Cystic fibrosis is caused by a genetic mutation that results in thick, sticky mucus in the lungs and digestive system. It is most common in Caucasian Americans and is inherited when each parent passes on one defective gene. Symptoms often appear in early childhood and include persistent coughing, weight loss, and increased sweat and mucus production. While there is no cure, treatments focus on lung clearance and nutrition to manage symptoms and prolong life expectancy, which has risen to an average of around 35 years.
Cystic fibrosis (also known as CF or mucoviscidosis) is a recessive multi-system genetic disease characterized by abnormal transport of chloride and sodium across epithelium, leading to thick, viscous secretions in the lungs, pancreas, liver, intestine.[Yankas JR, et al. (2004). "Cystic fibrosis adult care consensus conference report". Chest 125: 1-39.]
Cystic fibrosis (also known as CF or mucoviscidosis) is a recessive multi-system genetic disease characterized by abnormal transport of chloride and sodium across epithelium, leading to thick, viscous secretions in the lungs, pancreas, liver, intestine.[Yankas JR, et al. (2004). "Cystic fibrosis adult care consensus conference report". Chest 125: 1-39.]
cystic fibrosis is a hereditary disease which can transfer from one generation to another generation. it is only effective one both of two partner contain defective gene, if only one partner contain the defective gene he/se will be carrier no an effective
"Genetic Testing: Do You Really Want To Know What's In Your Genes?"
This Science Pub took place at the Bagdad Theater in Portland, Oregon, on Monday, July 6, 2009. It was presented by Dr. Lisa Sardinia, Associate Professor at Pacific University and Associate director of the Pacific Institute for Ethics and Social Policy.
http://www.pacificu.edu/as/biology/faculty/sardinia.cfm
5. Etiology No incubation period Signs Delayed growth Weight loss Increased coughing Chronic lung infections
6. Etiology Continued Symptoms Nausea Nasal congestion Sinus pain or pressure Stomach pain Fatigue Loss of appetite Fever Increased sweat production
7. Diagnosis Blood test to look for variation in the gene known to cause CF Immunoreactivetrypsinogen (IRT) test screens newborns and a high level of IRT suggests possible CF Sweat Chloride Test is the standard test for CF. A high salt level in the person’s sweat is a sign of the disease
8. Pathophysiology Chronic disease Pulmonary, gastrointestinal, heart, and reproductive problems are all common Pulmonary Chronic infections of the lung emphytsema progressive respiratory insufficiency Heart Pulmonary Heart Disease Overproduction of red blood cells Gastrointestinal pancreatic insufficiency intestinal obstruction cirrhosis of the liver Reproductive 98% infertility in males
9. Prognosis and Treatment There is no cure or a way to prevent Cystic Fibrosis The average life span is approximately 35 years Death is usually caused by lung complications Treatment includes Antibiotics Inhaler medicines Oxygen therapy Diet high in protein and calories Pancreatic enzymes Vitamin supplements