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Caveats and Comments
1
Overview:
This is my analysis, not Stanford’s. My plots and regressions are intended to understand the trajectory of COVID. It is not confidential and can be freely shared.
The R program code and PowerPoint files are available at https://github.com/StevenLShafer/COVID19/. Please contact me at steven.shafer@Stanford.edu if you
would like to be added or removed from the recipient list. Suggestions are most welcome! You are welcome to use the R code on GitHub for any purpose.
I am attempting to keep the analysis and commentary apolitical. I am now including partisan lean as a metric to help understand the epidemic. I occasionally point
out misrepresentations by government officials. I occasionally point out where government recommendations have placed Americans at increasing risk.
I try to provide a daily update in the morning, except Sundays. My analysis my be delayed by my clinical responsibilities as a Stanford anesthesiologist.
There is a lot of information on the figures. If something isn’t clear, please see the explanation on slide 2.
Data sources:
• USA Case Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_confirmed_US.csv
• USA Death Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_deaths_US.csv
• USA Testing and Hospitalization Data: https://raw.githubusercontent.com/COVID19Tracking/covid-tracking-data/master/data/states_daily_4pm_et.csv
• Global Case Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_confirmed_global.csv
• Global Death Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_deaths_global.csv
• Global Testing Data: https://raw.githubusercontent.com/owid/covid-19-data/master/public/data/owid-covid-data.csv
• Mobility Data: https://www.gstatic.com/covid19/mobility/Global_Mobility_Report.csv
• Partisan Lean: MIT Election Data and Science Lab: https://doi.org/10.7910/DVN/VOQCHQ/HEIJCQ
• Ensemble Model: https://github.com/reichlab/covid19-forecast-hub/raw/master/data-processed/COVIDhub-ensemble/2020-xx-xx-COVIDhub-ensemble.csv
Models:
1. Future projections of case numbers are based on the Gompertz function (https://en.wikipedia.org/wiki/Gompertz_function): log 𝑐𝑢𝑚𝑢𝑙𝑎𝑡𝑖𝑣𝑒 𝑐𝑎𝑠𝑒𝑠 =
𝑐𝑢𝑟𝑟𝑒𝑛𝑡 𝑐𝑎𝑠𝑒𝑠 + 𝑚𝑎𝑥𝑖𝑚𝑢𝑚 𝑐𝑎𝑠𝑒𝑠 − 𝑐𝑢𝑟𝑟𝑒𝑛𝑡 𝑐𝑎𝑠𝑒𝑠 1 − 𝑒−𝑘 𝑡 . This is a naïve asymptotic model. k is the rate constant, such that log(2) / k = time to 50%
rise. t is the number of days. Wikipedia The Gompertz function is estimated from the last 3 weeks of data for cumulative cases (red dots in the figures).
Deaths are predicted from a log linear regression of deaths over the past 21 days. For the US, and individual states, I am also including the 98% prediction
interval from the COVID-19 Forecast Hub (https://covid19forecasthub.org/).
2. The rate of change in daily cases and deaths is the slope of delta cases / day over the last 14 days, divided by the average number of cases.
Locations
The locations for the modeling are where Pamela and I have family and friends, locations of interest to friends and colleagues, or countries in the news (e.g.,
China, South Korea, Sweden, Brazil) or with significant economic impact on the United States (e.g., Japan, Canada, Mexico). Locations are easy to add.
Stay safe, well, resilient, and kind.
Steve Shafer
steven.shafer@Stanford.edu
2,586,092
152,804
1
10
100
1,000
10,000
100,000
1,000,000
10,000,000
100,000,000
Actual(points)/Predicted(line)
Phase
Pre-Model
Modeled
Deaths
Tests
USA projection as of 2020-05-27
0
10,000
20,000
30,000
0
2,000
4,000
6,000
Cases/Day
Deaths/Day
Cases: 1,662,302 (32,123) -- Deaths: 98,220 (829) -- Case Mortality: 5.9% -- Daily Change in Cases: -0.5%
Explanation of the Figures
2
Brown dots:
cumulative tests
Red dots: cumulative cases
used to estimate Gompertz
function, presently set to last
3 weeks
Red line: predicted cumulative
cases based on the Gompertz
function estimated from the red
dots
Red number: total cases
on June 30th, based on
the Gompertz function
estimated from the red
dots
Black number: total
Deaths on July 31th,
based on log-linear
regression of the past
21 days
Black line: predicted
cumulative deaths, based
on a log linear regression
of deaths over past 21
days.
Axis for deaths / day, usually
1/10th of the axis for cases /
day on the left side of the
figure.
Green line: linear regression
over 8 days, used to calculate
percent increase / decrease
(see below)
Daily change in cases,
calculated as the slope of the
green line (above left) /
number of new cases
yesterday.
Case mortality:
cumulative deaths
/ cumulative cases.
Cases / day calculated
from cumulative cases
used to estimate the
Gompertz function
Cases / day calculated
from cumulative cases
not used to estimate the
Gompertz function
Deaths / day,
axis is on the left
Blue line: today
Blue dots: cumulative cases not
used to estimate Gompertz
function
Cumulative cases
(yesterday’s cases)
and cumulative deaths
(yesterday’s deaths)
Axis for cases / day.
Axis for deaths / day
appears to the right.
Geographic
location
Date of analysis,
also shown as
blue vertical line
below
Purple wedge: 98% ensemble
prediction interval from COVID-19
Forecast Hub (USA and US
States only)
Summary
3
Worldwide
25,605,744
906,752
1
10
100
1,000
10,000
100,000
1,000,000
10,000,000
100,000,000
Actual(points)/Predicted(line)
Phase
Pre-Model
Modeled
Deaths
Worldwide projection as of 2020-07-27
0
100,000
200,000
300,000
0
5,000
10,000
15,000
Cases/Day
Deaths/Day
Cases: 16,243,747 (204,464) -- Deaths: 648,543 (4,101) -- Case Mortality: 4.0% -- Daily Change: +0.9% Cases, +1.7% Deaths
4
USA
7,042,588
181,210
1
10
100
1,000
10,000
100,000
1,000,000
10,000,000
100,000,000
Actual(points)/Predicted(line)
Phase
Pre-Model
Modeled
Deaths
Tests
USA projection as of 2020-07-27
Mother'sDay
MemorialDay
July4th
July15,2020
0
20,000
40,000
60,000
80,000
0
1,000
2,000
3,000
4,000
Cases/Day
Deaths/Day
Cases: 4,233,923 (54,953) -- Deaths: 146,935 (470) -- Case Mortality: 3.5% -- Daily Change: -0.2% Cases, +2.0% Deaths
5
Japan, South Korea, Thailand, Vietnam
69,297
1,409
1
10
100
1,000
10,000
100,000
1,000,000
10,000,000
100,000,000
Actual(points)/Predicted(line)
Phase
Pre-Model
Modeled
Deaths
Tests
Japan, South Korea, Thailand, Vietnam projection as of 2020-07-27
0
300
600
900
0
20
40
Cases/Day
Deaths/Day
Cases: 48,434 (901) -- Deaths: 1,355 (3) -- Case Mortality: 2.8% -- Daily Change: +5.3% Cases, +5.2% Deaths
6
Western Europe
1,532,467
171,016
1
10
100
1,000
10,000
100,000
1,000,000
10,000,000
100,000,000
Actual(points)/Predicted(line)
Phase
Pre-Model
Modeled
Deaths
Tests
Western Europe projection as of 2020-07-27
0
20,000
40,000
60,000
80,000
0
1,000
2,000
3,000
4,000
Cases/Day
Deaths/Day
Cases: 1,423,687 (2,032) -- Deaths: 166,706 (21) -- Case Mortality: 11.7% -- Daily Change: +1.0% Cases, -2.6% Deaths
7

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COVID-19 Update (Summary): July 27, 2020

  • 1. Caveats and Comments 1 Overview: This is my analysis, not Stanford’s. My plots and regressions are intended to understand the trajectory of COVID. It is not confidential and can be freely shared. The R program code and PowerPoint files are available at https://github.com/StevenLShafer/COVID19/. Please contact me at steven.shafer@Stanford.edu if you would like to be added or removed from the recipient list. Suggestions are most welcome! You are welcome to use the R code on GitHub for any purpose. I am attempting to keep the analysis and commentary apolitical. I am now including partisan lean as a metric to help understand the epidemic. I occasionally point out misrepresentations by government officials. I occasionally point out where government recommendations have placed Americans at increasing risk. I try to provide a daily update in the morning, except Sundays. My analysis my be delayed by my clinical responsibilities as a Stanford anesthesiologist. There is a lot of information on the figures. If something isn’t clear, please see the explanation on slide 2. Data sources: • USA Case Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_confirmed_US.csv • USA Death Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_deaths_US.csv • USA Testing and Hospitalization Data: https://raw.githubusercontent.com/COVID19Tracking/covid-tracking-data/master/data/states_daily_4pm_et.csv • Global Case Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_confirmed_global.csv • Global Death Data: https://github.com/CSSEGISandData/COVID-19/raw/master/csse_covid_19_data/csse_covid_19_time_series/time_series_covid19_deaths_global.csv • Global Testing Data: https://raw.githubusercontent.com/owid/covid-19-data/master/public/data/owid-covid-data.csv • Mobility Data: https://www.gstatic.com/covid19/mobility/Global_Mobility_Report.csv • Partisan Lean: MIT Election Data and Science Lab: https://doi.org/10.7910/DVN/VOQCHQ/HEIJCQ • Ensemble Model: https://github.com/reichlab/covid19-forecast-hub/raw/master/data-processed/COVIDhub-ensemble/2020-xx-xx-COVIDhub-ensemble.csv Models: 1. Future projections of case numbers are based on the Gompertz function (https://en.wikipedia.org/wiki/Gompertz_function): log 𝑐𝑢𝑚𝑢𝑙𝑎𝑡𝑖𝑣𝑒 𝑐𝑎𝑠𝑒𝑠 = 𝑐𝑢𝑟𝑟𝑒𝑛𝑡 𝑐𝑎𝑠𝑒𝑠 + 𝑚𝑎𝑥𝑖𝑚𝑢𝑚 𝑐𝑎𝑠𝑒𝑠 − 𝑐𝑢𝑟𝑟𝑒𝑛𝑡 𝑐𝑎𝑠𝑒𝑠 1 − 𝑒−𝑘 𝑡 . This is a naïve asymptotic model. k is the rate constant, such that log(2) / k = time to 50% rise. t is the number of days. Wikipedia The Gompertz function is estimated from the last 3 weeks of data for cumulative cases (red dots in the figures). Deaths are predicted from a log linear regression of deaths over the past 21 days. For the US, and individual states, I am also including the 98% prediction interval from the COVID-19 Forecast Hub (https://covid19forecasthub.org/). 2. The rate of change in daily cases and deaths is the slope of delta cases / day over the last 14 days, divided by the average number of cases. Locations The locations for the modeling are where Pamela and I have family and friends, locations of interest to friends and colleagues, or countries in the news (e.g., China, South Korea, Sweden, Brazil) or with significant economic impact on the United States (e.g., Japan, Canada, Mexico). Locations are easy to add. Stay safe, well, resilient, and kind. Steve Shafer steven.shafer@Stanford.edu
  • 2. 2,586,092 152,804 1 10 100 1,000 10,000 100,000 1,000,000 10,000,000 100,000,000 Actual(points)/Predicted(line) Phase Pre-Model Modeled Deaths Tests USA projection as of 2020-05-27 0 10,000 20,000 30,000 0 2,000 4,000 6,000 Cases/Day Deaths/Day Cases: 1,662,302 (32,123) -- Deaths: 98,220 (829) -- Case Mortality: 5.9% -- Daily Change in Cases: -0.5% Explanation of the Figures 2 Brown dots: cumulative tests Red dots: cumulative cases used to estimate Gompertz function, presently set to last 3 weeks Red line: predicted cumulative cases based on the Gompertz function estimated from the red dots Red number: total cases on June 30th, based on the Gompertz function estimated from the red dots Black number: total Deaths on July 31th, based on log-linear regression of the past 21 days Black line: predicted cumulative deaths, based on a log linear regression of deaths over past 21 days. Axis for deaths / day, usually 1/10th of the axis for cases / day on the left side of the figure. Green line: linear regression over 8 days, used to calculate percent increase / decrease (see below) Daily change in cases, calculated as the slope of the green line (above left) / number of new cases yesterday. Case mortality: cumulative deaths / cumulative cases. Cases / day calculated from cumulative cases used to estimate the Gompertz function Cases / day calculated from cumulative cases not used to estimate the Gompertz function Deaths / day, axis is on the left Blue line: today Blue dots: cumulative cases not used to estimate Gompertz function Cumulative cases (yesterday’s cases) and cumulative deaths (yesterday’s deaths) Axis for cases / day. Axis for deaths / day appears to the right. Geographic location Date of analysis, also shown as blue vertical line below Purple wedge: 98% ensemble prediction interval from COVID-19 Forecast Hub (USA and US States only)
  • 4. Worldwide 25,605,744 906,752 1 10 100 1,000 10,000 100,000 1,000,000 10,000,000 100,000,000 Actual(points)/Predicted(line) Phase Pre-Model Modeled Deaths Worldwide projection as of 2020-07-27 0 100,000 200,000 300,000 0 5,000 10,000 15,000 Cases/Day Deaths/Day Cases: 16,243,747 (204,464) -- Deaths: 648,543 (4,101) -- Case Mortality: 4.0% -- Daily Change: +0.9% Cases, +1.7% Deaths 4
  • 5. USA 7,042,588 181,210 1 10 100 1,000 10,000 100,000 1,000,000 10,000,000 100,000,000 Actual(points)/Predicted(line) Phase Pre-Model Modeled Deaths Tests USA projection as of 2020-07-27 Mother'sDay MemorialDay July4th July15,2020 0 20,000 40,000 60,000 80,000 0 1,000 2,000 3,000 4,000 Cases/Day Deaths/Day Cases: 4,233,923 (54,953) -- Deaths: 146,935 (470) -- Case Mortality: 3.5% -- Daily Change: -0.2% Cases, +2.0% Deaths 5
  • 6. Japan, South Korea, Thailand, Vietnam 69,297 1,409 1 10 100 1,000 10,000 100,000 1,000,000 10,000,000 100,000,000 Actual(points)/Predicted(line) Phase Pre-Model Modeled Deaths Tests Japan, South Korea, Thailand, Vietnam projection as of 2020-07-27 0 300 600 900 0 20 40 Cases/Day Deaths/Day Cases: 48,434 (901) -- Deaths: 1,355 (3) -- Case Mortality: 2.8% -- Daily Change: +5.3% Cases, +5.2% Deaths 6
  • 7. Western Europe 1,532,467 171,016 1 10 100 1,000 10,000 100,000 1,000,000 10,000,000 100,000,000 Actual(points)/Predicted(line) Phase Pre-Model Modeled Deaths Tests Western Europe projection as of 2020-07-27 0 20,000 40,000 60,000 80,000 0 1,000 2,000 3,000 4,000 Cases/Day Deaths/Day Cases: 1,423,687 (2,032) -- Deaths: 166,706 (21) -- Case Mortality: 11.7% -- Daily Change: +1.0% Cases, -2.6% Deaths 7