benutzerzahlen und Lizenzgebühren zu kämpfen. Sie fragen sich vielleicht, wie diese neue Art der Lizenzierung funktioniert und welchen Nutzen sie Ihnen bringt. Vor allem wollen Sie sicherlich Ihr Budget einhalten und Kosten sparen, wo immer möglich. Das verstehen wir und wir möchten Ihnen dabei helfen!
Wir erklären Ihnen, wie Sie häufige Konfigurationsprobleme lösen können, die dazu führen können, dass mehr Benutzer gezählt werden als nötig, und wie Sie überflüssige oder ungenutzte Konten identifizieren und entfernen können, um Geld zu sparen. Es gibt auch einige Ansätze, die zu unnötigen Ausgaben führen können, z. B. wenn ein Personendokument anstelle eines Mail-Ins für geteilte Mailboxen verwendet wird. Wir zeigen Ihnen solche Fälle und deren Lösungen. Und natürlich erklären wir Ihnen das neue Lizenzmodell.
Nehmen Sie an diesem Webinar teil, bei dem HCL-Ambassador Marc Thomas und Gastredner Franz Walder Ihnen diese neue Welt näherbringen. Es vermittelt Ihnen die Tools und das Know-how, um den Überblick zu bewahren. Sie werden in der Lage sein, Ihre Kosten durch eine optimierte Domino-Konfiguration zu reduzieren und auch in Zukunft gering zu halten.
Diese Themen werden behandelt
- Reduzierung der Lizenzkosten durch Auffinden und Beheben von Fehlkonfigurationen und überflüssigen Konten
- Wie funktionieren CCB- und CCX-Lizenzen wirklich?
- Verstehen des DLAU-Tools und wie man es am besten nutzt
- Tipps für häufige Problembereiche, wie z. B. Team-Postfächer, Funktions-/Testbenutzer usw.
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Sudheer Mechineni, Head of Application Frameworks, Standard Chartered Bank
Discover how Standard Chartered Bank harnessed the power of Neo4j to transform complex data access challenges into a dynamic, scalable graph database solution. This keynote will cover their journey from initial adoption to deploying a fully automated, enterprise-grade causal cluster, highlighting key strategies for modelling organisational changes and ensuring robust disaster recovery. Learn how these innovations have not only enhanced Standard Chartered Bank’s data infrastructure but also positioned them as pioneers in the banking sector’s adoption of graph technology.
For the full video of this presentation, please visit: https://www.edge-ai-vision.com/2024/06/building-and-scaling-ai-applications-with-the-nx-ai-manager-a-presentation-from-network-optix/
Robin van Emden, Senior Director of Data Science at Network Optix, presents the “Building and Scaling AI Applications with the Nx AI Manager,” tutorial at the May 2024 Embedded Vision Summit.
In this presentation, van Emden covers the basics of scaling edge AI solutions using the Nx tool kit. He emphasizes the process of developing AI models and deploying them globally. He also showcases the conversion of AI models and the creation of effective edge AI pipelines, with a focus on pre-processing, model conversion, selecting the appropriate inference engine for the target hardware and post-processing.
van Emden shows how Nx can simplify the developer’s life and facilitate a rapid transition from concept to production-ready applications.He provides valuable insights into developing scalable and efficient edge AI solutions, with a strong focus on practical implementation.
Essentials of Automations: The Art of Triggers and Actions in FMESafe Software
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Climate Impact of Software Testing at Nordic Testing DaysKari Kakkonen
My slides at Nordic Testing Days 6.6.2024
Climate impact / sustainability of software testing discussed on the talk. ICT and testing must carry their part of global responsibility to help with the climat warming. We can minimize the carbon footprint but we can also have a carbon handprint, a positive impact on the climate. Quality characteristics can be added with sustainability, and then measured continuously. Test environments can be used less, and in smaller scale and on demand. Test techniques can be used in optimizing or minimizing number of tests. Test automation can be used to speed up testing.
Why You Should Replace Windows 11 with Nitrux Linux 3.5.0 for enhanced perfor...SOFTTECHHUB
The choice of an operating system plays a pivotal role in shaping our computing experience. For decades, Microsoft's Windows has dominated the market, offering a familiar and widely adopted platform for personal and professional use. However, as technological advancements continue to push the boundaries of innovation, alternative operating systems have emerged, challenging the status quo and offering users a fresh perspective on computing.
One such alternative that has garnered significant attention and acclaim is Nitrux Linux 3.5.0, a sleek, powerful, and user-friendly Linux distribution that promises to redefine the way we interact with our devices. With its focus on performance, security, and customization, Nitrux Linux presents a compelling case for those seeking to break free from the constraints of proprietary software and embrace the freedom and flexibility of open-source computing.
AI 101: An Introduction to the Basics and Impact of Artificial IntelligenceIndexBug
Imagine a world where machines not only perform tasks but also learn, adapt, and make decisions. This is the promise of Artificial Intelligence (AI), a technology that's not just enhancing our lives but revolutionizing entire industries.
GraphSummit Singapore | The Future of Agility: Supercharging Digital Transfor...Neo4j
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This keynote will reveal how Deloitte leverages Neo4j’s graph power for groundbreaking digital twin solutions, achieving a staggering 100x performance boost. Discover the essential role knowledge graphs play in successful generative AI implementations. Plus, get an exclusive look at an innovative Neo4j + Generative AI solution Deloitte is developing in-house.
Threats to mobile devices are more prevalent and increasing in scope and complexity. Users of mobile devices desire to take full advantage of the features
available on those devices, but many of the features provide convenience and capability but sacrifice security. This best practices guide outlines steps the users can take to better protect personal devices and information.
UiPath Test Automation using UiPath Test Suite series, part 6DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 6. In this session, we will cover Test Automation with generative AI and Open AI.
UiPath Test Automation with generative AI and Open AI webinar offers an in-depth exploration of leveraging cutting-edge technologies for test automation within the UiPath platform. Attendees will delve into the integration of generative AI, a test automation solution, with Open AI advanced natural language processing capabilities.
Throughout the session, participants will discover how this synergy empowers testers to automate repetitive tasks, enhance testing accuracy, and expedite the software testing life cycle. Topics covered include the seamless integration process, practical use cases, and the benefits of harnessing AI-driven automation for UiPath testing initiatives. By attending this webinar, testers, and automation professionals can gain valuable insights into harnessing the power of AI to optimize their test automation workflows within the UiPath ecosystem, ultimately driving efficiency and quality in software development processes.
What will you get from this session?
1. Insights into integrating generative AI.
2. Understanding how this integration enhances test automation within the UiPath platform
3. Practical demonstrations
4. Exploration of real-world use cases illustrating the benefits of AI-driven test automation for UiPath
Topics covered:
What is generative AI
Test Automation with generative AI and Open AI.
UiPath integration with generative AI
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
UiPath Test Automation using UiPath Test Suite series, part 6
Franz Streissl - Bee risk assessment
1. Request of the EU Commission
for an Opinion on the science behind the development
of a risk assessment of PPPs on bees (Apis mellifera
Bombus spp. and solitary bees)
and to prepare an EFSA Guidance on the risk
assessment of PPPs on bees.
ECPA-IBMA workshop – EFSA evaluation of PPPs
26 April 2012 1
2. Bee mandate M-2011-0185
• EFSA-Q-2011-00417: Scientific Opinion on the science behind the
development of a Risk Assessment of Plant Protection Products on
bees (Apis mellifera, Bombus spp. and solitary bees).
• EFSA-Q-2011-00418: Guidance Document on the Risk Assessment
of Plant Protection Products on bees (including Apis mellifera,
Bombus spp. and solitary bees).
• EFSA-Q-2011-00794: Public consultation on the draft Guidance
Document on the Risk Assessment of Plant Protection Products on
bees (including Apis mellifera, Bombus spp. and solitary bees).
2
3. Bee mandate M-2011-0185
Composition of the working group:
• 4 members of PPR Panel (expertise in pesticide risk assessment,
uncertainty analysis, fate and behaviour of pesticides, probabilistic risk
asessment)
• 4 experts in honeybee biology (one beekeeper) (expertise in all aspects
of honeybee biology, test methods, exposure, monitoring)
• 2 experts in bumblebee and solitary bee biology (expertise in all aspects
of non-Apis bee biology, monitoring, test methods)
• 1 hearing expert from Industry (only invited to give information to the
group but no active involvement)
• 4 EFSA staff members (expertise in pesticide risk assessment, bee
biology/behaviour, toxicology)
3
4. Bee mandate M-2011-0185
Terms of reference:
• The Guidance Document should address the risk to Apis mellifera,
Bombus spp and to solitary bees.
• The assessment of the acute and chronic effects of Plant Protection
Products on bees, including the colony survival and development.
• The estimation of the long term effects due to exposure to low
concentrations.
• The development of a methodology to take into account cumulative and
synergistic effects.
• The evaluation of the existing validated test protocols and the possible
need to develop new protocols, especially to take into account the
exposure of bees to pesticides through nectar and pollen.
4
5. Bee mandate M-2011-0185
Chapters of the opinion:
1. Introduction
2. Specific protection goals
3. Exposure
4. Chronic toxicity of pesticides in bees after continuous
exposure at low (sub-lethal) doses
5. The evaluation of the existing test protocols for honeybees,
social non-Apis (bumblebees) and solitary bees
(laboratory/semi-field/field)
6. How to take into account cumulative and synergistic effects
7. Risk assessment for honeybees, bumblebees and solitary
bees
8. Conclusions and recommendations 5
6. Bee mandate M-2011-0185
Chapter 2: Specific protection goals (SPG)
Follows the approach outlined in the Scientific Opinion of EFSA (2010) on
the definition of specific protection goals.
Ecosystem services to protect:
1. Pollination
2. Food production (hive products)
3. Genetic resources and cultural services (education, aesthetic, recreation)
Ecological entity:
Apis mellifera: colony for all SPGs, foragers for pollination
Non-Apis – population (colonies for bumblebees)
6
7. Bee mandate M-2011-0185
Chapter 2: Specific protection goals (SPGs)
Attributes to protect:
EU regulation (EC) No 1107/2009 lists acute and chronic effects on the
survival and development of colonies and effects on larvae and honey bee
behaviour as attributes to protect. It is suggested to include also
abundance/biomass and reproduction because they are important for long-term
survival of the colony.
Magnitude of effects:
Small effects on foragers in field (in the range of days), negligible effects off-
field, negligible effects on colonies (at the field edge).
Exposure assessment goals:
The overall level of protection includes also the exposure assessment goal.
7
8. WG Bee risk assessment
Chapter 2: Specific protection goals (SPGs)
Exposure assessment goals:
Consider each of the regulatory zones as the total area for all SPGs.
Focus on the field scale to avoid “dilution” of the spatial population with a large
fraction of e.g. unexposed hives.
95th percentile of the spatio-temporal concentration distribution is used as a
working hypothesis (90th percentiles were accepted in the past but may not be
conservative enough).
8
9. WG Bee risk assessment
Chapter 2: Specific protection goals (SPGs)
Exposure assessment goals:
Current risk assessment relies on HQ approach and semi-field and field tests.
Difficult to ascertain that a specific exposure percentile is achieved. Flow chart
for checking whether exposure in semi-field or field study was higher than the
corresponding 95th percentile. These main factors could include:
• Crop and development stage in study in relation to agricultural reality
• Dosage in study and in reality
• Measures taken in the study to ensure exposure
• Location and weather conditions in the study compared to zone for which the
risk assessment is carried out
• Generation of guttation water in the study compared to reality
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10. Bee mandate M-2011-0185
Chapter 3: Exposure
Major exposure routes (oral, contact, inhalation) were identified for honeybees,
bumblebees and solitary bees for sprayed, non-sprayed (systemic and non-
systemic) substances and for soil fumigants.
Information was collected on consumption of nectar, pollen, water,
interception of droplets of different life stages of honeybees (foragers, wax
producing bees, nurse bees, winter bees, drones queens, swarms, larvae),
bumblebees (workers, drones, queens, larvae) and solitary bees (adult male, adult
female, larvae).
Information was collected on residues in nectar, pollen, water, honey, bee
bread, nesting material (wax, propolis, resins), soil and plant surfaces.
Based on the information retrieved and expert judgement the most exposed
categories of bees were identified by expert judgement.
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11. Bee mandate M-2011-0185
Chapter 3: Exposure
Honeybees:
Foraging bees, winter bees and larvae were most exposed via the oral route.
Larvae were most exposed to residues in wax and foragers, drones, queens and
swarms were most exposed to interception of droplets and vapour (contact and
inhalation exposure).
Bumblebees:
Workers, queens and larvae were most exposed via oral route and also via
contact and inhalation (nest in soil).
Solitary bees:
Adult females and larvae were most exposed via oral route. Adult and larvae
show maximum exposure to soil and foliar residues (nesting material).
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12. Bee mandate M-2011-0185
Chapter 3: Exposure
Water consumption was unknown and therefore it was not possible to give an
estimate on the relative importance of exposure to residues in water.
A potential high exposure to guttation droplets was highlighted for certain
crops (e.g. maize). The potential risk to bees depends on the distance between
the colony and the crop and the availability of alternative sources of water and
the frequency (e.g. the risk could be high if a crop is treated with a highly bee
toxic compound, the crop shows guttation activity frequently and the colony is
close to the crop).
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13. Bee mandate M-2011-0185
Chapter 3: Exposure
Dust drift can lead to relevant exposure during sowing of treated seeds or
application of granular formulations due to deposition of dust particles on the
soil in the field, soil and plants outside the field, on puddles in the field,
interception of particles by flying bees, particles entering the hive via air
exchange.
The level of exposure of bees is extremely variable and depends on the quality
of the seed dressing (abrasion), machinery used, number of seeds per ha, time of
sowing, size of the sown area, the vegetation in the margin of the field and on the
meteorological conditions.
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14. Bee mandate M-2011-0185
Chapter 4: Chronic toxicity of pesticides in bees after
continuous exposure at low (sub-lethal) doses
Concerns were raised that biologically persistent toxins will have cumulative
effects that are disproportionate to their short-term manifestations.
The conventional regulatory tests are likely to be unsuited to assess the risks of
long-term exposures because they are short-term (48-96 h), which means that
they could fail to detect the true potential for harm.
A new method is proposed to detect cumulative toxicity based on Haber`s
law.
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15. Bee mandate M-2011-0185
Chapter 4: Chronic toxicity of pesticides in bees after
continuous exposure at low (sub-lethal) doses
Overview on the available studies on low doses and long-term effects of
pesticides on bees highlighted gaps in knowledge and future research needs.
For honeybees, more studies are required on a wider range of pesticides, on
larvae, on both low-doses and long-term effects (most studies deal with low
dose only), on exposure through contact and inhalation (most studies deal with
oral exposure), in field conditions (most studies are conducted under laboratory
conditions) and more studies are needed on endpoints such as biochemical and
neurophysiological effects, fecundity and longevity.
For non-Apis bees, few studies are available in literature and they involved only
few species. The use of micro-colonies in bumblebees appears to be well-suited
to measure lethal and sublethal effects of pesticides with low doses and long-
term effects. 15
16. Bee mandate M-2011-0185
Chapter 5: The evaluation of the existing test protocols
Laboratory tests
Oral and contact exposure of adult bees following OECD 213 and 214 guidelines.
Intermittent and prolonged exposure of adults and larvae testing is not included.
It is recommended in the first tier to include chronic testing of adult bees, a
laboratory test on larval toxicity test and precise observations of sublethal
effects (to be included in future risk assessment).
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17. Bee mandate M-2011-0185
Chapter 5: The evaluation of the existing test protocols
Semi-field tests
Semi-field testing follows the test guidelines of EPPO 170(4), OECD 75 (bee
brood) and Oomen et al. (1992) test (bee brood).
Several weaknesses were identified for each of the guidelines, e.g. the limited
size of crop area, limited duration of the studies (one brood cycle), difficult to
extrapolate results to larger colony sizes.
It is recommended to include a more detailed assessment of behavioural
effects, investigation of sublethal and delayed effects and to develop methods
to investigate in particular systemic compounds including exposure to dust and
guttation droplets. Results should be analysed with appropriate statistical
methods.
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18. Bee mandate M-2011-0185
Chapter 5: The evaluation of the existing test protocols
Field tests for honeybees
Field testing follows the guidelines of EPPO 170.
Several weaknesses were identified such as the small distance between the hives
and the treated fields, the low surface of the test field, uncertainties with regard to
the real exposure of honeybees. Not enough replicates to conduct a statistical
analysis.
It is recommended to develop guidelines adapted to the specific application of
a substance (e.g. also covering all important exposure routes for seed treatments)
and to investigate different effects e.g. homing flight, orientation, foraging
behaviour. The health status of the colonies needs to be assessed, increased
distance between controls and test fields, test design should allow statistical
analysis.
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19. Bee mandate M-2011-0185
Chapter 6: How to take into account of cumulative and
synergistic effects
This chapter aims to review the evidence of cumulative and synergistic effects of
pesticide mixtures in bees and to develop recommendations for risk assessment
purposes.
At low levels of exposure concentration addition has been observed more often
than synergistic or antagonistic effects for mixtures of pesticides with a common
mode of action.
Independent action (response addition) has been observed for compounds with a
different mode of action.
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20. Bee mandate M-2011-0185
Chapter 6: How to take into account of cumulative and
synergistic effects
The mechanism of synergistic effects involve inhibition or induction of either
detoxification enzymes (cytochrome P-450) or transporters which then
enhancing the toxicity of the mixture.
From available literature there is an indication that deviations from
concentration addition, such as synergy is rarely more than a factor of 2 to 3.
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21. Bee mandate M-2011-0185
Chapter 7: How to take into account of cumulative and
synergistic effects
In the case of synergism which can be predicted based on the mode of action of
the chemicals involved (e.g. EBI fungicides and insecticides) and in the absence
of data on the toxicity of the mixture it is recommended to design full dose-
response studies in adult bees and larvae for these mixtures of potential
synergists to provide a basis to derive benchmark doses and their limit as
suggested by EFSA`s scientific committee.
There is growing evidence that there are interactions between bee diseases and
pesticide effects. Further work is required to identify the molecular basis of
interactions between environmentally realistic exposure to pesticides and the
range of honeybee diseases to determine whether and how these may be included
in the risk assessment.
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22. Bee mandate M-2011-0185
Chapter 7: Risk assessment for honeybees, bumblebees and
solitary bees
Two new risk assessment schemes are proposed, one for honeybees and one for
bumblebees and solitary bees.
The most important exposure routes are covered:
Exposure of foragers by spray or dust by contact or oral intake, exposure of
all adult bees and larvae from exposure to residues in pollen, nectar or
guttation droplets.
Toxicity testing over longer exposure period for adult bees and larvae is
included in the first tier.
Investigation of cumulative effects.
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23. Bee mandate M-2011-0185
Chapter 7: Risk assessment for honeybees, bumblebees and
solitary bees
A 7 day laboratory larvae test (Aupinel) is always required. The Oomen test is
required if the LD50 for adult bees is below 100 µg/bee or the laboratory larvae
test gives an indication of cumulative toxicity. The Oomen test integrates brood
care behaviour of adult bees. The lower endpoint of both tests should be used in
the scheme.
The scheme for bumblebees and solitary bees is based on less well defined
steps and toxicity tests. The scheme uses data for honey bees as a surrogate
input. The development of standardized contact and oral toxicity test, semi field
and field tests for bumblebees and solitary bees has yet to be completed and ring
tested.
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24. Bee mandate M-2011-0185
Timelines:
Opinion to be issued by April 2012
Guidance Document to be issued by December 2012
Public consultation on draft GD:
July 2012 – September 2012
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