man with erectile dysfunction
Shutterstock
Erectile dysfunction (ED), or impotence, is a major challenge for many men today regardless of their age — young, middle-aged, or old. Because erectile dysfunction may be caused by many factors — a health condition, emotional or relationship problems, some kinds of medication, smoking, drugs, or alcohol — an erectile dysfunction cure is possible.
Though erectile dysfunction treatment options may include ED medication and surgery, there
Point out older men’s wilting erections, the ones immediately believe Viagra. Indeed, Viagra, Cialis, as well as Levitra, can increase flags which have fallen in order to half personnel. But less than half associated with men more than 50 possess tried all of them, and of these, fewer compared to half possess renewed their own prescriptions.
Sex differences in the relationships between body dissatisfaction, quality of...Scoti Riff
Background: Body dissatisfaction is associated with impairment in women's quality of life (QoL). To date, research has not examined the relationship between body dissatisfaction and men's QoL, or sex differences in this relationship.
Methods: A community sample of 966 males and 1,031 females living in Australia provided information about their body dissatisfaction, mental health and physical health-related QoL, and eating disorder symptoms. Data were analysed using three hierarchical multiple regressions and interactions between body dissatisfaction and sex were examined.
Results: For both sexes, increasing levels of body dissatisfaction were associated with poorer mental and physical health-related QoL and greater psychological distress. The adverse associations between body dissatisfaction and mental health-related QoL, and between body dissatisfaction and psychological distress, were more pronounced for males.
Conclusion: High levels of body dissatisfaction may threaten the psychological and physical wellbeing of both men and women. Body dissatisfaction appears to be a public health problem, distinct from the eating disorders and other adverse psychological phenomena for which body dissatisfaction is commonly discussed as a risk factor. Males, historically understudied and underrepresented in body image research, warrant increased empirical attention.
Point out older men’s wilting erections, the ones immediately believe Viagra. Indeed, Viagra, Cialis, as well as Levitra, can increase flags which have fallen in order to half personnel. But less than half associated with men more than 50 possess tried all of them, and of these, fewer compared to half possess renewed their own prescriptions.
Sex differences in the relationships between body dissatisfaction, quality of...Scoti Riff
Background: Body dissatisfaction is associated with impairment in women's quality of life (QoL). To date, research has not examined the relationship between body dissatisfaction and men's QoL, or sex differences in this relationship.
Methods: A community sample of 966 males and 1,031 females living in Australia provided information about their body dissatisfaction, mental health and physical health-related QoL, and eating disorder symptoms. Data were analysed using three hierarchical multiple regressions and interactions between body dissatisfaction and sex were examined.
Results: For both sexes, increasing levels of body dissatisfaction were associated with poorer mental and physical health-related QoL and greater psychological distress. The adverse associations between body dissatisfaction and mental health-related QoL, and between body dissatisfaction and psychological distress, were more pronounced for males.
Conclusion: High levels of body dissatisfaction may threaten the psychological and physical wellbeing of both men and women. Body dissatisfaction appears to be a public health problem, distinct from the eating disorders and other adverse psychological phenomena for which body dissatisfaction is commonly discussed as a risk factor. Males, historically understudied and underrepresented in body image research, warrant increased empirical attention.
Jake Mager
English 104
30 April 2012
This PowerPoint is about caffeine and how it is over all unhealthy. I used mainly questions in order to keep the audience interested. The slide with the question asking “Is drinking coffee or energy drinks worth the side effects?” has no picture in order for the audience to focus on that question and come up with their own conclusion that should align with the conclusion on the next slide. Some of the pictures I chose to use are a bit shocking but I felt as if that would support my case very well.
Distilling fact from fiction is an important part of my job as an evidence-based health writer. The Low T (low testosterone) story, originally assigned as a feature for an online health foundation, was intended to explore the facts vs. the frenzy of the low T debate. However, it quickly grew into so much more. While preparing for my interview with a key source, I was perplexed that the data did not line up with the conclusions drawn by a major, trusted health journal, nor many of the headlines in mainstream media stories. My analysis was correct and the story took on a whole different direction about egregious headlines, faulty conclusions and the journal's refusal to retract a study. There are four sections in this reporting package:
Low T: Separating Facts from Frenzy (feature story)
The Low T Story: Hunting for the Truth (blog)
Breaking: The Low T Story: Hunting for the Truth, Part 2 (blog)
JAMA Refuses to Retract Paper on Testosterone Risks (blog)
Natural treatment of erectile dysfunction with ayurvedic medicines (2)Ankit Khanna
Are you worried about the problem of Erectile Dysfunction? Follow this natural treatment of Erectile Dysfunction with Ayurvedic medicines that are effective.
A warm welcome to CREST.BD’s Bipolar Wellness Centre webinar series! These webinar slides provide a summary of current research evidence on the relationship between physical health, bipolar disorder (BD) and quality of life (QoL), as well as pointing you to some tools and resources to help you flourish in your physical life.
Weight loss formulas are all the rage, especially for busy people who want to start losing weight without having to go through an exercise routine or strict diet. Xenadrine is one such weight loss formula that promises quick weight loss. But how effective is Xenadrine, and is it safe?
Read more: http://dietopia.net/xenadrine.html#ixzz2RGeMk68G
Know the Home Remedies to cure Erectile Dysfunction to enjoy your sex life like Lifestyle changes, exercise, eat healthy food, stop smoking & alcohol consumption etc.
Jake Mager
English 104
30 April 2012
This PowerPoint is about caffeine and how it is over all unhealthy. I used mainly questions in order to keep the audience interested. The slide with the question asking “Is drinking coffee or energy drinks worth the side effects?” has no picture in order for the audience to focus on that question and come up with their own conclusion that should align with the conclusion on the next slide. Some of the pictures I chose to use are a bit shocking but I felt as if that would support my case very well.
Distilling fact from fiction is an important part of my job as an evidence-based health writer. The Low T (low testosterone) story, originally assigned as a feature for an online health foundation, was intended to explore the facts vs. the frenzy of the low T debate. However, it quickly grew into so much more. While preparing for my interview with a key source, I was perplexed that the data did not line up with the conclusions drawn by a major, trusted health journal, nor many of the headlines in mainstream media stories. My analysis was correct and the story took on a whole different direction about egregious headlines, faulty conclusions and the journal's refusal to retract a study. There are four sections in this reporting package:
Low T: Separating Facts from Frenzy (feature story)
The Low T Story: Hunting for the Truth (blog)
Breaking: The Low T Story: Hunting for the Truth, Part 2 (blog)
JAMA Refuses to Retract Paper on Testosterone Risks (blog)
Natural treatment of erectile dysfunction with ayurvedic medicines (2)Ankit Khanna
Are you worried about the problem of Erectile Dysfunction? Follow this natural treatment of Erectile Dysfunction with Ayurvedic medicines that are effective.
A warm welcome to CREST.BD’s Bipolar Wellness Centre webinar series! These webinar slides provide a summary of current research evidence on the relationship between physical health, bipolar disorder (BD) and quality of life (QoL), as well as pointing you to some tools and resources to help you flourish in your physical life.
Weight loss formulas are all the rage, especially for busy people who want to start losing weight without having to go through an exercise routine or strict diet. Xenadrine is one such weight loss formula that promises quick weight loss. But how effective is Xenadrine, and is it safe?
Read more: http://dietopia.net/xenadrine.html#ixzz2RGeMk68G
Know the Home Remedies to cure Erectile Dysfunction to enjoy your sex life like Lifestyle changes, exercise, eat healthy food, stop smoking & alcohol consumption etc.
Female More Female Libido/boosting libido in males larbi akamoum
Femin Plus is an effective product which stimulates the libido of women and has a general positive effect on the health of all women. In the composition of the product take into account high quality ingredients, which regulate hormonal activity.
Taking the product increases sexual appetite, guarantees greater vitality, reduces vaginal dryness and decreases mood swings during menstruation.
There's a lot of misinformation about the causes and treatments of erectile dysfunction (ED). To know the facts, you may need to bust some myths along the way. ED is a normal part of growing older and men have to learn to live with it. Although ED is more common among older men, that doesn't mean it's something you have to live with.
Lifestyle has a great influence on a person’s overall health and fertility is not an exception. An energetic routine, exercising, and yoga practicing can help to boost fertility. Exercising is helpful for increasing testosterone levels.
The unfortunate truth is that erectile dysfunction (ED) becomes more common as men get older. Generally, about 40% of men
in their 40s will have experienced difficulties achieving or maintaining an erection in the past.
Hormone Repacement Therapy (HRT) for men can be a life changing solution for men who are in their 40's, 50's and 60's and are experiencing low energy levels, low sex drive and have difficulties losing and keeping weight off.
Erectile Dysfunction Symptoms And TreatmentManas Das
This presentation describes Symptoms And Treatment of Erectile Dysfunction which is a very common diseases in men.Erectile Dysfunction can be cure easily if proper treatment will be taken.To identify Erectile Dysfunction some symptoms are there which can help you.
Bio Identical Hormone Replacement Therapy PresentationAzani Medical Spa
Dr. Monica Carezani Gavin, Diplomate of the American Academy of Anti-Aging Medicine, explains bio identical hormone replacement therapy (BHRT). BHRT as used by Suzanne Somers and Dr. Phil\'s wife and talked about by Oprah. Dr. Gavin provides BHRT through her medical practice Azani Medical Spa in Bethlehem Pa.
Similar to E.d. elixir: the natural erectile dysfunction fix (20)
Brain Training For Dogs - Unique Dog Training Courserdkumar3
Most Dog training programs today fail to engage your Dog on a mental level, and fail to develop his/her intelligence. With enough mental stimulation - many problem behaviors simply melt away. I'll explain why below.
Aim for a slow, steady weight loss by decreasing calorie intake while maintaining an adequate nutrient intake and increasing physical activity. You can cut calories without eating less nutritious food. The key is to eat foods that will fill you up without eating a large amount of calories. ! See more detail below (https://tinyurl.com/wkn697yw )
Plyometrics fitness adrenaline _ jump your way to a slimmer and fetter body inside this ebook you will discover the topics about adrenaline and it's impact on health adrenaline and weight loss association of slimming with other hormoner other than adrenaline nutrition fitnessand impact on slimming currant arear of interest in slimming 10 reasons why you should go for a fitter body and good health and it's arpect
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Health and fitness 101master your health wellness and fitness with this essential training guide inside this ebook
You will Discover the topics about analyze and change your life style into healthier one secret of health and fitness healthy nutrition and it's benefits stress management and you health exarcise and its
Types and tips for weaker and old age
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i-CAN-DO Model of Coaching
I use several models when coaching my clients but my favourite by far is the "I CAN DO" model. I like it not only because of its adaptability, it's a fairly basic model but is flexible enough to work with all areas of your life. More than this though, is the mnemonic itself, what better phrase then "I CAN DO"? Simply thinking that statement puts you in a positive frame of mind and reassures you that with a little bit of work you really can achieve whatever it is you put your mind to. This is a good frame of mind in which to start work on improving your life
Discover the Scientifically Proven Solution That Gets Your Baby to Sleep like Clockwork
Mary-Ann Schuler is a child psychologist and parenting expert with over 20 years of experience
She and her program Baby Sleep Miracle have been featured in publications such as “Parenting Magazine”, “Easy Parenting”, “Parents”
The outbreak of COVID-19 coronavirus and its impact on global mental health
Julio Torales, Marcelo O’Higgins, João Mauricio Castaldelli-Maia, Antonio Ventriglio
International Journal of Social Psychiatry, 0020764020915212, 2020
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondHealth Catalyst
Join us as we delve into the crucial realm of quality reporting for MSSP (Medicare Shared Savings Program) Accountable Care Organizations (ACOs).
In this session, we will explore how a robust quality management solution can empower your organization to meet regulatory requirements and improve processes for MIPS reporting and internal quality programs. Learn how our MeasureAble application enables compliance and fosters continuous improvement.
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...The Lifesciences Magazine
Deep Leg Vein Thrombosis occurs when a blood clot forms in one or more of the deep veins in the legs. These clots can impede blood flow, leading to severe complications.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
The Importance of Community Nursing Care.pdfAD Healthcare
NDIS and Community 24/7 Nursing Care is a specific type of support that may be provided under the NDIS for individuals with complex medical needs who require ongoing nursing care in a community setting, such as their home or a supported accommodation facility.
1. If ignored, erectile dysfunction can lead to complications, such as an
unsatisfactory sex life, low self-esteem, high anxiety, and relationship problems.
Getting a partner pregnant also becomes difficult if a man suffers with erectile
dysfunction.
A study published in May 2014 in The Journal of Sexual Medicine found that
some men can reverse erectile dysfunction with healthy lifestyle changes, such
as exercise, weight loss, a varied diet, and good sleep. The Australian
researchers also showed that even if erectile dysfunction medication is required,
it's likely to be more effective if you implement these healthy lifestyle changes.
For men searching for ED medication, there are many newer erectile dysfunction
treatments (all prescription drugs) that help you get an erection firm enough to
have sex, and most have few side effects.
Commonly prescribed erectile dysfunction treatments include:
Stendra (avanafil)
Viagra (sildenafil)
Cialis (tadalafil)
Levitra or Staxyn (vardenafil)
If you need erectile dysfunction treatment, talk with your doctor today.
1
Exercise Is an Active Erectile Dysfunction Treatment
a person running outside for exercise
Shutterstock
“There are many lifestyle changes that are erectile dysfunction remedies, but
among them, exercise is the ED treatment that can have the greatest impact,”
says Zachary R. Mucher, MD, a urologist in Sugar Land, Texas. “Exercise works
on several fronts to combat the development of ED and help reverse it once it
has become a problem.”
Exercise improves blood flow, which is vitally important to a strong erection, and
improves blood pressure by increasing nitric oxide in blood vessels, which he
says is exactly how Viagra works. Weight-bearing exercise can increase the
2. natural production of testosterone, a significant factor in erectile strength and sex
drive.
2
One Erectile Dysfunction Remedy Is a Healthy Diet
ingredients of a healthy diet for erectile dysfunction
Peter Reali/Corbi
The foods you eat can have a direct impact on erectile dysfunction, Dr. Mucher
says. A diet rich in fruit, veggies, whole grains, and fish, and with fewer servings
of red meat and refined grains, decreases the risk for ED.
A healthy diet also helps to maintain a healthy body weight, which is important
because men who have a 42-inch waist are 50 percent more likely to have ED
than men with a 32-inch waist. Also, obesity increases the risk for vascular
disease and diabetes, two factors that contribute to ED.
3
Sleep Is a Natural Erectile Dysfunction Treatment
a woman reaching for an alarm clock while in bed with her partner
Jamie Grill/Corbis
Poor sleep patterns can be a contributing factor for erectile dysfunction, Mucher
says. One review published in the journal Brain Research emphasized the
intricate relationship between the level of sex hormones like testosterone, sexual
function, and sleep, noting that testosterone levels increase with improved sleep,
and lower levels are associated with sexual dysfunction. Hormone secretion is
controlled by the body’s internal clock, and sleep patterns likely help the body
determine when to release certain hormones.
Adhering to a set sleep schedule is a natural erectile dysfunction remedy, and
can help ensure that those signals are clear and consistent.
4
Quit Smoking to Stop Erectile Dysfunction
a cigarette stubbed out in an ashtray, representing quitting smoking
Peter Dazeley/Getty Images
For many men, stopping smoking is an erectile dysfunction remedy, particularly
when ED is the result of vascular disease, which occurs when blood supply to the
3. penis becomes restricted because of blockage or narrowing of the arteries.
Smoking and even smokeless tobacco can also cause the narrowing of important
blood vessels and have the same negative impact.
If you smoke, talk to your doctor about quitting and whether prescription aids can
help you.
5
Limit Alcohol to Improve ED
an alcoholic drink in a glass
Thinkstock
“Alcohol is a depressant and can cause both temporary and long-term erectile
dysfunction,” Mucher cautions.
The central nervous system is responsible for releasing nitric oxide, an essential
chemical for producing and maintaining an erection, and heavy alcohol
consumption depresses the central nervous system, causing it to function less
efficiently. Not enough nitric oxide translates to erectile dysfunction.
6
Monitor Your Meds to End Erectile Dysfunction
a man holding medication and a glass of water
Corbis
Erectile dysfunction can occur as a side effect of medication taken for another
health condition. Common culprits are high blood pressure meds,
antidepressants, some diuretics, beta-blockers, heart medication, cholesterol
meds, antipsychotic drugs, hormone drugs, corticosteroids, chemotherapy, and
medication for male pattern baldness, among others.
If you think your medication might be causing ED, talk to your doctor, but don't
discontinue using it on your own. Some medication must be tapered off under a
doctor's supervision.
7
Acupuncture May Help With Erectile Dysfunction
a man receiving accupuncture for erectile dysfunction
Getty Images
4. Research is mixed on the effectiveness of acupuncture as an erectile dysfunction
cure, but one study published in November 2013 in the Journal of Alternative and
Complementary Medicine found that acupuncture can be beneficial for men
experiencing erectile dysfunction as a side effect of antidepressants, including
selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenaline
reuptake inhibitors (SNRIs).
Sexual side effects of these drugs happen to at least half of all people taking
them, and by some counts up to 90 percent.
8
Can Herbal Remedies Help or Hurt Erectile Dysfunction?
a pomegranate cut open, and pomegranate juice
Getty Images
“There are many herbal remedies that tout improvement in erectile function, but
most have little effect and may actually have detrimental side effects,” Mucher
says. Two natural erectile dysfunction treatments that have shown promise are
red ginseng and pomegranate juice.
“Ginseng is thought to increase nitric oxide production, leading to improved blood
flow," he says. "Pomegranate juice is a potent antioxidant and can help prevent
atherosclerosis." Always talk to your doctor before taking any supplements, as
they might interfere with other medication you're taking.
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THE LATEST IN ERECTILE DYSFUNCTION
Pornography Habit Is Linked to Erectile Dysfunction, Research Suggests
Survey says more then 50 percent with erectile dysfunction problems during
partnered sex don’t have a problem when watching porn.
5. By Beth Levine
July 22, 2020
Pfizer Launches Generic Viagra
The little blue pill is about to become a lot more affordable.
By Julie Marks
December 28, 2017
Generic Viagra: What Does It Mean for You?
The little blue pill is expected to go generic in December 2017.
By Julie Marks
December 1, 2017
How Aging Can Make Men Better in Bed (Really)
Aging and ED can slow men's sexual health, but pleasure is not only possible, it
can also improve quality of life in men 60 and older.
By Denise Mann
March 13, 2014
Erection Problems? This Habit May Be Why
Watching porn may extinguish erections in the bedroom. But the brain, not the
penis, is the problem.
By Denise Mann
February 4, 2014
What Happens When You Use Viagra But Don't Have ED
Viagra and other ED drugs are increasingly being misused and even abused.
Learn about the risks of recreational ED drug use.
By Chris Iliades, MD
January 30, 2014
Sexy Men Do Kegels
6. This sneaky, do-anywhere exercise can boost erections, banish leaks.
By Madeline R. Vann, MPH
January 21, 2014
How Women Can Deal With Erectile Dysfunction
Dealing with erectile dysfunction can be awkward and embarrassing, but you can
play an important role in encouraging the man in your life to get checked...
By Kristen Stewart
December 2, 2013
ED and the Sexless Relationship
Erectile dysfunction can lead to relationship problems. Learn why sex is
important in a relationship and for good health and how to restart your sex life...
By Kristen Stewart
November 15, 2013
Ask a Castle Connolly Top Doctor: How Often Are Vasectomy Reversals
Successful and Why?
A renowned urologist and top vasectomy reversal expert, recognized as a Castle
Connolly Top Doctor, discusses what factors influence the success of a ...
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8. Clinically known aetiologies of ED include organic, psychogenic and combined
origins.1 Cardiovascular disorders and diabetes mellitus are known to contribute
significantly to erectile dysfunction of organic origin.6,8 Organic causes of
erectile dysfunction are found in 80–90% of ED patients, and these include
vasculogenic (ie, arterial, cavernosal and mixed), neurogenic, anatomical and
endocrine causes.4 Psychogenic forms of ED are usually due to sexual
performance anxiety, depression and inhibited sexual drive.4
Recent studies have shown that vascular endothelial dysfunction is a major
cause of ED, suggesting that ED might be an early manifestation of
cardiovascular disease.2,9,10 Indeed, patients with ED possess many of the risk
factors associated with coronary artery disease (CAD), such as smoking,
hypertension, diabetes and hyperlipidaemia.1,10 The association between ED
and CAD has, therefore, raised concerns regarding the cardiovascular safety of
PDE-5 inhibitors.10
Allopathic medicines for erectile dysfunction
Three synthetic drugs, namely sildenafil citrate (Viagra™), tadalafil (Cialis™) and
vardenafil hydrochloride (Levitra™) are currently available on the pharmaceutical
market for the treatment of ED. As a class, these compounds are mild vasoactive
drugs and they act by selectively inhibiting the enzyme phosphodiesterase type-5
(PDE-5). PDE-5 catalyses the breakdown of the smooth muscle-relaxing agent,
cyclic guanosine monophosphate (cGMP), a second messenger of nitric oxide.10
In the body, inhibition of PDE-5 increases cGMP levels, reduces intracellular
calcium (Ca2+) and induces vasodilation.10,11 The drugs possess identical
mechanisms of action, but differ essentially in their duration of action and in some
aspects of their pharmacokinetic profiles. Recent clinical studies have shown that
the three PDE-5 inhibitors are effective and relatively safe, and that they do not
increase cardiovascular risk in patients with CAD.12-14
The availability of these PDE-5 inhibitors has provided effective and
well-tolerated oral treatments for ED.5,7,15,16 Moreover, these drugs have been
reported to improve endothelial function, 10,14 and are speculated to have
vascular and myocardial protective properties.10,17 As a class, the three drugs
are indicated for the treatment of erectile dysfunction only. They are
contra-indicated in patients undergoing therapy with any form of nitrate, either
9. regularly or intermittently. The common side effects of the three PDE-5 inhibitors
include headache and dyspepsia, back pain, myalgia and non-arteritic anterior
ischaemic optic neuropathy.
Synthetic phosphodiesterase-5 inhibitors
Sildenafil citrate (Viagra™) and related sexual stimulant ‘love’ drugs have been
widely studied for their tolerability, safety and efficacy in the treatment of erectile
dysfunction in a variety of patient populations. In men, oral sildenafil citrate,
tadalafil and vardenafil hydrochloride are generally known to be effective in
erectile dysfunctions of organic, psychogenic or mixed origins. However, the
aetiology of erectile dysfunction has been shown to have a significant impact on
treatment success and satisfaction rates, with neurogenic causes of erectile
dysfunction (eg, diabetes mellitus and prostate surgery) having significantly lower
treatment success rates than psychogenic or vasculogenic erectile
dysfunction.15
The pharmacokinetic characteristics of tadalafil differ significantly from those of
sildenafil citrate and vardenafil hydrochloride. The mean half-life for both
sildenafil and vardenafil is about four hours, whereas the mean half-life of
tadalafil is 17½ hours, and tadalafil has also been shown to improve erectile
dysfunction for up to 36 hours post dosing.12,16
African traditional remedies for erectile dysfunction
In Africa, from ancient times, plants have served as a dependable and
ever-ready source of medicines for the treatment of a plethora of chronic and
acute diseases of mankind. The various communities and societies on the
continent, in addition to ‘owning’ traditional remedies for ailments such as
hypertension, diabetes mellitus, arthritis and other chronic conditions, also ‘own’
remedies for socio-cultural diseases such as erectile dysfunction.
Thousands of African medicinal plants (belonging to several genera and families,
and with diverse chemical constituents) have been reported to possess
aphrodisiac and sexual stimulant properties (Koloko, pers commun). Each
African country has a catalogue of locally made, plant-derived sexual stimulants
under various local trade names such as Impotex™, TigerPower™,
SuperLove™, uBangalala™ and Burantashi™. Hundreds of such traditional,
plant-derived remedies are used in African countries for the effective treatment of
10. ED. For example, the Zulu people of South Africa have, for centuries, used the
roots of Eriosema species as a remedy for the treatment of erectile dysfunction
and/or impotence.
Generally, the genus Eriosema contains plants which fall under the Zulu
indigenous umbrella name of uBangalala, and most of the plant species listed
under this name are used mainly for the purpose of curing or alleviating
impotence..18,19 Hot milk infusions of Eriosema roots and/or pounded boiled
root decoctions of the plant are taken in small doses in the morning and at night
for impotence.18,19 As with oral Viagra™ taken with a fatty meal, oral
administration of an infusion or decoction of Eriosema roots with milk probably
delays or reduces the rate of absorption of the bioactive compounds from the
patient’s gastrointestinal tract, and thereby prolongs the duration of action of the
compounds in the body.
It has been suggested that for maximum benefit, milk infusions and decoctions of
Eriosema kraussianum roots are to be taken two to four hours before any
anticipated sexual intercourse, and the effects (achievement and maintenance of
penile erection sufficient for satisfactory sexual intercourse after penetration) of
the plant extracts have been reported to last for four to six hours following oral
dosing of the milk infusion or decoction of the rootstock extracts (Drewes, pers
commun). Unlike Viagra™, however, the bioavailability, half-life, Tmax, Cmax and
other pharmacokinetic parameters of the bioactive compounds of E kraussianum
are obscure at present. The effects of the extract on the biochemical activities of
cGMP and PDE-5 are also unknown.
Due to economic constraints, providing adequate modern medical care to all the
people in developing, third-world African countries is an elusive dream at
present. Therefore, for the treatment of erectile dysfunction in the rural,
peri-urban and some urban communities of Africa, it is prudent to look for
salvation in herbal medicines and plant-derived products.
Recent studies in our laboratories20-22 have shown that E kraussianum NE Br
(Fabaceae) is one of the promising plant species of South Africa with potential for
use as an effective remedy in the treatment of impotence and/or ED. Drewes et
al.20,21 have shown, in a rabbit experimental model, the plausible therapeutic
beneficial effects of bioactive compounds of E kraussianum in the management
11. of erectile dysfunction. The psycho-social benefits of using such plant-derived
crude remedies in rural African communities cannot be overemphasised. Since
men with ED of organic, psychogenic and mixed aetiologies are known to benefit
from Viagra™ therapy, it is speculated that E kraussianum extractives may also
be used effectively as a Viagra™ substitute in South African men with such
erectile dysfunction.
Conclusion
There is a dire need to develop some of the existing potent, African traditional
remedies for erectile dysfunction into scientifically acceptable natural medicines.
With the financial and goodwill support of governments, non-governmental
organisations and philanthropic individuals, coupled with the cooperation of
multinational pharmaceutical companies such as Pfizer and others, it should be
possible to develop some of the currently available African traditional remedies
for ED into acceptable, potent natural medicines in the foreseeable future. Such
existing remedies should be subjected to rigorous scientific scrutiny
experimentally (in laboratory animals) and clinically (in humans), in order to
establish their safety, efficacy, quality, mechanisms of action, side effects, and
possibly also, their contra-indications.
The goals of medicines, whether allopathic, traditional or complementary, are the
same, namely, to benefit patients therapeutically and improve their quality of life.
Based on these assumptions, one can look forward to a near future of integrated
orthodox and traditional medicines, and hope that experimental and clinical
research in traditional, complementary and alternative medicines will help to
develop affordable, safe and effective natural medicines for erectile dysfunction,
rather than criticising and marginalising unorthodox medicines, ethnomedical
claims and traditional findings.
With traditional health practitioners, pharmacists, orthodox medical practitioners,
nurses, botanists, chemists, pharmacologists, toxicologists and other scientists
working together collaboratively for a common purpose, the future of scientifically
developed, affordable, safe and effective natural medicines for ED will certainly
be in sight. Now is the time to ensure that future availability of scientifically
formulated, safe and effective traditional medicines for the treatment of erectile
dysfunction is not an elusive dream, but an imminent reality.
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