Bowel cancer screening involves several tests to detect cancer early, including fecal occult blood tests, colonoscopy, and sigmoidoscopy. Risk factors for bowel cancer include family history, inflammatory bowel disease, polyps, red meat consumption, obesity, alcohol, and smoking. People are categorized into different risk groups based on family history and age of relatives' diagnoses. Screening recommendations vary depending on a person's level of risk. Complications of colonoscopy can include issues from bowel preparation or sedation, as well as infection or perforation during the procedure.

1. Bowel Cancer ScreeningBy: Pubudu Jayaweera

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Risk Factors
inherited genetic risk and
family history
inflammatory bowel disease
polyps
high red meat consumption, espec
processed meats
being overweight or obese
high alcohol consumption
smoking.

3. Screening tests
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• Fecal occult blood test
• specific faecal immunochemical test
• Colonoscopy
• Flexible sigmoidoscopy
• Flexible Sigmoidoscopy plus double-contrast barium enema
• computed tomography (CT) colonography
• genetic screening test
• Suitable for all categories business and personal presentation, eaque ipsa quae ab illo
inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo.

4. Risk Catogarisation
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•side of family
•family history
•age at diagnosis
•the number of relatives
affected by CRC
causes
sporadic familial Lynch FAP

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C0mplications of Colonoscopy
• bowel cleanout -
dehydration , Electrolytes
imbalance
• Sedation during the
procedure – Drug
reactions , Aspiration ,
Ischemia
• the procedure itself-
infection , perforation

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Lynch syndrome-related cancers include colorectal, small
bowel, endometrial, ovarian, gastric, brain and urothelial
cancers
Patients with 10–100 adenomas have an attenuated form
of FAP, which can be due to APC mutation (dominantly
inherited) or MUTYH bi-allelic mutations (recessive

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Risk Catogaries

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$7M

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How to Screen each group
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• Aspirin at 600 mg/day reduced Lynch
syndrome cancer incidence by 50–
68% in the Colorectal
Adenoma/Carcinoma Prevention
Programme 2 (CAPP2) trial.
• The National Bowel Cancer Screening
Program, using a faecal
immunochemical test, is being
expanded and by 2020 will offer
biennial screening for people aged 50-
74. GPs are critical, not just in
maximising participation, but
managing participants with a positive
FOBT
• faecal occult blood test (FOBT) can
reduce colorectal cancer (CRC)
mortality by 16%
Updates

11. Thank You for your time!