The digestive system breaks down food into nutrients that the body can use. It begins with the mouth and ends with the anus. Major organs include the mouth, esophagus, stomach, small intestine, large intestine, liver, gallbladder and pancreas. Food is ingested, digested, absorbed in the small intestine, and waste is excreted. Digestion involves breaking down food into smaller molecules like amino acids and monosaccharides using enzymes from the saliva, stomach acid, bile, and pancreatic juice. The small intestine absorbs nutrients into the bloodstream through villi while the large intestine absorbs water before excreting waste.