en este presentacion encontraran una breve descripcion del microorganismo ya mencionado , adema de las enfermedades causadas y las principales formas diagnosticas
en este presentacion encontraran una breve descripcion del microorganismo ya mencionado , adema de las enfermedades causadas y las principales formas diagnosticas
Llamadas tiñas de manera común, las dermatofitosis son un conjunto de micosis superficiales que afectan la piel y sus anexos (uñas y pelos), causadas por un grupo de hongos parásitos de la queratina denominados dermatofitos y que de manera excepcional, invaden tejidos profundos.
Son infecciones de los tejidos queratinizados (piel, pelos y uñas) causadas por un grupo de hongos queratinofílicos denominados dermatofitos.
Presentación sobre la esporotricosis. Micosis subcutánea más frecuente en América Latina. Definición, agente etiológico, epidemiología, formas de presentación (cuadro clínico), diagnóstico, tratamiento.
Presentación sobre dermatofitos o dermatofitosis, también llamadas tiñas. Se abordan: tiña capitis (de la cabeza), tiña del cuerpo (tiña corporis), tiña pedia (del pie), tiña de las uñas (onicomicosis), tinea manum (tiña de las manos), tinea cruris (tiña inguinal). Definición, epidemiología, fisiopatología, nueva clasificación de los dermatofitos, agentes etiológicos, diagnóstico y tratamiento.
Llamadas tiñas de manera común, las dermatofitosis son un conjunto de micosis superficiales que afectan la piel y sus anexos (uñas y pelos), causadas por un grupo de hongos parásitos de la queratina denominados dermatofitos y que de manera excepcional, invaden tejidos profundos.
Son infecciones de los tejidos queratinizados (piel, pelos y uñas) causadas por un grupo de hongos queratinofílicos denominados dermatofitos.
Presentación sobre la esporotricosis. Micosis subcutánea más frecuente en América Latina. Definición, agente etiológico, epidemiología, formas de presentación (cuadro clínico), diagnóstico, tratamiento.
Presentación sobre dermatofitos o dermatofitosis, también llamadas tiñas. Se abordan: tiña capitis (de la cabeza), tiña del cuerpo (tiña corporis), tiña pedia (del pie), tiña de las uñas (onicomicosis), tinea manum (tiña de las manos), tinea cruris (tiña inguinal). Definición, epidemiología, fisiopatología, nueva clasificación de los dermatofitos, agentes etiológicos, diagnóstico y tratamiento.
Fungal skin infections are commonly affect the outer layer of the skin, nails and hair. Most of the fungi causing infections are usually dermatophytes (tinea), yeast (candida) and molds
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Astronomy Update- Curiosity’s exploration of Mars _ Local Briefs _ leadertele...
Dermatofitosis
1. Dermatofitosis
Hernández Navarro Ney Lee
Salazar Virgen Alex Enrique
Universidad Autónoma de Nayarit
UNIDAD ACADÉMICA DE MEDICINA
Microbiología, parasitología y micología médica
2 “D”
2. Dermatofitosis
La dermatofitosis, conocida también como tiña,
es una infección por hongos crónica de la piel, el
cabello o las uñas.
➔ Causadas por diversos hongos diferentes
➔ Son de las micosis superficiales que
comúnmente afectan al humano
Los romanos le llamaron “tinea” por la semejanza
con pequeñas larvas de insectos.
Antes había cuatro géneros de dermatofitos:
quitaron el género “Achorion”
1
3. Clasificación (agentes etiológicos)
Los tres géneros que conforman
este grupo son:
● Trichophyton
● Microsporum
● Epidermophyton
Tres grupos ecológicos clasificados:
Estos 3 géneros se llaman dermatofitos.
● Antropofílicos
● Zoofílicos
● Geofílicos
Antropo = Humano
Zoo = Animal
Geo = Tierra /suelo
Filia = Atracción
2
4. Los dermatofitos antropofílicos son
aquellas especies que primariamente
parasitan el tejido humano.
● T. rubrum
● T. tonsurans
● T. mentagrophytes var interdigitale
● T. violaceum
● T. schoenleinii
● M. audouinii
● E. floccosum. Los dermatofitos zoofílicos son
aquellos que tienen afinidad por
el tejido queratinizado de una
gran variedad de aves y
mamíferos que actúan como
hospederos.
● M. canis
● T. verrucosum
● T. equinum
● T. gallinae
Los dermatofitos geofílicos
son los que habitan en el suelo
● M. gypseum
● M. fulvum.
Tinea unguium causado por T. rubrum
Tinea capitis causado por M.
canis
Tinea corporis causado por
Microsporum gypseum
3
5. Características generales de los dermatofitos
Trichophyton:
● Sus colonias tienen el aspecto de la cera, son
planas o algodonosas.
● Son mohos caracterizados por el desarrollo de
macro y microconidios de paredes lisas.
● Causan la tiña, incluido el pie de atleta, la tiña
inguinal y las infecciones similares de las uñas,
la barba, la piel y el cuero cabelludo.
4
6. Características generales de los dermatofitos
Microsporum:
● Presenta colonias algodonosas o pulverulentas,
de color blanco o parduzco.
● Macroconidias (40-150 x 8-15 µ m)
● Las microconidias son piriformes, pero pueden
faltar, y el tamaño oscila entre 2,5-3,5 x 4-7 µ m.
● Son también frecuentes el micelio en raqueta, las
hifas pectíneas, los órganos nodulares y las
clamidosporas.
● Causantes de la tiña de la cabeza, tiña corporis.
5
7. Características generales de los dermatofitos
Epidermophyton:
● Hongo filamentoso, presenta abundantes
macroconidios en racimos, con pared gruesa y
lisa y con extremos romos, divididos con 2-4
septos.
● Sin microconidios.
● En cultivos viejos aparece con hifas en forma
de raqueta y clamidosporas.
● Sin embargo, macroscópicamente las colonias
son aterciopeladas y amarillentas con un
aspecto pulverulento y plano
6
9. Factores de virulencia
This can be the part of the presentation where
you introduce yourself, write your email…
8
10. Patogenia
Para el desarrollo de un proceso infeccioso es
necesario: una cantidad mínima de esporas.
● Se produce una reacción inflamatoria tipo
tuberculina.
● Durante la reacción inflamatoria se liberan
citotoxinas.
● Como consecuencia aumenta la velocidad de
reproducción celular con el objeto de eliminar al
hongo por descamación de las células
infectadas.
● Componente sérico SIF (Factor sérico
inhibitorio), limita el área de extensión del
estrato córneo y participa en el control de la
infección micótica.
9
12. 1. Propia de niños
2. Se cura sola en la pubertad
3. M. canis y T. tonsurans
4. Adultos portadores asintomaticos
5. Puede ser inflamatoria o no inflamatoria
Tiña de la cabeza o tinea capitis
Querion de celso
Tiña fávica o favus Tricofitia
Microsporica
11
13. TIÑA DE LA CARA Y BARBA
Afecta a cualquier grupo de edad, pero
se observa más frecuentemente en
niños y adultos jóvenes, con un leve
predominio en mujeres.
En general, los reservorios animales de
dermatofitos zoofílicos, especialmente
Microsporum canis son de alcance
universal entre los animales
domésticos y ganado.
12
14. Tiña del cuerpo
Los agentes causales más
frecuentemente implicados son: M.
canis, T. rubrum y T. mentagrophytes.
Menos frecuentemente M. audouinii,
Es la infección superficial de la piel
lampiña (glabra, sin pelo), tórax,
abdomen y miembros por dermatofitos,
excepto las ingles, palmas y plantas.
13
15. Tiña inguinal
Si la infección se limita a las ingles,
quizá dependa de E. floccosum; si es
diseminada, de T. rubrum, y si es
inflamatoria, de T. mentagrophytes.
Incluye las infecciones de los
genitales, la región pubiana y la piel de
las zonas perineal y perianal producida
por hongos dermatofitos.
14
16. TIÑA DE LOS PIES
Los agentes causales más frecuentes
son el T. rubrum, T. mentagrophytes ,
epidermophyton floccosum
Es una infección dermatofítica
superficial que afecta los pies, sobre
todo los pliegues interdigitales, plantas
y esporádicamente el dorso.
15
17. TIÑA DE LAS MANOS
Modalidad hiperqueratósica, exfoliativa
o laminar, que es crónica y se origina
por T. rubrum, y una forma inflamatoria
o aguda que se debe
fundamentalmente a T. mentagrophytes
La tiña de las manos (Tiña manuum),
es una dermatofitosis superficial de la
piel de las manos (palma y dorso de
manos), causadas generalmente por
especies de trichophyton.
16
18. TIÑA DE LAS UÑAS.
Los dermatofitos más comúnmente
aislados son T. rubrum (85%), T.
mentagrophytes (10%).
El término onicomicosis (tiña causada
por mohos) es más amplio, es la
infección fúngica del aparato ungueal
por dermatofitos, levaduras y otras
especies de hongos TIÑA UNGUEAL
para la causada por dermatofitos.
17
19. Granuloma tricofítico o dermatofítico
Predomina en mujeres, en quienes se
localiza en las extremidades inferiores, y
se presenta antecedente de rasurado de
las mismas; en otros sitios, casi siempre
hay uso previo prolongado de
glucocorticoides
En las formas solitarias, la inmunidad
celular es adecuada y la tricofitina es
positiva. En las modalidades
diseminadas, se encuentra algún grado
de alteración inmunitaria
20. Epidemiología
OMS considera que la prevalencia global es del 20%.
● España que es del 20.8%
● Brasil del 26.3%
● Irán del 24%
Singapur se ha estimado que se
presentan 2,500 casos
anualmente.
En México, las dermatofitosis
constituyen el 70 al 80% de todas
las micosis.
18
21. OBSERVACIÓN MICROSCÓPICA DIRECTA
La observación de la muestra obtenida y aclarada se
observa con microscopia de baja resolución, en
busca de hifas, esporas o células en gemación.
CULTIVO
Para la identificación del género y la especie del
agente causante
EL EXAMEN CON LUZ DE WOOD
El estudio con luz de Wood permite establecer si los
pelos presentan fluorescencia o no
DIAGNOSTICO
19
22. Tratamiento
Tratamiento
farmacológico
Tiña de la cabeza
Formas diseminadas
Griseofulvina
a dosis de 10
mg/kg/día
Los diferentes preparados pueden ser del grupo de
los azoles, los tiocartbamatos y morfolinas.
Tiña de las uñas
Primera línea
Fluconazol, itraconazol
y terbinafina, a las
siguientes dosis de 150
mg/semana, de 3-10
mg/Kg/día y de 3-6
mg/kg/día,
respectivamente.
→ Itraconazol 200 mg c/12 h, durante una semana, pausa
de 3 semana, reiniciar nuevamente, dos pulso más.
→ Terbinafina 250 mg /día, durante cuatro semanas,
pausa durante cuatro semanas, seguido de cuatro
semanas adicionales a la misma dosis.
Segunda línea
Cualquiera de los
medicamentos se
administra al menos
durante 10 semanas.
Disminuir las
interacciones con
otros fármacos y las
complicaciones.
Los antifúngicos, se
aplican diariamente
durante tres semanas..
20
23. Prevencion
1. Evita tocar las áreas infectadas de piel de otras personas.
2. Evitar el contacto con animales infectados como gatos o
perros.
3. Mantener la piel limpia y seca.
4. Utilizar champú regularmente, especialmente después de un
corte de cabello.
5. Lavar regularmente la ropa que utilizas para hacer deporte.
6. Ducharse siempre después de practicar deporte porque los
dermatofitos se depositan en la piel y proliferan con el sudor
(calor y humedad).
7. Evitar compartir ropas, toallas, cepillos para el cabello, peines,
gorros u otros elementos de cuidado personal. Estos
elementos se deben lavar y secar muy bien después de
usarlos.
8. Usar sandalias o zapatos en gimnasios, vestuarios y piscinas.
No andar descalzo en zonas públicas.
9. Evitar tocar mascotas que tengan parches sin pelo.
10. Lavarse las manos a menudo después de tocar animales
domésticos.
21
24. Caso clínico
Se presenta el caso de una paciente de 10 años de edad que acudió a una unidad por presentar
dermatosis de un año de evolución, localizada en cabeza de la que comprometía cara y de esta
última, mejilla derecha, párpados superior e inferior derechos y dorso nasal. Bilateral y asimétrica.
Dicha dermatosis estaba constituida por eritema y escama que confluyen para formar una placa
de 15 por 10 cm, de bordes bien definidos, elevados, con algunas micro-vesículas y costras
melicéricas. De evolución crónica y asintomática.
22
25. Caso clínico
Había recibido múltiples tratamientos tópicos conjugados
(antibiótico, antimicótico y esteroide), sin éxito.
En el resto de la piel y anexos la paciente no presentaba
lesiones ni tenía antecedentes patológicos o no patológicos
de importancia para su dermatosis. Con la sospecha clínica
de tiña facial con corticoestropeo se inició un interrogatorio
dirigido en busca de la fuente de contagio, se nos informó
que la paciente tenía la costumbre de realizar pedicura a su
padre, a quien al examinar encontramos clínicamente con
onicomicosis total.
23
26. Caso clínico
El diagnóstico definitivo de tiña facial por T. rubrum con corticoestropeo se confirmó por examen
micológico directo y cultivo en el laboratorio de micología de esta unidad dermatológica. Se inició
tratamiento tópico con ketoconazol en crema, obteniendo curación de 100% en un periodo de
cuatro semanas.
24
27. Bibliografías
● Molina López, J; López Martínez, R & Sanchez Vega, J. (2019). Microbiología y
Parasitología Médicas de Tay. Quinta edición. Pp. 859-863. Booksmedicos. Mendez
Editores. Cd. de México.
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