This document discusses why research into intellectual and developmental disabilities takes a long time. It provides the example of research into Fragile X syndrome, which took over 70 years to fully understand the genetic cause and develop diagnostic techniques and treatments. The process involved many researchers making incremental discoveries over decades. Unexpected discoveries emerged along the way, such as how some "unaffected" males were at risk for other conditions. Effective interventions are still being sought. The document emphasizes that research is a collaborative, cumulative process that requires continued funding and support. It highlights some of the top scientists at the Vanderbilt Kennedy Center who conduct this important research.
THIS PRESENTATION IS ABOUT AUTISM, ITS NOSOLOGY, NEUROBIOLOGY, CLINICAL FEATURES AND MANAGEMENT.
CLINICAL FEATURES- Persistent deficits in social communications and social interaction across multiple contexts, Restricted, repetitive patterns of behaviour, interests and activities
SPECIFIERS- ASD without disorder of Intellectual development (ID) and with mild or no impairment of functional language, ASD with disorder of ID and with mild or no impairment of functional language, ASD without disorder of ID and with impaired functional language, ASD without disorder of ID and with absence of functional language, ASD with disorder of ID and with absence of functional language
This document provides health supervision guidelines for pediatricians caring for children with Down syndrome. It covers topics from prenatal visits through adolescence. Key points include:
- Discussing prenatal testing results and prognosis with expectant parents.
- Evaluating newborns for common conditions like heart defects, hearing loss, vision issues.
- Providing anticipatory guidance on development, supportive services, and recurrence risks.
- Performing regular screening exams in infancy and childhood for growth, thyroid function, hearing, vision and more.
- Addressing psychosocial needs of parents and siblings through counseling and support groups.
The guidelines aim to help children with Down syndrome achieve their full potential through
This document provides an overview of autism spectrum disorder (ASD). It discusses the epidemiology, etiology, classification, course, prognosis, and treatment of ASD. Some key points include:
- ASD is a neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors.
- The prevalence of ASD is approximately 1 in 160 children worldwide. Boys are diagnosed with ASD 4 times more often than girls.
- The causes of ASD are complex and not fully understood but likely involve both genetic and environmental factors.
- Treatment aims to reduce disruptive behaviors and promote skills in areas like language, communication, and self-care. Educational, pharmacological, and psychosocial approaches
Genetic counseling is a process that employs scientific knowledge of genetics and communication skills to help individuals understand genetic diagnoses and their implications. It involves gathering a family history, educating about genetic conditions and testing, and counseling to promote informed decision making. The goal is to address concerns relating to hereditary disorders and support adaptation to genetic risks or conditions.
The document discusses the diagnosis and conceptualization of ADHD from multiple perspectives. It notes that ADHD symptoms may represent an adaptive problem rather than a disorder, given evidence of genetic roots and neural plasticity. While diagnosis is important for communication and treatment, the classifications are temporary and shaped by current understanding, which continues to evolve with scientific advances.
This document provides an overview of genetic counseling. It defines genetics and genetic counseling, lists their objectives and components. It describes pedigree charting and the roles of the genetic counselor in providing information, estimating risk, and transmitting information to clients. Examples are given of different inheritance patterns and genetic disorders. The role of nurses in genetic counseling is outlined as receiving clients, obtaining family histories, providing support and information, encouraging questions, and maintaining privacy.
This document summarizes key aspects of child development from a biological perspective. It discusses the interplay between nature and nurture, including evidence from twin, adoption and feral studies. Genetic foundations are explored, including chromosomes, DNA, genes and inheritance. Common genetic conditions are described. The document also notes reproductive challenges and choices such as diagnostic tests, infertility treatments and adoption. Key frameworks for understanding genetic influences on development are presented.
THIS PRESENTATION IS ABOUT AUTISM, ITS NOSOLOGY, NEUROBIOLOGY, CLINICAL FEATURES AND MANAGEMENT.
CLINICAL FEATURES- Persistent deficits in social communications and social interaction across multiple contexts, Restricted, repetitive patterns of behaviour, interests and activities
SPECIFIERS- ASD without disorder of Intellectual development (ID) and with mild or no impairment of functional language, ASD with disorder of ID and with mild or no impairment of functional language, ASD without disorder of ID and with impaired functional language, ASD without disorder of ID and with absence of functional language, ASD with disorder of ID and with absence of functional language
This document provides health supervision guidelines for pediatricians caring for children with Down syndrome. It covers topics from prenatal visits through adolescence. Key points include:
- Discussing prenatal testing results and prognosis with expectant parents.
- Evaluating newborns for common conditions like heart defects, hearing loss, vision issues.
- Providing anticipatory guidance on development, supportive services, and recurrence risks.
- Performing regular screening exams in infancy and childhood for growth, thyroid function, hearing, vision and more.
- Addressing psychosocial needs of parents and siblings through counseling and support groups.
The guidelines aim to help children with Down syndrome achieve their full potential through
This document provides an overview of autism spectrum disorder (ASD). It discusses the epidemiology, etiology, classification, course, prognosis, and treatment of ASD. Some key points include:
- ASD is a neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors.
- The prevalence of ASD is approximately 1 in 160 children worldwide. Boys are diagnosed with ASD 4 times more often than girls.
- The causes of ASD are complex and not fully understood but likely involve both genetic and environmental factors.
- Treatment aims to reduce disruptive behaviors and promote skills in areas like language, communication, and self-care. Educational, pharmacological, and psychosocial approaches
Genetic counseling is a process that employs scientific knowledge of genetics and communication skills to help individuals understand genetic diagnoses and their implications. It involves gathering a family history, educating about genetic conditions and testing, and counseling to promote informed decision making. The goal is to address concerns relating to hereditary disorders and support adaptation to genetic risks or conditions.
The document discusses the diagnosis and conceptualization of ADHD from multiple perspectives. It notes that ADHD symptoms may represent an adaptive problem rather than a disorder, given evidence of genetic roots and neural plasticity. While diagnosis is important for communication and treatment, the classifications are temporary and shaped by current understanding, which continues to evolve with scientific advances.
This document provides an overview of genetic counseling. It defines genetics and genetic counseling, lists their objectives and components. It describes pedigree charting and the roles of the genetic counselor in providing information, estimating risk, and transmitting information to clients. Examples are given of different inheritance patterns and genetic disorders. The role of nurses in genetic counseling is outlined as receiving clients, obtaining family histories, providing support and information, encouraging questions, and maintaining privacy.
This document summarizes key aspects of child development from a biological perspective. It discusses the interplay between nature and nurture, including evidence from twin, adoption and feral studies. Genetic foundations are explored, including chromosomes, DNA, genes and inheritance. Common genetic conditions are described. The document also notes reproductive challenges and choices such as diagnostic tests, infertility treatments and adoption. Key frameworks for understanding genetic influences on development are presented.
Genetic Testing in Neonates and Children - Screening for developmental delay ...Prakash Patil
This document discusses genetic testing in neonates and children. It describes developmental delay and dysmorphism, the risk factors, types of delays, screening tests used to detect delays, treatment options, common dysmorphic features, and investigations for dysmorphism. Genetic testing can screen for developmental delays and birth defects through various prenatal and postnatal screening methods to facilitate early diagnosis and treatment.
Genetic Testing in Neonates and Children - Screening for chromosomal abnormal...Prakash Patil
Genetic testing in neonates and children can help diagnose congenital abnormalities. Around 1 in 35 children are born with congenital anomalies that affect development or functioning. Common birth defects in India include congenital heart disease, deafness, and neural tube defects. Genetic testing techniques like karyotyping, fluorescence in situ hybridization (FISH), chromosomal microarray analysis (CMA), and next generation sequencing (NGS) can help identify genetic disorders, chromosomal abnormalities, and mutations that cause congenital anomalies. Genetic testing provides medical benefits through diagnosis but also raises issues regarding psychological impacts, reproductive choice, and potential harms.
Psychiatric Outcomes in Young Children with a History of InstitutionalizationThiagoRibeiroMoreira1
Children raised in institutions, considered an extreme example of social deprivation, are one group through which we can better understand the impact of neglect on child health and development.
Genetic counseling is a process that provides information and support to individuals and families regarding genetic disorders and inherited diseases. It involves assessing family history, analyzing risks of conditions being passed down, and discussing options for preventing or diagnosing diseases. Genetic counselors are usually part of a medical team and help people understand their risk of conditions, make informed reproductive decisions, and cope with genetic testing results through education and psychological support. The goal is to allow individuals to make choices about their healthcare on an informed basis.
Genetic counselling,Genetic counselling whole processin ppt use for OBGsonal patel
Genetic counselling is a process that helps families with increased genetic risks by:
1. Communicating about genetic disorders, understanding diagnoses and management options, and assessing recurrence risks.
2. Helping families choose appropriate actions for their personal situation.
3. Adjusting to the psychosocial impacts of genetic conditions, such as guilt, blame, reproductive decisions, and effects on extended family.
The goal of genetic counselling is to help families with increased genetic risks live and reproduce normally by providing information, support, and guidance. It assists in situations like pregnant women at risk, families of newly diagnosed children, adults at risk of late-onset conditions, and relatives of those with X-linked disorders.
This document provides information about human genetics and genetic disorders, with a focus on Down syndrome. It defines genetic disorders and outlines different modes of genetic inheritance such as autosomal dominant, autosomal recessive, X-linked, and multifactorial inheritance. The document then describes Down syndrome in detail, including its causes, clinical features, investigations, screening and diagnosis, outcomes, and genetic counseling considerations.
The Ethics Review Board must balance the reproductive autonomy and health interests of patients with concerns about eugenics and discrimination. PGD may be permitted to avoid passing on serious genetic diseases like cystic fibrosis but not for traits like height. Producing cord cells to help an existing child with Fanconi's anemia could be allowed if the procedure is limited and does not become a gateway to other uses. Sex selection for family balancing requires further discussion due to societal implications.
The document discusses the stages of human development from fertilization through birth. It describes how a zygote is formed through the joining of an egg and sperm, and the early embryonic development of major organs over the first 8 weeks. The fetal stage from 8 weeks until birth is a period of rapid growth and differentiation, with the fetus increasing 20 times in length and developing functioning organs. The document also notes some potential problems in pregnancy like infertility, miscarriage, abortion, and threats to development from environmental factors and a mother's health behaviors during pregnancy.
This document provides an overview of child development for healthcare professionals. It defines development as the capacity to adapt to the environment through functional and physiological maturation. The main fields of development are motor, vision/fine motor, speech/language, and social/emotional. Development follows sequential and age-appropriate patterns in areas like motor skills. The document discusses assessing development through developmental milestones, screening tests, and evaluating potential causes of developmental delay.
Schizophrenia is a psychotic disorder marked by disturbances in thought, emotion, and behavior. It has both genetic and environmental risk factors. Genetic studies show higher concordance rates in identical twins compared to fraternal twins or other relatives. However, genes alone do not determine risk, as adoption studies show lower concordance rates in adopted-away relatives versus biological relatives. Prenatal exposures like viral infections and maternal stress during pregnancy may also impact risk by disrupting early brain development. Living with critical or over-involved family members after being discharged from the hospital predicts a higher rate of relapse. Both genetic and environmental factors likely interact to determine one's vulnerability to schizophrenia.
Genetic testing in neurology is becoming more common and offers potential for diagnosis confirmation and prognosis. The neurologist needs to be aware of testing indications, standards, and risks of inappropriate use. Genetic testing can be used for diagnostic, prenatal, predictive, carrier, and disease risk purposes, as well as pharmacogenetics. Providing counseling before and after testing is important to discuss implications and avoid misinterpretations of results.
The document provides an overview of genetic counseling. It defines genetic counseling as a process that helps people understand medical, psychological and familial implications of genetic contributions to disease. This involves interpreting family histories, providing education, facilitating informed decision making, and offering support. The document outlines the aims, indications, information conveyed, and steps involved in genetic counseling sessions. It also describes the roles of genetic counselors and nurses in counseling clients.
Genetic counseling involves evaluating a family's medical history and genetic test results to help them understand inherited disorders and make decisions. Genetic tests analyze blood or tissue samples to identify genes for disorders. Those who may benefit from genetic counseling have a family history of genetic disorders, birth defects, inherited cancers, intellectual disabilities, or recurrent miscarriages. Genetic counseling provides advice on the risks of inherited conditions being passed down and helps with decisions around prenatal testing, treatment, and family planning.
This document discusses genetics research on schizophrenia. It provides background on why genetics are studied for schizophrenia, defines key genetic terms, and outlines the major approaches taken in genetics research on schizophrenia including family studies, twin studies, adoption studies, linkage studies, and association studies. It summarizes some of the key findings from these genetic studies, such as higher concordance rates for schizophrenia in monozygotic twins compared to dizygotic twins, indicating a genetic component. Overall, the document provides an overview of the genetics research that has been conducted to understand the biological basis and inheritance of schizophrenia.
Gene counselling a developing field has more effect on both the developing and developed countries. So this ppt provides the basic idea about genetic counselling
This document discusses genetics and genetic disorders. It begins by defining genetics as the study of genes, genetic variation, and heredity. It then provides information on several genetic disorders including Huntington's disease, Down syndrome, cystic fibrosis, and Barth syndrome. For Huntington's disease specifically, it details the signs and symptoms, diagnosis through genetic testing, management through various treatments, and differential diagnosis compared to other conditions. It also provides details on the causes and diagnosis of Down syndrome.
This document discusses genetic counseling, including what it involves, classifications of genetic disorders, molecular bases of some disorders, and approaches to genetic counseling. It provides details on klinefelter syndrome, turner syndrome, and the philadelphia chromosome as examples. The document outlines the key elements of genetic counseling practice and discusses testing options like karyotyping, amniocentesis, and pedigree analysis. Prospective and retrospective counseling approaches are compared, along with considerations for when to see a genetic counselor.
Eugenics, behavioural genetics and genetic disorderssandeshGM
This document discusses eugenics, behavioural genetics, and genetic disorders. It defines eugenics as practices that aim to improve the genetic quality of humans. It discusses the origins and types of eugenics such as positive and negative eugenics. The document also defines behavioural genetics as examining genetic and environmental influences on behavior through studies like twin studies. It discusses research findings on genetic influences on behavior. Finally, it defines and provides examples of different types of genetic disorders like single gene disorders, multifactorial disorders, and X-linked, Y-linked, and mitochondrial disorders.
Anoop Venugopal is seeking a job where he can achieve personal and organizational goals in an environment of growth and excellence. He has a M.Tech in Embedded System Technology from SRM University and a B.Tech in Electronics and Communication Engineering. His work experience includes positions as a Process Consultant at Concentrix Corporation and a Technical Support Consultant at Sutherland Global Services. He has technical skills in operating systems, programming languages, microcontrollers, and protocols.
This document provides an introduction to polynomials. It defines what a polynomial is, listing examples of monomials, binomials, and trinomials. It discusses the degree of a polynomial as the highest power of the variable. It describes the different types of polynomials based on degree, such as linear, quadratic, and cubic polynomials. It explains concepts like the value of a polynomial for a given input, zero polynomials, and the remainder theorem. Examples of polynomials are provided throughout to illustrate the key concepts.
Genetic Testing in Neonates and Children - Screening for developmental delay ...Prakash Patil
This document discusses genetic testing in neonates and children. It describes developmental delay and dysmorphism, the risk factors, types of delays, screening tests used to detect delays, treatment options, common dysmorphic features, and investigations for dysmorphism. Genetic testing can screen for developmental delays and birth defects through various prenatal and postnatal screening methods to facilitate early diagnosis and treatment.
Genetic Testing in Neonates and Children - Screening for chromosomal abnormal...Prakash Patil
Genetic testing in neonates and children can help diagnose congenital abnormalities. Around 1 in 35 children are born with congenital anomalies that affect development or functioning. Common birth defects in India include congenital heart disease, deafness, and neural tube defects. Genetic testing techniques like karyotyping, fluorescence in situ hybridization (FISH), chromosomal microarray analysis (CMA), and next generation sequencing (NGS) can help identify genetic disorders, chromosomal abnormalities, and mutations that cause congenital anomalies. Genetic testing provides medical benefits through diagnosis but also raises issues regarding psychological impacts, reproductive choice, and potential harms.
Psychiatric Outcomes in Young Children with a History of InstitutionalizationThiagoRibeiroMoreira1
Children raised in institutions, considered an extreme example of social deprivation, are one group through which we can better understand the impact of neglect on child health and development.
Genetic counseling is a process that provides information and support to individuals and families regarding genetic disorders and inherited diseases. It involves assessing family history, analyzing risks of conditions being passed down, and discussing options for preventing or diagnosing diseases. Genetic counselors are usually part of a medical team and help people understand their risk of conditions, make informed reproductive decisions, and cope with genetic testing results through education and psychological support. The goal is to allow individuals to make choices about their healthcare on an informed basis.
Genetic counselling,Genetic counselling whole processin ppt use for OBGsonal patel
Genetic counselling is a process that helps families with increased genetic risks by:
1. Communicating about genetic disorders, understanding diagnoses and management options, and assessing recurrence risks.
2. Helping families choose appropriate actions for their personal situation.
3. Adjusting to the psychosocial impacts of genetic conditions, such as guilt, blame, reproductive decisions, and effects on extended family.
The goal of genetic counselling is to help families with increased genetic risks live and reproduce normally by providing information, support, and guidance. It assists in situations like pregnant women at risk, families of newly diagnosed children, adults at risk of late-onset conditions, and relatives of those with X-linked disorders.
This document provides information about human genetics and genetic disorders, with a focus on Down syndrome. It defines genetic disorders and outlines different modes of genetic inheritance such as autosomal dominant, autosomal recessive, X-linked, and multifactorial inheritance. The document then describes Down syndrome in detail, including its causes, clinical features, investigations, screening and diagnosis, outcomes, and genetic counseling considerations.
The Ethics Review Board must balance the reproductive autonomy and health interests of patients with concerns about eugenics and discrimination. PGD may be permitted to avoid passing on serious genetic diseases like cystic fibrosis but not for traits like height. Producing cord cells to help an existing child with Fanconi's anemia could be allowed if the procedure is limited and does not become a gateway to other uses. Sex selection for family balancing requires further discussion due to societal implications.
The document discusses the stages of human development from fertilization through birth. It describes how a zygote is formed through the joining of an egg and sperm, and the early embryonic development of major organs over the first 8 weeks. The fetal stage from 8 weeks until birth is a period of rapid growth and differentiation, with the fetus increasing 20 times in length and developing functioning organs. The document also notes some potential problems in pregnancy like infertility, miscarriage, abortion, and threats to development from environmental factors and a mother's health behaviors during pregnancy.
This document provides an overview of child development for healthcare professionals. It defines development as the capacity to adapt to the environment through functional and physiological maturation. The main fields of development are motor, vision/fine motor, speech/language, and social/emotional. Development follows sequential and age-appropriate patterns in areas like motor skills. The document discusses assessing development through developmental milestones, screening tests, and evaluating potential causes of developmental delay.
Schizophrenia is a psychotic disorder marked by disturbances in thought, emotion, and behavior. It has both genetic and environmental risk factors. Genetic studies show higher concordance rates in identical twins compared to fraternal twins or other relatives. However, genes alone do not determine risk, as adoption studies show lower concordance rates in adopted-away relatives versus biological relatives. Prenatal exposures like viral infections and maternal stress during pregnancy may also impact risk by disrupting early brain development. Living with critical or over-involved family members after being discharged from the hospital predicts a higher rate of relapse. Both genetic and environmental factors likely interact to determine one's vulnerability to schizophrenia.
Genetic testing in neurology is becoming more common and offers potential for diagnosis confirmation and prognosis. The neurologist needs to be aware of testing indications, standards, and risks of inappropriate use. Genetic testing can be used for diagnostic, prenatal, predictive, carrier, and disease risk purposes, as well as pharmacogenetics. Providing counseling before and after testing is important to discuss implications and avoid misinterpretations of results.
The document provides an overview of genetic counseling. It defines genetic counseling as a process that helps people understand medical, psychological and familial implications of genetic contributions to disease. This involves interpreting family histories, providing education, facilitating informed decision making, and offering support. The document outlines the aims, indications, information conveyed, and steps involved in genetic counseling sessions. It also describes the roles of genetic counselors and nurses in counseling clients.
Genetic counseling involves evaluating a family's medical history and genetic test results to help them understand inherited disorders and make decisions. Genetic tests analyze blood or tissue samples to identify genes for disorders. Those who may benefit from genetic counseling have a family history of genetic disorders, birth defects, inherited cancers, intellectual disabilities, or recurrent miscarriages. Genetic counseling provides advice on the risks of inherited conditions being passed down and helps with decisions around prenatal testing, treatment, and family planning.
This document discusses genetics research on schizophrenia. It provides background on why genetics are studied for schizophrenia, defines key genetic terms, and outlines the major approaches taken in genetics research on schizophrenia including family studies, twin studies, adoption studies, linkage studies, and association studies. It summarizes some of the key findings from these genetic studies, such as higher concordance rates for schizophrenia in monozygotic twins compared to dizygotic twins, indicating a genetic component. Overall, the document provides an overview of the genetics research that has been conducted to understand the biological basis and inheritance of schizophrenia.
Gene counselling a developing field has more effect on both the developing and developed countries. So this ppt provides the basic idea about genetic counselling
This document discusses genetics and genetic disorders. It begins by defining genetics as the study of genes, genetic variation, and heredity. It then provides information on several genetic disorders including Huntington's disease, Down syndrome, cystic fibrosis, and Barth syndrome. For Huntington's disease specifically, it details the signs and symptoms, diagnosis through genetic testing, management through various treatments, and differential diagnosis compared to other conditions. It also provides details on the causes and diagnosis of Down syndrome.
This document discusses genetic counseling, including what it involves, classifications of genetic disorders, molecular bases of some disorders, and approaches to genetic counseling. It provides details on klinefelter syndrome, turner syndrome, and the philadelphia chromosome as examples. The document outlines the key elements of genetic counseling practice and discusses testing options like karyotyping, amniocentesis, and pedigree analysis. Prospective and retrospective counseling approaches are compared, along with considerations for when to see a genetic counselor.
Eugenics, behavioural genetics and genetic disorderssandeshGM
This document discusses eugenics, behavioural genetics, and genetic disorders. It defines eugenics as practices that aim to improve the genetic quality of humans. It discusses the origins and types of eugenics such as positive and negative eugenics. The document also defines behavioural genetics as examining genetic and environmental influences on behavior through studies like twin studies. It discusses research findings on genetic influences on behavior. Finally, it defines and provides examples of different types of genetic disorders like single gene disorders, multifactorial disorders, and X-linked, Y-linked, and mitochondrial disorders.
Anoop Venugopal is seeking a job where he can achieve personal and organizational goals in an environment of growth and excellence. He has a M.Tech in Embedded System Technology from SRM University and a B.Tech in Electronics and Communication Engineering. His work experience includes positions as a Process Consultant at Concentrix Corporation and a Technical Support Consultant at Sutherland Global Services. He has technical skills in operating systems, programming languages, microcontrollers, and protocols.
This document provides an introduction to polynomials. It defines what a polynomial is, listing examples of monomials, binomials, and trinomials. It discusses the degree of a polynomial as the highest power of the variable. It describes the different types of polynomials based on degree, such as linear, quadratic, and cubic polynomials. It explains concepts like the value of a polynomial for a given input, zero polynomials, and the remainder theorem. Examples of polynomials are provided throughout to illustrate the key concepts.
This document outlines plans to establish a tiny home village in Huntsville, Alabama to help address homelessness. The village will be run by the nonprofit Foundations for Tomorrow and will partner with other organizations to provide 30 tiny homes, community buildings, and access to services to help homeless individuals transition back into housing. Tiny homes cost significantly less than other housing options and can help reduce costs associated with homelessness. The village will be self-governed and provide residents a safe, legal place to live while they work to become self-sufficient.
The document discusses the IT sector and its growth. It states that information technology has changed the world over the past decade by becoming integrated into almost all industries. The IT field has experienced rapid growth in recent years and is expected to continue growing steadily according to experts. Millions of jobs have been created by the IT sector in India, which has become a popular outsourcing destination for its ability to offer round-the-clock services at a lower cost while maintaining quality. Some major Indian IT companies that provide good career opportunities include Infosys, TCS, Wipro, and Tech Mahindra.
ACC 544 Final Exam Answers
1) Which is NOT one of the AICPA’s Code of Professional Conduct principles?
A. The public interest
B. Integrity
C. Quality control
D. Scope and nature of services
2) The ethical philosophy that considers the consequences of similar persons acting under similar circumstances is called
A. utilitarian principle.
B. imperative principle.
C. categorical imperative.
D. generalization argument.
3) The fundamental issues in independence require that the auditor avoid
A. financial connections with the client and financial connections with the client’s competitors.
B. acting as management and representing the shareholder’s interests.
C. responsibility for the client’s internal control and subordinating judgment concerning audit issues.
D. financial connections with the firm and acting as management.
4) Auditors have greater liability under the Securities Act of 1933. Which is the reason that this greater liability exis
An in-depth visual about creating responsive website designs that appeal to modern Internet users, improve engagement, and increase search engine rankings (SEO).
With an ever growing range of devices connecting to the internet and a variety of screen sizes available, there’s more pressure than ever to create websites that work well and look great no matter what device they’re being viewed on.
Responsive website design is the solution.
Responsive Web design simplifies the process of adapting your site to any screen size. This in turn will “future proof” your site for years to come. Users will have a much more satisfying experience when viewing your site, allowing you to focus on delivering your intended message. Your site’s search engine rankings will be improved, meaning that your site’s visibility will increase.
A modern website has the ability to reach your target audience in new and ever-changing ways. We will cover the recent trending website topics and discuss content creation, brand development, social media and other marketing strategies that support your Web presence efforts.
Supportninja | We scale startups, with Ninjas.supportninja
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Hamilton Youth Engagement Initiative : Year in Review 2011-2012Alex Ramirez
This document provides a review and policy recommendations from the Hamilton Youth Engagement Initiative for 2011-2012. It outlines the mission and methodology of engaging youth through focus groups and peer mentorship. Policy recommendations were developed by students at six Hamilton secondary schools and ratified at a Youth Summit. The recommendations address issues identified by youth such as the need for adolescent recreation centers, stronger laws around pet ownership to reduce strays, and installing water filtration systems in schools to improve drinking water quality. The initiative aims to foster youth civic engagement and provide their perspectives to influence municipal policies and decisions.
This document provides information on various cephalosporin antibiotics including their dosage, half-life, use in children, need for renal or hepatic dose adjustment, central nervous system penetration, and key characteristics. Some of the antibiotics discussed include cefotaxime, ceftazidime, ceftriaxone, cefpodoxime, ceftibuten, and cefdinir. The document provides brief summaries of each antibiotic's spectrum of activity, dosing recommendations, and pharmacological properties.
This document summarizes chapter 1 of an AP psychology case study textbook. It discusses how each chapter will present a case report and diagnosis using the DSM-5. It covers the stigma of labeling psychological disorders and the 5 criteria used. The chapter also discusses the history of treatment for psychologically disturbed individuals and the importance of clinical research and evidence-based treatments. Key terms like client, patient, and clinician are defined, and the diagnostic process is outlined. Cultural factors like cultural bound syndromes and cultural formulations are also highlighted.
The document discusses several topics related to women in stem cell science:
1. Women are underrepresented among senior stem cell scientists but make up about 40% of junior faculty. More work is needed to improve the pipeline for underrepresented minority women.
2. Women lag behind men in starting companies and obtaining patents from their research, reducing opportunities for their discoveries to reach patients and for them to receive credit.
3. Workplace culture must better support balancing family and work obligations to retain women scientists.
4. The document analyzes how science both reflects and reinforces gender theories, and discusses debates around stem cell derivation and the moral status and sexing of embryos.
This document provides an overview of Maria Holmes' genetics disorders unit portfolio presentation. The unit will study selected genetic disorders that primarily target certain ethnic and gender groups. It will examine the causes, symptoms, testing, and frequency of disorders like cystic fibrosis, sickle cell anemia, and hemophilia. The goals are for students to understand genetics, analyze genetic disorder data, and communicate their knowledge in a brochure.
Disrupting drug discovery one disease at a timeSean Ekins
This document discusses efforts to accelerate research for rare disease MPSIIIC through open science and partnerships. An organization called Jonah's Just Begun is partnering with scientists, clinicians, other patient groups, and a company called Phoenix Nest to pursue multiple treatment approaches including gene therapy, substrate reduction, and mutation correction. Early diagnosis of the main patient Jonah allowed early intervention and the formation of a global network to share knowledge and accelerate research that may find treatments in his lifetime. Open data sharing, patient engagement, and disrupting traditional models are seen as ways to further progress. Support is needed for increased awareness, diagnostics, and funding to move the efforts beyond the current scope.
This document discusses lifespan development and the nature vs. nurture debate. It covers several key topics related to this debate, including:
- Examples of how both nature and nurture influence traits like athletic ability.
- Differences between studying nature and nurture in animals vs. humans due to ethical and logistical challenges in human research.
- Research methods used to study nature and nurture such as adoption studies, twin studies, and heritability coefficients.
- Genetic foundations of development including DNA, genes, chromosomes, genetic principles, and examples of genetic abnormalities.
- Prenatal development stages from conception through birth and potential prenatal hazards like teratogens, drugs, and malnutrition.
Put to the test as genetic screening gets cheaper and easier,.docxamrit47
Put to the test: as genetic screening gets cheaper and easier, it's raising questions that health-
care providers aren't prepared to answer
The American Prospect, November 2010
When my children were born in the mid-1990s, new parents could already see that prenatal genetic
testing was altering the terrain of pregnancy and childbirth. Growing numbers of educated women were
having children at older ages, with resulting difficulties and risks. More and more parents faced
challenging, deeply personal decisions about whether to engage in genetic testing and what to do if they
received unfavorable results.
I remember my own anxieties when my wife, Veronica, took a blood test that searched for elevated
alpha-fetoproteins, which are associated with diverse ailments ranging from spina bifida to
anencephaly. The mere prospect of these rare conditions--and even the choice to undergo the tests--
was surprisingly painful. At least genetic counselors and other professionals were available to help guide
us.
By that point, amniocentesis had been in wide use for more than two decades. As researchers identified
the genetic markers associated with a growing list of important conditions, educated, secular, and
affluent communities began to embrace genetic testing. A small but lucrative market in assisted
reproductive technologies quickly emerged, which provided parents with greater control over the
genetic characteristics of their offspring. In some parts of America, new diagnostic technologies
provoked unease regarding their eugenic potential.
In retrospect, these innovations were incredibly tame. Technological limits, cost, intrusiveness, and risk
constrained the scope of screening efforts. Roughly one in every 200 amniocenteses resulted in
miscarriage, which made the procedure too risky to justify screening the full population of pregnant
women. The human genome had yet to be sequenced. Newborn screening was routinely used to
identify a handful of important metabolic disorders, but it was a very expensive process. There was a
certain clarity, too. The most common use of amniocentesis was (and remains) to detect conditions
associated with very serious physical or intellectual disabilities. When such conditions were detected,
most parents chose to terminate the pregnancy.
Fast forward to 2010. Prospective parents can now be tested before pregnancy, and those found to be
carriers for serious conditions have the option of in-vitro fertilization, whereby embryos can be pre-
tested for genetic markers associated with Alzheimer's disease, hemophilia, muscular dystrophy, Tay-
Sachs disease, and more. Many of these same markers can also be detected by do-it-yourself genetic-
testing kits, which are beginning to appear on the Internet and on drugstore shelves. Walgreens may
soon sell a cheap home test that covers 37 genetic conditions. (Sales are postponed pending approval by
the Federal Drug Administration.) You will soon ...
General Psychology Interpret an instance of behavior (individual .docxlianaalbee2qly
General Psychology
: Interpret an instance of behavior (individual or collective) recently in the news from the point of view of any two of the three schools of thought that became popular when psychology emerged as a discipline. Your response should include specific details including the major theorists and goals of the two selected schools of psychological thought. Your response should be at least 200 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. Wade, C., Tavris, C., & Garry, M. (2014). Psychology (11th ed.). Upper Saddle River, NJ: Pearson Education. Must be done in APA format
ONE PAGE /275 WORDS ONE SOURCE BOOK REFERENCE
[1/29/16, 11:29 AM] josphat mungai (
[email protected]
):
Author: R.A. Noe
Employee training and development (6th ed.). New York, NY: McGraw-Hill
2:General Psychology
: A researcher hypothesizes that adults will respond differently to the same baby depending on how the child is dressed. Her colleague, on the other hand, hypothesizes that boys and girls are treated equally and that only temperamental differences lead to differences in their handling. Design a research study to test their hypotheses. Your response should be at least 200 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. Wade, C., Tavris, C., & Garry, M. (2014). Psychology (11th ed.). Upper Saddle River, NJ: Pearson Education. Must be done in APA format
ONE PAGE /275 WORDS ONE SOURCE BOOK REFERENCE
[1/29/16, 11:29 AM] josphat mungai (
[email protected]
):
Author: R.A. Noe
Employee training and development (6th ed.). New York, NY: McGraw-Hill
Put to the test: as genetic screening gets cheaper and easier, it's raising questions that health-care providers aren't prepared to answer
The American Prospect, November 2010
When my children were born in the mid-1990s, new parents could already see that prenatal genetic testing was altering the terrain of pregnancy and childbirth. Growing numbers of educated women were having children at older ages, with resulting difficulties and risks. More and more parents faced challenging, deeply personal decisions about whether to engage in genetic testing and what to do if they received unfavorable results.
I remember my own anxieties when my wife, Veronica, took a blood test that searched for elevated alpha-fetoproteins, which are associated with diverse ailments ranging from spina bifida to anencephaly. The mere prospect of these rare conditions--and even the choice to undergo the tests--was surprisingly painful. At least genetic counselors and other professionals were available to help guide us.
By that point, amniocentesis had been in wide use for more than t.
Tipik atipik gelişim: otizm örneği üzerinden tartışma Yanki Yazgan
Koç Üniversitesinde verilmiş konferans. Bir kısmı daha önce Haseki Nöroloji'de verdiğim konferanstan. Üzerinde durduğum normal ile anormal arasındaki ayrımın düşündüğümüzden çok daha silik olduğu, ikisi arasındaki geçişliliğin yüksek olduğu kanısı üzerine. Yarı İngilizce yarı Türkçe, kusura bakmayın. Ancak yetişiyor:)
Child Development in the Broader Context of Developmental Science.docxbissacr
Child Development in the Broader Context of Developmental Science
Child development is one aspect of the broader, interdisciplinary field of developmental science, which includes the entire lifespan. Researchers in the area of child development typically divide these initial years into five age periods encompassing conception through adolescence.
PRENATAL PERIOD
INFANCY AND TODDLERHOOD
EARLY CHILDHOOD PERIOD
MIDDLE CHILDHOOD PERIOD
ADOLESCENT PERIOD
Vygotsky’s Sociocultural Theory
Does society or culture have an impact on child development? Of course! Each individual has a different religious, ethnic, and economic background. Since all of those factors influence our development, there has been a rise in research studies that address the cultural context of children’s lives. Researchers are examining the effect of culturally specific beliefs and practices on development.
Sociocultural theory, developed by Lev Vygotsky, focuses on how culture is transmitted to the next generation. Vygotsky believed that social interaction with more knowledgeable members of society is necessary for children to develop the ways of thinking and behaving that comprise a community’s culture. He saw cognitive development as a socially mediated process in which children depend on assistance from peers and adults as they take on new challenges. One additional discovery of cross-cultural research is that each individual culture may emphasize different tasks for childr
Ecological Systems Theory
Urie Bronfenbrenner (1917–2005) posited that our environment, consisting of our home, school, neighborhood, and beyond, is a series of structures that form a system. Each layer of that system interacts with the others and has a powerful impact on development. According to Bronfenbrenner’s ecological systems theory, children develop within this complex system of relationships and are affected by multiple levels of the surrounding environment.
MICROSYSTEM
MESOSYSTEM
EXOSYSTEM
MACROSYSTEM
CHRONOSYSTEM
An Illustration of Ecological Systems Theory: The Transition to Siblinghood
The early weeks after a new baby enters the family are full of profound changes. While the arrival of a newborn sibling is a normative life event for many children, the transition to siblinghood can result in a mixture of positive and negative emotions. Some children welcome the new arrival, while others experience a developmental setback in a specific area like toilet training. Volling (2005) provides a developmental ecological systems approach to examine changes in both child and family functioning that occur with the birth of a new baby.
‹ 1/5 ›
Significant changes occur within the immediate family (microsystem). Because the mother may spend most of the early weeks after the birth caring for the newborn, the quality of the father–child relationship may be particularly important for sibling adjustment.
Development as a Dynamic System
According to a theory known as dynamic systems perspective, a child.
Leading Australian Rett Syndrome researcher, Professor Helen Leonard's presentation from the Respite Plus Beyond Respite Forum, 2014 held at Twin Waters Resort, Sunshine Coast Australia
Genomic sequencing of cancer patients can provide key information about the tumor and identify which genes are involved in its development. Sequencing the exome of a cancer patient's tumor can determine if the growth is due to oncogenes or tumor suppressor genes, allowing treatment to be tailored specifically for that patient. One application is identifying the presence of the HER-2 oncogene in breast cancer patients, which can be targeted by HER-2-directed therapies if amplified. Genome sequencing personalized cancer treatment based on the genetic profile of an individual's tumor.
This newsletter provides an annual update from the Harris Center for Education and Advocacy in Eating Disorders at Massachusetts General Hospital. It discusses the Center's activities over the past year, including conducting research, educating new scientists through fellowship programs, publishing educational materials for families, and hosting public awareness forums. The newsletter announces plans for a $2 million research campaign and introduces the Center's new postdoctoral fellow. It provides updates on the research and activities of the Center's directors and associates.
Nature-Nurture (Heredity vs environment) Backgro.docxdohertyjoetta
Nature-Nurture
(Heredity vs environment)
Background
It has long been known that certain physical characteristics are biologically determined by
genetic inheritance. Colour of eyes, straight or curly hair, pigmentation of the skin and certain
diseases (such as Huntingdon’s chorea) are all a function of the genes we inherit. Other physical
characteristics, if not determined, appear to be at least strongly influenced by the genetic make-
up of our biological parents. Height, weight, hair loss (in men), life expectancy and vulnerability
to specific illnesses (e.g. breast cancer in women) are positively correlated between biologically
related individuals. These facts have led many to speculate as to whether psychological
characteristics such as behavioural tendencies, personality attributes and mental abilities are also
“wired in” before we are even born.
Those who adopt an extreme heredity position are known as nativists. Their basic assumption is
that the characteristics of the human species as a whole are a product of evolution and that
individual differences are due to each person’s unique genetic code. Characteristics and
differences that are not observable at birth, but which emerge later in life, are regarded as the
product of maturation. That is to say we all have an inner “biological clock” which switches on
(or off) types of behaviour in a pre programmed way. The classic example of the way this affects
our physical development is the bodily changes that occur in early adolescence at puberty.
However nativists also argue that maturation governs the emergence of attachment in infancy,
language acquisition and even cognitive development as a whole.
At the other end of the spectrum are the environmentalists – also known as empiricists (not to be
confused with the other empirical / scientific approach). Their basic assumption is that at birth
the human mind is a tabula rasa (a blank slate) and that this is gradually “filled” as a result of
experience (e.g. behaviourism). From this point of view psychological characteristics and
behavioural differences that emerge through infancy and childhood are the result of learning. It is
how you are brought up (nurture) that governs the psychologically significant aspects of child
development and the concept of maturation applies only to the biological. So, when an infant
forms an attachment it is responding to the love and attention it has received, language comes
from imitating the speech of others and cognitive development depends on the degree of
stimulation in the environment and, more broadly, on the civilisation within which the child is
reared.
In practice hardly anyone today accepts either of the extreme positions. There are simply too
many “facts” on both sides of the argument which are inconsistent with an “all or nothing” view.
So instead of asking whether child development is down to nature or nurture the question has
been reformulated as .
Handedness and the Diverse Gender-Related Personality Traits i.docxwhittemorelucilla
Handedness and the Diverse Gender-Related Personality Traits in Humans
Handedness and the Diverse Gender-Related Personality Traits in Humans
Sejla Husic
FSCJ South Campus
Handedness and the Diverse Gender-Related Personality Traits in Humans
According to recent meta-analysis, there has been an immoderate amount of
information linked between the likeliness of sexual orientation and laterality. Using one hand
more than the other. The significant data from 6,182 homosexual and 14,808 heterosexual men,
showed that homosexual men had 34% greater odds of being non-right handed than heterosexual
men, and data from 805 homosexual and 1,615 heterosexual women had 91% greater odds of
being non- right handed than heterosexual women RichardA.Lippa,Ph.D.1 Other gender-
atypicality has been linked to this finding, one would be gender identity disorder. In an
international survey, more than 11,000 participants, documented that 10.6% of males and 8.5%
of females are at higher rates of heft- handedness. Even though the number of theories found of
small but reliable gender differences found in handedness, the results remain poorly understood.
Prenatal Androgen Theory is the most reasonable explanation of homosexuality in
the social behavior of human genders. Stating the sexual orientation is established in the womb
during fetal development. Although with more higher androgen exposure, comes more gender
typical patterns of development, in the males case it would be a greater chance of left-
handedness. Corresponding to gender- related personality traits, within sexual orientation groups,
non- right handedness is associated with masculine traits for both sexes. Predictions have been
made based on simple linear version of prenatal hormone theory, the androgens masculinize
behavior between sex and then is compared on average (James, 1989). Consequently there has
been strong data shown the prenatal hormone theory of handedness, concluding that the non-
right-handedness occurs more in the males sex than females.
Handedness and the Diverse Gender-Related Personality Traits in Humans
Neurological and developmental problems can be the cause of so many theories.
For instance the Pathological left- handedness theory, stating that left-handedness is caused by
pathological stressors, as in birth traumas, or cerebrum impairments. Evidence has proven that
left-handedness is associated with numerous cognitive developmental problems, including
learning disabilities, intellectual retardation, autism, cerebral palsy, etc. (Previc,1996). An
argument has been made that moderate right-handedness is the optimal evolved human trait and
therefore that developmental instability leads both to non-right ...
Mental health%20 problems_early%20childhoodRenata Costa
Mental health problems can emerge early in childhood and impair learning and behavior if left unaddressed. Significant adversity like abuse, neglect, poverty or family mental illness can damage the developing brain and increase risks for later mental health issues. While all children facing prolonged adversity are vulnerable, genetics also play a role - some children are more susceptible to stress. Early intervention can help address emerging problems and improve outcomes, but young children often express mental health issues differently than older children and adults due to differences in brain development, self-awareness and relationships. Untreated difficulties that start early may worsen over time into more serious disorders.
This document discusses challenges in diagnosing disorders related to dysmorphology and genetics in pediatric patients. It notes that an accurate diagnosis can be difficult due to genetic heterogeneity, environmental factors, incomplete family histories, and other issues. The document emphasizes the importance of a thorough clinical examination, family history, and integrating multiple sources of data to establish a diagnosis. It also discusses how early diagnosis can provide benefits by informing clinical management and prognosis.
This document provides guidance on responsible research practices for psychologists. It discusses proper procedures and potential violations for collaborating on research projects, managing conflicts of interest and commitments, acquiring and sharing data, conducting human subject research, ensuring animal welfare, and mentoring less experienced researchers. Key aspects of responsible research addressed include clearly defining roles and goals for collaboration, properly addressing any financial or personal biases, making data publicly available whenever possible, obtaining informed consent and minimizing harm for human and animal subjects, and maintaining appropriate boundaries in mentoring relationships.
This document summarizes key chapters from the 9th edition of the psychology textbook "Psychology" by David G. Myers. The summary covers several chapters that discuss the interplay between nature and nurture in human development. Specifically, it examines how genes, early family experiences, culture, gender roles, and the environment all influence human diversity in traits such as personality, intelligence and behavior. The document emphasizes that most psychological characteristics are influenced by both biological and environmental factors interacting together, rather than being solely determined by either nature or nurture.
2. This question
frequently arises
from families, educa-
tors, and community
members who eagerly
await answers that
will improve their
lives or the lives of
those they care about.
Discovery begins with ideas born of a
deep knowledge of the research of
predecessors and colleagues. Sudden insights
do happen, but typically only after ideas
ferment, after bouncing them about with
colleagues, students, clinicians, families, in
seminars, journal clubs, clinics, rounds, or
over coffee. Vanderbilt and the VKC offer
superb settings for forming ideas,
collaborating in interdisciplinary teams, and
using cutting-edge research facilities.
After honing ideas, they must be tested to
justify larger federal or other investments. At
this point, seed monies and Hobbs Discovery
Grants become critically important! With
preliminary findings in hand, scientists pour
their passion into grants to the National
Institutes of Health (NIH), National Science
Foundation, and other federal or philan-
thropic agencies. Writing and submitting a
grant, getting reviews, resubmitting a revision,
succeeding at funding is often a 2-year process.
Once funded, researchers deal with study
logistics. They obtain approval by the
Institutional Review Board, hire the best staff
and students, recruit research participants or
develop cell cultures or animal models.
Problems are solved daily in the nitty-gritty of
collecting and analyzing data. Finally, findings
come in, but even the most exhilarating,
groundbreaking findings must be checked
and re-examined. Only then do scientists
prepare their findings in manuscripts
submitted to well-respected scientific journals
for peer review. This process can take months,
and it is sometimes a year or more until the
article appears electronically or in print.
Research participants, too, deserve to know
what’s been learned.
We became scientists because we love
discovery, yet we also teach courses, mentor
students, serve on committees, and
administer departments, centers, clinics, and
programs. We review the studies of other
scientists, serve on federal committees and
review panels, and contribute to our field.
All is in the service of science—but at a cost
of time away from our labs.
Then, life and politics happen! Beyond
experiencing life events we all share (ill
parents, children with school difficulties),
we are impacted by politics. As I write, on the
first day of our nation’s sequester, we await
news from the NIH and other federal
agencies about how they will cut budgets for
the research we have painstakingly developed.
Now more than ever, please transform
your impatience for research answers into
actions to help us on the road to discovery.
Donate to a Hobbs Discovery Grant Award,
participate in a study, fund a student
scholarship, or let your political
representatives know how important research
on developmental disabilities is for your
family. Discovery requires all of us working
together.
DIRECTOR’S MESSAGE: WHY DOES RESEARCH TAKE SO LONG?
Elisabeth Dykens
This Discovery Special Issue addresses “Why?” Why is discovery needed in the field of intellectual and developmental disabilities? Why do
persons with and without disabilities contribute to the field? Why do scientists and students choose their areas of work? Why do we
blend research, service, training, and public policy? By answering such questions, we aim to illuminate the challenging pathway from ideas
to practices and how families, researchers, clinicians, students, and trainees walk this pathway together.
Genetics
Intellectual
disability
that “runs in
families”
Characterized
by “fragile”
piece of X
chromosome
Diagnostic
cytogenetic
techniques
developed
Sherman Paradox “skips
generation” (unaffected
carrier fully affected
son)
• Caused by expanding
repeat in FMR1 gene
• PCR screen/
diagnosis developed
• Some females (vs. males) with full
mutation mildly affected
• mGluR pathways underlie many FXS
characteristics
Unexpected
Discoveries
FXS & autism linked • In older FXS persons, FXTAS gene leads
to characteristics of Parkinson, Alzhei-
mer, Charcot-Marie-Tooth syndromes
• Older gene male carriers at high risk of
developing FXTAS
• Cerebellum atypical development
related to FXS & autism phenotypes
but different regions contribute to each
phenotype
InterventionsBehavior
• FXS males have cogni-
tive, linguistic, &
adaptive strengths &
weaknesses
• Older vs. younger males
show more severe delays
• FXS females at risk for
schizoaffective &
affective illnesses
• FXS male IQs
decrease over time
• IQ decrease may
relate to methylation
• In FXS young children, low receptive
language may be marker for autism
symptoms
• Autistic behaviors in FXS girls
associated with poorer developmental
outcomes
• Cf. FXS alone, children with FXS & autism
have more difficulty with imitation
• At equated cognitive
levels, social reciprocity
similar in persons with
FXS vs. autism
• Parents of FXS children
have higher rates of
rigid personality
1940 1960 1970 1980 1990 2000 2010
• Calming techniques
useful
• Visual approaches
(rebus symbols) for
reading-math
• mGluR5 negative
allosteric modulator
AFQ056 may improve
aberrant behavior in
adults with FXS who have
full methylation of FMR1
• Arbaclofen may improve
social function & behavior
This timeline illustrates the lengthy, complex
process of research in developmental disabili-
ties. Although FXS was recognized in 1943 as
an intellectual disability that “ran in families,”
it took another 26 years to identify the genetic
cause and another 10 years to develop
diagnostic techniques. Fifty years later, the
genetic complexity continues to be unraveled.
Not until the 1980s, 40 years later, did
researchers characterize the behavioral
complexity in males vs. females, carriers vs.
affected offspring, with insights continuing
today. Behavioral interventions were developed
50 years later; 70 years later, pharmacological
interventions are emerging.
In the course of research, unexpected
discoveries emerge, such as the way that
previously thought “unaffected” carrier males
are prone to Parkinson and other conditions.
These advances lead to new directions, not
only for the disorder being studied but also
for other disorders and health conditions in
the general population.
Progress on FXS has been made by many
researchers over 70 years and continues today,
with effective interventions still being sought—
an example of discovery as a collaborative and
cumulative process.
FRAGILE X SYNDROME (FXS) DISCOVERY TIMELINE
3. DISCOVERY | Winter 2013 3
The Rock Stars of Science
(Rock S.O.S.) national
campaign featured
dramatic photos of
scientists with celebrities.
Initiated by the Geoffrey
Beene Foundation, the
goal was to raise
awareness that science,
science education, and
science funding should
be a national priority.
In a Rock S.O.S. video,
Anthony Fauci, M.D.,
director of the National
Institute of Allergy and
Infectious Diseases,
described science as
“a career of making
contributions to society
…. Society would benefit
greatly if more people
would go into science.”
The Vanderbilt
Kennedy Center
celebrates the 210 faculty
scientists from 26
disciplines who work
daily to understand
development and
developmental disabilities
and to improve the
lives of persons with
developmental disabilities
and their families. Each
mentors students who
are the future of our
nation’s science. Here we
highlight a few. Every
VKC scientist is a
Rock Star of Intellectual
and Developmental
Disabilities Science!
WHY VKC SCIENTISTS ROCK!
Shari Barkin, M.D.
Pediatrics
PEDIATRIC OBESITY
INTERVENTION AND
PREVENTION
Ana Carneiro, Ph.D.
Pharmacology
MONOAMINE
DYSREGULATION IN AUTISM,
ADHD, AND OCD
Roger Colbran, Ph.D.
Molecular Physiology &
Biophysics
CELL AND SYNAPTIC SIGNAL-
ING DURING TYPICAL AND
ATYPICAL DEVELOPMENT
Kevin Erreger, Ph.D.
Molecular Physiology &
Biophysics
DOPAMINE TRANSPORTER
AND LEARNING, MEMORY,
AND ADDICTION
Kevin Ess, Ph.D., M.D.
Neurology
CELLULAR MECHANISMS OF
TUBEROUS SCLEROSIS COM-
PLEX, SEIZURES, AND AUTISM
Joshua Gamse, Ph.D.
Biological Sciences
SCHIZOPHRENIA/XLMR
GENES AND BRAIN ASYM-
METRY USING ZEBRAFISH
Judy Garber, Ph.D.
Psychology
PREVENTION AND TREAT-
MENT OF EMOTIONAL
DISORDERS IN CHILDREN
AND ADOLESCENTS
Isabel Gauthier, Ph.D.
Psychology
FACE AND OBJECT
RECOGNITION IN AUTISM
Suzanne Goldman, Ph.D.
Neurology, Sleep Division
SLEEP DISORDERS IN AUTISM
AND IN ANGELMAN AND
WILLIAMS SYNDROMES
Elizabeth Hammock, Ph.D.
Pediatrics
GENES AND NEURAL
CIRCUITS IN SOCIAL/
EMOTIONAL DEVELOPMENT
Sasha Key, Ph.D.
Hearing & Speech Sciences
BRAIN FUNCTIONING AND
COGNITION IN GENETIC
SYNDROMES AND AUTISM
Bruce McCandliss, Ph.D.
Psychology
BRAIN DIFFERENCES AND
BRAIN CHANGES RELATED TO
LEARNING SUCCESS IN READ-
ING, MATH, AND ATTENTION
KarolyMirnics,M.D.,Ph.D.
Psychiatry
EFFECTS OF ENVIRONMENT
ON GENE EXPRESSION IN
AUTISM
Paul Newhouse, M.D.
Psychiatry
COGNITIVE IMPAIRMENT IN
OLDER ADULTS WITH DOWN
SYNDROME
Nilanjan Sarkar, Ph.D.
Mechanical Engineering
ROBOTICS AND VIRTUAL
REALITY FOR AUTISM
INTERVENTIONS
Julie Lounds Taylor, Ph.D.
Pediatrics
YOUTH WITH AUTISM AND
TRANSITION TO ADULTHOOD
4. PATHWAY
WHY PERSONS WITH DISABILITIES AND
FAMILY MEMBERS ARE PARTNERS
Roxanne Kennerly
Parent, Advocate
Being involved with the VKC has been life
changing, for my sons and myself. We have
all taken part in studies. With each, we
gained more knowledge, a new skill, or
made contributions. Language studies for
Ian have provided cutting-edge interventions.
Liam has taken part in sibling research and
SibSaturdays. I also feel satisfaction knowing
that we are helping others.
John Donovan
Sibling and Advocate
ThroughTABS [Tennessee Adult Brothers and
Sisters], I’ve met other siblings with similar
experiences.TABS also introduced me to
other VKC programs and to organizations such
asThe Arc, Sibling Leadership Network, and
many more.TABS has helped me become a
better brother and has given me the
opportunity to help others.
Karina Scali
College Student, Volunteer, Advocate
I always felt that I was born into this world
with Williams syndrome for a reason—to help
in any way I can and to create awareness.
When my mom found the ACM Lifting Lives
Music Camp, I couldn’t wait to go. I love
country music, and I wanted to help with
research on Williams syndrome.The country
stars give their time to work with us.They
make me feel valued and respected, and they
shine a light on our abilities.
Juan José and Ana Cardona
Parents
We are so thankful to be part of research.
When our daughter started JEEP [Joint
Attention, Enhanced MilieuTeaching, and
Expanding Play], she was not talking, or
playing.This project made a huge impact on
her life and so ours as well. After a few
months, she started saying some words and
playing. We were so amazed of the
improvement she had.
Tammy Vice
Songwriter, Parent, Advocate
Each of us has a role to play in life for which
we are uniquely made. It has been sweet for
me to help create songs for SENSETheatre,
but my favorite part is seeing what develops
behind the scenes. Social growth happens
when the kids begin to understand the
importance of supporting each other. And
hearing my daughter Morgan say, “I’m in the
show!” and knowing that it’s true.
Megan Hart
Advocate
Self-advocacy is an important part of my life. I
have been able to obtain education, pursue a
career, and live a meaningful life based on my
decisions and persistence. It is a disservice
when the voices of others overpower the
needs, desires, and goals that individuals with
disabilities have for themselves.This is why
Tennessee Allies in Self-Advocacy (TASA) is so
important.
It is reassuring to know some-
body or something is there just
in case life gets the best of
some of us sometimes. Just
knowing this has helped me
today and for this I am thankful.
—Caller toTennessee Disability
Pathfinder Helpline
4 Winter 2013 | DISCOVERY
5. (1) Understanding Genetic Syndromes
Elisabeth Dykens, Ph.D. (Psychology,
Psychiatry, Pediatrics) My father was a
psychiatrist, and I grew up accustomed to
being with people with disabilities. During
my graduate training, I worked directly
with children with genetic syndromes and
autism. These experiences started me on the
path to looking at genetic syndromes as a
window for understanding connections
among genes, brain, and behavior and ways
to optimize interventions. We look for
strengths to develop as well as difficulties to
remediate, and for ways to promote well-
being.
(2) Promoting Language Development
Paul Yoder, Ph.D. (Special Education)
As a sophomore volunteer in a preschool for
children with language impairments, I was
fascinated by these bright children who had
difficulty communicating. Doing
developmental disabilities research
combines my love of the scientific method,
my desire to be a positive force in the lives
of children with communication disabilities,
and my passion for learning. Our lab works
to understand the match needed between
language and communication therapy
methods and the strengths and weaknesses
that different children bring to therapy.
(3) Treating Sleep Disorders
Beth Malow, M.D., M.S. (Neurology,
Pediatrics) As a sleep researcher and parent
of sons on the autism spectrum, I realized
that identifying and treating disordered sleep
in autism, Down syndrome, and other
developmental disorders could make a huge
difference in the lives of children and families.
My team focuses on improving methods for
studying and treating sleep disorders. As
director of the Vanderbilt Autism Treatment
Network site, we collaborate with the other
ATN sites to improve medical care.
(4) Improving Autism Diagnosis and
Treatment • Zachary Warren, Ph.D.
(Pediatrics, Psychiatry, Special
Education) My clinical, research, and
training interests revolve around improving
systems of care for individuals with autism
and their families, especially improving early
identification and intervention.
Unfortunately, the process of developing
initial concerns, discussing concerns with
providers, obtaining accurate diagnosis, and
translating this information into effective
treatment remains a complex, distressful one
for most families. Families often must wait
long periods of time to find out answers to
questions they are desperate to know about.
In my opinion, this process can and should
be dramatically improved.
I spent most of my graduate training
learning about the development of very
young children who had experienced serious
life stressors. This focus on early social and
emotional development was matched with
opportunities to work with young children
with autism during my fellowship. Since
then, I have worked with young families
concerned that their child may have autism.
It is a challenging and powerful experience
to try to provide families with answers.
I am working on projects that study
infants at high risk for autism in hopes of
developing methods for earliest detection,
which early behavioral intervention
programs work best for specific children,
as well as training programs for building
system capacity for early accurate diagnosis
and effective treatment for families in their
own backyards.
WHY SCIENTISTS STUDY BEHAVIOR CHANGE
1
2 4
3
s
C
DISCOVERY | Winter 2013 5
6. (1) Investigating Related Gene
Disorders • Sarika Peters, Ph.D.
(Pediatrics) I study two related single gene
disorders, Rett Syndrome, which primarily
affects girls, and MECP2 duplication
syndrome, a similar syndrome that affects
boys. My role is to better define what clinical
concerns “look like” in these syndromes, in
order to design more targeted interventions
and supports to help improve quality of life.
We also seek out non-invasive approaches
(e.g., saliva, psychophysiology) for linking
underlying biology to these behaviors. My
interactions with families inspire my work.
(2) Exploring Neurodevelopment and
Neurodegeneration • Aaron Bowman,
Ph.D. (Neurology and Pediatrics) I am
fascinated by the connections between
neurodevelopment and neurodegeneration.
My research focuses on degenerative processes
affecting the basal ganglia, a brain structure
necessary to control movement. We use both
basic research models as well as new methods
that convert human skin cells into
personalized models of neurological disease
and environmental health. By learning how
genes and environment interact and influence
the development and maintenance of brain
function, we hope to mitigate environmental
risk factors of disorders and improve long-
term health.
(3) Studying Cognitive Impairment
Tricia Thornton-Wells, Ph.D. (Molecular
Physiology & Biophysics) I have long
been fascinated with brain disorders, but my
family history of Alzheimer disease (AD) has
influenced my study of cognitive impairment.
Why do some family members develop AD
and others do not? What happens in the
brain 10 to 20 years before a person shows
signs of dementia? What can we do to prevent
or postpone onset? Over half of persons with
Down syndrome develop dementia by age 50.
By studying AD in Down syndrome as well as
in persons with typical neurodevelopment, we
aim to advance neuroimaging, genetic
profiling, and therapeutic targets.
(4-5) Finding Pathways to New
Treatments • Jeremy Veenstra-
VanderWeele, M.D. (Psychiatry,
Pediatrics, and Pharmacology) My
research focuses primarily on genetic mouse
models of autism susceptibility, with the goal
of understanding the changes in the brain
that lead to altered social communication and
repetitive behavior in autism spectrum
disorder (ASD). In parallel, our research
group is testing new treatments based upon
published findings in genetic mouse models
of autism, including potential treatments in
individuals with fragile X syndrome and in
individuals with ASD without a known cause.
I grew up knowing that the son of a close
family friend had autism. I came to
empathize with this family’s experience.
This primed me for working in the lab of
Dr. Ed Cook, a child psychiatrist launching a
genetics lab, who encouraged his students also
to see patients. As a result of these experiences
and my own clinical work as a child
psychiatrist, I find myself pulled to
understand why social communication that
feels so natural to some can be so unnatural
for others. Seeing children who seem stuck
in repetitive patterns of behavior makes me
wonder what in the brain is causing this
persistent behavioral “hiccup.” Mouse models
of autism susceptibility offer a path to
understanding how brain development and
function are altered, with the hope that this
path will lead to new treatments.
WHY SCIENTISTS STUDY NEURODEVELOPMENTAL DISORDERS
WHY
WHY
3
1
2 4 5
6 Winter 2013 | DISCOVERY
7. PATHWAY
(1) Unraveling the Mysteries of Reading
Laurie Cutting, Ph.D. (Special
Education, Psychology, Radiology &
Radiological Sciences, Pediatrics)
When I worked in the classroom, one young
boy had all the resources one could imagine
but could not learn to read. From then on,
I wanted to understand what was happening
in the brain when children were experiencing
reading difficulties. In my lab, we’re trying to
unravel the mysteries of how people
comprehend well and what happens when
they don’t. We focus on which elements are
most important, e.g., vocabulary,
understanding grammar, structures of text,
type of text, and how these relate to different
brain systems.
(2) Connecting Preschool and Literacy
David K. Dickinson, Ph.D. (Teaching &
Learning) I’m seeking to understand features
of preschool classrooms that foster language
and literacy development and to describe the
interplay between language and print-based
knowledge. I’m especially interested in
language development, because many
children who struggle with reading lack the
academic language skills required for the later
elementary grades. I am developing an
intervention in which teachers are coached in
methods of teaching vocabulary through
book reading and guiding children in book-
connected play.
(3) Improving Lives of Youth with
Significant Disabilities • Erik Carter,
Ph.D. (Special Education) Young people
with significant disabilities have wonderful
strengths, aspirations, and friendships to
share. Yet far too many people never have the
opportunity to know these essential members
of their communities. My research focuses on
identifying ways that schools, workplaces,
neighborhoods, and congregations might
welcome and support people with disabilities
and their families to participate more fully in
community life. A recurring theme is that
schools and communities that commit to
inclusion find they are strengthened.
(4) Matching Instruction to Individual
Learner Needs • Doug Fuchs, Ph.D.,
and Lynn Fuchs, Ph.D. (Special
Education) We develop assessment and
instructional methods to increase academic
achievement of students with learning
disabilities (reading and math), as well as of
high-, average-, and low-achieving students
without disabilities. To test the efficacy of
these
instructional
methods, we
conduct
large-scale, school-based randomized control
trials. We work closely with hundreds of
teachers and administrators in school systems
in Tennessee and in other states. We also
develop “differentiated” instruction (e.g.,
small group tutoring procedures) for children
chronically unresponsive to the core reading
and math instructional programs. In this
regard, we are exploring how child
characteristics moderate the efficacy of various
instructional methods. Our goal is to
understand how to match instruction to
individual learner needs. Our collaboration
with researchers in the VKC
Psychophysiology Lab and the Vanderbilt
Institute of Imaging Science has broadened
our understanding of learning disabilities in
important ways.
Each of us began our careers as general
education classroom teachers, where we
struggled to address the needs of
students with learning disabilities.
This motivated us to work hard
over the years to provide general
and special education teachers
with methods that can help
them address the needs of
these students more
effectively.
WHY SCIENTISTS STUDY EDUCATIONAL CHANGE
3
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DISCOVERY | Winter 2013 7
8. PATHWAY
WHY SCIENTISTS STUDY MENTAL HEALTH
(1) Understanding Brain Development
Randy Blakely, Ph.D. (Pharmacology
and Psychiatry) To figure out how genetic
and environmental factors interact to support
typical brain development, scientists must
understand how the brain works across many
levels. I study neurotransmitter transporters,
proteins involved in transmitting electrical
signals through the brain. Transporter
proteins are targets for therapeutic drugs, as
well as drugs of abuse. We use our
understanding of these proteins to develop
animal models of autism, ADHD, and
depression. We keep our eye on how our
findings could lead to new therapies.
(2) Identifying the Neurobiology of
Temperament • Jennifer Blackford,
Ph.D. (Psychiatry) Individual differences
in temperament—how we think, feel, and
act—can either confer risk or provide
protection from psychiatric disorders like
anxiety and depression. My lab studies the
neurobiological basis of these individual
differences, using modern neuroscience
methods such as neuroimaging and genetics.
Our goal is to determine how differences in
genetic variability and brain alterations may
confer risk or protection. Understanding the
links between neurobiology and psychiatric
disorders can inspire the development of
novel preventions and interventions in high-
risk individuals.
(3) Coping with Stress • Bruce
Compas, Ph.D. (Psychology and
Pediatrics) My research involves observing
the effects of stress on physical health and
psychopathology, and processes of coping
and self-regulation in response to stress and
adversity in children, adolescents, and adults.
Out of this comes the development of
interventions to enhance the ways that
individuals and families cope with stress. My
current work is focused on the psychological
and biological processes of stress on children,
adolescents, and families coping with cancer,
chronic pain, or depression.
(4-5) Understanding Cognition and
Social Function • Sohee Park, Ph.D.,
(Psychology and Psychiatry) As a child
growing up in Seoul, I planned to be an
anthropologist because I was fascinated by
how seemingly unfathomable surface cultural
differences could be bridged inside. After a
detour into physics and four countries later, I
am still trying to solve the puzzle of the ‘other’
but in the context of severe mental illness.
My lab focuses on understanding the
neural bases of schizophrenia, bipolar
disorder, and related conditions, while
always being mindful of the subjective
experiences of the people whose lives are
disrupted by psychosis. We believe that
disturbed sensory and perceptual processing
in the brain cascades into anomalous
cognitive and social functioning in these
conditions, and that training the brain to
process incoming information more
efficiently could lead to improvements in
cognition and outcome. Such interventions
are more effective if they begin early, for
example, during adolescence, because this is
the period during which the behavioral
signs of psychosis emerge.
Our goal for the next decade is to
develop noninvasive and effective
interventions that are firmly grounded in
psychology and neuroscience. To reach that
goal, we are collaborating with other VKC
investigators, including Bruce Compas,
Nilanjan Sarkar, Tricia Thornton-Wells, and
Adam Anderson.
5
WHY?
WHY?
CLINICIANS
STUDENTS
TRAINEES
PATHWAY
8 Winter 2013 | DISCOVERY
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9. DISCOVERY | Winter 2013 9
Connecting With Public Policy Makers •
Elise McMillan, J.D., VKC UCEDD
Co-Director Why do we work to connect
research, training, and service models to
developmental disabilities public policy? We
hear this question over and over again about
connecting evidence-based practices with
work in our schools and communities.
The VKC University Center for Excellence
offers a wonderful opportunity to make those
connections. One of our charges is to inform
policy makers about best practices.
We do that on the local level through
participation in activities like the Mayor's
Advisory Council on Exceptional Education,
at the state level through projects like
TennesseeWorks and the Employment
Systems Change Grant, and at the federal
level as we take part in national disability
organizations.
This happens through testimony, shared
articles, and professional development in areas
of autism, Down syndrome, and other
genetic syndromes. We are a vehicle for
sharing research findings and recommended
practices with public policy makers at the
local, state, and national levels.
When the Tennessee Legislature was
developing policies about insurance coverage
for autism treatment, they turned to the
VKC. When expertise is needed to conduct
statewide needs assessments, VKC UCEDD
faculty and trainees are there, using research
tools like REDCap developed at Vanderbilt.
With the support of university students
and faculty, we have collected family stories
and shared with public policy makers, so they
will understand how disabilities affect the
citizens they represent.
And the work continues.
SENSE Theatre—A Unique Autism
“Lab” • Blythe Corbett, Ph.D.
(Psychiatry), SENSE Theatre Founder
and Director Most people think of theatre as
a home for creative actors who were magically
born for the stage. I think of theatre as an
engaging environment in which to teach
social communication. SENSE Theatre
Camp, an intervention for children and youth
with autism, has three components: peers,
play, and performance. The typically
developing peers are young actors
conceptualized as developing “experts” on
social communication, flexible thinking, and
empathy–all areas of challenge in autism.
With supervision, they engage the SENSE
campers using theatre games, improvisation,
and play rehearsal, which culminates in
public performances.
Most of our SENSE campers are evaluated
before and after the camp to identify changes
in functioning. The research allows us to test
the intervention, refine it, and eventually to
determine the best responders.
Since our program is peer-mediated, we
train the typically developing youth. We teach
camp counselors who are the next generation
of psychologists, educators, and scientists.
Whether working on the stage with our
campers or behind the scenes collecting data,
students experience applied research.
SENSE Theatre is among the more unique
lab experiences students may have and one of
the most profound for understanding the
extraordinary gifts and challenges of autism.
Prader-Willi
Syndrome—Piecing
the Big Picture •
Elizabeth Roof, M.A.,
Senior Research
Specialist Although
I trained and worked
as a clinician, in 1995,
I became research
coordinator for a multi-year study of Prader-
Willi syndrome (PWS). After a few short
months, I was hooked. The people who
enrolled came for 3 days. I learned to listen,
to read body and vocal cues, and to anticipate
problems. Their parents accompanied us
throughout the 20 assorted physical and
psychological assessments. I heard their stories
of the struggles and joys of living with a child
with special needs.
I could fully listen to what families needed
with some ability and resources to make a
difference. The more data we collected, the
more I could see the big picture: when
behavior problems emerged, what periods
were critical for intervention, when helping
with IEP/vocational and residential
placements made the biggest difference in
behavior and learning. Now in research led by
Elisabeth Dykens, we are focusing on
behavior and psychiatric
issues.
Over the years, we have
trained students. Some have
gone on to study PWS in
their own labs. Others have
studied how PWS may be
related to autism and other
developmental disorders.
We have a trusting
relationship with families, which allows us to
collect amazing data that can truly change
lives. I wanted to make a difference. I get to
do it every day.
WHY INTEGRATE SERVICES, RESEARCH,
TRAINING, AND PUBLIC POLICY
10. PATHWAY
WHY GRADUATE STUDENTS AND POSTDOCS ROCK!
The Rock Stars of Science (Rock S.O.S.)
national campaign (see p. 3) encouraged
youth to pursue careers in science. As a
Eunice Kennedy Shriver Intellectual and
Developmental Disabilities Research
Center, the VKC plays a leadership role in
training predoctoral and postdoctoral
investigators in intellectual and
developmental disabilities (IDD) research.
Below we highlight a few. All our
predoctoral students and postdoctoral
fellows are the Future Rock Stars of IDD
Science!
(1) Courtney Wright, Doctoral Student
in Special Education, Kaiser KidTalk
Projects Coming from speech pathology,
I knew about development and assessment,
but not much about how to help young
children and their families. Now I have
learned a number of evidence-based
practices for teaching a variety of skills to
young children with disabilities. I feel
confident within my clinical work and my
ability to include and teach families
strategies to use in their everyday lives. I look
forward to passing these newly acquired skills
on to future practitioners.
(2) Qiuyun Fan, Doctoral Student in
Biomedical Engineering, Cutting Lab
I study the neurocorrelates of reading ability
in the brain using magnetic resonance
imaging. I am developing new imaging and
analysis techniques to study how neural
tissues are organized in the brain, and how
brain regions with distinct functions
collaborate to underpin complex cognitive
behavior. At the VKC, I have unique
opportunities to take advantage of this
platform where engineers, psychologists,
pediatricians, educators, clinicians, and others
brainstorm ideas, so that
interdisciplinary questions
can be addressed and
the frontiers of science
pushed forward.
(3) Marc Mergy,
Doctoral Student
in Neuroscience
Graduate Program,
Blakely Lab I chose
neuroscience research
because the brain and
many brain disorders
remain an elusive
"black box." There is
plenty left to learn!
My own work focuses
on a new mouse model
of ADHD that I have
used to further our
understanding of the
molecular mechanisms
underlying this disorder.
It's a great feeling to
know that my work has
developed a useful tool
for future research.
(Above) Christopher Muller, Doctoral
Student in Neuroscience Graduate
Program, Veenstra-VanderWeele Lab
Earlier, I worked in a human genetics
laboratory involved in collecting DNA
samples from families with a history of
autism. Although I enjoyed it, I was
frustrated that I could not do more for
families. I searched for neuroscience
graduate programs with strength in
translational autism research, which led me
to Vanderbilt, where I am doing research in
a lab developing and characterizing novel
animal models of autism. If my work can
somehow someday help a family affected by
autism, it will be worth the struggle.
10 Winter 2013 | DISCOVERY
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11. The Vanderbilt LEND is part of a
national network of Leadership
Education in Neurodevelopmental
Disabilities (LEND) programs. Their goal is
to improve the health of infants, children,
and adolescents with neurodevelopmental
and related disabilities through leadership
training. The Vanderbilt LEND prepares
graduate and postgraduate students in
13 health-related fields, and provides
specialized training in autism and pediatric
audiology.
The VKC University Center for
Excellence in Developmental Disabilities
(UCEDD), also part of a national network,
trains university students, practicing
professionals and direct care providers,
individuals with disabilities and family
members, disability advocates and policy
makers.
Below we highlight a few LEND and
UCEDD trainees. Collectively, VKC
LEND and UCEDD trainees are future
educators, researchers, clinicians, service
providers, and advocates.
(1) Cong Van Tran, 2011-12 TRIAD
and LEND Psychology Trainee The
VKC has rich resources—experts, seminars,
training, tools, tests, facilities—that
facilitated my learning. Most important was
developing professional and personal
relationships with psychologists and autism
and disability specialists. Now I’m doing
disability training in my home country of
Viet Nam.
(2) Kelsey Bush, 2012-13 UCEDD
Cognitive Studies and Human &
Organization Development Trainee
I knew from a young age that I wanted to
work with individuals with intellectual and
developmental disabilities. I’ve learned that
even small acts can have huge ripple effects.
I have had amazing opportunities working
in the Prader-Willi syndrome project and in
VKC Communications. These experiences
showed me different ways in which I could
contribute to the field.
(3) Hilary Davis, 2011-12 LEND
Pediatric Audiology Trainee Last week, I
had a 4-year-old light up with excitement
and high-five me once he got his new
hearing aid—he was hearing things he had
never heard before! I work in schools,
teaching about hearing loss and how to
improve classroom settings. These moments
remind me that I am passionate about kids
and their success.
(4) Matthew Brock, 2012-2013
UCEDD Special Education Trainee
There is an enormous gap between
evidence-based practices and the reality of
day-to-day special education practice. I get
excited every time I am able to help a
teacher or paraprofessional use a new
intervention strategy effectively, and then
measure (and celebrate with them) the
difference that it makes for a student with a
disability.
(5) Carrie Spero, 2012-2013 LEND
and UCEDD Social Work Trainee As a
UCEDD trainee, I have worked with Next
Steps students and others and increased my
knowledge of disabilities. Through LEND,
I have seen the influential power that
individuals, teams, and communities can
have in working toward change. I feel more
confident every day in my ability to serve
the community.
WHY LEND AND UCEDD TRAINEES ROCK!
PATH
4
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2
3
5
DISCOVERY | Winter 2013 11
13. The ART of AUTISM showcases the artistic gifts of individuals with autism. April-July, the VKC is exhibiting work by participating artists from Tennessee and neighboring states.
CALENDAR OF EVENTS | APRIL–JULY 2013
DERRICKFREEMAN
JALYNWESTON
SARAHE.VAUGHN
SAMMOSES
APRIL 3*
Developmental Disabilities
Grand Rounds
Big Strokes in Little People:
Biology and Clinical Considerations
BethAnn McLaughlin**, Ph.D.
Assistant Professor of Neurology
Lori Jordan**, Ph.D., Assistant
Professor of Neurology. Register at
kc.vanderbilt.edu/registration
Wednesday 12 p.m.
APRIL 5-6
Fifth Annual Tennessee
Adult Brothers and Sisters
(TABS) Conference
Sibling keynote speakers:
(Fri) Scott Modell, Ph.D., Deputy
Commissioner of Policy &
Innovation, TN Dept of Intellectual
& Developmental Disabilities;
(Sat) Nancy Webster, President
of The Arc. For adults who have a
sibling with a disability, siblings-in-
law, cousins, professionals
interested in sibling issues. $50 ($25
students) includes meals. Register
at kc.vanderbilt.edu/registration
Contact info.tabs@vanderbilt.edu
Holiday Inn Nashville-Vanderbilt,
2613 West End Avenue
Friday 12-7:30 p.m.
Saturday 8:30 a.m.-1:30 p.m.
APRIL 10
Neuroscience Graduate
Program Seminar Series
Epigenetics at the Interface of
Genetics and Environment in Autism
Janine LaSalle, Ph.D.
Professor of Medical Microbiology
and Immunology, University of
California Davis. Co-sponsor
Vanderbilt Brain Institute
208 Light Hall
Wednesday 4:10 p.m.
APRIL 11*
Augmentative and
Alternative Communication
(AAC) Presentation
Assistive Technology for
Students With Disabilities:
The Legal Ins and Outs
Erin Richardson, Co-Director for
Advocacy, Special Education
Advocacy Center. Free and open
to the public. Register at
kc.vanderbilt.edu/registration
Thursday 6:30-8 p.m.
APRIL 12*
Augmentative and
Alternative Communication
(AAC) All-Day Workshop
AAC Assessment: Making the Match
Karen Casey, M.A., CCC-SLP
$175 professionals, $50 students
$125 group rate for 2 or more from
same agency/school. Register by
April 5 at kc.vanderbilt.edu/
registration. Friday 8 a.m.-3:30 p.m.
APRIL 13*
SibSaturday
For siblings 5-7 and 8-13 years who
have a brother/sister with a disability
Games, friends, conversation
$10/child, $20 max/family
(assistance available). Register at
kc.vanderbilt.edu/registration
(required in advance)
Info (615) 936-8852 or
laurie.fleming@vanderbilt.edu
Saturday 10 a.m.-2 p.m.
APRIL 20*
TRIAD Families First Workshops
Developing Basic Communication
Register at kc.vanderbilt.edu/
registration. Info (615) 322-6027 or
families.first@vanderbilt.edu
Saturday 9 a.m.-12 p.m.
See website for Summer workshops
MAY 2-3
Phonological
Awareness Workshop
Melanie Schuele**, Ph.D.,
CCC-SLP, Associate Professor of
Hearing & Speech Sciences
For general and special education
teachers, speech-language
pathologists, reading specialists.
Parents welcome. 1-day $70 (.65
ASHA CEUs), 2 days $120 (1.3
ASHA CEUs) Register at
kc.vanderbilt.edu/registration. Info
languagelab@vanderbilt.edu
8th Flr Lecture Hall, Vanderbilt
Bill Wilkerson Center, Medical
Center East. Thursday-Friday
8:30 a.m.-4:15 p.m.
MAY 17
Next Steps at Vanderbilt
Open House
Info (615) 322-5658. Register at
kc.vanderbilt.edu/registration
Friday 2-4 p.m.
MAY 30-31
11th Annual Tennessee Disability
MegaConference
Deep Roots, Broad Branches, and
Strong Wings
World-class speakers, interactive
workshops, educational sessions,
exhibits. Info at
www.tndisabilitymegaconference.org
(includes breakfast/lunch)
$105 one day (Thursday or Friday)
$195 for 2 days (Thursdays-Friday)
Nashville Airport Marriott,
600 Marriott Dr (615-889-9300)
Unless otherwise noted,
events are free and open to
the public. Events are subject
to change. Please check the
website calendar at
kc.vanderbilt.edu or contact
(615) 322-8240 or toll-free
(1-866) 936-VUKC [8852].
Please keep this calendar
and check the Event
Calendar on the VKC
website for updates. If you
wish to receive event
announcements by email,
send your email address to
kc@vanderbilt.edu.
For disability-related
training and other events
statewide and nationally,
see the searchable Pathfinder
Disability Calendar
www.familypathfinder.org.
*Event will be held in Room
241 Vanderbilt Kennedy
Center/One Magnolia Circle
Bldg (110 Magnolia Circle).
**VKC Member or Investigator
DISCOVERY | Winter 2013
14. CALENDAR OF EVENTS | APRIL–JULY 2013
JUNE 5
Neuroscience Graduate
Program Seminar Series
Using Music to Change the Way the
Brain Processes Language
Aniruddh D. Patel, Ph.D.
Senior Fellow in Theoretical
Neurobiology, Esther J. Burnham
Senior Fellow, Neurosciences
Institutes, LaJolla, CA
Co-sponsor Vanderbilt Brain Institute
Room 1220 MRB III Lecture Hall
Wednesday 4:10 p.m.
JUNE 14*
Community Advisory
Council Meeting
Info (615) 936-8852
Friday 9 a.m.-2 p.m.
JUNE 25-26*
Autism Diagnostic
Observation Schedule (ADOS-2)
Clinical Training
TRIAD workshop for psychologists,
pediatricians, behavioral specialists,
and SLPs. Fee: $300. Register at
kc.vanderbilt.edu/registration. Info
amy.r.swanson@vanderbilt.edu,
(615) 322-6533. Tuesday-
Wednesday 8 a.m.-4:30 p.m.
JUNE 29*
Clinical Genetics for
Health Care Professionals
Workshop by Vanderbilt Pediatrics
Developmental Medicine Division for
health care professionals who are
not geneticists. $50 (includes lunch)
7 CME & APA CE. Register at
kc.vanderbilt.edu/registration
Info pam.grau@vanderbilt.edu,
Saturday 8 a.m.-2 p.m.
JULY 30-31*
School Speech-Language
Pathology Conference
Two lunch-time plenary sessions
and selection among 6 (90-minute)
small group sessions (1.1 ASHA
CEUs) Register at
kc.vanderbilt.edu/registration
Info languagelab@vanderbilt.edu
Tuesday-Wednesday
8:30 a.m.-3 p.m.
VKC SUMMER
PROGRAMS
Info laura.mcleod@vanderbilt.edu
G
Registration is closed. Contact TN
Disability Pathfinder for information
on summer activities.
• JUNE 3-15
SENSE Theatre CampG
For youth, 7-18 years of age,
with and without autism
spectrum disorders
• JUNE 23-29
ACM Lifting Lives Music CampG
Residential camp for individuals
with Williams syndrome (16 yrs+)
• JULY 14-19
Next Steps at Vanderbilt Summer
Institute. Residential college
transition program for rising high
school juniors, seniors, and
young adults with developmental
disabilities up to age 24
READING CLINIC
SUMMER SESSION
• JUNE 3-JULY 15
(no sessions Wk July 4)
Tutoring students through middle
school. 24 (40-minute) sessions,
ranging 8 a.m.-12 noon
Monday-Thursday
Space limited. Apply early.
Contact (615) 936-5118,
readingclinic@vanderbilt.edu
ARTS AND DISABILITIES
EXHIBIT
Monday-Friday 7:30 a.m.-5:30 p.m.
Lobby VKC/One Magnolia Circle
Bldg. Info (615) 936-8852
• APRIL THROUGH JULY
ART of AUTISM
AUTISM TRAININGS FOR
K-12 SCHOOL PERSONNEL
With the Tennessee Department
of Education, TRIAD offers free
autism-specific workshops for
school personnel, parents, and the
community in locations across the
state. Dates/locations TBA; see
kc.vanderbilt.edu/TRIAD/events.
LEARNING
ASSESSMENT CLINIC
Multidisciplinary academic assess-
ments of students, 5-25 years,
to identify learning strengths and
challenges and to recommend
strategies to improve academic
learning. Info (615) 936-5118
NEXT STEPS AT
VANDERBILT
A 2-year certification postsecondary
education program for students
with intellectual disabilities providing
individualized Programs of Study
in education, social skills, and
vocational training. Info (615) 322-
5658 or NextSteps@vanderbilt.edu
TAKE PART IN RESEARCH
VKC Research Studies
For children and adults, with and
without disabilities
Lynnette Henderson (615) 936-0448
Toll-free (1-866) 936-VUKC [8852]
• Research Family Partners
kc.vanderbilt.edu/rfp
Register and be notified of
research studies
• StudyFinder
kc.vanderbilt.edu/studyfinder
View lists of studies, criteria,
and contact information
• See also VUMC Clinical Trials
www.vanderbilthealth.com/
clinicaltrials
TENNESSEE DISABILITY
PATHFINDER MULTI-
CULTURAL OUTREACH
Helpline; Web site with Searchable
Database, Calendar, and Resource
Library; Print Resources
www.familypathfinder.org
English (615) 322-8529
Español (615) 479-9568
Toll-free (1-800) 640-INFO [4636]
tnpathfinder@vanderbilt.edu
Project of VKC UCEDD and TN
Council on Developmental
Disabilities
TENNESSEE WORKS
Web hub for information related
to employment of people with
disabilities
TennesseeWorks.org
(615) 936-0448
Winter 2013 | DISCOVERY
Next Steps at Vanderbilt Summer Institute, a postsecondary education preparatory
program, is accepting applications for its July 14-19 on-campus program.