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Dengue Management
Dr. Afia Farhana
MBBS,MD phase A Resident
(Oncology)
Medicine Unit V
RAJSHAHI MEDICAL COLLEGE
Dengue Virus
The dengue virus forms a distinct complex under the genus flavi
viruses based on antigenic and biological characteristics. There are
four dengue virus serotypes which are designated as DENV-1,
DENV-2, DENV-3, and DENV-4.
Aedes aegypti is the primary vector
and Aedes albopictus is secondary
vector for dengue in Bangladesh.
Vector
Transmission Cycle
The female usually becomes infected with the dengue virus when it
takes a blood meal from a person during the acute febrile (viremia)
phase of dengue illness. After an extrinsic incubation period of 8 to 10
days, the mosquito becomes infected. The virus is transmitted when
the infected female mosquito bites and injects its saliva into the wound
of the person bitten.
The cycle of dengue continues by this process. Dengue begins
abruptly after an intrinsic incubation period of 4 to 7 days (range 3–14
days). There is also evidence of vertical transmission of dengue virus
from infected female mosquitoes to the next generation.
This Photo by Unknown Author is licensed under CC BY-NC-ND
Flow Chart of Pathophysiology of dengue infection
Clinical Manifestation of Dengue Infection
Many patients infected with dengue virus remain asymptomatic.
Others, after an incubation period of 4-7 (range 3-14) days, develop
a febrile illness the manifestations of which are similar and
overlapping in nature grouped into ‘Dengue Syndromes’ which
encompass the following:
• Undifterentiated fever
• DF
• DHF
• Expanded Dengue Syndrome (rare)
Clinical Manifestation of Dengue
About fluid
• Colloidal osmotic pressure(COP) of 20% albumin 8 times higher than normal
human serum.
• COP of fresh donar plasma 30% less than normal human serum.
• COP of 70% Dextrans is 2 times higher than normal human serum.
• COP of 40% Dextran & gelatine (Haemacil) are controversial .
• COP of Hydroxy ethyl starch ( Plasmasol) vary from strength to strength .(.5 -3
times) than normal human serum.
Thank you

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Dengue PPT by Dr Afia.pptx

  • 1. Dengue Management Dr. Afia Farhana MBBS,MD phase A Resident (Oncology) Medicine Unit V RAJSHAHI MEDICAL COLLEGE
  • 2. Dengue Virus The dengue virus forms a distinct complex under the genus flavi viruses based on antigenic and biological characteristics. There are four dengue virus serotypes which are designated as DENV-1, DENV-2, DENV-3, and DENV-4.
  • 3.
  • 4. Aedes aegypti is the primary vector and Aedes albopictus is secondary vector for dengue in Bangladesh. Vector
  • 5. Transmission Cycle The female usually becomes infected with the dengue virus when it takes a blood meal from a person during the acute febrile (viremia) phase of dengue illness. After an extrinsic incubation period of 8 to 10 days, the mosquito becomes infected. The virus is transmitted when the infected female mosquito bites and injects its saliva into the wound of the person bitten.
  • 6. The cycle of dengue continues by this process. Dengue begins abruptly after an intrinsic incubation period of 4 to 7 days (range 3–14 days). There is also evidence of vertical transmission of dengue virus from infected female mosquitoes to the next generation.
  • 7. This Photo by Unknown Author is licensed under CC BY-NC-ND
  • 8.
  • 9.
  • 10. Flow Chart of Pathophysiology of dengue infection
  • 11.
  • 12.
  • 13.
  • 14.
  • 15. Clinical Manifestation of Dengue Infection Many patients infected with dengue virus remain asymptomatic. Others, after an incubation period of 4-7 (range 3-14) days, develop a febrile illness the manifestations of which are similar and overlapping in nature grouped into ‘Dengue Syndromes’ which encompass the following: • Undifterentiated fever • DF • DHF • Expanded Dengue Syndrome (rare)
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  • 50. About fluid • Colloidal osmotic pressure(COP) of 20% albumin 8 times higher than normal human serum. • COP of fresh donar plasma 30% less than normal human serum. • COP of 70% Dextrans is 2 times higher than normal human serum. • COP of 40% Dextran & gelatine (Haemacil) are controversial . • COP of Hydroxy ethyl starch ( Plasmasol) vary from strength to strength .(.5 -3 times) than normal human serum.
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