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This document discusses different types of polysaccharides. It first describes homopolysaccharides which are either used for storage like starch, glycogen, dextrin, and inulin or are structural like cellulose and chitin. It then discusses heteropolysaccharides called muco polysaccharides or GAGs which include hyaluronic acid, chondroitin sulfate, heparin, and keratan sulfate. It provides details about dextran, noting that it is a highly branched homopolymer of glucose with different linkages, produced by microorganisms, with a high molecular weight between 1-4 million. Dextran is highly inert and used in gel preparation and as an intravenous plasma volume expander
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- 1. POLYSACCHARIDES Homopolysaccharides Storage homopolysa ccharides Structural homopolysa ccharides v Starch v Glycogen v Dextrin v Glycogen v Inulin v Cellulose v Chitin Heteropolysaccharides Muco polysaccharides or GAG’s v Hyaluronic acid v Chondroitin sulfate v Heparin v Keratan sulfate
- 2. DEXTRAN vThese are highly branched homopolymers of glucose units with 1-6,1- 4, and 1-3 linkages vThese are produced by micro organisms vThey have molecular weight 1 million to 4 millions vThey are highly inert vUsed in preparation of gels in SDS-PAGE vIt is often administered through intravenous infusion as plasma volume expander in the treatment of hypovolemic shock
- 3. DEXTROSE, DEXTRIN AND DEXTRAN ARE DIFFERENT DEXTROSE D-glucose is otherwise called DEXTROSE, a term often used in bed-side medicine, eg:dextrose drip DEXTRIN It is the partially digested product of starch DEXTRAN It is high molecular weight carbohydrate, synthesized by bacteria