This report summarizes a meta-analysis and literature review on online learning. The meta-analysis included 99 studies comparing online and face-to-face learning. It found that, on average, students in online learning conditions performed modestly better than those receiving face-to-face instruction. However, online conditions varied significantly in terms of how learning activities were designed. A narrative review examined studies comparing variants of online learning, finding blended models combining online and face-to-face outperformed purely online models. Factors like incorporating media elements, active learning experiences, computer-based instruction, and supports for reflection impacted online learning outcomes. The report concludes that online learning shows promise but more research is needed on best practices.