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Cell Phone Radiation
Health, Safety Standards,
Precaution
Dariusz Leszczynski,

PhD, DSc

Research Professor
STUK - Radiation and Nuclear Safety Authority, Helsinki, Finland
&
Adjunct Professor
Disclaimer: all University of Helsinki, Finland my employer
opinions are my own and not of

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?
Who am I?
Was a member of the IARC Working Group that in
May 2011 classified cell phone radiation as a possible
human carcinogen
Full CV available on my science blog:
‘BRHP – Between a Rock and a Hard Place’

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?
Epidemiological evidence

• Epidemiological studies lack reliable dosimetric information
• Do not consider sufficiently cancer latency
• Studied cancer only; what about other ailments

Human volunteer studies

• Lack of biomarkers of response
• Too much relying on the subjective observations of volunteers

Animal studies

• Negative results do not mean no effect in humans

In vitro studies

• Needed for discovering the mechanisms
• Huge diversity in design causes problems with interpretation

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?
Evidence of biological effects remains
contradictory
• Effect on DNA
• Indirect DNA damage or inhibition of repair of spontaneously
occurring (radiation unrelated) damage of DNA?
•

Effect on gene & protein expression
• Observed in vitro (genes & proteins) and in human volunteers
(proteins; genes not studied yet)

•

Cellular stress response – candidate for the mechanism?
• Observed in different cell models and with different exposures
• Might affect expression of genes involved in cancer

•

Physiological and health impact , if any, of the above
biological effects remains undetermined

•

Effects are non-thermal

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?
Leszczynski et al. 2002

Caraglia et al. 2005

Friedman et al. 2007

Buttiglione et al. 2007

Yu et al. 2008

Possible mechanism
Cell phone radiation affects stress response

Lee et al. 2008
Invoking the Precautionary Principle
“Whether or not to invoke the Precautionary
Principle is a decision exercised where scientific
information is insufficient, inconclusive, or
uncertain and where there are indications that the
possible effects on environment, or human, animal
or plant health may be potentially dangerous and
inconsistent with the chosen level of protection.”
Commission of the European Communities
Brussels, 2.2.2000; COM(2000) 1 final

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?
Conclusions
IARC classification of the cell phone radiation as a possible
carcinogen is a sufficient reason for invoking Precautionary
Principle
Current safety standards are insufficient because use of an offthe-shelf cell phone (considered to be safe) was shown to
increase the risk of brain cancer
Users, especially children, should be encouraged to limit
exposures
Research should continue to find out how human body
reacts to cell phone radiation

The Commonwealth Club of California
Dariusz Leszczynski in Expert Roundtable:
Skeptical About Cell Phones and Health?

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Dariusz Leszczynski in Expert Roundtable; San Francisco Dec. 9, 2013

  • 1. Cell Phone Radiation Health, Safety Standards, Precaution Dariusz Leszczynski, PhD, DSc Research Professor STUK - Radiation and Nuclear Safety Authority, Helsinki, Finland & Adjunct Professor Disclaimer: all University of Helsinki, Finland my employer opinions are my own and not of The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?
  • 2. Who am I? Was a member of the IARC Working Group that in May 2011 classified cell phone radiation as a possible human carcinogen Full CV available on my science blog: ‘BRHP – Between a Rock and a Hard Place’ The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?
  • 3. Epidemiological evidence • Epidemiological studies lack reliable dosimetric information • Do not consider sufficiently cancer latency • Studied cancer only; what about other ailments Human volunteer studies • Lack of biomarkers of response • Too much relying on the subjective observations of volunteers Animal studies • Negative results do not mean no effect in humans In vitro studies • Needed for discovering the mechanisms • Huge diversity in design causes problems with interpretation The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?
  • 4. Evidence of biological effects remains contradictory • Effect on DNA • Indirect DNA damage or inhibition of repair of spontaneously occurring (radiation unrelated) damage of DNA? • Effect on gene & protein expression • Observed in vitro (genes & proteins) and in human volunteers (proteins; genes not studied yet) • Cellular stress response – candidate for the mechanism? • Observed in different cell models and with different exposures • Might affect expression of genes involved in cancer • Physiological and health impact , if any, of the above biological effects remains undetermined • Effects are non-thermal The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?
  • 5. Leszczynski et al. 2002 Caraglia et al. 2005 Friedman et al. 2007 Buttiglione et al. 2007 Yu et al. 2008 Possible mechanism Cell phone radiation affects stress response Lee et al. 2008
  • 6. Invoking the Precautionary Principle “Whether or not to invoke the Precautionary Principle is a decision exercised where scientific information is insufficient, inconclusive, or uncertain and where there are indications that the possible effects on environment, or human, animal or plant health may be potentially dangerous and inconsistent with the chosen level of protection.” Commission of the European Communities Brussels, 2.2.2000; COM(2000) 1 final The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?
  • 7. Conclusions IARC classification of the cell phone radiation as a possible carcinogen is a sufficient reason for invoking Precautionary Principle Current safety standards are insufficient because use of an offthe-shelf cell phone (considered to be safe) was shown to increase the risk of brain cancer Users, especially children, should be encouraged to limit exposures Research should continue to find out how human body reacts to cell phone radiation The Commonwealth Club of California Dariusz Leszczynski in Expert Roundtable: Skeptical About Cell Phones and Health?