This document summarizes a presentation given on caffeine safety over three decades. It discusses how caffeine was initially linked to many health issues in animal and early human studies from the 1970s-1990s, but more recent and rigorous studies have found these links to be unsupported. It reviews topics like reproductive effects, addiction potential, bone health, cancer risk, and cardiovascular effects, finding that for typical intake levels, caffeine is generally recognized as safe. While some regulatory agencies still have concerns about new products with added caffeine, the document argues the evidence shows caffeine as consumed from coffee, tea, and soda does not pose health risks and may even provide benefits.
More Coffee Longer Lasting Erections
http://buyorganiccoffee.org/1391/more-coffee-linked-to-longer-lasting-erections/
And there is one more benefit of regular and healthy organic coffee. More coffee is linked to longer lasting erections! Forbes reports on a study published in the journal PLOS ONE. Coffee consumption is linked to decreased erectile dysfunction. That is to say if a man drinks more coffee he is more likely to be able to maintain an erection for the time desired.
According to a new study out in the journal PLOS ONE, caffeine intake is linked to reduced odds of having erectile dysfunction (ED) in men who drink the equivalent of two to three cups of coffee per day. Among the lifestyle factors that are known to put a man at risk of ED - poor diet, physical inactivity, smoking, and alcohol consumptions - caffeine has not been of the biggest candidates. But the new study suggests that like other areas of physical and mental health, ED may be another beneficiary of caffeine’s fascinating benefits. Since erectile function, and dysfunction, is in some ways an extension of cardiovascular health - and caffeine is known to have certain cardiovascular benefits - the idea that it could also help ED may not be so surprising. But for men who are devout coffee drinkers, the results may come as good news.
The odds of a man having difficulty maintaining an erection for the desired length of time is about 44 percent for men age 40 and over. For men over 70 the incidence of erectile dysfunction is 70 percent. So, just how much does coffee help?
What Is the Benefit of Coffee?
Researchers found that the caffeine equivalent of two to three cups of coffee a day were roughly forty percent less likely to have erectile dysfunction than those who do not drink coffee. The scientists believe that the benefit comes from caffeine. The benefit works for men who are overweight or frankly obese as well as men with hypertension, common reasons for erectile dysfunction. The caffeine in coffee does not help if erectile dysfunction is causes by diabetes, but coffee itself can help prevent diabetes!
More Coffee Longer Lasting Erections
http://buyorganiccoffee.org/1391/more-coffee-linked-to-longer-lasting-erections/
And there is one more benefit of regular and healthy organic coffee. More coffee is linked to longer lasting erections! Forbes reports on a study published in the journal PLOS ONE. Coffee consumption is linked to decreased erectile dysfunction. That is to say if a man drinks more coffee he is more likely to be able to maintain an erection for the time desired.
According to a new study out in the journal PLOS ONE, caffeine intake is linked to reduced odds of having erectile dysfunction (ED) in men who drink the equivalent of two to three cups of coffee per day. Among the lifestyle factors that are known to put a man at risk of ED - poor diet, physical inactivity, smoking, and alcohol consumptions - caffeine has not been of the biggest candidates. But the new study suggests that like other areas of physical and mental health, ED may be another beneficiary of caffeine’s fascinating benefits. Since erectile function, and dysfunction, is in some ways an extension of cardiovascular health - and caffeine is known to have certain cardiovascular benefits - the idea that it could also help ED may not be so surprising. But for men who are devout coffee drinkers, the results may come as good news.
The odds of a man having difficulty maintaining an erection for the desired length of time is about 44 percent for men age 40 and over. For men over 70 the incidence of erectile dysfunction is 70 percent. So, just how much does coffee help?
What Is the Benefit of Coffee?
Researchers found that the caffeine equivalent of two to three cups of coffee a day were roughly forty percent less likely to have erectile dysfunction than those who do not drink coffee. The scientists believe that the benefit comes from caffeine. The benefit works for men who are overweight or frankly obese as well as men with hypertension, common reasons for erectile dysfunction. The caffeine in coffee does not help if erectile dysfunction is causes by diabetes, but coffee itself can help prevent diabetes!
USANA Health Sciences... Discover Your True Health and True Wealth with the #1 rated Home Based Business Opportunity and represent a company with Integrity that you can be proud of :)
Hello, this product is to help to detox our heavy metal toxic in the body, by doing so it will resolve the problems below:
1.Mental Emotional Issues – Depression
2.Back Pain, and other pain in the body
3.Diabetic
4.Fibroid
5.Autism
6.Stroke
7.Cancer
8.Parkinsons
i have the testimonial, kindly contact miketan9900@yahoo.com.sg for further information.
cheers
i am sorry, please forgive me, thank you, and i love you.
Less Ringing in Your Ears with Coffee
http://buyorganiccoffee.org/1205/less-ringing-in-your-ears-with-coffee/
There are all sorts of wonder health benefits from drinking coffee, especially healthy organic coffee. Now there is another benefit. It appears that you get less ringing in your ears with coffee consumption. This info comes from a prospective study derived from the Nurses’ Health Study II. Nurses’ Health Study II
was established by Dr. Walter Willett and colleagues in 1989 with funding from the National Institutes of Health. The primary motivation for developing the Nurses’ Health Study II was to study oral contraceptives, diet and lifestyle risk factors in a population younger than the original Nurses’ Health Study cohort.
Over the years a wealth of useful information has come from follow-ups on this group.
Less Ringing in Your Ears with Coffee
According to info published by the researchers in Nurses’ Health Study II, caffeine was originally thought to cause tinnitus, also called ringing in the ears. In order to test this hypothesis the researchers looked at the reports from 65,085 women aged 30 to 44 in the study group as of 1991. Information regarding ringing in the ears, tinnitus, was obtained from 2009 reports. Eighteen years after the initial baseline info was obtained more than 5000 women reported some degree of ringing in the ears. Interestingly the relationship to drinking coffee was opposite what common wisdom had predicted. Women who reported drinking two and three cups of coffee day had a significantly lower incidence of this condition that women who drank a cup of coffee a day or less. The conclusion of the report was that women who drink coffee have a lower incidence of ringing in the ears that those who do not. The study did not include men and did not address organic versus regular coffee.
One More Good Reason to Drink Coffee
This is just one more good reason to drink coffee. We have reported on these pages how coffee reduces the risk of type II diabetes, prostate cancer, endometrial cancer and colon cancer. Scientific evidence indicates that drinking coffee reduces your risk getting Alzheimer’s disease, Parkinson’s disease, depression or cirrhosis of the liver. We even noted that coffee may make sex better!
Do you know getting sufficient sleep is the key to a healthy lifestyle? Read on to find why sleep is so essential for your health and how much sleep you should be getting each night.
Au-delà des nombreux bienfaits de la consommation à dose faible ou modérée, les conclusions de l'étude précisent que les effets indésirables pour les adultes (anxiété, agitation, insomnie, rythme cardiaque, etc.), qui n'ont pas de complexités de santé, pourraient intervenir à partir d'une consommation de 400 mg de caféine par jour. Cette dose étant réduite à 200 mg pour les femmes enceintes ou allaitantes.
L'étude n'aborde pas le sujet de l’acrylamide, substance chimique qui a poussé en 2018 l'Etat de Californie à adopter une législation stipulant que le café devait porter une étiquette d'avertissement sur le cancer.
Coffee is one of the most traded commodity in the world, next only to oil. Undeniably, it is the most favorite beverage of the people. It is so irresistible that large section of people are addicted to it. Often, this addiction is seen in negative light and considered hazardous to one's health.
Come discover the amazing health benefits of being addicted to coffee. It is nothing less than miraculous.
USANA Health Sciences... Discover Your True Health and True Wealth with the #1 rated Home Based Business Opportunity and represent a company with Integrity that you can be proud of :)
Hello, this product is to help to detox our heavy metal toxic in the body, by doing so it will resolve the problems below:
1.Mental Emotional Issues – Depression
2.Back Pain, and other pain in the body
3.Diabetic
4.Fibroid
5.Autism
6.Stroke
7.Cancer
8.Parkinsons
i have the testimonial, kindly contact miketan9900@yahoo.com.sg for further information.
cheers
i am sorry, please forgive me, thank you, and i love you.
Less Ringing in Your Ears with Coffee
http://buyorganiccoffee.org/1205/less-ringing-in-your-ears-with-coffee/
There are all sorts of wonder health benefits from drinking coffee, especially healthy organic coffee. Now there is another benefit. It appears that you get less ringing in your ears with coffee consumption. This info comes from a prospective study derived from the Nurses’ Health Study II. Nurses’ Health Study II
was established by Dr. Walter Willett and colleagues in 1989 with funding from the National Institutes of Health. The primary motivation for developing the Nurses’ Health Study II was to study oral contraceptives, diet and lifestyle risk factors in a population younger than the original Nurses’ Health Study cohort.
Over the years a wealth of useful information has come from follow-ups on this group.
Less Ringing in Your Ears with Coffee
According to info published by the researchers in Nurses’ Health Study II, caffeine was originally thought to cause tinnitus, also called ringing in the ears. In order to test this hypothesis the researchers looked at the reports from 65,085 women aged 30 to 44 in the study group as of 1991. Information regarding ringing in the ears, tinnitus, was obtained from 2009 reports. Eighteen years after the initial baseline info was obtained more than 5000 women reported some degree of ringing in the ears. Interestingly the relationship to drinking coffee was opposite what common wisdom had predicted. Women who reported drinking two and three cups of coffee day had a significantly lower incidence of this condition that women who drank a cup of coffee a day or less. The conclusion of the report was that women who drink coffee have a lower incidence of ringing in the ears that those who do not. The study did not include men and did not address organic versus regular coffee.
One More Good Reason to Drink Coffee
This is just one more good reason to drink coffee. We have reported on these pages how coffee reduces the risk of type II diabetes, prostate cancer, endometrial cancer and colon cancer. Scientific evidence indicates that drinking coffee reduces your risk getting Alzheimer’s disease, Parkinson’s disease, depression or cirrhosis of the liver. We even noted that coffee may make sex better!
Do you know getting sufficient sleep is the key to a healthy lifestyle? Read on to find why sleep is so essential for your health and how much sleep you should be getting each night.
Au-delà des nombreux bienfaits de la consommation à dose faible ou modérée, les conclusions de l'étude précisent que les effets indésirables pour les adultes (anxiété, agitation, insomnie, rythme cardiaque, etc.), qui n'ont pas de complexités de santé, pourraient intervenir à partir d'une consommation de 400 mg de caféine par jour. Cette dose étant réduite à 200 mg pour les femmes enceintes ou allaitantes.
L'étude n'aborde pas le sujet de l’acrylamide, substance chimique qui a poussé en 2018 l'Etat de Californie à adopter une législation stipulant que le café devait porter une étiquette d'avertissement sur le cancer.
Coffee is one of the most traded commodity in the world, next only to oil. Undeniably, it is the most favorite beverage of the people. It is so irresistible that large section of people are addicted to it. Often, this addiction is seen in negative light and considered hazardous to one's health.
Come discover the amazing health benefits of being addicted to coffee. It is nothing less than miraculous.
The obesity epidemic in the United States can be blamed on a number of factors; A sedentary lifestyle, poor diet, lack of physical activity and sugaring soda drinks. It's cheap, addictive and readily available. Soda accounts for between 11 and 19 percent of calories consumed worldwide. Before you take another drink consider the facts concerning sugar laden soda pop.
Presentation during the Bureau of Agricultural Research (BAR) Seminar Series on January 26, 2017 at RDMIC Bldg., cor. Visayas Ave., Elliptical Rd., Diliman, Quezon City
Ang Chong Yi Navigating Singaporean Flavors: A Journey from Cultural Heritage...Ang Chong Yi
In the heart of Singapore, where tradition meets modernity, He embarks on a culinary adventure that transcends borders. His mission? Ang Chong Yi Exploring the Cultural Heritage and Identity in Singaporean Cuisine. To explore the rich tapestry of flavours that define Singaporean cuisine while embracing innovative plant-based approaches. Join us as we follow his footsteps through bustling markets, hidden hawker stalls, and vibrant street corners.
Piccola Cucina is regarded as the best restaurant in Brooklyn and as the best Italian restaurant in NYC. We offer authentic Italian cuisine with a Sicilian touch that elevates the entire fine dining experience. We’re the first result when someone searches for where to eat in Brooklyn or the best restaurant near me.
Key Features of The Italian Restaurants.pdfmenafilo317
Filomena, a renowned Italian restaurant, is renowned for its authentic cuisine, warm environment, and exceptional service. Recognized for its homemade pasta, traditional dishes, and extensive wine selection, we provide a true taste of Italy. Its commitment to quality ingredients and classic recipes has made it a adored dining destination for Italian food enthusiasts.
At Taste Of Middle East, we believe that food is not just about satisfying hunger, it's about experiencing different cultures and traditions. Our restaurant concept is based on selecting famous dishes from Iran, Turkey, Afghanistan, and other Arabic countries to give our customers an authentic taste of the Middle East
Roti Bank Hyderabad: A Beacon of Hope and NourishmentRoti Bank
One of the top cities of India, Hyderabad is the capital of Telangana and home to some of the biggest companies. But the other aspect of the city is a huge chunk of population that is even deprived of the food and shelter. There are many people in Hyderabad that are not having access to
Roti Bank Hyderabad: A Beacon of Hope and Nourishment
Coughlin_Caffeine Safety at 25th ASIC, Armenia, Colombia, Sept 9 2014
1. Caffeine Safety Review over Three Decades: Is the Increased Concern Justified?
James R. Coughlin, PhD CFS
President, Coughlin & Associates
Aliso Viejo, California
jrcoughlin@cox.net
www.linkedin.com/in/jamescoughlin
25th International Conference on
Coffee Science
Armenia, Colombia
September 9, 2014
3. Agenda
•
Caffeine & Health Issues -My Historical Perspective since 1981
•
Caffeine Issues in 2013-2014…
•
Coffee is NOT Just Caffeine
•
Energy Drinks & Other Foods / Beverages
•
Coffee is still the #1 Source of Caffeine
•
U.S. Congress & FDA, Health Canada, EFSA
•
Cardiovascular Issues are Key
3
4.
5.
6. “Caffeinated” -Journalist Murray Carpenter (2014)
“Making stops at the coffee farms of central Guatemala, a synthetic caffeine factory in China, and an energy shot bottler in New Jersey, among numerous other locales around the globe, Caffeinatedexposes thehigh-stakesbut murkyworld of caffeine, drawing on cutting-edge science and larger-than-life characters to offer an unprecedented understanding of America’s favorite drug.”
7. My 30+ Year Perspective on Caffeine / Health
…on Rats, Mice & Humans and Almost Every Disease
…on “Good” & “Bad” Science, Policy & Media Coverage
…on Caffeine’s BeneficialHealth Effects
… First 20 Years: Much Bad News! Caffeine was linked to many animal toxicities and human diseases!
… Last 15 or so Years…Very Big Turn Around: “Good News” is that almost all of the Bad News about caffeine was WRONG!
7
8. Caffeine’s “Maligning” Started in 1970’s and Ballooned in the 1980’s and Early 1990’s
•
Coffee and heart attacks…was it the caffeine?
•
Caffeine and birth defects in rats (U.S. FDA, 1978); hundreds of subsequent studies on reproductive & developmental effects in humans
•
Caffeine and urinary calcium loss; osteoporosis risk?
•
Central Nervous System: anxiety, sleep disturbance, “addiction”?
8
9.
10. What Science Allowed the Bad Myths to Happen and Why Do a Few Still Persist?
… Acute vs. Chronic effects:
Partial / full tolerance to caffeine develops in humans consistently consuming caffeine and coffee daily
… Most of the Myths and Fears are based on:
Acute effects testing of non-caffeine consuming subjects
Massive doses of caffeine fed to pregnant animals
Smaller, poorly done and not well controlled human studies. 10
11. But since 2000 or so…
The “Good News” is that almost all of the earlier bad news about coffee and caffeine was WRONG!
Medical evidence has been building strongly that coffee and caffeine may actually be GOOD for us!!!
Let’s briefly examine the evidence for some of the myths and facts. 11
13. “Beverage Caffeine Intakes in the U.S.”
•
96% of beverage caffeine consumed from coffee, soft drinks and tea; Coffeeremains the largest contributor
•
Energy drinks & shots and chocolate beverages contribute littleto caffeine intakes
•
Teenagers (13-17 years) or young adults (18-24 years) - 9-10%of their caffeine comes from energy drinks
•
Intakes from energy drinks represent less than 2%of totaldaily mean caffeine values for all caffeinated beverage consumers.
Sponsor: International Life Sciences Institute
13
15. Caffeine and Reproductive Effects
•
Issue first began with birth defects (missing toes) in rats force-fed by stomach tube with very high-dosesof caffeine (FDA, 1978)
•
But no adverse effects were seen in FDA’s follow-up “sipping” study of the same high doses
•
Human studiesfollowed: delayed conception, premature birth. low birth weight babies, fetal death, spontaneous abortion (miscarriage), congenital birth defects
•
But now there are more than 25 published reviews supporting caffeine’s safety.
15
19. Caffeine and “Addiction”
•
Dependence, tolerance and withdrawal headache were cited in many published studies going back to the late 1980’s (but mostly among psychiatric patients consuming up to 20 cups/day)
•
Current view is very reassuring:
•
Caffeine use was notclassified as a “substance use disorder” (the new term for addiction) in the American Psychiatric Assn’s DSM-5 “bible” (published May 2013)
•
However, DSM-5 did recognize caffeine intoxication and withdrawal disorders
•
Addiction over-warningstrivialize dangers of realdrugs of abuse.
19
20. Caffeine and Osteoporosis
•
Excess calcium loss & bone loss in post-menopausal womencauses millions of bone fractures (mostly hip)
•
Acute, 24-hour human studies done in the 1980’s on non-caffeine consumingsubjects were originally misinterpreted
•
Many longer-term, human clinical studies have since shown littleexcess calcium or bone loss and noincreased risk of osteoporosis.
20
21. Coffee/Caffeine and Cancer Risk
•
Coffee contains trace levels of animalcarcinogens produced by heat in the “Maillard Browning Reaction,” including acrylamide and furan
•
Over 550 human epidemiology studies have been published since the 1970’s on many human organs
•
Most health authorities across the globe now agree that coffee drinking (and caffeine) is NOTa cancer risk, and coffee may actually reduce the risk of numerous cancers
•
I have termed this the “Coffee-Cancer Paradox”
21
22. Summary Conclusions on the “Bad” Health Effects
•
Long established history of safeglobal caffeinated coffee consumption (and decaffeinated as well)
•
But more animal, clinical & epidemiologic studies will be published, and continued media attention is sure to come
•
More recentstudies and re-examinations of older disease issues have been quite reassuring
•
Consumers can be assured that their health will notbe adversely affected by the enjoyment of coffee and caffeine as currently consumed.
22
23. Caffeine’s Beneficial Physiological Effects
•
Mild central nervous system (CNS) stimulant
•
Improves cognitiveperformance and mental processing; increases wakefulness;improvesworkperformance and enhances mood
•
Increases capacity for physicalwork & exercise; improves muscular performance and endurance sports
•
Relaxes smooth muscle, especially bronchial (opens airways), and increases blood flowin heart and kidneys
•
Produces a slightly higher metabolic rate(some evidence of an ergogenic “fat burning” effect)
•
Riskreductionsfor Parkinson’s & Alzheimer’s diseases, depression & suicide.
23
24. So with all this more recent goodnews, why are we still worrying about Caffeine? New safety concerns have been raised for Energy Drinksand new food products containing addedCaffeine
24
27. Very Recent Studies / Reviews on Concerns over Energy Drinks… …done by researchers who do notknow the 30+ years of caffeine literature…on hypertension, arrhythmias, heart attacks, strokes, reduced mortality
27
36. FDA Statement on Wrigley’s “Alert Energy” Caffeine Gum Withdrawal (May 2013)
Michael R. Taylor, FDA Deputy Commissioner for Foods & Vet. Medicine:
Wrigley (a subsidiary of Mars) announced its decision to pause production, sales, and marketing of Alert Energy Caffeine Gum. This announcement was made following a series of discussions with the FDA in which the agency expressed concerns about caffeine appearing in a range of new foods and beverages.
The FDA applauds Wrigley’s decision and its recognition that we need to improve understanding and, as needed, strengthen the regulatory framework governing the appropriate levels and uses of caffeine in foods and beverages. The company’s action demonstrates real leadership and commitment to the public health.
We hope others in the food industry will exercise similar restraint. We look forward to working with industry, the scientific and medical community, and all interested parties to address the issues posed by added caffeine in foods and beverages.
36
39. My U.S. Senate Oral Testimony
1.
The caffeine content in energy drinks is equivalentto that of an equal amount of coffee, and less than that of coffeehouse coffees.
2.
The health outcomes of caffeine consumption have been thoroughly studied for decades, and the best available scientific & clinical evidence does not support the idea that caffeine should be prohibited (and certainly not a single source of caffeine).
3.
Coffee, tea and soda are the primary sources of caffeine in U.S. diets, including diets of children and teens. Current exposure assessments conducted by the FDA indicate that caffeine consumption by children and youth is not a safety concern. 39
41. IOM Workshop Objectives Set by FDA
•
Evaluate the epidemiological, toxicological, clinicaland other relevant
literature to describe important health hazards associated with caffeine
consumption from ALLfoods and beverages.
•
Delineate vulnerable populationswho may be at risk from caffeine exposure.
•
Describe the possible risk of caffeine’s cardiovascular and other health effects, including additive effectswith other ingredients and effects related to preexistingconditions.
•
Explore safe caffeine exposure levelsfor general and vulnerable populations.
•
Identify data gapson caffeine stimulant effects, including but not limited to cardiovascular, central nervous system, or other health outcomes.
41
45. European Food Safety Authority (EFSA)
•
Zucconiet al., 2013. “Gathering consumption data on specific consumer groups of energy drinks.” [190 pages] www.efsa.europa.eu/publications
•
EFSA opinion on caffeine’s safety was requested by the EC (Feb 2013); established a Working Group on Caffeine…
•
Maximum levels of caffeine intake from all sources
•
Risk of interaction of caffeine with alcohol and other ingredients of “Energy Drinks”
•
Focus: general population, adults performing physical activities of various intensities, pregnant & lactating women, children & adolescents
•
Several meetings of the Scientific Panel on Dietetic Products, Nutrition and Allergies (NDA Panel)
•
Draft Opinion will issue early November,public consultation for 6-8 weeks, adoption by Spring 2015. 45
47. “Food additives on the rise as FDA scrutiny wanes” Washington Post, August 17, 2014
•
“The explosion of new food additives coupled with an easing of oversight requirements is allowing manufacturers to avoid the scrutiny of the FDA, which is responsible for ensuring the safety of chemicals streaming into the food supply.”
•
“We simply do not have the information to vouch for the safety of many of these chemicals,” said Michael Taylor, the FDA’s Deputy Commissioner for Food.
•
“Within the past six months, top officials at the FDA and in the food industry have acknowledged that new steps must be taken to better account for the additives proliferating in the food supply.”
•
“This is what happened with caffeine. In 1959, the FDA approved it as GRAS, allowing soft drink manufacturers to add it to their products. But now food manufacturers are loading caffeine into energy drinks, maple syrup, jelly beans and marshmallows.”
51. “Tolerance to the Humoral and Hemodynamic Effects of Caffeine in Man” –Vanderbilt University’s David Robertson (1981)
•
Previous studies showed acute caffeine given to caffeine-naïvesubjects increased BP, heart rate, plasma epinephrine & norepinephrine, plasma renin activity and urinary catecholamines
•
Robertson did a double-blind study of the effects of chroniccaffeine administration on these same variables
•
Demonstrated that near complete tolerancefor both the humoral and hemodynamic variables developed over the first 1-4 days of caffeine intake
•
Showed no long term adverse effectsof caffeine on BP, heart rate, plasma renin activity, plasma catecholamines, or urinary catecholamines. 51
59. Take Home Messages… ~ Attackers should understand the Caffeine literature beforethey accuse it as the causative agent! ~ Caffeine in coffee & other foods and beverages is safefor human consumption!
59