Current Situation in Control Strategies and Health Systems in Myanmar, Asia by PROFESSOR DR. NE WIN, DIRECTOR (LABORATORY AND BLOOD SERVICE), MINISTRY OF HEALTH, UNION OF MYANMAR
Thalassemia in Viet Nam by Prof.Nguyen Anh Tri MD Ph.D Director - National institute of Hematology and Blood Transfusion President – Viet Nam Thalassemia Association
Thalassemia in Laos: Situation Analysis by Dr. Sourideth Sengchanh, Dr. Alongkone Phengsavanh, Assoc. Prof. Dr. Khampe Phongsavat, University of Health Sciences, Vientiane, Laos. Presented by Assoc. Prof. Dr. Khampe Phongsavat.
Thalassemia in Viet Nam by Prof.Nguyen Anh Tri MD Ph.D Director - National institute of Hematology and Blood Transfusion President – Viet Nam Thalassemia Association
Thalassemia in Laos: Situation Analysis by Dr. Sourideth Sengchanh, Dr. Alongkone Phengsavanh, Assoc. Prof. Dr. Khampe Phongsavat, University of Health Sciences, Vientiane, Laos. Presented by Assoc. Prof. Dr. Khampe Phongsavat.
Current Situation in Control Strategies and Health Systems in Philippines by ERNESTO d’J. YUSON MD, Thalassemia Center of the Philippines, Balikatang Thalassaemia
Risk Assessment and Management of Cardiovascular Diseases - an English Approach. Lynam E. Conference on Cardiovascular Diseases (Madrid: Ministry of Health and Social Policy; 2010).
The Solomon Islands HiT determines that the country’s health system has significant weaknesses but also considerable strengths. Despite the range and difficulty of issues facing policy-makers in the Solomon Islands, there have been significant achievements in health, including considerable progress in advancing population health status. The performance of the health system is positive, achieving high coverage, high satisfaction levels, and steady progress on health outcomes. Nonetheless, the country faces important health challenges that could undermine development gains made to date
CURRENT SITUATION IN CONTROL STRATEGIES & HEALTH SYSTEMS IN ASIA - CAMBODIA by PRAK PISETH RAINGSEY, MD, DND, MPH Director Preventive Medicine Department MINISTRY OF HEALTH
Bone marrow transplantation for thalassemia in lower resource settings - The Cure2Children Foundation experience in Pakistan. By Dr Naila Yaqub, Assistant Professor, Bone Marrow Transplant unit, The Children hospital, PIMS, Pakistan
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The Solomon Islands HiT determines that the country’s health system has significant weaknesses but also considerable strengths. Despite the range and difficulty of issues facing policy-makers in the Solomon Islands, there have been significant achievements in health, including considerable progress in advancing population health status. The performance of the health system is positive, achieving high coverage, high satisfaction levels, and steady progress on health outcomes. Nonetheless, the country faces important health challenges that could undermine development gains made to date
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Bone marrow transplantation for thalassemia in lower resource settings - The Cure2Children Foundation experience in Pakistan. By Dr Naila Yaqub, Assistant Professor, Bone Marrow Transplant unit, The Children hospital, PIMS, Pakistan
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Understanding the molecular mechanisms leading to reactivation or derepression of γ-globin gene by Jim Vadolas, Cell and Gene Therapy Group, Murdoch Childrens Research Institute, Royal Children’s Hospital
Treatment of patients with β‐Thalassaemias by Professor John Porter, University College London, Joint Red Cell Disorders Unit, UCLH and Whittington Hospitals
Genetic Screening and Prenatal Diagnosis of Thalassemias and Hemoglobinopathies in Taiwan Today by Ching-Tien Peng, MD, MPH, Superintendent & Prof. of The Children’s Hospital, China Medical University & Hospitals, Prof. of Biotechnology, Asia University, Taichung, Taiwan
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
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CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Myanmar - Current Situation in Control Strategies and Health Systems in Asia
1. CURRENT SITUATION IN CONTROL
STRATEGIES AND HEALTH SYSTEMS
IN ASIA – MYANMAR
PROFESSOR DR NE WIN
DR.
DIRECTOR (LABORATORY AND BLOOD SERVICE)
MINISTRY OF HEALTH
UNION OF MYANMAR
2. DEMOGRAPHIC DATA
• - about 57 million population
• - 135 minor ethnic groups and seven
major indigenous races
• - annual bi th rate 2 3%
l birth t 2.3%
• - 12,000,000 kyats pe yea
,000,000 yats per year
• - 1.2% of total budget on health
3. HEALTH SYSTEM
• Both private and public sector are under
y
Health ministry
• Cost sharing system; free of charge
system
• No special policies for chronic diseases
• Nor for hemoglobin disorders
4. EPIDEMIOLOGY
• ALPHA THAL CARRIER RATE 10-14%
• BETA THAL CARRIER RATE 0 4 – 1 8 %
0.4 1.8
• E-THAL CARRIER RATE 20-25%
• S-THAL CARRIER RATE – NIL
• 1300 – 6500 newborns with transfusion
dependent thalassemia (both alpha and
beta) e er year
every ear
5. PATIENT REGISTRY
• OUT-PATIENT AND IN-PATIENT
REGISTRY IN EVERY HOSPITAL
• DCR AT CHILDREN HOSPITAL
• BLOOD TRANSFUSION SERVICES AT
STATE AND DIVISIONAL HOSPITAL
• NATIONAL BLOOD CENTER
7. DIAGNOSTIC SERVICES
AVAILABLE
• Population screening – Nil
P l ti i
• Prenatal diagnosis – Nil
g
• Antenatal diagnosis – Nil
• Genetic counseling – Nil
• Molecular diagnostic facilities – available
only at NHL
• Primary level – Nil ; Regional – Nil
y g
• National – available
8. BLOOD AND BLOOD
COMPONENTS
• National Blood Policy founded in 2010
• National blood and blood product law 2003
9. IRON CHELATION
• All chelators available
• Easily accessible at central level hospital
• given by community cost sharing system
• DFO - about 10% of cases (according to
DCR, Children hospital data)
C , C d e osp ta
10. • Multi disciplinary teams to monitor cardiac
and endocrine complications – only at the
p y
central / tertiary level hospitals
11. • MRI facilities are available only at tertiary
p
care hospitals