Capitalism is a system that operates according to the principle of entropy because it presents the universal tendency to evolve into a growing disorder and self-destruction. This situation is evidenced by the downward trend of the profit rate of the United States, largest world economy which was 24% in 1950 and 13% in 2000 and reach a rate of profit equal to zero in 2059, as well as the fall in the rate of profit at historical cost of the fixed capital of US corporations which was 32% in 1947 and 13% in 2007 and will reach zero in 2048. It follows, therefore, that the world capitalist system would become infeasible made impossible between 2048 and 2059 because profit rates will be negative from the mid-twenty-first century. Neoliberalism by denying the regulation of the world capitalist system collaborates on bringing the system to self-destruction.