This case study describes the treatment of a patient with severe recession and compromised esthetics of the upper front teeth. A multidisciplinary treatment plan was developed involving periodontal plastic surgery using an acellular dermal graft for root coverage, followed by prosthetic rehabilitation with crowns. The surgery involved grafting and tissue shaping to improve the gingival contours. After healing, crowns were placed on teeth #6-10 to improve esthetics and function. The final result achieved the patient's goal of enhanced appearance with minimal time and cost.
#News43: Young Clinicians Clinical Case Competition at the 3rd MIS Global Con...José Luis Pimentel
During the first day of the 3rd MIS Global Conference,
more than 300 people attended the young clinicians'
case competition session where 5 doctors were invited to
present their cases.
Chairing the event was Professor Gabi Chaushu, head of
the Department of Oral & Maxillofacial Surgery at the Rabin
Medical Center in Israel.
Out of the 49 cases submitted for review, the scientific
committee, which included Professor Stefen Koubi, Professor
Nitzan Bichacho, Dr. Eric Van Dooren and Professor Moshe
Goldstein, chose the finalists out of which these 3 winners
were ultimately chosen.
IMMEDIATE LOADING WITH MINI DENTAL IMPLANTS IN THE FULLY EDENTULOUS MANDIBLEAbu-Hussein Muhamad
Mini dental implants (MDI) have become increasingly popular in the past decade and have been approved for many long-term uses in dentistry. There are many advantages of the use of mini dental implants from both a practitioner and patient perspective. For the general dentist starting out in implant dentistry, their placement can be more challenging than conventional implants. It requires a different skill set, but one which can be learned with proper guidance and practice.In the study are presented clinical cases with mini implants with spherical joints for retention of removable overimplant mandibular dentures.
Key words: mini dental implants, immediate loading implants Prosthetics, overdenture
#News43: Young Clinicians Clinical Case Competition at the 3rd MIS Global Con...José Luis Pimentel
During the first day of the 3rd MIS Global Conference,
more than 300 people attended the young clinicians'
case competition session where 5 doctors were invited to
present their cases.
Chairing the event was Professor Gabi Chaushu, head of
the Department of Oral & Maxillofacial Surgery at the Rabin
Medical Center in Israel.
Out of the 49 cases submitted for review, the scientific
committee, which included Professor Stefen Koubi, Professor
Nitzan Bichacho, Dr. Eric Van Dooren and Professor Moshe
Goldstein, chose the finalists out of which these 3 winners
were ultimately chosen.
IMMEDIATE LOADING WITH MINI DENTAL IMPLANTS IN THE FULLY EDENTULOUS MANDIBLEAbu-Hussein Muhamad
Mini dental implants (MDI) have become increasingly popular in the past decade and have been approved for many long-term uses in dentistry. There are many advantages of the use of mini dental implants from both a practitioner and patient perspective. For the general dentist starting out in implant dentistry, their placement can be more challenging than conventional implants. It requires a different skill set, but one which can be learned with proper guidance and practice.In the study are presented clinical cases with mini implants with spherical joints for retention of removable overimplant mandibular dentures.
Key words: mini dental implants, immediate loading implants Prosthetics, overdenture
International Journal of Engineering and Science Invention (IJESI) is an international journal intended for professionals and researchers in all fields of computer science and electronics. IJESI publishes research articles and reviews within the whole field Engineering Science and Technology, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Intentional replantation of maxillary second molar; case report and 15-year f...Abu-Hussein Muhamad
Abstract: Intentional reimplantation is a procedure in which tooth extraction is performed followed by reinsertion of the extracted tooth into its own socket after performing the desired procedure. In this article, intentional reimplantation is described and discussed as a treatment approach for aperiapical lesion that is in maxillary second molar. After 15 years, the patient was asymptomatic, the tooth was still functional and a recall intraoral periapical radiograph showed an intact periodontal ligament space and lamina dura with no evidence of gross root resorption or ankylosis.
Keywords: Intentional replantation, calcified canals, mineral trioxide aggregate
JOURNAL CLUB: Terminology of Dental Caries and Dental Caries Management: Cons...Urvashi Sodvadiya
Vita Machiulskienea, Guglielmo Campusb, c Joana Christina, Carvalhod Irene, Digee Kim, Rud Ekstrandf, Anahita Jablonski-Momenig, Marisa Maltzh, David J. ,Mantoni Stefania, Martignonj, k E. Angeles, Martinez-Mierl, Nigel B., Pittsj Andreas G., Schultem Christian, H. Spliethn, Livia Maria, Andaló Tenutao, Andrea Ferreira Zandonap, Bente Nyvade
CARIES RESEARCH; OCT 2019
An Interdisciplinary Approach for Improved Esthetic Results in the Anterior M...Abu-Hussein Muhamad
Maxillary midline diastema is usually the part of normal dental development during mixed dentition which requires no active treatment. But the continuing presence of it in an adult is an esthetic problem. The effective treatment of midline diastema depends on the etiological factors, size andextent of diastema. This clinical report describes a patient with uneven interdental space between anterior maxillary teeth, improper clinical crown lengths, tooth size discrepancies, and malocclusion. Key words: Diastema closure, midline diastema, Orthodontic treatment, Porcelain laminate veneers, Interdisciplinary approach
“Comparative Evaluation between Physics Forceps and Conventional Extraction F...inventionjournals
:Tooth extraction procedure, although known as a minimal traumatic procedure, some sort of trauma is subjected to underlying soft and hard tissues, resulting in immediate destruction and loss of alveolar bone. Conventional extraction forceps are designed on the principle of simple machine incorporating two first-class levers, connected with a hinge. The physics forceps are the newly invented forceps. The design of physics forceps which implements a first class lever, creep, and type of force that provides a mechanical advantage, which makes it more efficient. AIM: The aim of the present study to evaluate the efficacy between the conventional extraction forceps and physics forceps in orthodontic extraction of maxillary premolars. Patients & Methods:A total of 50 healthy patients with indicated for extraction of bilateral maxillary premolar for orthodontic reasons; split mouth design (control side, test side) in a randomized manner; were included in the present study. Results:Ease of technique, buccal cortical plate fracture, fracture of tooth or root, gingival laceration, soft tissue healing was not significant. The extraction time and bleeding associated with extraction socket were significant. Post operative days 1-4 are not significant and on day 5-7 the pain on VAS score is 0. Conclusion:The results of present study suggest that, extraction using any forceps can produce predictable results and it totally depends on surgeon’s expertise in a particular technique.
Partial or complete edentulism has multiple implications in relation to function, esthetics and future rehabilitative treatment. This case report illustrates the management of a patient with extreme consequences of partial edentulism in the maxillary arch and total edentulism in the mandibular arch. The main clinical findings were unopposed remaining teeth, over eruption of the remaining teeth, loss of vertical dimension of occlusion, and significant disfigurement of the occlusal plane. Following the diagnostic procedure, a well-coordinated prosthodontic treatment involving liaison with other dental disciplines was indicated. The management involved an innovative combination of fixed and removable prostheses in conjunction with intentional root canal therapy of the remaining natural teeth. Series of provisional prostheses were applied to facilitate the transition to the final treatment.
Key-words: Edentulism, Vertical dimension, Provisional Restoration, Fixed and Removable prosthesis
Short term and long-term stability of surgically assisted rapid palatal expan...Dr Sylvain Chamberland
Introduction: The purpose of this article is to present further longitudinal data for short-term and long-term
stability, following up our previous article in the surgery literature with a larger sample and 2 years of stability
data. Methods: Data from 38 patients enrolled in this prospective study were collected before treatment, at maximum
expansion, at removal of the expander 6 months later, before any second surgical phase, at the end of
orthodontic treatment, and at the 2-year follow-up, by using posteroanterior cephalograms and dental casts.
Results: With surgically assisted rapid palatal expansion (SARPE), the mean maximum expansion at the first
molar was 7.60 6 1.57 mm, and the mean relapse was 1.83 6 1.83 mm (24%). Modest relapse after completion
of treatment was not statistically significant for all teeth except for the maxillary first molar (0.99 6 1.1 mm). A
significant relationship (P-.0001) was observed between the amount of relapse after SARPE and the posttreatment
observation. At maximum, a skeletal expansion of 3.58 6 1.63 mm was obtained, and this was stable.
Conclusions: Skeletal changes with SARPE were modest but stable. Relapse in dental expansion was almost
totally attributed to lingual movement of the posterior teeth; 64% of the patients had more than 2 mm of dental
changes. Phase 2 surgery did not affect dental relapse.
Are you a communal or lay leader? Are you raising funds for charity? Would you like to promote a cause? Or maybe worried about your organisation's reputation? In this session, I will be going through the various ways you can use Facebook, Twitter, and Youtube to raise your profile, grow your audience and ultimately promote your cause.
International Journal of Engineering and Science Invention (IJESI) is an international journal intended for professionals and researchers in all fields of computer science and electronics. IJESI publishes research articles and reviews within the whole field Engineering Science and Technology, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Intentional replantation of maxillary second molar; case report and 15-year f...Abu-Hussein Muhamad
Abstract: Intentional reimplantation is a procedure in which tooth extraction is performed followed by reinsertion of the extracted tooth into its own socket after performing the desired procedure. In this article, intentional reimplantation is described and discussed as a treatment approach for aperiapical lesion that is in maxillary second molar. After 15 years, the patient was asymptomatic, the tooth was still functional and a recall intraoral periapical radiograph showed an intact periodontal ligament space and lamina dura with no evidence of gross root resorption or ankylosis.
Keywords: Intentional replantation, calcified canals, mineral trioxide aggregate
JOURNAL CLUB: Terminology of Dental Caries and Dental Caries Management: Cons...Urvashi Sodvadiya
Vita Machiulskienea, Guglielmo Campusb, c Joana Christina, Carvalhod Irene, Digee Kim, Rud Ekstrandf, Anahita Jablonski-Momenig, Marisa Maltzh, David J. ,Mantoni Stefania, Martignonj, k E. Angeles, Martinez-Mierl, Nigel B., Pittsj Andreas G., Schultem Christian, H. Spliethn, Livia Maria, Andaló Tenutao, Andrea Ferreira Zandonap, Bente Nyvade
CARIES RESEARCH; OCT 2019
An Interdisciplinary Approach for Improved Esthetic Results in the Anterior M...Abu-Hussein Muhamad
Maxillary midline diastema is usually the part of normal dental development during mixed dentition which requires no active treatment. But the continuing presence of it in an adult is an esthetic problem. The effective treatment of midline diastema depends on the etiological factors, size andextent of diastema. This clinical report describes a patient with uneven interdental space between anterior maxillary teeth, improper clinical crown lengths, tooth size discrepancies, and malocclusion. Key words: Diastema closure, midline diastema, Orthodontic treatment, Porcelain laminate veneers, Interdisciplinary approach
“Comparative Evaluation between Physics Forceps and Conventional Extraction F...inventionjournals
:Tooth extraction procedure, although known as a minimal traumatic procedure, some sort of trauma is subjected to underlying soft and hard tissues, resulting in immediate destruction and loss of alveolar bone. Conventional extraction forceps are designed on the principle of simple machine incorporating two first-class levers, connected with a hinge. The physics forceps are the newly invented forceps. The design of physics forceps which implements a first class lever, creep, and type of force that provides a mechanical advantage, which makes it more efficient. AIM: The aim of the present study to evaluate the efficacy between the conventional extraction forceps and physics forceps in orthodontic extraction of maxillary premolars. Patients & Methods:A total of 50 healthy patients with indicated for extraction of bilateral maxillary premolar for orthodontic reasons; split mouth design (control side, test side) in a randomized manner; were included in the present study. Results:Ease of technique, buccal cortical plate fracture, fracture of tooth or root, gingival laceration, soft tissue healing was not significant. The extraction time and bleeding associated with extraction socket were significant. Post operative days 1-4 are not significant and on day 5-7 the pain on VAS score is 0. Conclusion:The results of present study suggest that, extraction using any forceps can produce predictable results and it totally depends on surgeon’s expertise in a particular technique.
Partial or complete edentulism has multiple implications in relation to function, esthetics and future rehabilitative treatment. This case report illustrates the management of a patient with extreme consequences of partial edentulism in the maxillary arch and total edentulism in the mandibular arch. The main clinical findings were unopposed remaining teeth, over eruption of the remaining teeth, loss of vertical dimension of occlusion, and significant disfigurement of the occlusal plane. Following the diagnostic procedure, a well-coordinated prosthodontic treatment involving liaison with other dental disciplines was indicated. The management involved an innovative combination of fixed and removable prostheses in conjunction with intentional root canal therapy of the remaining natural teeth. Series of provisional prostheses were applied to facilitate the transition to the final treatment.
Key-words: Edentulism, Vertical dimension, Provisional Restoration, Fixed and Removable prosthesis
Short term and long-term stability of surgically assisted rapid palatal expan...Dr Sylvain Chamberland
Introduction: The purpose of this article is to present further longitudinal data for short-term and long-term
stability, following up our previous article in the surgery literature with a larger sample and 2 years of stability
data. Methods: Data from 38 patients enrolled in this prospective study were collected before treatment, at maximum
expansion, at removal of the expander 6 months later, before any second surgical phase, at the end of
orthodontic treatment, and at the 2-year follow-up, by using posteroanterior cephalograms and dental casts.
Results: With surgically assisted rapid palatal expansion (SARPE), the mean maximum expansion at the first
molar was 7.60 6 1.57 mm, and the mean relapse was 1.83 6 1.83 mm (24%). Modest relapse after completion
of treatment was not statistically significant for all teeth except for the maxillary first molar (0.99 6 1.1 mm). A
significant relationship (P-.0001) was observed between the amount of relapse after SARPE and the posttreatment
observation. At maximum, a skeletal expansion of 3.58 6 1.63 mm was obtained, and this was stable.
Conclusions: Skeletal changes with SARPE were modest but stable. Relapse in dental expansion was almost
totally attributed to lingual movement of the posterior teeth; 64% of the patients had more than 2 mm of dental
changes. Phase 2 surgery did not affect dental relapse.
Are you a communal or lay leader? Are you raising funds for charity? Would you like to promote a cause? Or maybe worried about your organisation's reputation? In this session, I will be going through the various ways you can use Facebook, Twitter, and Youtube to raise your profile, grow your audience and ultimately promote your cause.
How social networks can help build client relationships within the healthcare...Brainstorm Digital
- Using Linkedin groups to seek out new clients and referrers
- How LinkedIn discussions can be used to develop new relationships
- Growing your LinkedIn network in order to gain access to new clients and markets
- Using Twitter to gain access to senior managers as well as thought leaders in the healthcare industry
How charities can generate a sustainable income from social mediaBrainstorm Digital
How to leverage social media to dramatically increase your charity’s income.
* Optimising your LinkedIn profile so you're highly visible to influencers and other key figures who'll promote your charity
* Connecting with influencers and converting them into your advocates
* Leveraging your LinkedIn contacts in order to get introduced to major donors
* How to share high quality content that will help advocates advance your cause
* Using LinkedIn groups to extend your influence and reach out to new contacts
Autogenous tooth fragment reattachment ; a 12 years follow-upAbu-Hussein Muhamad
The fractures of the anterior teeth are a common form of dental trauma that mainly affects children and adolescents. One of the therapeutic options for managing coronal tooth fractures when the tooth fragment is available and there is no or minimal violation of the biological width is the Autogenous reattachment of the dental fragment.. Reattachment of fractured fragment can provide good and long lasting esthetics. This is a report of a 12 -year follow-up of a coronal fracture case successfully treated using tooth fragment reattachment.
Keywords: Composite resins, coronal fracture, fragment reattachment
Fabrication of Complete Dentures for A Patient with Resorbed Mandibular Anter...QUESTJOURNAL
ABSTRACT: The loose and unstable lower complete denture is one of the most common problems faced by denture patients with highly resorbed ridge. The management of such highly resorbed ridges has always posed a difficulty to the prosthodontist.Obtaining consistent mandibular denture stability has longbeen a challenge for dental profession. The simplest approach often is to extend the denture base adequately for proper use of all available tisues.To achieve this goal impression of the resorbed mandibular ridge is very important. The objective is to develop a physiologic impression with maximum support of both hard and soft tissues.In such cases, an innovative technique of impressionmaking by using a close fitting tray and anelastomeric impression material tomake a proper impression to achieve maximum retentionand stability.This article describes an impression technique used for highly resorbed mandibular ridge using an all green impression technique, to gain maximum retention andstability
Clinical Replacement Therapy and the Immediate Post-extraction Dental ImplantAbu-Hussein Muhamad
Immediate dental implants have greatly reduced the treatment time and the number of surgical intervene tions. Recently it has been noted that this treatment modality can be used in aesthetically demanding cases especially the anterior maxilla. The aim of this article is to describe a clinical case in which a fractured maxillary canine was replaced by an osseointegrated implant using a simplified technique in a patient who was a smoker and presented poor oral hygiene. The technique adopted permits a reduction of the number of implant components and consequently a lower cost of treatment, while at the same time maintaining acceptable aesthetic and functional outcomes.
Strip Crowns Technique for Restoration of Primary Anterior Teeth: Case ReportAbu-Hussein Muhamad
Dental caries is the single most common chronic childhood disease affecting worldwide. In early childhood caries, there is early pulp involvement and gross destruction of maxillary anterior teeth as well as posterior teeth. Treatment of such caries represents a challenge to pediatric dentists especially, when teeth are badly destroyed. By the time the dentist sees the child, most of the coronal structure is lost. This case report describes challenging task of a Case of early childhood caries patients with mutilated maxillary incisors restored with a strip form composite restorations.
Multidisciplinary Approach in the Rehabilitation of Congenitally Maxillary C...Abu-Hussein Muhamad
Objective: This case report describes the multidisciplinary
approach to treat a congenitally missed maxillary canine, how to
improve patient’s smile using orthodontic fixed appliance, endosseous
dental implant, and porcelain veneer to achieve the treatment results of
function and esthetic.
Materials and procedures: Unilateral agenesis of the permanent
maxillary canines in healthy individuals is extremely rare. This
paper presents the case of a female patient diagnosed with congenital
unilateral agenesis of the permanent maxillary canines as well as
occlusal abnormalities in the form of left-side crossbite. To restore the
proper aesthetics and function, interdisciplinary therapeutic treatment
was implemented. In the case presented in this paper, the aim of
oral rehabilitation was to restore a functional balance by obtaining
proper skeletal relationships, creating optimal occlusal conditions and
obtaining arch continuity.
Conclusion: Interdisciplinary treatment combined of orthodontics,
implant surgery, and prosthodontics was useful to treat a nonsyndromic
oligodontia patient. Especially, with the new strategy, implantanchored
orthodontics, which can facilitate the treatmentand make it
more simply with greater predictability.
Atrophied Edentulous Mandible with Implant-Supported Overdenture; A 10-year f...Abu-Hussein Muhamad
Abstract: Severe atrophy of the inferior alveolar process and underlying basal bone often results in problems with a lower denture. These problems include insufficient retention of the lower denture, intolerance to loading by the mucosa, pain, difficulties with eating and speech, loss of soft-tissue support, and altered facial appearance. These problems are a challenge for the prosthodontist and surgeon. In this case report, patient with resorbed edentulous mandible was successfully rehabilitated using two dental implants placed in the interforaminal region with ball abutments opposing conventional maxillary complete denture. Key Words: dental implants; dental prosthesis, implant-supported; resorption,
Atrophied Edentulous Mandible with Implant-Supported Overdenture; A 10-year f...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
1. CASE STUDY
Tri M. Le, DDS, FAGD
Complex Anterior Private Practice
Southeast Texas Cosmetic
Dentistry
Treatment Port Arthur, Texas
Phone: 409.982.7827
Email: tmldds@gt.rr.com
Web site:
A Case Report southeasttexascosmetic
dentistry. com
N
umerous innovations in den- sary radiographs, photographs, and After discussing the treatment
tal materials and techniques mounted models were taken and care- phases, costs, and time with the
have dramatically changed fully analyzed. In this treatment plan, patient, he was appointed for the peri-
modern dental practice. In addition, the the root of tooth No. 9 would be cov- odontal plastic surgery phase. After
predictability of dental implants and tis- ered with an acellular grafting materi- verbal review of the procedure and pre-
sue regeneration has greatly influenced al, Alloderm (BioHorizons, Inc), to medication (patient was to start taking
diagnosis and treatment planning. help correct the severe recession. The amoxicillin 875 mg b.i.d., 48 hours
Consequently, a clinician can be con- crown of tooth No. 7 would be length- before and dexamethasone 4 mg, 24
founded by the many valid treatment ened, and new crowns would be hours before), all consent forms were
options. Oftentimes, the selected treat- placed on teeth Nos. 6 (to emulate a given to the patient, reviewed, and
ment is based on financial factors, insur- lateral incisor), 7 (to mimic a central signed. The patient was then given two
ance coverage, and time as well as the incisor), 9, and 10, respectively. 200 mg tablets of ibuprofen and was
clinician’s training, comfort zone, and Before proceeding with any treat- instructed to rinse with chlorhexidine
available referral sources. This article ment, the patient was invited back for 0.12% for 60 seconds. Vital signs,
will illustrate one method of solving a an in-depth discussion of the expected including oxygen saturation, were
complex esthetic puzzle using periodon- outcome. The patient was informed taken and monitored with an electron-
tal plastic surgery to complement pros- that it would be impossible to achieve ic blood pressure monitor. The patient
thetic rehabilitation. an ideal result because teeth Nos. 6 was then draped for surgery with hair
and 7 had previously been reposi- cover and disposable gown. The peri-
Case Presentation tioned. Fortunately, the patient’s exist- oral area was then scrubbed with
A 50-year-old man of good overall ing low smile line would help mask chlorhexidine 0.12%. Following topi-
health presented to the office with a any final restorative imperfections. cal anesthesia, 4% Citanest Plain
complaint of the greatly compromised After careful analysis of the (Dentsply Pharmaceutical) was given
appearance of his upper anteriors patient’s gingival and osseous architec- for comfort and preliminary anesthesia.
(Figure 1). Examination revealed that ture, including information gathered Marcaine 0.5% with 1:200,000 epi-
tooth No. 8 was missing and tooth from probing depth records and radio- nephrine (Abbott Laboratories) was
No. 7 had a composite veneer to make graphs, a surgical guide was made then administered for more profound
it appear as a central incisor. In addi- from the diagnostic model to help anesthesia.
tion, tooth No. 9 had a severe facial with the soft-tissue surgical phase of The procedure was initiated with
periodontal defect (Figure 2). The the treatment. In cases such as this, a coronoplasty of the defective crown
patient stated that he was seeking to diagnostic model not only gives a on tooth No. 9 to allow full and pas-
improve his appearance with minimal glimpse of the eventual prosthodontic sive insertion of the clear surgical stent
cost in time and money, not a restorations, but also provides crucial so that an outline of the desired gingi-
“Hollywood smile.” information and guidance on the val margins on teeth Nos. 7 and 9
To arrive at a proper treatment desirable soft-tissue appearance at the could be visualized in situ. This step
plan in such a complex case, all neces- end of treatment. helped finalize how much crown
42 CONTEMPORARY ESTHETICS | SEPTEMBER 2007
2. CASE STUDY
Figure 1—Pretreatment smile view showing Figure 2—Pretreatment view showing severe Figure 3—Retracted view, flap elevated.
compromised appearance. facial perioesthetic defect.
Figure 4—Retracted view, Alloderm in place. Figure 5—Retracted view, flap re-approxi- Figure 6—Retracted view, 12 weeks after
mated and sutured. surgery, showing good healing.
lengthening would be needed on (Figure 4). The use of an acellular graft (Figure 5).10-12 Gauze soaked
tooth No. 7 and how much graft vol- dermal graft helps eliminate the with saline then was placed onto the
ume would be needed for tooth No. requirement for palatal donor tissue surgical area with light pressure for
9. After this, the gingivectomy was or other intraoral tissue harvesting. 15 minutes to help achieve initial sta-
carried out with a Bard-Parker blade This choice of graft material helps bilization and clotting.
No.15C (BD) on tooth No. 7. Then reduce chair time, thus avoiding The patient was slowly seated
the flap was reflected to ascertain the additional discomfort to the patient upright, and postoperative instruc-
location of the osseous crest of tooth and is, therefore, a useful method for tions were reviewed with special
No. 7, in case any osseous resection root coverage.2-9 The flap was then emphasis on rinsing with chlorhexi-
was necessary not to violate the bio- repositioned and evaluated for pas- dine 0.12% b.i.d. and warm salt
logic width. sivity with no tension when the inci- water as often as possible. In addi-
After the flap had been ade- sion lines were approximated. tion, a supply of microbrushes and
quately reflected to allow access to Additional reflection with scoring of instructions on their correct usage was
tooth No. 9 (Figure 3), the root was the periosteum ensured proper and given to the patient so that only a
scaled with hand instruments and tension-free flap coverage of the sur- microbrush soaked with chlorhexidine
then treated with citric acid. The gical area. The flap was then sutured 0.12% would be used in the surgical
acellular dermal graft material was with 5-0 vicryl (Ethicon, Inc). A sling area for the next 10 days when the
rehydrated for 10 minutes in a sterile suture with 6-0 gut also was added patient was scheduled for a postopera-
saline bath.1 After proper trimming, onto the facial marginal gingiva of tive check-up and suture removal.
the graft was placed in the surgical tooth No. 9 to further ensure graft After a waiting period of 3
site and adapted to the root of tooth immobilization, which is crucial for months for proper healing (Figures 6
No. 9 and adjacent crestal bone the survival and incorporation of the and 7), the patient was appointed for
44 CONTEMPORARY ESTHETICS | SEPTEMBER 2007
3. Figure 7—Occlusal view, 12 weeks after sur- Figure 8—Occlusal view of the preparations on Figure 9—Retracted view of provisional
gery, showing good tissue volume around teeth Nos. 6 through 10. Note the proper healing crowns on teeth Nos. 6 through 10.
tooth No. 9. of the graft and the esthetic complexity of case.
Figure 10—The final crowns on the model Figure 11—Palatal view of the crowns on the Figure 12—Full smile view, immediately after
showing the technician’s skill in compensating model. cementation.
for the size discrepancy between teeth Nos. 7
and 9.
the prosthetic treatment phase, during and anterior stick-bite impressions were Before the crowns were received
which teeth Nos. 6, 7, 9, and 10 were obtained. A facebow transfer also was from the laboratory, the patient
prepared for full crowns with the goal of acquired. The provisional crowns were requested to have his teeth bleached.
making tooth No. 6 resemble a lateral then cemented temporarily with Normally, this step is done before the
incisor and No. 7 look like a central inci- TempBond Clear (Kerr Corporation). crown preparation step, but at times,
sor (Figure 8). Retraction cords, Gingi- After the removal of excess cement and the clinician must work around the
BRAID 000 and 00 (Dux Dental), were the retraction cords, the occlusion was patient’s sudden desire. The patient was
packed for 10 minutes, the 00 cords were checked and adjusted with the patient appointed for in-office bleaching with
removed, and an impression was made seated upright. the Zoom! Advanced Power system
with a custom tray and a polyvinyl silox- The patient was appointed for a (Discus Dental). Alginate impressions
ane impression material (Imprint Garant, refinement visit, during which the pro- were made to fabricate at-home bleach-
3M ESPE). After a good impression had visionals were touched up. After the ing trays. While the patient’s teeth were
been obtained, the custom tray for the patient had approved the fit and being whitened in-office, the impres-
fabrication of the provisional crowns was appearance of the provisional crowns, sions were poured and the bleaching
loaded with Integrity temporary material photographs were taken and alginate trays were made. Opalescence PF 20%
(Dentsply Caulk) and inserted over the impressions were made (Figure 9) to be (Ultradent Inc) bleaching gel was dis-
preparations. enclosed with the case for the ceramist. pensed with proper instruction for
After the provisionals had been Measurements of the length of the cen- home use. The patient was then
properly shaped and polished, they trals also were documented, and the appointed for a shade-taking visit.
were set aside. At this point, the patient patient’s consent to have the treatment At the crown-delivery appoint-
was seated upright and posterior bite completed was obtained. ment, the vital signs were acquired and
CONTEMPORARY ESTHETICS | SEPTEMBER 2007 45
4. CASE STUDY
Red (Global Dental Products) before Acknowledgments
being coated with Gluma De- The author would like to thank
sentisizer (Heraeus Kulzer, Inc). The Ann Le for her ever-present support,
crowns were then blasted with alu- Tom and Beatrice Dabrowsky, LDT,
minum oxide, rinsed, cleaned with RDT of B.I.T. Dental Studio, Dillon,
alcohol, dried, and were cemented Colorado, for the beautiful ceramics,
with RelyX Unicem (3M ESPE). and all my teachers over the years.
After all excess cement was cleaned
Figure 13—Retracted view, final crowns
off, the patient was seated upright References
immediately after cementation. and the occlusion was checked and 1. Henderson RD, Drisko CH, Greenwell H. Root cov-
erage using Alloderm acellular dermal graft mate-
adjusted. Proper centric occlusion, rial. J Contemp Dent Pract. 1999;1(1):24-30.
cuspid, and protrusive guidance were 2. Dodge JR, Henderson R, Greenwell H. Root cover-
verified (Figures 12 through 14). The age without palatal donor site using an acellular
dermal graft. Periodontal Insights. 1998;5(4):5-8.
patient was given detailed instruc- 3. Harris RJ. Root coverage with a connective tissue
tions on proper care and mainte- with partial thickness double pedicle graft and an
acellular dermal matrix graft: a clinical and histo-
nance of the crowns to ensure logical evaluation of a case report. J Periodontol.
longevity. He was then appointed for 1998;69(11):1305-1311.
a postdelivery check-up and final 4. Tal H. Subgingival acellular dermal matrix allograft
for the treatment of gingival recession: a case
Figure 14—Palatal view, final crowns. photographs. At that appointment, report. J Periodontol. 1999;70(9):1118-1124.
the patient expressed his happiness 5. Harris RJ. A comparative study of root coverage
obtained with an acellular dermal matrix versus a
with the final result. connective tissue graft: results of 107 recession
documented, and the procedure was defects in 50 consecutively treated patients. Int J
reviewed again with the patient. Before Conclusion Periodontics Restorative Dent. 2000;20(1):51-59.
6. Grisi DC, Molina GO, Souza SL, et al. Comparative
anesthesia administration, the crowns Complex dental rehabilitation 6-month clinical study of a subepithelial connective
were shown to the patient to have his poses many unique challenges to cli- tissue graft and acellular dermal matrix graft for
the treatment of gingival recession. J Periodontol.
preliminary approval of the forms and nicians. It tests one’s knowledge, 2001;72(11):1477-1484.
shades (Figures 10 and 11). training, integrity, and artistic abili- 7. Mahn DH. Treatment of gingival recession with a
After local anesthesia with Cita- ty. With the variety of treatment modified “tunnel” technique and an acellular der-
mal connective tissue allograft. Pract Proced
nest Plain (Dentsply Pharmaceutical) options currently available, treat- Aesthet Dent. 2001;13(1):69-74.
and Xylocaine 2% with 1:100,000 epi- ment plans can vary from office to 8. Aichelmann-Reidy ME, Yukna RA, Evans GH, et al.
Clinical evaluation of acellular allograft dermis for
nephrine (Dentsply Pharmaceutical), office. Differences in training, phi- the treatment of human gingival recession. J
the temporary crowns were removed losophy, degree of financial motiva- Periodontol. 2001;72(8):998-1005.
and the porcelain crowns were tried in. tion, and esthetic perception by the 9. Woodyard JG, Greenwell H, Hill M, et al. The
clinical effect of acellular dermal matrix on gingi-
The patient was given a hand mirror to dentist as well as the patient also can val thickness and root coverage compared to
evaluate the appearance of the crowns affect treatment plans. Further, the coronally positioned flap alone. J Periodontol.
2004;75(1):44-56.
in place. patient’s personality, financial con- 10. Silverstein LH, Kurtzman GM. A review of dental
After approval for cementation cerns, and personal situation also suturing for optimal soft-tissue management.
was obtained, the crowns were come into play. Nonetheless, with Compend Contin Educ Dent. 2005;26(3):163-166,
169-170.
checked for proper fit, interproximal today’s esthetic demand from the 11. Silverstein LH. Essential principles of dental sutur-
contact, and marginal seal. Because public as well as great advancement ing for the implant surgeon. Dent Implantol Update.
2005;16(1):1-7.
the crowns were ceramometallic, in tissue engineering, clinicians 12. Silverstein LH. Principles of Dental Suturing: The
rubber dam isolation was not neces- should consider regenerative peri- Complete Guide to Surgical Closure. Mahwah, NJ:
sary. The working area was isolated odontics before extracting teeth and Montage Media;1999.
13. Nevins M. Aesthetic and regenerative oral plastic
with cotton rolls and the prepara- communicate this option to their surgery: clinical applications in tissue engineering.
tions were cleaned with Tubulicid patients.13 Gc Dent Today. 2006;25(10):142-146.
46 CONTEMPORARY ESTHETICS | SEPTEMBER 2007
5. CASE STUDY
Product References Products: Imprint Garant, RelyX Unicem
Product: Alloderm Product: Bard-Parker blade No.15C Manufacturer: 3M ESPE
Manufacturer: BioHorizons, Inc Manufacturer: BD Location: St. Paul, Minnesota
Location: Birmingham, Alabama Location: Franklin Lakes, New Jersey Phone: 888.364.3577
Phone: 205.967.7880 Phone: 201.847.6800 Web site: www.3m.com/dental
Web site: www.biohorizons.com Web site: www.bd.com
Product: Integrity
Products: 4% Citanest Plain, Citanest Plain, Product: 5-0 vicryl suture Manufacturer: Dentsply Caulk
Xylocaine 2% with 1:100,000 epinephrine Manufacturer: Ethicon, Inc Location: Milford, Delaware
Manufacturer: Dentsply Pharmaceutical Location: Somerville, New Jersey Phone: 800.532.2855
Location: York, Pennsylvania Web site: www.ethicon.com Web site: www.caulk.com
Phone: 800.225.2787
Web site: www.dentsplypharma.com Products: Retraction cord, GingiBRAID 000 and 00 Product: TempBond Clear
Manufacturer: Dux Dental Manufacturer: Kerr Corporation
Product: Marcaine 0.5% with 1:200,000 epinephrine Location: Oxnard, California Location: Orange, California
Manufacturer: Abbott Laboratories Phone: 800.833.8267 Phone: 800.537.7123
Location: Abbott Park, Illinois Web site: www.duxdental.com Web site: www.kerrdental.com
Web site: www.abbott.us
Product: Zoom! Advanced Power system
Manufacturer: Discus Dental
Location: Culver City, California
Phone: 800.422.9448
Web site: www.discusdental.com
Product: Opalescence PF 20%
Manufacturer: Ultradent, Inc
Location: South Jordan, Utah
Phone: 888.230.1420
Web site: www.ultradent.com
Product: Tubulicid Red
Manufacturer: Global Dental Products
Location: North Bellmore, New York
Phone: 516.221.8844
Web site: www.gdpdental.com
Product: Gluma Desentisizer
Manufacturer: Heraeus Kulzer, Inc
Location: Armonk, New York
Phone: 800.431.1785
Web site: www.heraeus-kulzer-us.com
48 CONTEMPORARY ESTHETICS | SEPTEMBER 2007