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LYMPHATIC
FILARIASIS
DR. MAHESWARI JAIKUMAR
NATIONAL FILARIA
CONTROL PROGRAMME
(NFCP) IN INDIA
• Filariasis is caused by several round,
coiled and thread-like parasitic
worms belonging to the family
filariea.These parasites after getting
deposited on skin penetrate on their
own or through the opening created
by mosquito bites to reach the
lymphatic system.
• The disease is caused by the
nematode worm,
either Wuchereria
bancrofti or Brugia malayi
• Is transmitted by ubiquitous
mosquitospeciesCulex quinquefasci
atus & Mansonia annulifera/M.uni
formis respectively.
• BRUGIAN FILARIASIS: Lymphadenitis
(swollen and painful lymphnode)
occurs episodically, most commonly
affecting one inguinal lymph node at a
time. The infection lasts for several
days and usually heals spontaneously.
The frequency of episodes may vary
from 1-2 attacks per year to several
attacks per month.
• Sometimes lymphadenitis is followed
by a characteristic retrograde
lymphangitis. The infection may
spread to the surrounding tissues,
and occasionally involves the whole
thigh or entire limb. The infected
lymph node may become an abscess,
ulcerate, and heal with fibrotic
scarring.
• The acute clinical course with its
complications may last from several
weeks to 3 months.
Characteristically, elephantiasis
involves the leg below the knee but
occasionally it affects the arm below
the elbow. Genital lesions or chyluria
(milky colour urine) do not occur in
brugian filariasis.
BANCROFTIAN FILARIASIS:
• The lymphatic vessels of the male
genitalia are most commonly affected in
bancroftian filariasis, producing episodic
funiculitis (inflammation of the spermatic
cord), epididymitis and orchitis.
• Adenolymphangitis of the extremities is
less common. Hydrocele is the most
common sign of chronic bancroftian
filariasis, followed by lymphoedema,
elephantiasis and chyluria.
LYMPHATIC FILARIASIS (LF)
• commonly known as elephantiasis is a
disfiguring and disabling disease, usually
acquired in childhood. In the early stages,
there are either no symptoms or non-
specific symptoms.
• Although there are no outward
symptoms, the lymphatic system is
damaged. This stage can last for several
years. Infected persons sustain the
transmission of the disease.
• Due to damaged lymphatic system,
patients with lymphoedema have
frequent attacks of infection causing
high fever and severe pain. Patients may
be bed-ridden for several days and
normal routine activities become
difficult.
• Such attacks not only cause acute
physical suffering but also directly
impede the earning capacity of the
individual.
FILARIA VECTORS
• C.quinquefasciatus is the vector
of W.bancrofti in the mainland.
• C.quinquefasciatus breeds in
association with human habitations
and is the domestic pest
mosquitoes, preferring polluted
waters, such as sewage and sullage
water collections including cess
pools, cess pits, drains and septic
tanks.
• The eggs are laid in rafts containing
150-40 eggs each depending on
quality and quantity of blood meal
taken.
• At the optimum temperature of 250
C to 300 C, the eggs hatch within 24
to 48 hours.
TRANSMISSION OF LYMPHATIC
FILARIASIS
•
The adult produces millions of very
small immature larvae known as
microfilariae, which circulate in the
peripheral blood with marked
nocturnal periodicity.
• The worms usually live and produce
microfilariae for 5-8 years.
ADULT FILARIAL WORMS
(MACROFILARIAE) INHABITING LYMP
HATIC SYSTEM OF MAN
• Lymphatic filariasis is transmitted through
mosquito bites.
•
The persons having circulating
microfilariae are outwardly healthy but
transmit the infection to others through
mosquitoes.
The persons with chronic filarial swellings
suffer severely from the disease but no
longer transmit the infection.
LIFE CYCLE OF FILARIA PARASITE
MAGNITUDE OF DISEASE
• Cases of filariasis have been recorded
from Andhra Pradesh, Assam, Bihar,
Chhattisgarh, Goa, Jharkhand,
Karnataka, Gujarat, Kerala, Madhya
Pradesh, Maharashtra, Orissa, Tamil
Nadu, Uttar Pradesh, West Bengal,
Pondicherry, Andaman & Nicobar
Islands, Daman & Diu, Dadra & Nagar
Haveli and Lakshadweep.
FILARIA ENDEMIC DISTRICTS
NATIONAL FILARIA
CONTROL PROGRAMME
(NFCP)
• After pilot project in Orissa from
1949 to 1954, the National Filaria
Control Programme (NFCP) was
launched in the country in 1955
with the objective of delimiting the
problem, to undertake control
measures in endemic areas and to
train personnel to man the
programme.
• The main control measures were
mass DEC administration, antilarval
measures in urban areas and indoor
residual spray in rural areas. The
NFCP set-up and population
protected are given in the table
below:
STRATEGY
• Recurrent anti-larval measures at
weekly intervals.
• Environmental methods including
source reduction by filling ditches,
pits, low lying areas, deweeding,
desilting, etc.
• Biological control of mosquito
breeding through larvivorous fish.
• Anti-parasitic measures through
'detection' and 'treatment' of
microfilaria carriers and disease
person with DEC by Filaria Clinics in
towns covered under the
programme.
REVISED STRATEGY
• Annual Mass Drug
Administration with single dose of
DEC was taken up as a pilot project
covering 41 million population in
1996-97 and extended to 74 million
population.
• This strategy was to be continued
for 5 years or more to the
population excluding children below
two years, pregnant women and
seriously ill persons in affected
areas to interrupt transmission of
disease.
MORBIDITY MANAGEMENT
• Home based management of
lymphoedema cases and
- up-scaling of hydrocele operations
in the identified CHCs / District
hospitals/ medical colleges.
NATIONAL GOAL
The National Health Policy 2002
aims at Elimination of Lymphatic
Filariasis by 2015.
STRATEGY FOR ELIMINCATION OF
LYMPHATIC FILARIASIS
• The strategy for achieving the goal of
elimination is by Annual Mass Drug
Administration of Anti Filarial Drugs
(DEC+Albendazole) for 5 years or more to
the population excluding children below
two years, pregnant women and seriously
ill persons in affected areas to interrupt
transmission of disease.
•
• Home based management of cases
who already have the disease and
hydrocelectomy operations in
identified CHCs and hospitals.
MDA - 2004
• Mass Drug Administration of single dose
of DEC was launched as National Filaria
Day (NFD) on 5th June 2004 by Dr. A.
Ramadoss, Hon'ble Union Minister for
Health & Family Welfare in Thane
district in Maharashtra . Smt. P. Lakshmi,
Hon'ble Union Minister of State for
Health & Family Welfare initiated the
MDA in Raibareilly district in Uttar
Pradesh.
FILARIASIS CONTROL PROGRAMME-INDIA
FILARIASIS CONTROL PROGRAMME-INDIA

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FILARIASIS CONTROL PROGRAMME-INDIA

  • 3. • Filariasis is caused by several round, coiled and thread-like parasitic worms belonging to the family filariea.These parasites after getting deposited on skin penetrate on their own or through the opening created by mosquito bites to reach the lymphatic system.
  • 4. • The disease is caused by the nematode worm, either Wuchereria bancrofti or Brugia malayi • Is transmitted by ubiquitous mosquitospeciesCulex quinquefasci atus & Mansonia annulifera/M.uni formis respectively.
  • 5. • BRUGIAN FILARIASIS: Lymphadenitis (swollen and painful lymphnode) occurs episodically, most commonly affecting one inguinal lymph node at a time. The infection lasts for several days and usually heals spontaneously. The frequency of episodes may vary from 1-2 attacks per year to several attacks per month.
  • 6. • Sometimes lymphadenitis is followed by a characteristic retrograde lymphangitis. The infection may spread to the surrounding tissues, and occasionally involves the whole thigh or entire limb. The infected lymph node may become an abscess, ulcerate, and heal with fibrotic scarring.
  • 7. • The acute clinical course with its complications may last from several weeks to 3 months. Characteristically, elephantiasis involves the leg below the knee but occasionally it affects the arm below the elbow. Genital lesions or chyluria (milky colour urine) do not occur in brugian filariasis.
  • 8. BANCROFTIAN FILARIASIS: • The lymphatic vessels of the male genitalia are most commonly affected in bancroftian filariasis, producing episodic funiculitis (inflammation of the spermatic cord), epididymitis and orchitis. • Adenolymphangitis of the extremities is less common. Hydrocele is the most common sign of chronic bancroftian filariasis, followed by lymphoedema, elephantiasis and chyluria.
  • 10. • commonly known as elephantiasis is a disfiguring and disabling disease, usually acquired in childhood. In the early stages, there are either no symptoms or non- specific symptoms. • Although there are no outward symptoms, the lymphatic system is damaged. This stage can last for several years. Infected persons sustain the transmission of the disease.
  • 11. • Due to damaged lymphatic system, patients with lymphoedema have frequent attacks of infection causing high fever and severe pain. Patients may be bed-ridden for several days and normal routine activities become difficult. • Such attacks not only cause acute physical suffering but also directly impede the earning capacity of the individual.
  • 13. • C.quinquefasciatus is the vector of W.bancrofti in the mainland. • C.quinquefasciatus breeds in association with human habitations and is the domestic pest mosquitoes, preferring polluted waters, such as sewage and sullage water collections including cess pools, cess pits, drains and septic tanks.
  • 14. • The eggs are laid in rafts containing 150-40 eggs each depending on quality and quantity of blood meal taken. • At the optimum temperature of 250 C to 300 C, the eggs hatch within 24 to 48 hours.
  • 15. TRANSMISSION OF LYMPHATIC FILARIASIS • The adult produces millions of very small immature larvae known as microfilariae, which circulate in the peripheral blood with marked nocturnal periodicity. • The worms usually live and produce microfilariae for 5-8 years.
  • 16. ADULT FILARIAL WORMS (MACROFILARIAE) INHABITING LYMP HATIC SYSTEM OF MAN
  • 17. • Lymphatic filariasis is transmitted through mosquito bites. • The persons having circulating microfilariae are outwardly healthy but transmit the infection to others through mosquitoes. The persons with chronic filarial swellings suffer severely from the disease but no longer transmit the infection.
  • 18. LIFE CYCLE OF FILARIA PARASITE
  • 19. MAGNITUDE OF DISEASE • Cases of filariasis have been recorded from Andhra Pradesh, Assam, Bihar, Chhattisgarh, Goa, Jharkhand, Karnataka, Gujarat, Kerala, Madhya Pradesh, Maharashtra, Orissa, Tamil Nadu, Uttar Pradesh, West Bengal, Pondicherry, Andaman & Nicobar Islands, Daman & Diu, Dadra & Nagar Haveli and Lakshadweep.
  • 22. • After pilot project in Orissa from 1949 to 1954, the National Filaria Control Programme (NFCP) was launched in the country in 1955 with the objective of delimiting the problem, to undertake control measures in endemic areas and to train personnel to man the programme.
  • 23. • The main control measures were mass DEC administration, antilarval measures in urban areas and indoor residual spray in rural areas. The NFCP set-up and population protected are given in the table below:
  • 24. STRATEGY • Recurrent anti-larval measures at weekly intervals. • Environmental methods including source reduction by filling ditches, pits, low lying areas, deweeding, desilting, etc.
  • 25. • Biological control of mosquito breeding through larvivorous fish. • Anti-parasitic measures through 'detection' and 'treatment' of microfilaria carriers and disease person with DEC by Filaria Clinics in towns covered under the programme.
  • 26. REVISED STRATEGY • Annual Mass Drug Administration with single dose of DEC was taken up as a pilot project covering 41 million population in 1996-97 and extended to 74 million population.
  • 27. • This strategy was to be continued for 5 years or more to the population excluding children below two years, pregnant women and seriously ill persons in affected areas to interrupt transmission of disease.
  • 28.
  • 30. • Home based management of lymphoedema cases and - up-scaling of hydrocele operations in the identified CHCs / District hospitals/ medical colleges.
  • 31. NATIONAL GOAL The National Health Policy 2002 aims at Elimination of Lymphatic Filariasis by 2015.
  • 32. STRATEGY FOR ELIMINCATION OF LYMPHATIC FILARIASIS • The strategy for achieving the goal of elimination is by Annual Mass Drug Administration of Anti Filarial Drugs (DEC+Albendazole) for 5 years or more to the population excluding children below two years, pregnant women and seriously ill persons in affected areas to interrupt transmission of disease. •
  • 33. • Home based management of cases who already have the disease and hydrocelectomy operations in identified CHCs and hospitals.
  • 34. MDA - 2004 • Mass Drug Administration of single dose of DEC was launched as National Filaria Day (NFD) on 5th June 2004 by Dr. A. Ramadoss, Hon'ble Union Minister for Health & Family Welfare in Thane district in Maharashtra . Smt. P. Lakshmi, Hon'ble Union Minister of State for Health & Family Welfare initiated the MDA in Raibareilly district in Uttar Pradesh.