The document discusses several issues related to intellectual property rights (IPR) and drug patents. It notes that the recent drug price gouging scandal in the US provides an opportunity for countries like India to push for more flexible drug patent rules at the upcoming G20 summit. While drug companies drive innovation, the current system in countries like the US allows for excessive price increases even on older drugs. The document advocates for approaches that balance the needs of patients and drug companies to encourage continued innovation.
GlaxoSmithKline settled $20M with the SEC for bribery offenses. They’ve been charged with working with subsidiaries that paid bribes to foreign officials in China to increase sales in the region. To avoid similar fines, you may email me at: christel.boutros@tr.com to know more about Know Your 3rd Party Risk proposition and how Thomson Reuters Risk solutions can help.
Transitioning a medicine from prescription-only to over-the-counter status is big business—and the Emerging Markets hold the key to sustained growth for OTC marketers. But manufacturers looking at such opportunities for growth have number of questions in mind. This article clarifies many such issues and challenges of the stakeholders and typical segments to encash on.
for more information log on to www.interlinkconsultancy.com
GlaxoSmithKline settled $20M with the SEC for bribery offenses. They’ve been charged with working with subsidiaries that paid bribes to foreign officials in China to increase sales in the region. To avoid similar fines, you may email me at: christel.boutros@tr.com to know more about Know Your 3rd Party Risk proposition and how Thomson Reuters Risk solutions can help.
Transitioning a medicine from prescription-only to over-the-counter status is big business—and the Emerging Markets hold the key to sustained growth for OTC marketers. But manufacturers looking at such opportunities for growth have number of questions in mind. This article clarifies many such issues and challenges of the stakeholders and typical segments to encash on.
for more information log on to www.interlinkconsultancy.com
Is the Modi Govt Aware of the Damage being Inflicted on Modern Healthcare?Anup Soans
In a brilliant editorial, Dr. Sumit Ghosal lays bare the terrible damage being done to modern medicine through policies and actions that will push India backwards. while developed nations will experience the unprecedented benefits of modern healthcare.
This document brings together a set
of latest data points and publicly
available information relevant for
Healthcare Industry. We are very
excited to share this content and
believe that readers will benefit from
this periodic publication immensely.
“SWOT ANALYSIS OF NEW PHARMACEUTICAL COMPANY”Dharmik Bhatt
Main Objective
To find the Strength, weakness, Opportunities and threat of the company and all new pharmaceutical companies.
To find out the perception and expectation of doctors and retailers towards the new pharmaceutical company.
Sub Objectives
To find out the big player of the market (Tough Competitor).
To find the way for new pharmaceutical company from tough competition.
To create strategy for company with the help of research detail.
To analyze Vadodara market for company.
To create good communication bridge between new company to doctors and retailers, that full feel all require expectation of both.
This PPT contains complete analysis of Pharmaceutical Industry including worldwide and nationwide picture, leading organizations, SWOT analysis, Government policies and regulations, challenges and solutions.
22% компаний по данным Superjob работает в режиме home-офиса. Такой формат работы дает массу новых возможностей, но сокращает возможности контроля сотрудников. Как увеличить эффективность работы в таких условиях?
Is the Modi Govt Aware of the Damage being Inflicted on Modern Healthcare?Anup Soans
In a brilliant editorial, Dr. Sumit Ghosal lays bare the terrible damage being done to modern medicine through policies and actions that will push India backwards. while developed nations will experience the unprecedented benefits of modern healthcare.
This document brings together a set
of latest data points and publicly
available information relevant for
Healthcare Industry. We are very
excited to share this content and
believe that readers will benefit from
this periodic publication immensely.
“SWOT ANALYSIS OF NEW PHARMACEUTICAL COMPANY”Dharmik Bhatt
Main Objective
To find the Strength, weakness, Opportunities and threat of the company and all new pharmaceutical companies.
To find out the perception and expectation of doctors and retailers towards the new pharmaceutical company.
Sub Objectives
To find out the big player of the market (Tough Competitor).
To find the way for new pharmaceutical company from tough competition.
To create strategy for company with the help of research detail.
To analyze Vadodara market for company.
To create good communication bridge between new company to doctors and retailers, that full feel all require expectation of both.
This PPT contains complete analysis of Pharmaceutical Industry including worldwide and nationwide picture, leading organizations, SWOT analysis, Government policies and regulations, challenges and solutions.
22% компаний по данным Superjob работает в режиме home-офиса. Такой формат работы дает массу новых возможностей, но сокращает возможности контроля сотрудников. Как увеличить эффективность работы в таких условиях?
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Pharmaceutical Fraud: Health 2.0 Conference Highlights Scams Health 2Conf
This presentation by Health 2.0 Conference talks about pharmaceutical fraud and what are some of the most common spam perpetrated by scammers. This presentation also highlights how AI can help mitigate the effects of fraud better than any traditional method.
NAPM is a Section 21 Trade Association which was established in 1977. It is a voluntary, non-profit organisation consisting of South African and Generics based Pharmaceutical manufacturers and distributors. NAPM has a diverse membership comprising of 24 companies. Some of the NAPM’s function is to ensure that the sector plays a constructive role in our country’s economic growth, development and transformation and thereby create an environment in which the sector can thrive, expand, be competitive and enhance access of medicines to all of our country’s citizens.
Healthcare Industry is considered a defensive industry for investing. It consist of pharmaceuticals, medical device, bio technology and insurance segment.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. Don't Say No to Drugs
G20 should consider a new, more fair intellectual property rights regime
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2. Contd..
Cynics say that G20 meetings are a complete waste of time. The G20
was created for a coordinated fiscal and monetary push out of the
Great Recession of 2008-10. Since then, it seems to have lost its
rationale. Arvind Panagariya, India's Sherpa for the next G20 summit,
seeks new ideas that India can take up at the next G20 summit. I think
the recent drug scandal in the US is an excellent opportunity to launch
a long-term campaign to gradually change the US emphasis on tough
drug patents, and shift towards the softer patents desired by countries
like India. The US aims through its new trans-Pacific and trans-Atlantic
trade deals to make tough patents a fait accompli in all the countries
that dominate the world economy minus the Brics.
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3. Contd..
Drug Lords, Only Legal
The key feature of the new trade pacts is not lower tariffs -these are already
very low -but tighter standards on intellectual property rights (IPR) and the
environment. How can India challenge this? The G20 summit gives India -as
well as Brazil, China and other low-cost drug producers -a chance to highlight
recent US abuses of a tough patent regime.
American drug companies have broad public support -with some exceptions
-for stringent patent rules that allow companies unlimited pricing power for
new drugs.
This is seen as a just reward for life-saving innovations that are ex pensive to
bring to the market, and should be encouraged by a limited monopoly -that's
what a patent is and no price limits.
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4. Contd..
But the US public was absolutely scandalised last week by the cynical price
strategy of Martin Shkreli of Turing Pharmaceuticals. He raised the price of
Daraprim, used for a parasitic infection called toxoplasmo sis, by a whopping
4,000% overnight.
Why? Because he could, he sneered, and needed no further justification.
Shkreli has done no R&D to merit such an increase. His company pur chased
the drug rights after realising there were no competing producers for this
drug: it was off patent and had limited specialised uses. So, it had become a
natural monopoly .
This enabled him to raise prices sky high. Shkreli's unrepentant cynicism
stoked US public indignation, and induced the media to investigate price
gouging further. They uncovered many other examples.
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5. Contd..
URL Pharma got exclusive marketing rights for Colchicine, an ancient home remedy
for gout, and raised the price per tablet from 9 cents to $4.85, an increase of over
5,000%. Another old drug, tetracycline, is off patent. But branded tetracycline is
suddenly selling for $11 a pill, against 5 cents as recently as 2013. Clomipramine, an
antidepressant used in the 1960s, cost just 22 cents per pill in 2012. But today ,
some branded pills cost $8.17, an increase of 3,600%.
The examples are striking because they show companies' power to raise prices
even for off-patent drugs. Clearly , the scope is even higher for patented drugs. The
fact is that free markets do not function in medicines. Patients do not exercise free
choice or show price-resistance to goug ing, as happens in normal products. When
a patient in the US is ill, the doctor prescribes medicines without considering the
cost of cheaper alternatives that are almost as good, and is influenced more by the
marketing ploys -and sometimes even bribes -of drug companies. US companies
typically spend more on marketing than R&D.
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6. Contd..
Big medical bills are mostly paid by US insurance firms, which recoup the rising cost
through higher insurance premia for patients. So, the system eviscerates price
resistance and rewards gouging. The US media are now exposing this in a big way .
A Diseased Model
Indian activists gleefully claim that this vindicates their anti-patents campaign, and
for “putting people before corporations“. Alas, this is seductive but bogus rhetoric.
The world urgently needs new drugs. Many old diseases, including malaria and
tuberculosis, are making a comeback. No effective drugs exist for some tropical
diseases, and corporations do not innovate remedies because these look
unprofitable. Purchasing power in tropical countries is low, and price controls can
be high.
Germs of all sorts are becoming resistant to existing drugs. New drug discovery has
become very slow, and so, diseases are gaining ground. Sim ply abolishing patents,
or weakening IPR norms, will further slow drug de velopment, increasing sickness
and deaths by millions.
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7. Contd..
The need of the hour is to accelerate new drug disco very . Drug companies
can be price gougers. But they are also lifesavers.
So, we definitely need IPR rules that induce innovation, while check ing price
gouging. Price control and compulsory licensing are two such techniques, but
should be used care fully to create a fair patient-corpo ration balance, and
not become a populist way of making drug discov ery unprofitable.
Former British prime minister Gordon Brown suggested diverting foreign aid
to a fund that would pay large lump sums upfront to drug co mpanies for
new drugs to combat tro pical diseases, making such discov ery profitable.
We need constructive new approaches that treat patients and companies as
allies, not foes.
This requires new attitudes from not just the US, but from India and China
too, and will take time. The G20 is suited for long-term tasks.
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8. This platform has been started by Parveen Kumar Chadha with
the vision that nobody should suffer the way he has suffered
because of lack and improper healthcare facilities in India. We
need lots of funds manpower etc. to make this vision a reality
please contact us. Join us as a member for a noble cause.
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9. Our views have increased
the mark of the 2,00,000
Thank you viewers
Looking forward for franchise, collaboration,
partners.
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10. Contact us:- 011-25464531, 9818569476
E-mail:- nursingcrusade@gmail.com
We are also available on
Justdial New Delhi.
Nursing Crusade Earlier Known as
Nursing Hi Nursing
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