This presentation by José Maria Marín-Quemada, Chairman Comisión Nacional de los Mercados y la Competencia, Spain, was made during the discussion on " Cartels: The estimation of harm in public enforcement actions " held at the 2017 Latin American and Caribbean Competition Forum (4-5 April 2017 – Managua, Nicaragua). More papers and presentations can be found at oe.cd/laccf.