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Food for Fortification.
Anencephaly is a disease that could be prevented if flour was fortified with vitamin B9 (1)
The UK government,aswithanygovernment,receivesalotof negative attentionabouttrivial laws
and illogical budgetcuts,butperhaps the mostworryingissuesthatmakesthe headlinesare those
concerninghealthcare.Recently,the suggestionthata national programme formeningitisB
vaccineswasturneddowndue to poor“cost-effectiveness”,butthisisnotthe onlydecision
concerninghealththathascausedsome controversy.Inthe past yearalone twovitamindeficiencies
have beendiscussedbymedical authoritiesandgovernmenthealthdepartmentsalike,andeach
time nopositive actionhasbeentakentoresolve the issuesassociatedwiththe vitamindeficiencies.
These vitaminsare vitaminB9(a.k.a.folate,folicacid),andvitaminD,andtheyare causingsevere
healthproblemsinthe UK.
VitaminB9deficiencycausesmanyissuesforadultsufferers,includingthe extreme fatigue and
weaknessassociatedwithfullydevelopedperniciousanaemia.However,the mainconcerns
surroundingvitaminB9focuson the firstfew weeksof pregnancy,whenthe brainandspine of the
foetusstartto form,becomingdistinctorgans.A lackof vitaminB9duringthistime periodprevents
thisdevelopmentfromoccurringnormally,leadingtoanencephaly,aspicturedabove, spinabifida,
spontaneousterminationof pregnancies,stillbirths,andinfantdeaths(2).Any of these conditions
are highlydistressing,especiallyasanencephalyisalmostinvariablyfatal,andspinabifidaleadsto
lifelongdisability.Itisthereforerecommendedthatwomenplanningpregnanciesshouldtake folate
supplementsfromthree monthspriortoconception,to12 weeksintothe pregnancy,the onlyissue
of course,beingthatmanypregnanciesare unplanned,andsosupplementationcannotbe relied
uponto prevent anencephalyandspinabifida (3). Manystudieshave shownthatthe mosteffective
wayof preventingthesediseasesistofortifyflourwithvitaminB9,meaningthatenoughB9may be
available toall women atthe start of anypregnancy,plannedorotherwise, promotinghealthybrain
and spine development forthe foetus. However,despitethe factthat thistype of fortificationhas
beensuccessfully undertakenin77 differentcountries,thatthe ScientificAdvisoryCommitteeon
Nutrition(SACN)supportsfortification(4),andthatthere hasbeena 35% reductioninthe number
of casesof anencephalyandspinabifidasince the USA beganfortifyingflour(5),the British
governmentseemsreluctanttotake anyactionat all. Many people,myself amongthem, findsthis
decisionbaffling,andotherssimplyfindthisinfuriating.
Unfortunately,vitaminB9isnot the onlyvitamindeficiencyto be causingproblemsinthe UK; there
isalso a profoundissue withvitaminD.Thisvitaminisoftenreferredtoasthe “sunshine vitamin”,
due to the fact that upondirectexposure tosunlight,the skinisable tocreate vitaminD.However,
the lowlevels of sunlightduringwinterputthe UK populationatriskof vitaminDdeficiency,and
since there are fewfoodsrichinvitaminD (oilyfishandeggyolkcontainsthe most),the vitaminD
intake of anyone livinghere isoftenlow.Thisissue isincreasedwhensunscreenisusedheavily,or
whenskiniscovereddue tothe cold,or religiousrequirements,asthe intake fromsunlightisfurther
restricted(6).DeficiencyinvitaminDmostfamouslyleadstoricketsinchildren,andasimilardisease
inadultscalledosteomalacia.There isalsoapositive associationof deficiencywithfracture risk,and
otherpossible benefitsinclude areductioninthe riskof cancer,infections,autoimmune diseases,
dementia,andevenautism(6).The efficacyof supplementsconcerningthisdeficiencyisdisputed,
althoughsupplementationisrecommendedforpregnantorbreast-feedingwomen,andthose who
have little exposure todirectsunlight(i.e.night-shiftworkers,office workers) (7).Ithastherefore
beensuggestedthatfortifyingparticularfoodswithvitaminDwouldbenefitthiswidespreadissue,
especially foodsrichincalcium,whichwouldimprove bothvitaminDandcalciumabsorptionfrom
food,as done inthe USA. Milkis mandatorilyfortified,andbreakfastcereals,yogurtsandorange
juice maybe fortifiedif the manufacturerwishesto inAmerica.Incomparison,some breakfast
cereals,andsome margarinesare fortifiedwithvitaminD,andnone isaddedto milk inthe UK (8).
Once again,many well-respectedauthorities suchasSACN have suggestedthatthe fortificationof
foodswithvitaminDwouldbe extremelybeneficial, butthe governmenthas still chosentoignore
thisadvice.
Why fortificationprogrammeshave notbeenundertaken bythe UK governmentisbeyond
comprehensiontothose whounderstandthe positive impactitwouldhave onanyone livinginthe
UK. Disease isanissue thateveryone hascome intocontact withintheirlifetime,andmanyknow of
the devastationthatitleavesbehind.Whythen,whenlivescouldbe saved,the qualityof those lives
couldbe improved,andthe NHSwouldsave moneyontreatingthese conditions,isthisissue so
blatantlydisregardedbythose whohave the powertomake changes?
By Emma Steer, 2nd
yearBSc Nutrition.
References:
(1) Novielli C,2014, RememberingGrayson:AnencephalicBabyFacebookBannedWhose Life
ImpactedsoMany [online],date accessed[13/03/2016],URL
[http://www.lifenews.com/2014/03/03/remembering-grayson-anencephalic-baby-
facebook-banned-whose-life-impacted-so-many/]
(2) Morris J.K,RankinJ,KurinczukJ.J,SpringettA,TuckerD, WellesleyD,WreyfordB,WaldN.J,
2015, Preventionof neural tube defectsin the UK:a missedopportunity,Archivesof Disease
inChildhood[online],date accessed[13/03/2016],URL
[http://adc.bmj.com/content/early/2015/11/13/archdischild-2015-309226.abstract]
(3) FoodStandardsAgency,2016, Folicacid fortification [online],date accessed[13/03/2016],
URL [https://www.food.gov.uk/northern-ireland/nutritionni/folic-acid]
(4) BBC News,2015, Folicacidto fortifyflour'wouldcutbirthdefects' [online],date accessed
[13/03/2016], URL [http://www.bbc.co.uk/news/health-35122699]
(5) Centers forDisease Control andPrevention(USA),2015, Folicacidfortificationcontinuesto
preventneural tube defect [online],date accessed[13/03/2016], URL
[http://www.cdc.gov/ncbddd/folicacid/features/folicacid-prevents-ntds.html]
(6) ButtrissJ.L,2015, VitaminD:Sunshine vs.dietvs.pills,NutritionBulletin(BritishNutrition
Foundation) [online],volume 40,issue 4, pages279 – 285, date accessed[13/03/2016], URL
[http://onlinelibrary.wiley.com/doi/10.1111/nbu.12172/pdf]
(7) NHS Choices,2015, VitaminD[online],date accessed[13/03/2016], URL
[http://www.nhs.uk/Conditions/vitamins-minerals/Pages/Vitamin-D.aspx#]
(8) UnitedStatesDepartmentof HealthandHumanServics,2014, VitaminD[online],date
accessed[13/03/2016], URL [https://ods.od.nih.gov/factsheets/VitaminD-
HealthProfessional/#h4]

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Food for Fortification

  • 1. Food for Fortification. Anencephaly is a disease that could be prevented if flour was fortified with vitamin B9 (1) The UK government,aswithanygovernment,receivesalotof negative attentionabouttrivial laws and illogical budgetcuts,butperhaps the mostworryingissuesthatmakesthe headlinesare those concerninghealthcare.Recently,the suggestionthata national programme formeningitisB vaccineswasturneddowndue to poor“cost-effectiveness”,butthisisnotthe onlydecision concerninghealththathascausedsome controversy.Inthe past yearalone twovitamindeficiencies have beendiscussedbymedical authoritiesandgovernmenthealthdepartmentsalike,andeach time nopositive actionhasbeentakentoresolve the issuesassociatedwiththe vitamindeficiencies. These vitaminsare vitaminB9(a.k.a.folate,folicacid),andvitaminD,andtheyare causingsevere healthproblemsinthe UK. VitaminB9deficiencycausesmanyissuesforadultsufferers,includingthe extreme fatigue and weaknessassociatedwithfullydevelopedperniciousanaemia.However,the mainconcerns surroundingvitaminB9focuson the firstfew weeksof pregnancy,whenthe brainandspine of the foetusstartto form,becomingdistinctorgans.A lackof vitaminB9duringthistime periodprevents thisdevelopmentfromoccurringnormally,leadingtoanencephaly,aspicturedabove, spinabifida, spontaneousterminationof pregnancies,stillbirths,andinfantdeaths(2).Any of these conditions are highlydistressing,especiallyasanencephalyisalmostinvariablyfatal,andspinabifidaleadsto lifelongdisability.Itisthereforerecommendedthatwomenplanningpregnanciesshouldtake folate supplementsfromthree monthspriortoconception,to12 weeksintothe pregnancy,the onlyissue of course,beingthatmanypregnanciesare unplanned,andsosupplementationcannotbe relied uponto prevent anencephalyandspinabifida (3). Manystudieshave shownthatthe mosteffective wayof preventingthesediseasesistofortifyflourwithvitaminB9,meaningthatenoughB9may be available toall women atthe start of anypregnancy,plannedorotherwise, promotinghealthybrain and spine development forthe foetus. However,despitethe factthat thistype of fortificationhas beensuccessfully undertakenin77 differentcountries,thatthe ScientificAdvisoryCommitteeon Nutrition(SACN)supportsfortification(4),andthatthere hasbeena 35% reductioninthe number of casesof anencephalyandspinabifidasince the USA beganfortifyingflour(5),the British governmentseemsreluctanttotake anyactionat all. Many people,myself amongthem, findsthis decisionbaffling,andotherssimplyfindthisinfuriating.
  • 2. Unfortunately,vitaminB9isnot the onlyvitamindeficiencyto be causingproblemsinthe UK; there isalso a profoundissue withvitaminD.Thisvitaminisoftenreferredtoasthe “sunshine vitamin”, due to the fact that upondirectexposure tosunlight,the skinisable tocreate vitaminD.However, the lowlevels of sunlightduringwinterputthe UK populationatriskof vitaminDdeficiency,and since there are fewfoodsrichinvitaminD (oilyfishandeggyolkcontainsthe most),the vitaminD intake of anyone livinghere isoftenlow.Thisissue isincreasedwhensunscreenisusedheavily,or whenskiniscovereddue tothe cold,or religiousrequirements,asthe intake fromsunlightisfurther restricted(6).DeficiencyinvitaminDmostfamouslyleadstoricketsinchildren,andasimilardisease inadultscalledosteomalacia.There isalsoapositive associationof deficiencywithfracture risk,and otherpossible benefitsinclude areductioninthe riskof cancer,infections,autoimmune diseases, dementia,andevenautism(6).The efficacyof supplementsconcerningthisdeficiencyisdisputed, althoughsupplementationisrecommendedforpregnantorbreast-feedingwomen,andthose who have little exposure todirectsunlight(i.e.night-shiftworkers,office workers) (7).Ithastherefore beensuggestedthatfortifyingparticularfoodswithvitaminDwouldbenefitthiswidespreadissue, especially foodsrichincalcium,whichwouldimprove bothvitaminDandcalciumabsorptionfrom food,as done inthe USA. Milkis mandatorilyfortified,andbreakfastcereals,yogurtsandorange juice maybe fortifiedif the manufacturerwishesto inAmerica.Incomparison,some breakfast cereals,andsome margarinesare fortifiedwithvitaminD,andnone isaddedto milk inthe UK (8). Once again,many well-respectedauthorities suchasSACN have suggestedthatthe fortificationof foodswithvitaminDwouldbe extremelybeneficial, butthe governmenthas still chosentoignore thisadvice. Why fortificationprogrammeshave notbeenundertaken bythe UK governmentisbeyond comprehensiontothose whounderstandthe positive impactitwouldhave onanyone livinginthe UK. Disease isanissue thateveryone hascome intocontact withintheirlifetime,andmanyknow of the devastationthatitleavesbehind.Whythen,whenlivescouldbe saved,the qualityof those lives couldbe improved,andthe NHSwouldsave moneyontreatingthese conditions,isthisissue so blatantlydisregardedbythose whohave the powertomake changes? By Emma Steer, 2nd yearBSc Nutrition. References: (1) Novielli C,2014, RememberingGrayson:AnencephalicBabyFacebookBannedWhose Life ImpactedsoMany [online],date accessed[13/03/2016],URL [http://www.lifenews.com/2014/03/03/remembering-grayson-anencephalic-baby- facebook-banned-whose-life-impacted-so-many/] (2) Morris J.K,RankinJ,KurinczukJ.J,SpringettA,TuckerD, WellesleyD,WreyfordB,WaldN.J, 2015, Preventionof neural tube defectsin the UK:a missedopportunity,Archivesof Disease inChildhood[online],date accessed[13/03/2016],URL [http://adc.bmj.com/content/early/2015/11/13/archdischild-2015-309226.abstract] (3) FoodStandardsAgency,2016, Folicacid fortification [online],date accessed[13/03/2016], URL [https://www.food.gov.uk/northern-ireland/nutritionni/folic-acid] (4) BBC News,2015, Folicacidto fortifyflour'wouldcutbirthdefects' [online],date accessed [13/03/2016], URL [http://www.bbc.co.uk/news/health-35122699] (5) Centers forDisease Control andPrevention(USA),2015, Folicacidfortificationcontinuesto preventneural tube defect [online],date accessed[13/03/2016], URL [http://www.cdc.gov/ncbddd/folicacid/features/folicacid-prevents-ntds.html]
  • 3. (6) ButtrissJ.L,2015, VitaminD:Sunshine vs.dietvs.pills,NutritionBulletin(BritishNutrition Foundation) [online],volume 40,issue 4, pages279 – 285, date accessed[13/03/2016], URL [http://onlinelibrary.wiley.com/doi/10.1111/nbu.12172/pdf] (7) NHS Choices,2015, VitaminD[online],date accessed[13/03/2016], URL [http://www.nhs.uk/Conditions/vitamins-minerals/Pages/Vitamin-D.aspx#] (8) UnitedStatesDepartmentof HealthandHumanServics,2014, VitaminD[online],date accessed[13/03/2016], URL [https://ods.od.nih.gov/factsheets/VitaminD- HealthProfessional/#h4]