The Ethical dilemmas in precision medicine arise from balancing the potential benefits of tailored treatments with concerns about privacy, consent, equity, and the implications of genetic information. These Dilemmas include issues around informed consent for data sharing, ensuring equitable access to precision medicine technologies, and safeguarding against discrimination based on Information. The potential for misuse or unintended consequences further complicate the ethical landscape of precision medicine. The Precision medicine widely used in Data Integration, Biomarkers, Targeted Therapies, predictive modeling, Clinical Decision Support. Precision Medicine improves the Patient outcomes, enhancing treatment efficacy, and reducing healthcare costs by minimizing trial and error in treatment selection. The precision medicine also raises Ethical legal and social complications related to data privacy, consent and equitable access and the potential for Discrimination based on information.
Ethical Dilemmas in Precision Medicine: Navigating the Intersection of Science and Morality
1. Welcome
ETHICAL DILEMMAS IN PRECISION MEDICINE:
NAVIGATING THE INTERSECTION OF SCIENCE AND
MORALITY
Name : S Nikhil
Designation: Pharm-D
Student ID : 012/012024
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
1
2. Index
• Introduction
• Definition
• Ethical Dilemmas in precision Navigating Intersection of Science and
Morality
• Challenges in Implementation of Precision and medicine
• Preventive Measures
• Conclusions
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
2
3. Introduction
The Ethical dilemmas in precision medicine arise from balancing the potential benefits of tailored
treatments with concerns about privacy, consent, equity, and the implications of genetic
information. These Dilemmas include issues around informed consent for data sharing, ensuring
equitable access to precision medicine technologies, and safeguarding against discrimination
based on Information. The potential for misuse or unintended consequences further complicate
the ethical landscape of precision medicine. The Precision medicine widely used in Data
Integration, Biomarkers, Targeted Therapies, predictive modeling, Clinical Decision Support.
Precision Medicine improves the Patient outcomes, enhancing treatment efficacy, and reducing
healthcare costs by minimizing trial and error in treatment selection. The precision medicine also
raises Ethical legal and social complications related to data privacy, consent and equitable access
and the potential for Discrimination based on information.
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
3
4. Definition
Precision Medicine is also known as personalized Medicine, refers to ana oproach to medical
treatment and healthcare that makes into account individual variability in genes,
environment and lifestyle. It involves the customization of healthcare interventions, such as
prevention, diagnosis, and treatment, to the specific charecteristics of each patient. By
considering factors such as Biomarkers, Illness of patients to optimize therapeutic efficacy
minimize adverse affects and improve patient outcomes. By Leveraging advances in
Genomics, Data Analytics, and technology, precision medicine aims to deliever more
targeted and effective patient outcomes and reducing Healthcare costs.
Ethical dilemmas in precision medicine:
1. Informed Consent
2. Privacy And Security Data
3. Equity and Access
4. Commercialisation and Conflicts of Interest
5. Stigmatizsation and Discrimination
6 Benefits and harm
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
4
5. Ethical Dilemmas in Precision Medicine Navigating Intersection of Science and Morality:
• Informed Consent:
Balancing is need for informed consent with the complexity of the information and the potential for the unexpected
findings. Patients may struggle to understand the implications of genetic testing, including the possibility of identifying
variants with uncertain significance or incidental findings unrelated to the purpose of testing.
• Privacy and data security:
Safeguarding the privacy of health data in precision medicine, where large-scale genomic databases are
increasingly used for clinical research and clinical purposes. Ensuring adequate Data Protection measures
while facilitating data sharing for scientific discovery poses a challenge.
• Equity and Access:
Addressing the disparities in access to precision medicine technologies and therapies, which may
exacerabate existing inequalities in healthcare. High costs, Limited testing in certain populations, and
unequal distribution of resources for implementing precision medicine interventions.
• Commercialization and conflicts of interest:
Navigating the involvement of commercial entitiles in precision medicine research and development,
which may introduce conflicts of interest and influence decision- making processes. Balancing the pursuit
of profit with Ethical imperatives to prioritize the patient welfare and scientific integrity is essential.
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
5
6. Stigmatization and Discrimination:
• Mitigating the risk of stigmatization and discrimination based on
genetic information, including concerns about genetic
determinism and the potential for misuse of genetic data in
employment, insurance, and social contexts.
Benefits and Harm:
• In Assesing the balance between potential benefits and harms of
precision medicine Interventions, particularly in cases where the
Preditive power of genetic Information is Uncertain or Where
interventions may have unintended consequences.
• Navigating these Dilemmas requires the interdisciplinary collaboration
among healthcare providers, researchers, and patient to robust for
frame making works for decision making, prioritise patient interests,
uphold principles of justice and beneficence, and ensure
transparency and accountability in the implementation of precision
medicine Initiatives.
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
6
7. Implementation of Precision Medicine:
• Data intergration and Analysis:
Integrating diverse sources of data, including genomic, clinical, environmental, and
lifestyle information, and developing sophisticated Analytical methods to interpret complex
datasets effectively.
• Interoperability and Standardisation:
Ensuring compatibility and consistency of data formats, terminilogy and protocols across
different healthcare systems and research platforms to facilitate data sharing and
collaboration.
• Implementation of Science and Health Equity:
Conducting Research On implementation strategies, dissemination, and adoption of
precision medicine interventions in diverse healthcare settings, populations, and
communities to maximise their impact and address disparities in healthcare access and
outcomes.
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
7
8. Preventive Measures:
1. Transparency
2. Equitable Access
3. Regulatory Oversights
4. Data Privacy and Security
5. Continual Evaluation
6. Accountability
7. Ethical Guidelines
8. Community Engagement
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
8
9. • Conclusions:
Ensuring patients have the autonomy to make the informed situations about their healthcare
while also striving to maximise benefits and minimise harm through Precision medicine
interventions.
Establishing clear ethical guidelines and regulations for the collection,use, and sharing of
genetic and personal health data.
Acknowledging The evolving nature of precision medicine and its potential long-term societal,
ethical, economical implications, necessitating ongoing evaluation and adaptation of ethical
frameworks and guidelines.
Foster collaboration between healthcare Proffessionals, Researchers, Policy makers, and
patient advocacy groups to address the ethical challenges collectively.
By Integrating These approaches, stakeholders can work together to mitigate ethical
dilemmas and promote responsible and equitable use of precision medicine technologies
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
9
10. Thank You!
www.clinosol.com
(India | Canada)
9121151622/623/624
info@clinosol.com
10/18/2022
www.clinosol.com | follow us on social media
@clinosolresearch
10