Arthur Castleton has extensive experience in biomedical research and tissue engineering. He has worked on projects involving stem cell culture, biomaterial characterization, and the development of biomedical devices. As an undergraduate, he has published journal articles, presented at numerous conferences, and mentored other students in the laboratory. Upon graduation from Brigham Young University, Castleton will receive a Bachelor of Science in Chemical Engineering.

1. overhauled, oversaw paid, participated, passed, patterned, penalized, perceived, performed, per mitted, per suaded, phased, out, pinpointed, pioneered, placed, planned, polled, prepared, presented, preserved, presided, prevented, priced, printed, prioritized, probed, processed, procured, produced, profiled, programmed, projected, promoted, prompted, proposed, prov Word python C++ Aut ocad solidw orks regulatory government six sigma 6 sigma lean dex manufacturing
uncovered undertook unified united updated upgraded used utilized validated valued verified viewed visited weighed welcomed widened witnessed won w orked wrote
ARTHUR A. CASTLETON
Proficiency Microsoft Office excel
EDUCATION
Brigham Young University
Bachelor of Science in Chemical Engineering to be awarded April 2016
 BYU Chapter of the Biomedical Engineering Society – Cofounder and Public Relations Officer
 GPA: 3.2/4.0
.
TECHNICAL EXPERIENCE
Senior Research Assistant – Tissue Engineering (Part-time) 4/2013-Current
Brigham Young University – Provo, UT – Dr. Alonzo Cook PhD
 Studied the cytotoxicity, hemolysis, and structural capacity of porcine cardiac ECM with various human cell types
 Designed and directed experiments while mentoring 12 undergraduate students
 Additional work included stem cell culture, grant writing, and refining the efficacy of tissue decellularization
R&D Intern – Biomedical Devices 6/2015-8/2015
ACell Inc. – Columbia, MD – Dr. Nikhil Gheewala PhD
 Conducted prototype development of 4 high-priority biomedical devices
 Assisted engineers in product development, processing, and design control
 Utilized skills in mechanical testing, use of polymers, computational analysis, and innovation
Student Scientist – Regenerative Medicine 4/2014-12/2014, 4/2015-6/2015
McGowan Institute for Regenerative Medicine – Pittsburgh, PA – Dr. Stephen Badylak DVM, PhD, MD
 Established and characterized a product to be employed as a gold standard by our industry collaborators
 Pioneered a method to prepare colonic ECM then characterized its in vitro and in vivo bioactivity
 Compared methods of hydrogel sterilization and administered 3 applied product animal studies
R&D Intern – Biofuel Characterization 1/2014-4/2014
Idaho National Laboratories – Idaho Falls, ID – Dr. Tyler Westover PhD
 Spectroscopically determined the elemental components of 20+ potential alternative energy sources
 Adjusted SOPs to improve safety, automated manual processes, and utilized MATLAB and Excel data analysis skills
 Processed over 5000 kg of various biomaterial samples, completed the SULI program
Research Assistant and Lab Safety Officer – Protein Engineering (Part-time) 1/2013-6/2013
Brigham Young University – Provo, UT – Dr. Brad Bundy PhD
 Performed, designed, and supervised PCRs, bacterial cell culture, and cell-free protein synthesis
 Presented monthly technique & safety training. Certified to supervise the use of radioactive materials
 Optimized cell-free protein reactions to increase yields by 35%
General Technician 6/2010-8/2012
A Better Handyman and Contractor Service – Lynnwood, WA – John Pritchett
 Performed carpentry, contracting, plumbing, painting, electrical, masonry, demolition, and general repair
 Actively practiced problem solving of any household problem a human could make
 Demonstrated skill utilizing equipment and carrying out hands-on projects
SKILLS AND ACHIEVEMENTS
 Eagle Scout, earned an Associates of Science degree at 18, volunteered over 800 hours at the Children’s Hospital of
Pittsburgh and various soup kitchens over the last two years
 Proposed and was awarded funding to start and lead the project “Differentiating stem cells into cardiomyocytes
utilizing extracellular matrix”
 Utilized people-skills, ambition, and leadership as a 3 sport athlete, team captain, and BSA patrol leader
 Demonstrated technical communication skills while producing 16 scientific presentations and publications,
cofounding the BYU Chapter of the Biomedical Engineering Society, and earning $15,000+ from merit scholarships
 Additional proficiencies include programming in MATLAB, using various CAD programs, mechanical testing,
utilization of polymers, production and application of biomaterials, immunohistochemistry, assay development
and optimization, stem cell and general cell culture, animal research, microscope imaging, PCR, SEM, prototyping,
developing SOPs, DFMEAs, Six Sigma, data analysis, statistics, public speaking, and technical writing
19815 10th
Pl W
Lynnwood, WA 98036
206-335-2228
Castleton@byu.edu

2. overhauled, oversaw paid, participated, passed, patterned, penalized, perceived, performed, per mitted, per suaded, phased, out, pinpointed, pioneered, placed, planned, polled, prepared, presented, preserved, presided, prevented, priced, printed, prioritized, probed, processed, procured, produced, profiled, programmed, projected, promoted, prompted, proposed, prov Word python C++ Aut ocad solidw orks regulatory government six sigma 6 sigma lean dex manufacturing
uncovered undertook unified united updated upgraded used utilized validated valued verified viewed visited weighed welcomed widened witnessed won w orked wrote
JOURNAL PUBLICATIONS
 Londono R, Dziki J, Castleton AA, Saldin LT, Keane TJ, Badylak SF. “Preparation and characterization of a biologic
scaffold from esophageal muscularis externa”. In preparation.
 Momtahan N, Panahi T, Poornejad N, Stewart MG, Vance BR, Struk JA, Castleton AA, Roeder BL, Sukavaneshvar S,
Cook AD. “Using Hemolysis as a Novel Method for Assessment of Cytotoxicity”. American Society for Artificial
Internal Organs Journal. Ahead of print.
 Keane TJ, Dziki J, Castleton AA, Faulk DM, Messerschmidt V, Londono R, Reing JE, Valenkar SS, Badylak SF.
“Preparation and characterization of a Colonic Mucosal Extracellular Matrix”. Journal of Biomedical Materials
Research Part B: Applied Biomaterials. October 2015. doi: 10.1002/jbm.b.33556
 Momtahan N, Poornejad N, Struk JA, Castleton AA, Herrod BJ, Vance BR, Eatough JP, Roeder BL, Reynolds PR, Cook
AD. “Automation of Pressure Control Improves Whole Porcine Heart Decellularization”. Tissue Engineering Part C.
November 2015. 21(11): 1148-1161. doi:10.1089/ten.tec.2014.0709.
 Keane T, DeWard A, Londono R, Saldin LT, Castleton AA, Carey L, Nieponice A, Lagasse E, Badylak SF. “Tissue-
Specific Effects of Esophageal Extracellular Matrix”. Tissue Engineering Part A. September 2015, 21(17-18): 2293-
2300. doi:10.1089/ten.tea.2015.0322.
CONFERENCE PRESENTATIONS
 Castleton AA, Pfiefer D, Johnson K, Vance BR, Stewart MG, Goodman RJ, Zimmerman M, Bloxham J, Cook AD.
“Differentiating stem cells into cardiomyocytes utilizing extracellular matrix”. Tenth Annual Utah Conference on
Undergraduate Research. February 2016.
 Castleton AA, Momtahan N, Stewart MG, Vance BR, Bloxham J, Cook AD. “Utilizing porcine scaffolds for human
cardiac tissue engineering”. Emerging Ideas in Biomedical Research. January 2016. 1st
Place.
 Castleton AA, Momtahan N, Vance BR, Cook AD. “Determining the efficacy of coaxing porcine cardiac scaffolds
into human hearts”. American Institute of Chemical Engineers Annual Meeting. October 2015.
 Smoulder AL, Castleton AA, Keane TJ, White LJ, Zhang L, Badylak SF. “The Effects of Terminal Sterilization on
Extracellular Matrix Hydrogel Stiffness and Biologic Activity”. Biomedical Engineering Society Annual Meeting.
October 2015.
 Momtahan N, Vance BR, Eatough JP, Castleton AA, Roeder BL, Cook AD. “Recellularization of Whole Porcine Heart
with Human Cardiac Fibroblasts and Endothelial Cells”. 4th
TERMIS World Congress. September 2015.
 Keane TJ, White LJ, Dearth C, Badylak SF, Castleton AA. “Methods and Effects of Sterilization on Extracellular
Matrix Hydrogels”. 4th
TERMIS World Congress. September 2015.
 Castleton AA, Cook AD. “Advancing methods of Cardiac Tissue Engineering”. Western Regional AICHE Conference.
April 2015.
 Castleton AA, Turner NJ, Keane TJ, Badylak SF. “Applications of ECM-derived biomaterials”. McGowan Institute
Research Meeting. December 2014.
 Castleton AA, Westover TL. “Biomass Characterization”. U.S. Department of Energy SULI Conference. April 2015.
 Castleton AA, Ford MK, Cook AD. “Bioartificial Organs”. Eighth Annual Utah Conference on Undergraduate
Research. February 2014.
 Momtahan N, Castleton AA, Ford MK, Gentile S, Herrod B, Howarth H, Russell C, Smith T, Cook AD. “Cardiac Tissue
Engineering”. Emerging Ideas in Biomedical Research. October 2013. Student’s Choice Award.