Erectile dysfunction (ED) is the inability to develop or maintain an erection firm enough for sex. It can be caused by physical or psychological factors that impair blood flow or nerve signals to the penis. Common physical causes include atherosclerosis, diabetes, neurological conditions, and injuries or surgery to the penis, pelvis, or surrounding areas. Lifestyle factors like smoking, alcoholism, cycling for long periods, and sleep disorders can also contribute to ED. Treatment options include oral medications like avanafil, hormone therapy, pumps or implants, and counseling. Avanafil is a fast-acting PDE5 inhibitor used to treat ED with few side effects and a duration of up to 6 hours.