The study evaluates the impact of human activities on air quality in Madurai, India, using Bayesian networks and Inverse Distance Weighting (IDW) interpolation techniques on data collected during the COVID-19 pandemic. It highlights how different levels of human intervention during lockdowns affect the Air Quality Index (AQI) across residential, commercial, and industrial locations. The findings reveal significant insights into the causal relationships between human activities and air quality variations, offering potential strategies for improving AQI levels in urban areas.